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Research progress of 24-hour movement behaviors in chronic non-communicable disease
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作者 Rong-Xuan Li Qing-Qing Fan Di Cui 《Life Research》 2024年第3期24-34,共11页
Chronic non-communicable diseases(NCDs)represent a significant impediment to improve life expectancy and remain a focal point in global public health and disease prevention efforts.24-hour movement behaviors,which inc... Chronic non-communicable diseases(NCDs)represent a significant impediment to improve life expectancy and remain a focal point in global public health and disease prevention efforts.24-hour movement behaviors,which include sleep,sedentary behavior(SED),and physical activity,underscore the inherent connections between different daily activities and the comprehensive impact of overall movement patterns on health.Evidence suggested that modifying patterns of 24-hour movement behaviors can aid in preventing and attenuating the progression of NCDs.This study systematically delineated the concept,evolution,analytical methods,and intrinsic associations of 24-hour movement behaviors,emphasizing their pivotal role in the prevention and management of NCDs such as obesity,mental disorders,cardiovascular diseases,diabetes,and renal diseases.Future research endeavors should focus on refining methodologies,broadening study populations,developing research tools,and exploring precise intervention strategies and interdisciplinary approaches to comprehensively enhance the effectiveness of NCDs prevention and management from a temporal perspective.Such efforts are poised to provide substantive guidance and support for public health practices. 展开更多
关键词 chronic non-communicable diseases 24-hour movement behaviors time-use epidemiology isotemporal substitution model compositional data analysis
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Associations between meeting 24-hour movement guidelines and quality of life among children and adolescents with autism spectrum disorder 被引量:3
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作者 Chuidan Kong Aiguo Chen +9 位作者 Sebastian Ludyga Fabian Herold Sean Healy Mengxian Zhao Alyx Taylor Notger G.Muller Arthur F.Kramer Sitong Chen Mark S.Tremblay Liye Zou 《Journal of Sport and Health Science》 SCIE CSCD 2023年第1期73-86,共14页
Background:The Canadian 24-hour movement behavior(24-HMB)guidelines suggest that a limited amount of screen time use,an adequate level of physical activity(PA),and sufficient sleep duration are beneficial for ensuring... Background:The Canadian 24-hour movement behavior(24-HMB)guidelines suggest that a limited amount of screen time use,an adequate level of physical activity(PA),and sufficient sleep duration are beneficial for ensuring and optimizing the health and quality of life(QoL)of children and adolescents.However,this topic has yet to be examined for children and adolescents with autism spectrum disorder(ASD)specifically.The aim of this cross-sectional observational study was to examine the associations between meeting 24-HMB guidelines and several QoLrelated indicators among a national sample of American children and adolescents with ASD.Methods:Data were taken from the 2020 U.S.National Survey of Children’s Health dataset.Participants(n=956)aged 617 years and currently diagnosed with ASD were included.The exposure of interest was adherence to the 24-HMB guidelines.Outcomes