The emergence of Y6-type nonfullerene acceptors has greatly enhanced the power conversion efficiency(PCE)of organic solar cells(OSCs).However,which structural feature is responsible for the excellent photovoltaic perf...The emergence of Y6-type nonfullerene acceptors has greatly enhanced the power conversion efficiency(PCE)of organic solar cells(OSCs).However,which structural feature is responsible for the excellent photovoltaic performance is still under debate.In this study,two Y6-like acceptors BDOTP-1 and BDOTP-2 were designed.Different from previous Y6-type acceptors featuring an A–D–Aʹ–D–A structure,BDOTP-1,and BDOTP-2 have no electron-deficient Aʹfragment in the core unit.Instead,there is an electron-rich dibenzodioxine fragment in the core.Although this modification leads to a marked change in the molecular dipole moment,electrostatic potential,frontier orbitals,and energy levels,BDOTP acceptors retain similar three-dimensional packing capability as Y6-type acceptors due to the similar banana-shaped molecular configuration.BDOTP acceptors show good performance in OSCs.High PCEs of up to 18.51%(certified 17.9%)are achieved.This study suggests that the banana-shaped configuration instead of the A–D–Aʹ–D–A structure is likely to be the determining factor in realizing high photovoltaic performance.展开更多
Ceramic cores are the key intermediate components of hollow blades for aero-engine.Conventional processes,such as hot-press molding and gel film casting,face difficulties in fabricating complex-structured ceramic core...Ceramic cores are the key intermediate components of hollow blades for aero-engine.Conventional processes,such as hot-press molding and gel film casting,face difficulties in fabricating complex-structured ceramic cores due to the complexity of moulds and long process cycles.Stereolithography 3D printing provides a new idea for the fabrication of complex-structured ceramic cores.The effect of sintering temperature on open porosity,bulk density,weight loss rate,shrinkage rate,flexural strength and microstructure of the Al_(2)O_(3)-based ceramic core doped with 10vol.%polysilazane(PSZ)was studied.The sintering mechanism of PSZ-reinforced ceramic cores was analyzed.Results show that the optimum sintering temperature of PSZ-reinforced ceramic cores is 1,450°C.At this temperature,the open porosity of the ceramic core is 36.60%,bulk density is 2.33 g·cm^(-3),weight loss rate is 22.11%,shrinkage rate along the X,Y,Z directions is 5.72%,5.01%,9.61%,respectively;the flexural strength is 28.794 MPa at 25°C and 13.649 MPa at 1,500°C.Properties of 3D printing PSZ-reinforced ceramic cores can meet the casting requirement of superalloy hollow blades,which is expected to promote the industrial application of 3D printing complex structure ceramic cores.展开更多
Background: As the population age structure gradually ages, more and more elderly people were found to have pulmonary nodules during physical examinations. Most elderly people had underlying diseases such as heart, lu...Background: As the population age structure gradually ages, more and more elderly people were found to have pulmonary nodules during physical examinations. Most elderly people had underlying diseases such as heart, lung, brain and blood vessels and cannot tolerate surgery. Computed tomography (CT)-guided percutaneous core needle biopsy (CNB) was the first choice for pathological diagnosis and subsequent targeted drugs, immune drugs or ablation treatment. CT-guided percutaneous CNB requires clinicians with rich CNB experience to ensure high CNB accuracy, but it was easy to cause complications such as pneumothorax and hemorrhage. Three-dimensional (3D) printing coplanar template (PCT) combined with CT-guided percutaneous pulmonary CNB biopsy has been used in clinical practice, but there was no prospective, randomized controlled study. Methods: Elderly patients with lung nodules admitted to the Department of Oncology of our hospital from January 2019 to January 2023 were selected. A total of 225 elderly patients were screened, and 30 patients were included after screening. They were randomly divided into experimental group (Group A: 30 cases) and control group (Group B: 30 cases). Group A was given 3D-PCT combined with CT-guided percutaneous pulmonary CNB biopsy, Group B underwent CT-guided percutaneous pulmonary CNB. The primary outcome measure of this study was the accuracy of diagnostic CNB, and the secondary outcome measures were CNB time, number of CNB needles, number of pathological tissues and complications. Results: The diagnostic accuracy of group A and group B was 96.67% and 76.67%, respectively (P = 0.026). There were statistical differences between group A and group B in average CNB time (P = 0.001), number of CNB (1 vs more than 1, P = 0.029), and pathological tissue obtained by CNB (3 vs 1, P = 0.040). There was no statistical difference in the incidence of pneumothorax and hemorrhage between the two groups (P > 0.05). Conclusions: 3D-PCT combined with CT-guided percutaneous CNB can improve the puncture accuracy of elderly patients, shorten the puncture time, reduce the number of punctures, and increase the amount of puncture pathological tissue, without increasing pneumothorax and hemorrhage complications. We look forward to verifying this in a phase III randomized controlled clinical study. .展开更多
