<div style="text-align:justify;"> <strong>Introduction-Purpose: </strong><span "="">Pulsed pressure is recognized as an important predictor of cardiovascular risk. The ...<div style="text-align:justify;"> <strong>Introduction-Purpose: </strong><span "="">Pulsed pressure is recognized as an important predictor of cardiovascular risk. The purpose of this study was to identify a possible association between high ambulatory pulsed pressure and left ventricular geometry change in African black people. <b>Material and methods:</b> We conducted a bicentric, retrospective descriptive and analytical study that took place from 2010 to 2015 at the Abidjan Heart Institute and the Polyclinic Sainte Anne Marie in Abidjan. The people were selected from MAPA’s archive files. Those aged 18 years and over were included, all of whom had valid echocardiography and MAPA. The analyzed parameters concerned epidemiological data with age, gender and body surface area. The clinical data analyzed included systolic, diastolic, mean and 24-hours pulsed pressures. On the echocardiographic parameters, it was the evaluation of the ventricular mass indexed to the body surface. <b>Results: </b>A total of 177</span> patients records were selected. The mean age of the patients was 56.32 ± 10.51 years. There was a male predominance with a sex ratio of 1.15. The main cardiovascular risk factors found outside high blood pressure were dyslipidemia (06.87%) and obesity (13.7%). In clinical terms, hypertension was found in 75% of cases (n = 133) versus 25% (n = 44) of normotensive patients. These blood pressure profiles allowed us to classify our study population into two groups:<span "=""> hypertensives people and normotensives people. The hypertensives people had significantly higher mean pulsed pressure levels than the normotensives people. All normotensive patients had normal pulsed pressure. In the hypertensive population, the prevalence of high pulsed pressure was 31% (n = 41) versus 69% (n = 92) normal pulsed pressure. Concerning the relationship between 24 hour ambulatory pulsed pressure and left ventricular mass, hypertensives patients with a high ambulatory pulsed pressure had a significantly higher average indexed ventricular mass than the opposite groups (p = 0.039). Their ejection fraction was significantly lower than those of the opposite populations (p = 0.000). On the analysis of the correlation between the left ventricular mass and the tension profile, we noted in our series, a strong and significant correlation (r = 0.6342;p = 0.0000) between pulsed pressure and the ventricular geometry change. <b>Conclusion: </b>High ambulatory pulsed pressure remains an independent factor of change in left ventricular geometry in black people.</span> </div>展开更多
Objective: To investigate blood pressure variability of Elder hypertensives with type 2 diabetes and its relationship with cognition. Methods: A total of 143 elderly hypertensives were enrolled and divided into diabet...Objective: To investigate blood pressure variability of Elder hypertensives with type 2 diabetes and its relationship with cognition. Methods: A total of 143 elderly hypertensives were enrolled and divided into diabetic group (59 cases) and non-diabetic group (84 cases). The difference of general clinical characteristics, biochemical parameters, carotid ultrasound, a neuropsychological Scales and 24-hour ambulatory blood pressure (24hABPM) parameters between the two groups of subjects were compared. Then, the two groups (diabetic group and non-diabetic group) were further divided into (Mild cognitive dysfunction) subgroup (MMSE>26) and normal cognition subgroup (MMSE≤26), respectively. On the basis of MMSE scores, the difference of the parameters of ABPM between the two subgroups was analyzed. Results: Compared with the control group, 24hSBP, 24hPP, dSBP, dPP, nSBP, nPP, 24hSSD, dSSD, nSSD, 24hSCV, dSCV and nSCV were significantly higher in the diabetic group (p<0.05). However, cognition was lower in the diabetic group. No significant difference was found in the circadian pattern of blood pressure between the two groups. 