were QoL indicators,including learning interest/curiosity,repeating grades,adaptive ability,victimization by bullying,and behavioral problems.Categorical variables were described with unweighted sample counts and weighted percentages.Age,sex,race,preterm birth status,medication,behavioral treatment,household poverty level,and the educational level of the primary caregivers were included as covariates.Odds ratio(OR)and 95%confidence interval(95%CI)were used to present the strength of association between adherence to 24-HMB guidelines and QoL-related indicators.Results:Overall,452 participants(45.34%)met 1 of the 3 recommendations,216(22.65%)met 2 recommendations,whereas only 39 participants(5.04%)met all 3 recommendations.Compared with meeting none of the recommendations,meeting both sleep duration and PA recommendations(OR=3.92,95%CI:1.639.48,p<0.001)or all 3 recommendations(OR=2.11,95%CI:1.034.35,p=0.04)was associated with higher odds of showing learning interest/curiosity.Meeting both screen time and PA recommendations(OR=0.15,95%CI:0.040.61,p<0.05)or both sleep duration and PA recommendations(OR=0.24,95%CI:0.070.87,p<0.05)was associated with lower odds of repeating any grades.With respect to adaptive ability,participants who met only the PA recommendation of the 24-HMB were less likely to have difficulties dressing or bathing(OR=0.11,95%CI:0.020.66,p<0.05)than those who did not.For participants who met all 3 recommendations(OR=0.38,95%CI:0.150.99,p=0.05),the odds of being victimized by bullying was lower.Participants who adhered to both sleep duration and PA recommendations were less likely to present with severe behavioral problems(OR=0.17,95%CI:0.040.71,p<0.05)than those who did not meet those guidelines.Conclusion:Significant associations were found between adhering to 24-HMB guidelines and selected QoL indicators.These findings highlight the importance of maintaining a healthy lifestyle as a key factor in promoting and preserving the QoL of children with ASD. 展开更多
关键词 24-hour movement guidelines Autism spectrum disorder Physical activity Quality of life
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外路全周缝线小梁切开术对原发性开角型青光眼患者24h眼压波动规律的影响
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作者 蔺涛 王佳琦 +1 位作者 丁雨帆 刘刚 《国际眼科杂志》 CAS 2024年第8期1324-1327,共4页
目的:评估外路全周缝线小梁切开术(CST)对原发性开角型青光眼(POAG)24 h眼压波动规律的影响。方法:回顾性研究。纳入2021-03/2022-05在我院就诊的药物治疗眼压控制不佳的POAG患者18例18眼,均行CST治疗,分别在术前,术后1 a进行24 h眼压检... 目的:评估外路全周缝线小梁切开术(CST)对原发性开角型青光眼(POAG)24 h眼压波动规律的影响。方法:回顾性研究。纳入2021-03/2022-05在我院就诊的药物治疗眼压控制不佳的POAG患者18例18眼,均行CST治疗,分别在术前,术后1 a进行24 h眼压检查(选择时间点为9∶00 AM、12∶00 AM、3∶00 PM、6∶00 PM、9∶00 PM、12∶00 PM、3∶00 AM、6∶00 AM),比较术前,术后1 a 24 h眼压均值、峰值及峰值时间、谷值及谷值时间、波动范围及昼夜平均眼压差变化。结果:术前,术后1 a 24 h眼压曲线均呈现日间下降、夜间升高的变化趋势,下午降至波谷,夜间升至波峰;与术前相比,术后1 a 24 h眼压谷值、峰值时间较术前提前,术后1 a 24 h眼压均值、峰值、谷值明显下降,波动范围无明显差异,昼夜平均眼压差明显增加。结论:CST可降低POAG患者眼压,但不改变24 h眼压波动范围,反而升高昼夜平均眼压差,提示CST不能改善POAG患者昼夜眼压波动。 展开更多
关键词 原发性开角型青光眼 全周缝线小梁切开术 24 h眼压 昼夜眼压波动
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Interdialytic 24-Hours Ambulatory Blood Pressure versus Dialysis Unit Blood Pressure for the Diagnosis of Electrocardiographic-Left Ventricular Hypertrophy in Chronic Hemodialysis Black Patients 被引量:1
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作者 Cédric Kabemba Ilunga Francois Bompeka Beka Lepira +8 位作者 Jean Robert Rissassi Makulo Yves Lubenga Trésor Mvunzi Noel Utshudi Aliocha Nkodila Vieux Momeme Mokoli Ernest Kiswaya Sumaili Nazaire Mangani Nseka Eleuthère Vita Kintoki 《World Journal of Cardiovascular Diseases》 2019年第11期846-856,共11页
