Research progress of 24-hour movement behaviors in chronic non-communicable disease

Chronic non-communicable diseases(NCDs)represent a significant impediment to improve life expectancy and remain a focal point in global public health and disease prevention efforts.24-hour movement behaviors,which include sleep,sedentary behavior(SED),and physical activity,underscore the inherent connections between different daily activities and the comprehensive impact of overall movement patterns on health.Evidence suggested that modifying patterns of 24-hour movement behaviors can aid in preventing and attenuating the progression of NCDs.This study systematically delineated the concept,evolution,analytical methods,and intrinsic associations of 24-hour movement behaviors,emphasizing their pivotal role in the prevention and management of NCDs such as obesity,mental disorders,cardiovascular diseases,diabetes,and renal diseases.Future research endeavors should focus on refining methodologies,broadening study populations,developing research tools,and exploring precise intervention strategies and interdisciplinary approaches to comprehensively enhance the effectiveness of NCDs prevention and management from a temporal perspective.Such efforts are poised to provide substantive guidance and support for public health practices.

Associations between meeting 24-hour movement guidelines and quality of life among children and adolescents with autism spectrum disorder

Background:The Canadian 24-hour movement behavior(24-HMB)guidelines suggest that a limited amount of screen time use,an adequate level of physical activity(PA),and sufficient sleep duration are beneficial for ensuring and optimizing the health and quality of life(QoL)of children and adolescents.However,this topic has yet to be examined for children and adolescents with autism spectrum disorder(ASD)specifically.The aim of this cross-sectional observational study was to examine the associations between meeting 24-HMB guidelines and several QoLrelated indicators among a national sample of American children and adolescents with ASD.Methods:Data were taken from the 2020 U.S.National Survey of Children’s Health dataset.Participants(n=956)aged 617 years and currently diagnosed with ASD were included.The exposure of interest was adherence to the 24-HMB guidelines.Outcomes were QoL indicators,including learning interest/curiosity,repeating grades,adaptive ability,victimization by bullying,and behavioral problems.Categorical variables were described with unweighted sample counts and weighted percentages.Age,sex,race,preterm birth status,medication,behavioral treatment,household poverty level,and the educational level of the primary caregivers were included as covariates.Odds ratio(OR)and 95%confidence interval(95%CI)were used to present the strength of association between adherence to 24-HMB guidelines and QoL-related indicators.Results:Overall,452 participants(45.34%)met 1 of the 3 recommendations,216(22.65%)met 2 recommendations,whereas only 39 participants(5.04%)met all 3 recommendations.Compared with meeting none of the recommendations,meeting both sleep duration and PA recommendations(OR=3.92,95%CI:1.639.48,p<0.001)or all 3 recommendations(OR=2.11,95%CI:1.034.35,p=0.04)was associated with higher odds of showing learning interest/curiosity.Meeting both screen time and PA recommendations(OR=0.15,95%CI:0.040.61,p<0.05)or both sleep duration and PA recommendations(OR=0.24,95%CI:0.070.87,p<0.05)was associated with lower odds of repeating any grades.With respect to adaptive ability,participants who met only the PA recommendation of the 24-HMB were less likely to have difficulties dressing or bathing(OR=0.11,95%CI:0.020.66,p<0.05)than those who did not.For participants who met all 3 recommendations(OR=0.38,95%CI:0.150.99,p=0.05),the odds of being victimized by bullying was lower.Participants who adhered to both sleep duration and PA recommendations were less likely to present with severe behavioral problems(OR=0.17,95%CI:0.040.71,p<0.05)than those who did not meet those guidelines.Conclusion:Significant associations were found between adhering to 24-HMB guidelines and selected QoL indicators.These findings highlight the importance of maintaining a healthy lifestyle as a key factor in promoting and preserving the QoL of children with ASD.