24hSSD, dSSD, nSSD, 24hSCV, dSCV, nSCV were significantly higher in the MCI subgroup than normal cognition subgroup in both diabetic and non-diabetic groups(p<0.05), and they were negatively associated with scores of MMSE, the correlation coefficient were -0.235,-0.246,-0.341,-0.158,-0.222,-0.238 (0.001≤P<0.05). Conclusion: The study showed that in the elderly with hypertension, the mean systolic blood pressure and blood pressure variability were both higher in the diabetic group, and the cognition was lower instead. Whether or not with diabetes, blood pressure variability was always higher in the MCI subgroup. Blood pressure variability increased in patients with diabetes, and was associated with cognitive decline.展开更多
目的观察未合并高血压的糖耐量减低患者24 h血压改变情况。方法回顾分析2005～2007年入院查体患者162例,根据空腹血糖、口服葡萄糖耐量试验(OGTT)或餐后2 h血糖分为健康对照组40例,无高血压的糖耐量减低组37例,无高血压的糖尿病组45例,...目的观察未合并高血压的糖耐量减低患者24 h血压改变情况。方法回顾分析2005～2007年入院查体患者162例,根据空腹血糖、口服葡萄糖耐量试验(OGTT)或餐后2 h血糖分为健康对照组40例,无高血压的糖耐量减低组37例,无高血压的糖尿病组45例,无糖耐量减低的高血压组40例,记录各组的血脂(TG、TC、HDL、LDL)、偶测血压数值,采用动态血压监测仪记录24 h动脉血压并测量24 h平均收缩压(24 h SBP)、24 h平均舒张压(24 h DBP)及24 h动态脉压(24 h PP)。结果(1)糖耐量减低组与糖尿病组的TG高于健康对照组和高血压组,差异有统计学意义(P<0.05)。(2)糖耐量减低组24 h SBP及24 hDBP与健康对照组差异有统计学意义(P<0.01),而与高血压组差异无统计学意义(P>0.05)。糖耐量减低组24 h PP与高血压组差异无统计学意义(P>0.05)。结论糖耐量减低患者在临床明确诊断高血压前已发生血压调节的明显改变。展开更多
目的分析白大衣高血压(WCH)患者动态脉压(APP)及动态脉压指数(APPI)的特征,探讨WCH对血管硬化的影响。方法WCH患者60例、高血压I级患者60例(高血压组)和血压正常者50名(对照组)入选本研究,测量其诊室血压和动态血压,对各组APP及APPI进...目的分析白大衣高血压(WCH)患者动态脉压(APP)及动态脉压指数(APPI)的特征,探讨WCH对血管硬化的影响。方法WCH患者60例、高血压I级患者60例(高血压组)和血压正常者50名(对照组)入选本研究,测量其诊室血压和动态血压,对各组APP及APPI进行组间比较。结果WCH组和高血压组患者的诊室脉压及脉压指数高于对照组(P<0.01),且WCH组高于高血压组(P<0.01);高血压组患者24 h APP大于WCH组和对照组(P<0.01),WCH组患者的白天动态脉压(dAPP)大于对照组(P<0.01),高血压组患者24 h APPI、白天APPI(dAPPI)和夜间APPI(nAPPI)均大于WCH组和对照组(P<0.01),WCH组24 h APPI、dAPPI和nAPPI亦均大于对照组(P<0.05)。结论WCH不同于正常人群,会对血管造成一定程度的损伤,引起血管硬化,但其危害程度小于高血压,造成的损伤作用白天更明显。展开更多
文摘<div style="text-align:justify;"> <strong>Introduction-Purpose: </strong><span "="">Pulsed pressure is recognized as an important predictor of cardiovascular risk. The purpose of this study was to identify a possible association between high ambulatory pulsed pressure and left ventricular geometry change in African black people. <b>Material and methods:</b> We conducted a bicentric, retrospective descriptive and analytical study that took place from 2010 to 2015 at the Abidjan Heart Institute and the Polyclinic Sainte Anne Marie in Abidjan. The people were selected from MAPA’s archive files. Those aged 18 years and over were included, all of whom had valid echocardiography and MAPA. The analyzed parameters concerned epidemiological data with age, gender and body surface area. The clinical data analyzed included systolic, diastolic, mean and 24-hours pulsed pressures. On the echocardiographic parameters, it was the evaluation of the ventricular mass indexed to the body surface. <b>Results: </b>A total of 177</span> patients records were selected. The mean age of the patients was 56.32 ± 10.51 years. There was a male predominance with a sex ratio of 1.15. The main cardiovascular risk factors found outside high blood pressure were dyslipidemia (06.87%) and obesity (13.7%). In clinical terms, hypertension was found in 75% of cases (n = 133) versus 25% (n = 44) of normotensive patients. These blood pressure profiles allowed us to classify our study population into two groups:<span "=""> hypertensives people and normotensives people. The