Background and Aim: In hemodialysis patients, 24-hours interdialytic ABPM better detects TOD than dialysis unit blood pressure. Therefore, the present study was aimed to assess the diagnostic performance of 24-hours A... Background and Aim: In hemodialysis patients, 24-hours interdialytic ABPM better detects TOD than dialysis unit blood pressure. Therefore, the present study was aimed to assess the diagnostic performance of 24-hours ABPM vs. dialysis unit BPs for the diagnosis of ECG-LVH in steady state chronic hemodialysis black patients. Methods: From March 31 to September 30, 2018, interdialytic ABPM was performed after a mid-week hemodialysis session for 24 hours using a Spacelab 90207 ABPM monitor in the non-access arm in 45 stable chronic hemodialysis black patients (age ≥ 20 years, hemodialysis for at least 3 months and informed consent) attending 3 hemodialysis centers in Kinshasa. Ambulatory BP was recorded every 20 minutes during the day (6 AM to 10 PM) and every 30 minutes during the night (10 PM to 6 AM). ECG-LVH was defined using Cornell product criteria. ROC curve method was used to assess the performance of dialysis unit BPs vs. interdialytic 24-hours ABPM in diagnosing ECG-LVH. P 0.05 defined the level of statistical significance. Results: Whatever the method of BP measurement, all the SBP values were related to ECG-LVH with similar AUC and overlapping 95% CI;however, they were not significantly different from each other. 24-hours interdialytic ambulatory SBP (AUC 0.748;95% CI 0.58 - 0.94) had the highest area under the curve. Conclusion: The present study showed that although all the two BP measurement methods equally detected ECG-LVH, 24-hours ABPM tended to have the highest diagnostic performance. 展开更多
关键词 24-hours ABPM Dialysis Unit BPs ECG-LVH Diagnostic Performance Chronic Hemodialysis Black Africans
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The nurses’ voice of working in a newly established community based 24-hour support center for people with psychiatric disabilities 被引量:1
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作者 Ann-Christin Janlov Agneta Berg 《Open Journal of Nursing》 2013年第2期195-201,共7页
This study explores the perceptions of a small group of nurses working at a newly established 24-hour community-based service enter (SC) for users with psychiatric disability using a qualitative approach. Since the me... This study explores the perceptions of a small group of nurses working at a newly established 24-hour community-based service enter (SC) for users with psychiatric disability using a qualitative approach. Since the mental health reform in Sweden in 1995 where the communities (in Sweden called municipalities) were given the responsibility to establish service and support to people with severe psychiatric disabilities, they have struggled in finding suitable forms of these kinds of areas. In 2010, this led to the creation and development of a new center aiming to provide services and support based on the expressed needs of people with physchiatric disability in a community located in southern Sweden. During 2011, a total of three group interviews were performed to capture the employed nurses’ perceptions of this newly established SC. The interview texts were analyzed by way of qualitative content analysis. A first reading of the interview