7例脑死亡患者24小时AEEG与TCD、BAEP、SLSEP检测分析

目的:探讨24小时动态脑电图(24小时AEEG)在脑死亡判定中的临床应用价值。方法:回顾分析我院收治7例深昏迷患者24小时AEEG与TCD(经颅多普勒超声)、BAEP(脑干听觉诱发电位)、SLSEP(正中神经短潜伏期体感诱发电位)检测情况,并对资料进行分析整理。结果:24小时AEEG监测示为2vu以下脑电活动,均为广泛重度异常动态脑电图。结合TCD、BAEP、SLSEP检测结果,最终临床判定脑死亡,终止临床治疗。结论:24小时AEEG对脑功能的早期判定、预后及"脑死亡"判定具有重要参考价值,结合TCD、BAEP、SLSEP检测可以弥补临床判定技术上的不足,更准确地对脑死亡进行判定。

Interdialytic 24-Hours Ambulatory Blood Pressure versus Dialysis Unit Blood Pressure for the Diagnosis of Electrocardiographic-Left Ventricular Hypertrophy in Chronic Hemodialysis Black Patients

Background and Aim: In hemodialysis patients, 24-hours interdialytic ABPM better detects TOD than dialysis unit blood pressure. Therefore, the present study was aimed to assess the diagnostic performance of 24-hours ABPM vs. dialysis unit BPs for the diagnosis of ECG-LVH in steady state chronic hemodialysis black patients. Methods: From March 31 to September 30, 2018, interdialytic ABPM was performed after a mid-week hemodialysis session for 24 hours using a Spacelab 90207 ABPM monitor in the non-access arm in 45 stable chronic hemodialysis black patients (age ≥ 20 years, hemodialysis for at least 3 months and informed consent) attending 3 hemodialysis centers in Kinshasa. Ambulatory BP was recorded every 20 minutes during the day (6 AM to 10 PM) and every 30 minutes during the night (10 PM to 6 AM). ECG-LVH was defined using Cornell product criteria. ROC curve method was used to assess the performance of dialysis unit BPs vs. interdialytic 24-hours ABPM in diagnosing ECG-LVH. P 0.05 defined the level of statistical significance. Results: Whatever the method of BP measurement, all the SBP values were related to ECG-LVH with similar AUC and overlapping 95% CI;however, they were not significantly different from each other. 24-hours interdialytic ambulatory SBP (AUC 0.748;95% CI 0.58 - 0.94) had the highest area under the curve. Conclusion: The present study showed that although all the two BP measurement methods equally detected ECG-LVH, 24-hours ABPM tended to have the highest diagnostic performance.

The nurses’ voice of working in a newly established community based 24-hour support center for people with psychiatric disabilities

This study explores the perceptions of a small group of nurses working at a newly established 24-hour community-based service enter (SC) for users with psychiatric disability using a qualitative approach. Since the mental health reform in Sweden in 1995 where the communities (in Sweden called municipalities) were given the responsibility to establish service and support to people with severe psychiatric disabilities, they have struggled in finding suitable forms of these kinds of areas. In 2010, this led to the creation and development of a new center aiming to provide services and support based on the expressed needs of people with physchiatric disability in a community located in southern Sweden. During 2011, a total of three group interviews were performed to capture the employed nurses’ perceptions of this newly established SC. The interview texts were analyzed by way of qualitative content analysis. A first reading of the interview texts revealed that the nurses’ perceptions of the service center were unwaveringly positive but that their beliefs about who the specific target group were differed. The main finding was summarized by the theme: Making a difference—on an individual, professional, and organizational level. The sub themes were: 24-hour availability, unclear assignment, and preventing mental illness. The findings indicate a need for a community round-the-clock service center in this Swedish community and a more clear definition of the target group.