The gene encoding the core and NS3 proteins of hepatitis C virus was amplified by PCR, respectirely. Two genes were fused and formed the recombinant plamid pHCV CN (Core+NS3) and pHCV NC (NS3+Core). The fused plasmid ...The gene encoding the core and NS3 proteins of hepatitis C virus was amplified by PCR, respectirely. Two genes were fused and formed the recombinant plamid pHCV CN (Core+NS3) and pHCV NC (NS3+Core). The fused plasmid were expressed in E.coli 06. The pHC CN plasmid expressed fussion protein was shown by a major band with a expected molecular weight about 68 kD on SDS PAGE. However, the pHCV NC plasmid expressed fussion protein was 66 kD in molecular weight. The results indicate that the pHCV NC fussion protein differs from the pHCV CN fussion protein in mulecular weight. It suggests that the fusion way is important for the structure of recombinant proteins.展开更多
Cored wires for electric arc spraying of Al/Al 2 O 3 MMC coatings were developed, with Al 2 O 3 powder as the core material and commercial aluminium strip as the retaining sheath. The bond strength, ...Cored wires for electric arc spraying of Al/Al 2 O 3 MMC coatings were developed, with Al 2 O 3 powder as the core material and commercial aluminium strip as the retaining sheath. The bond strength, Al 2 O 3 content, microstructure, micro-hardness and wear resistance of coatings produced by arc spraying of the cored wires were experimentally investigated and were compared with those of pure aluminum coating.展开更多
LaF3：Yb^3＋ , Er^＋ microcrystals were synthesized by a hydrothermal method, and then, the LaF3： Yb^3＋ , Er^＋ microcrystals were coated with silica. Phase identification of LaF3： Yb^3＋ , Er^＋ and LaF3： Yb^3＋ ...LaF3：Yb^3＋ , Er^＋ microcrystals were synthesized by a hydrothermal method, and then, the LaF3： Yb^3＋ , Er^＋ microcrystals were coated with silica. Phase identification of LaF3： Yb^3＋ , Er^＋ and LaF3： Yb^3＋ , Er^＋/SiO2 was performed via XRD. The TEM image showed that the size of LaF3： Yb^3＋ , Er^＋ was 150 nm and LaF3： Yb^3＋ , Er^＋/SiO2 presented clearly a core/shell structure with 20 nm shell thickness. The upconversion spectra of LaF3： Yb^3＋ , Er^＋ and LaF3： Yb^3＋ , Er^＋/SiO2 in solid state and in ethanol were studied with a 980 nm diode laser as the excitation source. The upconversion spectra showed that the silica shell had little effect on the properties of fluorescence of the LaF3：Yb^3＋ , Er^＋ microcrystals. At the same time, the green luminescence photo of LaF3： Yb3＋, Er3＋/SiO2 in the PBS buffer was obtained, which indicated that the LaF3： Yb^3＋ , Er^＋/SiO2 could be used in biological applications.展开更多
Herein, combining solverthermal route and electrodeposition, we grew unique hybrid nanosheet arrays consisting of Co_3O_4 nanosheet as a core, PPy as a shell. Benefiting from the PPy as conducting polymer improving an...Herein, combining solverthermal route and electrodeposition, we grew unique hybrid nanosheet arrays consisting of Co_3O_4 nanosheet as a core, PPy as a shell. Benefiting from the PPy as conducting polymer improving an electron transport rate as well as synergistic effects from such a core/shell structure, a hybrid electrode made of the Co_3O_4@PPy core/shell nanosheet arrays exhibits a large areal capacitance of 2.11 F cm-2at the current density of 2 m A cm^(-2), a *4-fold enhancement compared with the pristine Co_3O_4electrode; furthermore, this hybrid electrode also displays good rate capability(*65 % retention of the initial capacitance from 2 to 20 m A cm^(-2)) and superior cycling performance(*85.5 % capacitance retention after 5000 cycles). In addition, the equivalent series resistance value of the Co_3O_4@PPy hybrid electrode(0.238 X) is significantly lower than that of the pristine Co_3O_4electrode(0.319 X). These results imply that the Co_3O_4@PPy hybrid composites have a potential for fabricating next-generation energy storage and conversion devices.展开更多
基金the open research fund of the Songshan Lake Materials Laboratory(2021SLABFK02)the National Key Research and Development Program of China(2017YFA0206600)the National Natural Science Foundation of China(51922032 and 21961160720).