texts revealed that the nurses’ perceptions of the service center were unwaveringly positive but that their beliefs about who the specific target group were differed. The main finding was summarized by the theme: Making a difference—on an individual, professional, and organizational level. The sub themes were: 24-hour availability, unclear assignment, and preventing mental illness. The findings indicate a need for a community round-the-clock service center in this Swedish community and a more clear definition of the target group. 展开更多
关键词 Psychiatric Disability Mental Health Nursing Community Mental Health Service 24-hour Service Center Qualitative Content Analysis
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China introduces the 24-hour rule
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作者 Bergami Roberto 《Chinese Business Review》 2009年第3期1-7,共7页
Recently, international movement measures that may be causing tension between the of cargo had been the subject of increasing border control needs for security and the needs for trade facilitations. On the one hand cu... Recently, international movement measures that may be causing tension between the of cargo had been the subject of increasing border control needs for security and the needs for trade facilitations. On the one hand customs authorities are charged with the responsibility for policing a country's borders, and consequently they need to have in place measures to ensure that only legitimate trade takes place and that this trade does not present security concerns. On the other hand we have the requirements of traders, who benefit from an environment of trade facilitation with speedy and efficient movement of cargo across international borders, with minimal bureaucratic intervention. This paper focuses on and provides early discussion and comments on the possible ramifications of the introduction of the 24-hour rule in China, effective for all exports and imports of sea freight container traffic since January 1, 2009. The new rules will have significant impact on the logistics flows of exporters and importers alike. Specifically, the reporting requirements timelines are likely to result in increased costs in cargo processing at wharves that traders will have to bear; place added pressure on storage facilities at wharves, or at container depots; and may additionally increase the amount of inventory buffer because of the timing of the data reporting requirements. The paper concludes that security needs have prevailed over trade facilitation considerations and that traders should urgently implement a review of existing practices to ensure they comply with the China Customs requirements, whilst simultaneously minimizing cost increases. 展开更多
关键词 24-hour rule cargo security ANTI-TERRORISM international regulations China Customs
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Library open 24/7:A study of user needs and library management concerns
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作者 BAO Xueming 《Chinese Journal of Library and Information Science》 2009年第1期19-39,共21页
