A new oxazole compound, 1,4 bis(naphtho[1,2 d][1,3]oxazol 2 yl)benzene(BNOB) was synthesized and incorporated into a thin plasticized polymeric membrane for sensing Amrinon. The sensor exhibits a linear response t...A new oxazole compound, 1,4 bis(naphtho[1,2 d][1,3]oxazol 2 yl)benzene(BNOB) was synthesized and incorporated into a thin plasticized polymeric membrane for sensing Amrinon. The sensor exhibits a linear response to Amrinon in the range of 7 98×10 -7 —1 52×10 -4 mol/L at pH 3 28—4 04. The response mainly originates from the Primary Inner Filter Effect, which causes a decrease in the fluorescence intensity of the sensor membrane. The distinct advantages of the proposed sensor are of full reversibility, high sensitivity and selectivity as well as short response time(<1 min), indicating that the sensor can be used to monitor Amrinon in serum samples.展开更多
Three 2-{(3R, 7aS)-1, 1-disubstituted-tetrahydro-1H-pyrrolo [1,2-c][1,3]oxazol-3-yl} phenols have been synthesized from salicylaldehyde and amino alcohols derived from L-proline, and used as ligands hi enantioselectiv...Three 2-{(3R, 7aS)-1, 1-disubstituted-tetrahydro-1H-pyrrolo [1,2-c][1,3]oxazol-3-yl} phenols have been synthesized from salicylaldehyde and amino alcohols derived from L-proline, and used as ligands hi enantioselective addition of diethylzinc to aldehydes, the ee values of obtained secondary alcohols were found in the range of 0-90%.展开更多
文摘A new oxazole compound, 1,4 bis(naphtho[1,2 d][1,3]oxazol 2 yl)benzene(BNOB) was synthesized and incorporated into a thin plasticized polymeric membrane for sensing Amrinon. The sensor exhibits a linear response to Amrinon in the range of 7 98×10 -7 —1 52×10 -4 mol/L at pH 3 28—4 04. The response mainly originates from the Primary Inner Filter Effect, which causes a decrease in the fluorescence intensity of the sensor membrane. The distinct advantages of the proposed sensor are of full reversibility, high sensitivity and selectivity as well as short response time(<1 min), indicating that the sensor can be used to monitor Amrinon in serum samples.
基金Project supported by the Key Laboratory of Organic Syntheses,Jiangsu Province(No.T2109102).
文摘Three 2-{(3R, 7aS)-1, 1-disubstituted-tetrahydro-1H-pyrrolo [1,2-c][1,3]oxazol-3-yl} phenols have been synthesized from salicylaldehyde and amino alcohols derived from L-proline, and used as ligands hi enantioselective addition of diethylzinc to aldehydes, the ee values of obtained secondary alcohols were found in the range of 0-90%.