文摘The emergence of Y6-type nonfullerene acceptors has greatly enhanced the power conversion efficiency(PCE)of organic solar cells(OSCs).However,which structural feature is responsible for the excellent photovoltaic performance is still under debate.In this study,two Y6-like acceptors BDOTP-1 and BDOTP-2 were designed.Different from previous Y6-type acceptors featuring an A–D–Aʹ–D–A structure,BDOTP-1,and BDOTP-2 have no electron-deficient Aʹfragment in the core unit.Instead,there is an electron-rich dibenzodioxine fragment in the core.Although this modification leads to a marked change in the molecular dipole moment,electrostatic potential,frontier orbitals,and energy levels,BDOTP acceptors retain similar three-dimensional packing capability as Y6-type acceptors due to the similar banana-shaped molecular configuration.BDOTP acceptors show good performance in OSCs.High PCEs of up to 18.51%(certified 17.9%)are achieved.This study suggests that the banana-shaped configuration instead of the A–D–Aʹ–D–A structure is likely to be the determining factor in realizing high photovoltaic performance.
基金This work was financially supported by the National Natural Science Foundation of China(No.U22A20129)National Science and Technology Major Project(No.2017-VI-0002-0072)+2 种基金National Key Research and Development Program of China(No.2018YFB1106600)Fundamental Research Funds for the Central Universities(WK5290000003)Students'Innovation and Entrepreneurship Foundation of USTC(Nos.CY2022G10 and CY2022C24).
文摘Ceramic cores are the key intermediate components of hollow blades for aero-engine.Conventional processes,such as hot-press molding and gel film casting,face difficulties in fabricating complex-structured ceramic cores due to the complexity of moulds and long process cycles.Stereolithography 3D printing provides a new idea for the fabrication of complex-structured ceramic cores.The effect of sintering temperature on open porosity,bulk density,weight loss rate,shrinkage rate,flexural strength and microstructure of the Al_(2)O_(3)-based ceramic core doped with 10vol.%polysilazane(PSZ)was studied.The sintering mechanism of PSZ-reinforced ceramic cores was analyzed.Results show that the optimum sintering temperature of PSZ-reinforced ceramic cores is 1,450°C.At this temperature,the open porosity of the ceramic core is 36.60%,bulk density is 2.33 g·cm^(-3),weight loss rate is 22.11%,shrinkage rate along the X,Y,Z directions is 5.72%,5.01%,9.61%,respectively;the flexural strength is 28.794 MPa at 25°C and 13.649 MPa at 1,500°C.Properties of 3D printing PSZ-reinforced ceramic cores can meet the casting requirement of superalloy hollow blades,which is expected to promote the industrial application of 3D printing complex structure ceramic cores.
文摘Background: As the population age structure gradually ages, more and more elderly people were found to have pulmonary nodules during physical examinations. Most elderly people had underlying diseases such as heart, lung, brain and blood vessels and cannot tolerate surgery. Computed tomography (CT)-guided percutaneous core needle biopsy (CNB) was the first choice for pathological diagnosis and subsequent targeted drugs, immune drugs or ablation treatment. CT-guided percutaneous CNB requires clinicians with rich CNB experience to ensure high CNB accuracy, but it was easy to cause complications such as pneumothorax and hemorrhage. Three-dimensional (3D) printing coplanar template (PCT) combined with CT-guided percutaneous pulmonary CNB biopsy has been used in clinical practice, but there was no prospective, randomized controlled study. Methods: Elderly patients with lung nodules admitted to the Department of Oncology of our hospital from January 2019 to January 2023 were selected. A total of 225 elderly patients were screened, and 30 patients were included after screening. They were randomly divided into experimental group (Group A: 30 cases) and control group (Group B: 30 cases). Group A was given 3D-PCT combined with CT-guided percutaneous pulmonary CNB biopsy, Group B underwent CT-guided percutaneous pulmonary CNB. The primary outcome measure of this study was the accuracy of diagnostic CNB, and the secondary outcome measures were CNB time, number of CNB needles, number of pathological tissues and complications. Results: The diagnostic accuracy of group A and group B was 96.67% and 76.67%, respectively (P = 0.026). There were statistical differences between group A and group B in average CNB time (P = 0.001), number of CNB (1 vs more than 1, P = 0.029), and pathological tissue obtained by CNB (3 vs 1, P = 0.040). There was no statistical difference in the incidence of pneumothorax and hemorrhage between the two groups (P > 0.05). Conclusions: 3D-PCT combined with CT-guided percutaneous CNB can improve the puncture accuracy of elderly patients, shorten the puncture time, reduce the number of punctures, and increase the amount of puncture pathological tissue, without increasing pneumothorax and hemorrhage complications. We look forward to verifying this in a phase III randomized controlled clinical study. .