Facing competition from Web-based information service development, academic librarians need to find ways to attract more users to the physical library buildings. This study investigated user needs and library manageme... Facing competition from Web-based information service development, academic librarians need to find ways to attract more users to the physical library buildings. This study investigated user needs and library management concerns for a 24/7 service through two surveys: 1) User feedback survey at Seton Hall University Library, and 2) Survey of Academic Library Deans and Directors in the USA. Based on these two surveys, the paper not only discussed the current status of libraries open 24/7 in the USA and showed the demographics of users of the 24/7 service at Seton Hall University, it also stated reasons to use the 24/7 service. In addition, the paper revealed library management concerns of the24/7 service. Three implications, which have been guided by Scott Bennett's theory of learning commons for planning library space, were drawn from the findings in this paper. 展开更多
关键词 Academic library open 24/7 BUILDINGS Learning commons
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Statement by Dr Edward Van Roy Director,Social Development Division,ESCAP at the opening ceremony on 24 October 1995
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《开放教育研究》 1995年第1期43-44,共2页
Distinguished participants,ladies and grntlemen:It gives me great pleasure,on behalf of the United Nations Ecomomic and Social Commission for Asia and the Pacific, to join you today at
关键词 Statement by Dr Edward Van Roy Director Social Development Division ESCAP at the opening ceremony on 24 October 1995
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The lived experience of a 24-hour support center for persons with psychiatric disabilities: Making me feel almost like an ordinary person
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作者 Ann-Christin Janlov Irene Persson Agneta Berg 《Open Journal of Nursing》 2014年第1期42-50,共9页
This study illuminates nine psychiatric disabled persons’ lived experience of a newly established community-based service center open around the clock. This new 24-hour support center (SC) was established in 2011 in ... This study illuminates nine psychiatric disabled persons’ lived experience of a newly established community-based service center open around the clock. This new 24-hour support center (SC) was established in 2011 in a Swedish community to better match and facilitate the disabled persons’ needs. In order to illuminate the disabled person’s experiences individual interview was performed. A phenomenological-hermeneutical method inspired by Paul Ricoeur was used to interpret the texts. After a naive reading, a structural analysis revealed two themes: 1), becoming aware of myself as a person, and 2) having a lifeline and belongingness. The comprehensive understanding was interpreted as meaning “Making me feel almost like an ordinary person”, which incorporated the person’s past with their present together with a direction for the future and hope for a more fulfilling life. 展开更多
关键词 Psychiatric Disability Lived Experience Community Mental Health Service 24-hour Service Center Phenomenological-Hermeneutical Method Mental Health Nursing
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Esophageal manometry and 24-hour pH monitoring in esophagus surgery:28-year Chinese experience in a single center
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作者 邓波 《外科研究与新技术》 2011年第3期164-164,共1页