China introduces the 24-hour rule

Recently, international movement measures that may be causing tension between the of cargo had been the subject of increasing border control needs for security and the needs for trade facilitations. On the one hand customs authorities are charged with the responsibility for policing a country＇s borders, and consequently they need to have in place measures to ensure that only legitimate trade takes place and that this trade does not present security concerns. On the other hand we have the requirements of traders, who benefit from an environment of trade facilitation with speedy and efficient movement of cargo across international borders, with minimal bureaucratic intervention. This paper focuses on and provides early discussion and comments on the possible ramifications of the introduction of the 24-hour rule in China, effective for all exports and imports of sea freight container traffic since January 1, 2009. The new rules will have significant impact on the logistics flows of exporters and importers alike. Specifically, the reporting requirements timelines are likely to result in increased costs in cargo processing at wharves that traders will have to bear; place added pressure on storage facilities at wharves, or at container depots; and may additionally increase the amount of inventory buffer because of the timing of the data reporting requirements. The paper concludes that security needs have prevailed over trade facilitation considerations and that traders should urgently implement a review of existing practices to ensure they comply with the China Customs requirements, whilst simultaneously minimizing cost increases.

The lived experience of a 24-hour support center for persons with psychiatric disabilities: Making me feel almost like an ordinary person

This study illuminates nine psychiatric disabled persons’ lived experience of a newly established community-based service center open around the clock. This new 24-hour support center (SC) was established in 2011 in a Swedish community to better match and facilitate the disabled persons’ needs. In order to illuminate the disabled person’s experiences individual interview was performed. A phenomenological-hermeneutical method inspired by Paul Ricoeur was used to interpret the texts. After a naive reading, a structural analysis revealed two themes: 1), becoming aware of myself as a person, and 2) having a lifeline and belongingness. The comprehensive understanding was interpreted as meaning “Making me feel almost like an ordinary person”, which incorporated the person’s past with their present together with a direction for the future and hope for a more fulfilling life.

Esophageal manometry and 24-hour pH monitoring in esophagus surgery:28-year Chinese experience in a single center

Objective To retrospectively review the experience of esophageal manometry and 24-hour pH monitoring in e-sophagus surgery. Methods From 1982 to 2010,patients with unspecific chest pain and undergone esophageal surgery were received esophageal manometry and 24-hour pH monitoring. Results Among the patients with

24h动态脑电图在小儿癫痫与非癫痫性疾病中的诊断价值

目的探讨24h动态脑电图在小儿癫痫与非癫痫发作性疾病临床诊断中的价值。方法选取2011—2012年我院收治的137例患儿,根据诊断分为癫痫组与疑似癫痫组。结果 137例患儿中脑电图异常的检出率为63.5%。癫痫组患儿异常率为88.51%,癫痫样放电检出率为83.91%;疑似癫痫组患儿异常率为42%,癫痫样放电检出率为28%。癫痫组异常率与癫痫样放电检出率均显著高于疑似癫痫组(P<0.05)。结论 24h动态脑电图能够有效诊断小儿癫痫,对癫痫鉴别诊断有重要的临床价值。

24小时动态脑电图对小儿非癫痫性发作性疾病的诊断价值

目的:提高临床医师对小儿非癫痫性发作性疾病的认识。方法:对2009年1月～2010年8月我院就诊的299例年龄在49 d～5岁之间拟诊或需排除癫痫的患儿进行动态脑电图(AEEG)监测,依据国际抗癫痫联盟(ILAE)关于癫痫和癫痫综合征的分类标准,分为非癫痫性发作性疾病150例,癫痫125例,热性惊厥24例。结果:299例中非癫痫性发作性疾病150例,其中主要为非癫痫性强直样发作、睡眠肌阵挛、脑发育不良及脑损伤引起的发作性抖动、小儿屏气发作、心因性发作、触觉或情绪诱发性运动障碍、电解质紊乱、晕厥、小儿夜惊等;AEEG监测到发作间期正常99例,癫痫样放电37例,非特异性改变14例;同期监测到60例有临床发作的病例均不伴异常放电。结论:动态脑电图能有效地诊断非癫痫性发作,可提高临床医师对该疾病的认识。

24小时动态脑电图对儿童抽动障碍患者病情的评估价值研究

目的回顾性分析抽动障碍儿童的临床与脑电图特征。方法观察92例抽动障碍患儿的临床症状,并利用24小时动态脑电图仪记录其脑电图改变。结果短暂性抽动症、慢性抽动症及多发性抽动症患儿脑电图异常率相比较,慢性抽动症或多发性抽动症患儿在脑电图表现上其异常率明显高于短暂性抽动症,其差异有统计学意义(P<0.05)。结论抽动障碍患儿脑电图上的异常表现与病情的严重程度、患病时间有一定关系,24小时动态脑电图亦可作为判断儿童抽动障碍病情程度的客观指标。