文摘The gene encoding the core and NS3 proteins of hepatitis C virus was amplified by PCR, respectirely. Two genes were fused and formed the recombinant plamid pHCV CN (Core+NS3) and pHCV NC (NS3+Core). The fused plasmid were expressed in E.coli 06. The pHC CN plasmid expressed fussion protein was shown by a major band with a expected molecular weight about 68 kD on SDS PAGE. However, the pHCV NC plasmid expressed fussion protein was 66 kD in molecular weight. The results indicate that the pHCV NC fussion protein differs from the pHCV CN fussion protein in mulecular weight. It suggests that the fusion way is important for the structure of recombinant proteins.
文摘Cored wires for electric arc spraying of Al/Al 2 O 3 MMC coatings were developed, with Al 2 O 3 powder as the core material and commercial aluminium strip as the retaining sheath. The bond strength, Al 2 O 3 content, microstructure, micro-hardness and wear resistance of coatings produced by arc spraying of the cored wires were experimentally investigated and were compared with those of pure aluminum coating.
基金Project supported by the National Natural Science Foundation of China (10474096 and 50672030)
文摘LaF3：Yb^3＋ , Er^＋ microcrystals were synthesized by a hydrothermal method, and then, the LaF3： Yb^3＋ , Er^＋ microcrystals were coated with silica. Phase identification of LaF3： Yb^3＋ , Er^＋ and LaF3： Yb^3＋ , Er^＋/SiO2 was performed via XRD. The TEM image showed that the size of LaF3： Yb^3＋ , Er^＋ was 150 nm and LaF3： Yb^3＋ , Er^＋/SiO2 presented clearly a core/shell structure with 20 nm shell thickness. The upconversion spectra of LaF3： Yb^3＋ , Er^＋ and LaF3： Yb^3＋ , Er^＋/SiO2 in solid state and in ethanol were studied with a 980 nm diode laser as the excitation source. The upconversion spectra showed that the silica shell had little effect on the properties of fluorescence of the LaF3：Yb^3＋ , Er^＋ microcrystals. At the same time, the green luminescence photo of LaF3： Yb3＋, Er3＋/SiO2 in the PBS buffer was obtained, which indicated that the LaF3： Yb^3＋ , Er^＋/SiO2 could be used in biological applications.
基金financially supported by the National Natural Science Foundation of China(Grant No.2117103551472049 and 51302035)+7 种基金the Key Grant Project of Chinese Ministry of Education(Grant No.313015)the PhD Programs Foundation of the Ministry of Education of China(Grant No.20110075110008 and20130075120001)the National 863 Program of China(Grant No.2013AA031903)the Science and Technology Commission of Shanghai Municipality(Grant No.13ZR1451200)the Fundamental Research Funds for the Central Universitiesthe Program Innovative Research Team in University(IRT1221)the Shanghai Leading Academic Discipline Project(Grant No.B603)the Program of Introducing Talents of Discipline to Universities(No.111-2-04)
文摘Herein, combining solverthermal route and electrodeposition, we grew unique hybrid nanosheet arrays consisting of Co_3O_4 nanosheet as a core, PPy as a shell. Benefiting from the PPy as conducting polymer improving an electron transport rate as well as synergistic effects from such a core/shell structure, a hybrid electrode made of the Co_3O_4@PPy core/shell nanosheet arrays exhibits a large areal capacitance of 2.11 F cm-2at the current density of 2 m A cm^(-2), a *4-fold enhancement compared with the pristine Co_3O_4electrode; furthermore, this hybrid electrode also displays good rate capability(*65 % retention of the initial capacitance from 2 to 20 m A cm^(-2)) and superior cycling performance(*85.5 % capacitance retention after 5000 cycles). In addition, the equivalent series resistance value of the Co_3O_4@PPy hybrid electrode(0.238 X) is significantly lower than that of the pristine Co_3O_4electrode(0.319 X). These results imply that the Co_3O_4@PPy hybrid composites have a potential for fabricating next-generation energy storage and conversion devices.