Objective To retrospectively review the experience of esophageal manometry and 24-hour pH monitoring in e-sophagus surgery. Methods From 1982 to 2010,patients with unspecific chest pain and undergone esophageal surger... Objective To retrospectively review the experience of esophageal manometry and 24-hour pH monitoring in e-sophagus surgery. Methods From 1982 to 2010,patients with unspecific chest pain and undergone esophageal surgery were received esophageal manometry and 24-hour pH monitoring. Results Among the patients with 展开更多
关键词 Esophageal manometry and 24-hour pH monitoring in esophagus surgery pH
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高眼压症原发性开角型青光眼及正常眼压性青光眼患者的24小时眼压分布规律
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作者 罗艳华 胡佩 +1 位作者 林斌武 欧扬 《山西医药杂志》 CAS 2023年第22期1697-1702,共6页
目的 通过24 h眼压监测探讨原发性开角型青光眼(POAG)、高眼压症(OHT)、及正常眼压性青光眼(NTG)眼压分布规律。方法 回顾性分析2019年1月至2021年1月期间于广东省中医院住院并完成24 h眼压监测的177例患者(354眼),根据24眼压监测结果... 目的 通过24 h眼压监测探讨原发性开角型青光眼(POAG)、高眼压症(OHT)、及正常眼压性青光眼(NTG)眼压分布规律。方法 回顾性分析2019年1月至2021年1月期间于广东省中医院住院并完成24 h眼压监测的177例患者(354眼),根据24眼压监测结果、角膜厚度、视神经OCT、视野及房角镜等检查结果,将患者分为对照组46例(92眼)、POAG组63例(126眼)、OHT组40例(80眼)及NTG组28例(56眼),进而统计分析不同组患者24 h眼压分布规律。结果 从眼压的峰值和谷值分布来看:(1)对照组和OHT组的眼压曲线有着类似的分布模式,眼压峰值集中在[6:00-8:00)这一时间段,而POAG组和NTG组也有着类似的分布模式,眼压峰值集中在[10:00-12:00);(2)4组患者的最低眼压分布相似,大部分集中分布在[20:00-4:00)这一时段。从眼压的波动来看:POAG组(10.1±3.7)mmHg和OHT组(11.1±3.5)mmHg的眼压波动要明显大于对照组(6.2±1.8)mmHg和NTG组(7.4±2.0)mmHg,且差异有统计学意义(P均<0.05,POAG与NTG P=0.001,OHT与NTG P<0.001),但POAG组和OHT组之间差异无统计学意义(P=0.154)。结论 眼压节律的改变可能也是青光眼发病机制中的重要一环。 展开更多
关键词 高眼压症 开角型青光眼 原发性 24小时眼压
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有无前列腺素类药物对眼压控制的原发性开角型青光眼患者24h眼压的影响 被引量:7
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作者 韩光杰 周和政 +1 位作者 张文强 陈云辉 《临床眼科杂志》 2015年第1期59-61,共3页
目的比较通过药物治疗眼压得到控制(峰压≤21 mm Hg)的原发性开角型青光眼(POAG)患者单用或联合应用前列腺素类(PGs)药物(有PGs组)和单用或联合应用其它降眼压药物(无PGs组)的24 h眼压测量结果。方法对经药物治疗后连续3个以上时间点测... 目的比较通过药物治疗眼压得到控制(峰压≤21 mm Hg)的原发性开角型青光眼(POAG)患者单用或联合应用前列腺素类(PGs)药物(有PGs组)和单用或联合应用其它降眼压药物(无PGs组)的24 h眼压测量结果。方法对经药物治疗后连续3个以上时间点测量的最高眼压值≤21 mm Hg的38例POAG患者(64只眼)于末次就诊的1周内进行24 h眼压测量,对比分析有PGs组(20例31只眼)和无PGs组(18例33只眼)的测量结果(波动幅度、眼压峰值和平均眼压)。结果有PGs组和无PGs组的24 h眼压波动幅度均值分别为(4.19±1.60)mm Hg、(5.63±1.71)mm Hg,差异有统计学意义(-3.479,P<0.01);两组的眼压峰值均数分别为(17.81±1.68)mm Hg、(18.79±1.41)mm Hg,差异有统计学意义(t=-2.537,P<0.05);有PGs组的平均眼压(15.89±1.68)mm Hg低于无PGs组(15.96±1.53)mm Hg,但差异无统计学意义(t=0.182,P>0.05)。结论通过药物治疗眼压得到控制的POAG患者中,尽管两组24 h眼压测量的平均眼压没有差别,但有PGs组的波动值和眼压峰值均低于无PGs组,提示PGs比其他药物对24 h眼压的控制效果更好。 展开更多
关键词 原发性开角型青光眼 前列腺素 24 h眼压
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新书文献中心24小时全天候开放——高校图书馆读者服务新尝试 被引量:2
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作者 刘玉梅 《图书馆建设》 CSSCI 北大核心 2009年第5期71-73,共3页
高校图书馆实行新书文献中心24小时全天候开放能够贯彻"读者第一,服务至上"的办馆宗旨,充分发挥图书馆的作用,增强信息的实效性,创立人性化服务原则,最大限度地满足读者的需求。但是,同时也存在一些问题,可以通过清理占座现... 高校图书馆实行新书文献中心24小时全天候开放能够贯彻"读者第一,服务至上"的办馆宗旨,充分发挥图书馆的作用,增强信息的实效性,创立人性化服务原则,最大限度地满足读者的需求。但是,同时也存在一些问题,可以通过清理占座现象、实现图书内部借还、控制图书复本数量、扩大借阅册数、延长借阅期限、加强宣传和导读工作等途径加以改进。 展开更多
关键词 新书文献中心 全天候开放 读者服务
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Dietary Surveys Carried out among Diabetic Patients Hospitalized in the Metabolic and Endocrine Diseases Department of the C.H.U-B
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作者 Lewis Raud Miamb Bertin Mikolo +2 位作者 Melyna Aïcha Ntsan Bonaventure Max Lazare Peneme Arnaud Wilfrid Etou Ossibi 《Journal of Biosciences and Medicines》 2024年第10期361-372,共12页