应用24 h动态脑电图检查小儿癫痫及其临床特征分析

目的:分析24 h动态脑电图(24 hours ambulatory electroencephalogram,24 h AEEG)检查小儿癫痫及其临床特征。方法:择取本院2017年10月-2019年10月接收的疑似癫痫患儿180例,予以24 h AEEG监测,记录患儿的痫样放电情况、放点特征、癫痫所属类型及病灶的定位位置。结果:(1)180例疑似癫痫患儿中,108例监测存在痫样放电情况,其中28例为清醒阶段痫样放电;睡眠阶段痫样放电70例,睡眠阶段及清醒阶段均出现痫样放电,占比9.26%;(2)108例测定到痫样放电的疑似患儿中,因脑梗死、颅内细菌感染、颅内出血等器质性病变导致的痫样放电55.56%,代谢疾病发生痫样放电18.52%;因感染发生痫样放电14.81%,其余类型11.11%;(3)180例疑似癫痫患儿中,98例测定到同步的临床反应中有69例同时监测出痫样放电状态,可诊断为癫痫;其余29例同步的临床反应中未测定到痫样放电,疑似癫痫,需进行多次测定即可确诊;(4)根据同步临床反应、测定结果,69例确诊为癫痫。结论:熟练掌握小儿癫痫24 h动态脑电图临床特征,能更好地提升对癫痫的认知,精准进行癫痫的分型和病灶定位。

Dietary Surveys Carried out among Diabetic Patients Hospitalized in the Metabolic and Endocrine Diseases Department of the C.H.U-B

A varied and balanced diet has always been essential in the optimal management of diabetes. The objective of this work was to evaluate dietary surveys among 50 diabetic patients hospitalized in the metabolic and endocrine diseases department of the Brazzaville Hospital and University Center. This survey was carried out using two methods: dietary history and 24-hour recall. The results relating to the dietary history revealed in the patients a dietary imbalance characterized by snacking at meals, non-compliance with a balanced diet and a high frequency of consumption of foods rich in simple sugar. and saturated fats. Regarding the 24-hour recall, the survey showed that the average blood sugar levels of hospitalized patients increased depending on the number of meals. This meant that these hyperglycemias (2 to 5 g/L) observed in these patients exceeded three meals per day and required, among other things, an increase in insulin intake or doses. The age groups of diabetic patients were also divided. These age groups had partly defined the types of diabetes encountered. Regarding body mass index, women had a body mass index greater than 30 kg/m2 compared to men. This increase in body mass index was explained by being overweight or even obese due to excess body fat.

AEEG、SPECT及神经影像学检查在癫痫诊断中的应用

目的 观察 2 4h动态脑电图 (AmbulatoryelectroencephalographyAEEG)、单光子发射计算机断层扫描(Singlephotonemissioncomputedtomography ,SPECT)、头颅CT或MR检查在癫痫诊断中的价值。方法 52例已确诊的癫痫患者 ,部分性发作 4例 ,全面性发作 48例 ;分别施行 2 4h动态脑电图、发作间期SPECT、头颅CT或MR检查 ,观察此 4种诊断方案应用的阳性检出率及互相之间的关系。结果 2 4h动态脑电图检查显示 ,52例患者中 50例 (96 15% )记录到癫痫样波形 ,SPECT扫描 ,44例患者 (84 62 % )在发作间期可见局限性脑血流灌注降低区。两种诊断方法阳性检出率比较 ,差异无显著性意义 (P >0 0 5) ,AEEG癫痫样波形发放区与发作间期SPECT血流灌注降低区定位符合率差异无显著性意义 (P <0 1)。CT或MR检查仅 5例患者有确定的病灶。与AEEG癫痫样波形发放部位及发作间期SPECT局限性脑血流灌注降低区相符。结论 2 4h动态脑电图、发作间期SPECT与CT或MR检查联合应用 。