hypertensives people had significantly higher mean pulsed pressure levels than the normotensives people. All normotensive patients had normal pulsed pressure. In the hypertensive population, the prevalence of high pulsed pressure was 31% (n = 41) versus 69% (n = 92) normal pulsed pressure. Concerning the relationship between 24 hour ambulatory pulsed pressure and left ventricular mass, hypertensives patients with a high ambulatory pulsed pressure had a significantly higher average indexed ventricular mass than the opposite groups (p = 0.039). Their ejection fraction was significantly lower than those of the opposite populations (p = 0.000). On the analysis of the correlation between the left ventricular mass and the tension profile, we noted in our series, a strong and significant correlation (r = 0.6342;p = 0.0000) between pulsed pressure and the ventricular geometry change. <b>Conclusion: </b>High ambulatory pulsed pressure remains an independent factor of change in left ventricular geometry in black people.</span> </div>
文摘Objective: To investigate blood pressure variability of Elder hypertensives with type 2 diabetes and its relationship with cognition. Methods: A total of 143 elderly hypertensives were enrolled and divided into diabetic group (59 cases) and non-diabetic group (84 cases). The difference of general clinical characteristics, biochemical parameters, carotid ultrasound, a neuropsychological Scales and 24-hour ambulatory blood pressure (24hABPM) parameters between the two groups of subjects were compared. Then, the two groups (diabetic group and non-diabetic group) were further divided into (Mild cognitive dysfunction) subgroup (MMSE>26) and normal cognition subgroup (MMSE≤26), respectively. On the basis of MMSE scores, the difference of the parameters of ABPM between the two subgroups was analyzed. Results: Compared with the control group, 24hSBP, 24hPP, dSBP, dPP, nSBP, nPP, 24hSSD, dSSD, nSSD, 24hSCV, dSCV and nSCV were significantly higher in the diabetic group (p<0.05). However, cognition was lower in the diabetic group. No significant difference was found in the circadian pattern of blood pressure between the two groups. 24hSSD, dSSD, nSSD, 24hSCV, dSCV, nSCV were significantly higher in the MCI subgroup than normal cognition subgroup in both diabetic and non-diabetic groups(p<0.05), and they were negatively associated with scores of MMSE, the correlation coefficient were -0.235,-0.246,-0.341,-0.158,-0.222,-0.238 (0.001≤P<0.05). Conclusion: The study showed that in the elderly with hypertension, the mean systolic blood pressure and blood pressure variability were both higher in the diabetic group, and the cognition was lower instead. Whether or not with diabetes, blood pressure variability was always higher in the MCI subgroup. Blood pressure variability increased in patients with diabetes, and was associated with cognitive decline.
文摘目的观察未合并高血压的糖耐量减低患者24 h血压改变情况。方法回顾分析2005～2007年入院查体患者162例,根据空腹血糖、口服葡萄糖耐量试验(OGTT)或餐后2 h血糖分为健康对照组40例,无高血压的糖耐量减低组37例,无高血压的糖尿病组45例,无糖耐量减低的高血压组40例,记录各组的血脂(TG、TC、HDL、LDL)、偶测血压数值,采用动态血压监测仪记录24 h动脉血压并测量24 h平均收缩压(24 h SBP)、24 h平均舒张压(24 h DBP)及24 h动态脉压(24 h PP)。结果(1)糖耐量减低组与糖尿病组的TG高于健康对照组和高血压组,差异有统计学意义(P<0.05)。(2)糖耐量减低组24 h SBP及24 hDBP与健康对照组差异有统计学意义(P<0.01),而与高血压组差异无统计学意义(P>0.05)。糖耐量减低组24 h PP与高血压组差异无统计学意义(P>0.05)。结论糖耐量减低患者在临床明确诊断高血压前已发生血压调节的明显改变。
文摘目的分析白大衣高血压(WCH)患者动态脉压(APP)及动态脉压指数(APPI)的特征,探讨WCH对血管硬化的影响。方法WCH患者60例、高血压I级患者60例(高血压组)和血压正常者50名(对照组)入选本研究,测量其诊室血压和动态血压,对各组APP及APPI进行组间比较。结果WCH组和高血压组患者的诊室脉压及脉压指数高于对照组(P<0.01),且WCH组高于高血压组(P<0.01);高血压组患者24 h APP大于WCH组和对照组(P<0.01),WCH组患者的白天动态脉压(dAPP)大于对照组(P<0.01),高血压组患者24 h APPI、白天APPI(dAPPI)和夜间APPI(nAPPI)均大于WCH组和对照组(P<0.01),WCH组24 h APPI、dAPPI和nAPPI亦均大于对照组(P<0.05)。结论WCH不同于正常人群,会对血管造成一定程度的损伤,引起血管硬化,但其危害程度小于高血压,造成的损伤作用白天更明显。