A varied and balanced diet has always been essential in the optimal management of diabetes. The objective of this work was to evaluate dietary surveys among 50 diabetic patients hospitalized in the metabolic and endoc... A varied and balanced diet has always been essential in the optimal management of diabetes. The objective of this work was to evaluate dietary surveys among 50 diabetic patients hospitalized in the metabolic and endocrine diseases department of the Brazzaville Hospital and University Center. This survey was carried out using two methods: dietary history and 24-hour recall. The results relating to the dietary history revealed in the patients a dietary imbalance characterized by snacking at meals, non-compliance with a balanced diet and a high frequency of consumption of foods rich in simple sugar. and saturated fats. Regarding the 24-hour recall, the survey showed that the average blood sugar levels of hospitalized patients increased depending on the number of meals. This meant that these hyperglycemias (2 to 5 g/L) observed in these patients exceeded three meals per day and required, among other things, an increase in insulin intake or doses. The age groups of diabetic patients were also divided. These age groups had partly defined the types of diabetes encountered. Regarding body mass index, women had a body mass index greater than 30 kg/m2 compared to men. This increase in body mass index was explained by being overweight or even obese due to excess body fat. 展开更多
关键词 Diabetes Dietary Survey Dietary History 24-hour Recall
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依据24h眼压峰值的青光眼个性化药物治疗观察 被引量:16
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作者 肖明 孙兴怀 +3 位作者 孟樊荣 房召彬 钱韶红 邱思羽 《中国眼耳鼻喉科杂志》 2012年第1期36-39,共4页
目的通过对开角型青光眼患者进行24h眼压监测后采用不同的降眼压用药时间,来探索青光眼的个性化治疗。方法入选18例正常眼压性青光眼和14例原发性开角型青光眼,治疗前均给予视野检查,进行24h眼压监测(每2h1次),并根据眼压波动曲线,给予... 目的通过对开角型青光眼患者进行24h眼压监测后采用不同的降眼压用药时间,来探索青光眼的个性化治疗。方法入选18例正常眼压性青光眼和14例原发性开角型青光眼,治疗前均给予视野检查,进行24h眼压监测(每2h1次),并根据眼压波动曲线,给予前列腺素类降眼压药,1次/d,用药时间为峰值眼压提前12h;1个月后复查24h眼压,随访(23.7±12.4)个月,记录随访终末期的视野。结果治疗前平均眼压(16.8±3.5)mm Hg(1mm Hg=0.133kPa),峰值眼压(20.8±4.6)mm Hg,谷值眼压(13.7±3.1)mm Hg,眼压波动值(7.1±2.4)mm Hg;治疗后平均眼压(13.2±2.6)mm Hg,峰值眼压(16.4±3.4)mm Hg,谷值眼压(10.7±2.3)mm Hg,眼压波动值(5.7±2.1)mm Hg。治疗前后平均眼压、峰值眼压、谷值眼压、眼压波动值的差异均具有统计学意义(P<0.0001)。治疗前视敏度(19.0±5.2)dB,视敏度缺损值(8.2±4.9)dB;治疗后视敏度(19.7±5.5)dB,视敏度缺损值(7.2±5.1)dB。结论通过依据24h眼压峰值来确定青光眼的用药及其用药时点的选择,以及青光眼随访过程中治疗药物的调整,是一种值得推广的青光眼个性化治疗模式。 展开更多
关键词 24小时眼压 峰值眼压 开角型青光眼 个性化药物治疗
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高眼压症及原发性开角型青光眼患者的24 h眼压波动规律 被引量:8
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作者 刘雯婷 沈念慈 +2 位作者 朱力 丁怡 武蓉 《中国眼耳鼻喉科杂志》 2020年第5期369-374,共6页
目的通过24 h眼压测量来深入分析对比高眼压症与原发性开角型青光眼(POAG)患者的眼压曲线特征。方法收集2016年1月~2019年3月在我科门诊诊断为高眼压症的患者52例(104眼)及POAG尚未接受降眼压治疗的患者38例(76眼)。入院后行24 h眼压检... 目的通过24 h眼压测量来深入分析对比高眼压症与原发性开角型青光眼(POAG)患者的眼压曲线特征。方法收集2016年1月~2019年3月在我科门诊诊断为高眼压症的患者52例(104眼)及POAG尚未接受降眼压治疗的患者38例(76眼)。入院后行24 h眼压检查,用非接触性眼压计从早9时起每隔2 h测量眼压1次,至次日7时结束。分析2组患者的平均眼压,峰值眼压及时间点,谷值眼压及时间点,昼夜眼压波动及双眼眼压压差值及其分布情况,比较2组眼压波动的异同点。结果104眼高眼压症患者的平均眼压为(18.73±1.71)mmHg(1 mmHg=0.133 kPa),平均峰值眼压为(22.36±2.40)mmHg,平均谷值眼压为(15.63±2.09)mmHg,平均昼夜眼压波动为(6.72±2.24)mmHg。76眼POAG患者的平均眼压为(20.65±2.53)mmHg,平均峰值眼压为(25.78±2.81)mmHg,平均谷值眼压为(17.45±2.54)mmHg,平均昼夜眼压波动为(8.34±2.37)mmHg。2组的峰值及谷值眼压值分布最多的时间点均为凌晨3时及夜晚21时,大部分患者的峰值眼压时间点在门诊时间之外。高眼压症组中昼夜眼压波动位于5~8 mmHg的占比最大,为54.81%(57/104),POAG组中昼夜眼压波动>8 mmHg的占比最大,为53.95%(41/76)。高眼压症组中,16例患者经24 h眼压检查后监测到眼压波动异常,占比为30.77%(16/52);POAG组中经24 h眼压检查后有29例患者可以监测到眼压波动异常,占比为76.32%(29/38)。结论24 h眼压监测中,POAG患者较高眼压症患者的平均眼压、峰值眼压、谷值眼压、昼夜眼压波动及双眼压差均有增加。对于24 h眼压发现眼压波动较大的高眼压症患者应在后续加强密切随访,而对于POAG患者24 h眼压监测可在治疗前提供眼压的基线水平,为后续治疗提供参考及评估依据,因此建议将24 h眼压作为高眼压症及POAG的常规检查手段。 展开更多
关键词 高眼压症 原发性开角型青光眼 24 h眼压测量 昼夜眼压波动