24小时动态脑电图对儿童外侧裂癫癎的诊断价值及随访观察

目的:探讨24小时动态脑电图对儿童外侧裂癫癎的诊断价值及随访观察。方法:对105例临床诊断为儿童外侧裂癫癎的患儿进行常规脑电图和24小时动态脑电图检查,并对检查结果进行对比分析。结果:常规脑电图描记时出现异常放电21例(20%),在24小时动态脑电图描记时,全部病例均有异常放电,在随访观察中,儿童外侧裂癫癎临床发作停止2年脑电图异常放电会消失。结论:24小时动态脑电图对儿童外侧裂癫癎有重要诊断价值。

补中益气汤对阿霉素诱导的大鼠肾病的作用

以阿霉素肾病大鼠模型为研究对象,采用了血液生化学和组织病理学方法,分析了补中益气汤对阿霉素肾病的作用和可能的机制.Wistar雄性大鼠60只,随机分为对照组(n=10)、模型组(n=10)、激素组(n=10)和补中益气汤低剂量组(n=10)、中剂量组(n=10)和高剂量组(n=10).采用阿霉素二次尾静脉注射法(首次6mg/kg,二次3mg/kg)制作阿霉素肾病的大鼠模型.在阿霉素注射后7,21,42d将大鼠置于代谢笼中分别收集24h尿液,测定24h尿蛋白.末次给药后,眼眶取血检测肾功能指标,包括肌肝SCR(serum creatine)和尿素氮BUN(blood urea nitrogen);处死大鼠并观察肾组织病理改变.结果表明:补中益气汤可以显著减少尿蛋白的排泄并缓解肾皮质上皮细胞的病理学改变.这提示补中益气汤对阿霉素大鼠能够通过改善尿蛋白的排泄,缓解肾脏病理改变,从而起到对肾脏的保护作用.

儿童非癫痫性发作事件的临床与动态脑电监测

目的：探讨24小时动态脑电监测对儿童非癫痫性发作事件的诊断价值。方法：应用24小时动态脑电监测对133例儿童非癫痫性发作事件（惊厥、头痛、晕厥、夜惊和夜游症）进行跟踪监测，分析各时态脑电活动情况。结果：非特异性异常（25％）：惊厥12例（34％），头痛11例（33％），李厥5例（21％），夜惊4例（17％），夜游症2例（11％）。痫样放电13（10%）：惊厥5例（14），头痛2例（6％），晕厥3例（12％），夜惊2例（9％），夜游症1例（6％）。非特异性异常和痫样放电检出率以小儿惊厥最高。结论：24小时动态脑电监测有助于儿童非癫痫性发作事件的诊断和鉴别诊断。

Association between endogenous cortisol level and the risk of central serous chorioretinopathy:a Meta-analysis

AIM： To assess the association between endogenous cortisol level and the risk of central serous chorioretinopathy（CSC）.METHODS： Case-control studies were systematically searched on PubM ed, Embase, Cochrane, China National Knowledge Infrastructure（CNKI） for publishes between January 1990 and July 2017 to assess the association between endogenous cortisol level and CSC. The main endpoints were serum cortisol level at 8 a.m. and 24-hour urine 17-hydroxysteroids level. We assessed pooled data using a random-effects model.RESULTS： Of 86 identified studies, 5 were eligible included in our analysis. The 5 studies included a total of 315 participants, of whom 187 had CSC. Statistically significant association was observed between serum cortisol level（summary SMD=0.77, 95%CI=0.55-0.99）, 24-hour urine 17-hydroxysteroids level（summary SMD=0.95, 95%CI=0.61-1.30）, and the risk of CSC.CONCLUSION： Endogenous cortisol level is associated with an increased risk of CSC. Combined treatment targeting the serum cortisol level at 8 a.m. and 24-hour urine 17-hydroxysteroids level can be a potential preventive strategy for individuals who are at risk of CSC and therapeutic strategy for patients with CSC.