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24小时眼压监测中夜间眼压测量方法的探讨 被引量:13
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作者 房召彬 肖明 《中国眼耳鼻喉科杂志》 2011年第2期98-99,共2页
目的比较24h眼压监测中夜间即刻坐位眼压值和坐起休息10min后测得的眼压值,探讨夜间眼压的不同测量方法对青光眼24h眼压昼夜波动的影响。方法对已确诊且未用药、未做过手术的48例正常眼压性青光眼及17例原发性开角型青光眼患者进行24h... 目的比较24h眼压监测中夜间即刻坐位眼压值和坐起休息10min后测得的眼压值,探讨夜间眼压的不同测量方法对青光眼24h眼压昼夜波动的影响。方法对已确诊且未用药、未做过手术的48例正常眼压性青光眼及17例原发性开角型青光眼患者进行24h眼压监测,每2h1次,其中测量夜间0:00、2:00、4:00眼压时,逐个唤起患者后立即测,后嘱患者坐起休息10min再测,采用SPSS软件以配对t检验分析比较测量结果。结果夜间即刻坐位眼压值和坐起休息10min后测得的眼压值差异有统计学意义(P<0.001),正常眼压性青光眼与原发性开角型青光眼间眼压差值差异有统计学意义(P<0.05)。结论即刻坐位眼压值能更准确反映夜间眼压,对24h眼压测量及青光眼诊断及治疗更有价值,值得临床应用。 展开更多
关键词 24小时眼压 夜间眼压 正常眼压性青光眼 原发性开角型青光眼
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雄性不育和可育水稻开颖对茉莉酸甲酯响应的差异 被引量:42
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作者 宋平 夏凯 +4 位作者 吴传万 包冬萍 陈丽莉 周燮 曹显祖 《Acta Botanica Sinica》 CSCD 2001年第5期480-485,共6页
以水稻 (Oryzasativasubsp .indica)雄性不育系和可育系为材料 ,在室内用溶液浸已开过一天花的水稻离体穗 2min ,发现 4mmol/L茉莉酸甲酯 (MeJA)能显著诱导水稻开颖 ,且MeJA诱导水稻雄性不育材料开颖的效应明显强于可育材料 (如保持系... 以水稻 (Oryzasativasubsp .indica)雄性不育系和可育系为材料 ,在室内用溶液浸已开过一天花的水稻离体穗 2min ,发现 4mmol/L茉莉酸甲酯 (MeJA)能显著诱导水稻开颖 ,且MeJA诱导水稻雄性不育材料开颖的效应明显强于可育材料 (如保持系和常规品种 ) ,MeJA使雄性不育系珍汕 97A、温敏雄性核不育系培矮 6 4S的当天最后开颖率达到 40 %以上 ,保持系珍汕 97B、常规品种“培矮 6 4”的当天最后开颖率仅有 (2 1± 1.5 ) %、(2 5± 2 .1) % ,对照穗在当天始终不开颖或开颖极少 (<5 % ) ;不育系开颖对MeJA响应的滞后期比可育系短 10min左右。在田间 ,2mmol/LMeJA溶液浸或喷雾水稻连体穗 ,也同样能明显提高培矮 6 4S的开颖率 ;辅以人工授粉 ,MeJA能大幅度提高珍汕97A、龙特浦A的结实率 (提高 2 4%以上 )。 1mmol/L水杨酸 (SA)能抑制MeJA诱导水稻开颖 ,而MeJA的再次处理能解除SA对MeJA诱导雄性不育系开颖的抑制效应 ,SA抑制MeJA诱导保持系开颖的效应不能被再次使用MeJA所解除。 2 4_表油菜素内酯 (2 4_epiBL)预先处理能显著增强MeJA诱导不育系开颖 ,而对于保持系 ,此效应不明显。 展开更多
关键词 水稻 雄性不育系 保持系 开颖 茉莉酸甲酯 水杨酸 24-表油菜素内酯
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补中益气汤对阿霉素诱导的大鼠肾病的作用 被引量:3
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作者 郭继光 张海燕 +2 位作者 李朝鹏 高飒 李芸 《河北大学学报(自然科学版)》 CAS 北大核心 2015年第3期298-304,共7页
以阿霉素肾病大鼠模型为研究对象,采用了血液生化学和组织病理学方法,分析了补中益气汤对阿霉素肾病的作用和可能的机制.Wistar雄性大鼠60只,随机分为对照组(n=10)、模型组(n=10)、激素组(n=10)和补中益气汤低剂量组(n=10)、中剂量组(n=... 以阿霉素肾病大鼠模型为研究对象,采用了血液生化学和组织病理学方法,分析了补中益气汤对阿霉素肾病的作用和可能的机制.Wistar雄性大鼠60只,随机分为对照组(n=10)、模型组(n=10)、激素组(n=10)和补中益气汤低剂量组(n=10)、中剂量组(n=10)和高剂量组(n=10).采用阿霉素二次尾静脉注射法(首次6mg/kg,二次3mg/kg)制作阿霉素肾病的大鼠模型.在阿霉素注射后7,21,42d将大鼠置于代谢笼中分别收集24h尿液,测定24h尿蛋白.末次给药后,眼眶取血检测肾功能指标,包括肌肝SCR(serum creatine)和尿素氮BUN(blood urea nitrogen);处死大鼠并观察肾组织病理改变.结果表明:补中益气汤可以显著减少尿蛋白的排泄并缓解肾皮质上皮细胞的病理学改变.这提示补中益气汤对阿霉素大鼠能够通过改善尿蛋白的排泄,缓解肾脏病理改变,从而起到对肾脏的保护作用. 展开更多
关键词 阿霉素肾病 补中益气汤 24 h尿蛋白 肌酐 尿素氮 24-hour URINE protein (24 HUP)
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夜间血压下降对开角型青光眼视神经损伤的影响 被引量:2
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作者 赵炜 卢艳 《国际眼科杂志》 CAS 2012年第10期1869-1872,共4页
目的:探讨夜间血压下降与开角型青光眼和正常眼压性青光眼患者视神经损伤进展的关系。方法:对我院眼科门诊确诊的开角型青光眼和正常眼压性青光眼患者51例51眼分别进行视野、OCT检查,进行平均视神经纤维层厚度、24h动态血压监测、24h眼... 目的:探讨夜间血压下降与开角型青光眼和正常眼压性青光眼患者视神经损伤进展的关系。方法:对我院眼科门诊确诊的开角型青光眼和正常眼压性青光眼患者51例51眼分别进行视野、OCT检查,进行平均视神经纤维层厚度、24h动态血压监测、24h眼压监测等检查,分析夜间血压过度下降与视野进展率的关系。结果:根据夜间血压下降值(dip)进行分组,三组间有显著性差异的数值为平均缺损(MD)差值(P=0.032)、眼压峰值(P=0.003)、视野缺损计分差值(P=0.041)。在视野缺损进展组、视野缺损改善组、视野缺损不变组间,dip有显著性差异(P=0.028)。视野缺损进展组夜间血压下降值明显高于其他两组。夜间血压过度降低组视野缺损进展率明显高于不过度降低组(视野缺损进展率分别为50%,7%)。影响视神经纤维层(RNFL)厚度的相关因素为夜间最低平均动脉压和dip(P=0.011,P=0.032,R2=0.081);影响MD值的相关因素为眼压波动(P=0.026,R2=0.115);影响模式标准差(PSD)值的相关因素为眼压波动和dip(P=0.020,P=0.044,R2=0.141)。结论:与开角型青光眼相比,正常眼压性青光眼患者中夜间血压过度下降的发生率较高。夜间血压过度降低组中视野损伤进展明显。视野缺损进展组夜间血压降低更明显。眼压波动与dip是正常眼压性青光眼和高眼压开角型青光眼的患者视神经损伤与视野缺损高危因素。 展开更多
关键词 24H动态血压 视野 视神经纤维层 原发性开角型青光眼
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