SIMULATION OF 3-D DEFORMATION AND MATERIAL FLOW DURING ROLL FORGING PROCESS USING SYSTEM OF OVAL-ROUND GROOVE

Basing on the analysis of the traits of the roll forging process, a system-model of computer simulation has been established. Three-dimensional rigid-plastic FEM has been used for the simulation of the deformation process in the oval and round pass rolling, including the entering, rolling, and separating stages. The analysis was conducted using the Deform-3D ver.5.0 code. The important information concerned with the deformation area characteristic, material flow, and velocity field has been presented. Otherwise, the location of the neutral plane in the deformation area was shown clearly.

Constrained geometry analysis to resolve 3-D deformations from three ground-based radars

When multiple ground-based radars(GB-rads)are utilized together to resolve three-dimensional(3-D)deformations,the resolving accuracy is related with the measurement geometry constructed by these radars.This paper focuses on constrained geometry analysis to resolve 3-D deformations from three GB-rads.The geometric dilution of precision(GDOP)is utilized to evaluate 3-D deformation accuracy of a single target,and its theoretical equation is derived by building a simplified 3-D coordinate system.Then for a 3-D scene,its optimal accuracy problem is converted into determining the minimum value of an objective function with a boundary constraint.The genetic algorithm is utilized to solve this constrained optimization problem.Numerical simulations are made to validate the correctness of the theoretical analysis results.

High-accuracy 3-D deformation measurement method with an improved structured-light principle

In this paper,a high-accuracy 3-D deformation measurement(HADM)method with structured light is proposed and applied to wing deformation measurement in wind tunnel experiments.The present method employs an arbitrarily arranged fringe projector and a perpendicularly placed camera.The exact phase-height mapping using the phase differences of the projected sinusoidal fringe patterns,as well as the spatial distribution of the fringe,is accurately derived.It not only presents high feasibility but also reduces systemic uncertainties arising from deviations between the ideal model and the real-world conditions.Meanwhile,a dynamic boundary process algorithm is proposed to reduce the measurement uncertainty caused by fringe fracture near the object boundary.It is calibrated that a high accuracy with the average measurement uncertainty of 0.0237 mm is achieved,which is less than 0.01%of the side length of 25 cm of the field of view.In the wind tunnel experiments,the 3-D deformations of the elastic wing,particularly the key geometric parameters such as wing tip position,angle of attack,and dihedral angle,are well reconstructed to provide an in-depth explanation for the aerodynamic characteristics.

Rainfall-triggered waste dump instability analysis based on surface 3D deformation in physical model test

Landslide is the second largest natural disaster after earthquake. It is of significance to study the evolution laws and failure mechanism of landslides based on its surface 3D deformation information. Based on the rainfall-triggered waste dump instability model test, we studied the failure mechanisms of the waste dump by integrating surface deformation and internal slope stress and proposed novel parameters for identifying landslide stability. We developed a noncontact measurement device, which can obtain millimeter-level 3D deformation data for surface scene in physical model test;Then we developed the similar materials and established a test model for a waste dump. Based on the failure characteristics of slope surface, internal stress of slope body and displacement contours during the whole process, we divided the slope instability process in model test into four stages: rainfall infiltration and surface erosion, shallow sliding, deep sliding, and overall instability. Based on the obtained surface deformation data, we calculated the volume change during slope instability process and compared it with the point displacement on slope surface. The results showed that the volume change can not only reflect the slow-ultra acceleration process of slope failure, but also fully reflect the above four stages and reduce the fluctuations caused by random factors. Finally, this paper proposed two stability identification parameters: the volume change rate above the slip surface and the relative velocity of volume change rate. According to the calculation of these two parameters in model test, they can be used for study the deformation and failure mechanism of slope stability.

(1-3)-β-D葡聚糖联合降钙素原、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究

目的探讨(1-3)-β-D葡聚糖联合降钙素原(procalcitonin,PCT)、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究。方法回顾性选取我院2020年1月—2022年6月住院的120例艾滋病患者为研究对象。依据实验室结果,将其分为马尔尼菲篮状菌感染确诊组(血或组织液培育养出马尔尼菲篮状菌),简称A组(62例),及马尔尼菲篮状菌感染临床诊断组[根据临床症状、体征、血常规及(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞多指标诊断],简称B组(58例)。检测患者(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞的表达水平,采用受试者工作特征(receiver-operating characteristic,ROC)曲线下面积(area under the curve,AUC)评估上述指标联合检测对艾滋病患者感染马尔尼菲篮状菌的诊断效能。结果A组的(1-3)-β-D葡聚糖和PCT水平均高于B组,CD4^(+)T淋巴细胞个数低于B组(P<0.05);(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞联合检测的AUC为0.933,(1-3)-β-D葡聚糖单独检测的AUC是0.812,PCT单独检测的AUC为0.883,CD4^(+)T淋巴细胞单独检测的AUC是0.810,(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的AUC皆优于三项单独检测,表明(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的诊断价值皆优于单一指标诊断,且联合检测的特异度、约登指数分别为92.43%和0.580,均高于三项单独检测。结论(1-3)-β-D葡聚糖联合PCT和CD4^(+)T淋巴细胞多指标对艾滋病马尔尼菲篮状菌感染具有非常高的临床诊断价值,能够帮助医生分析出高危风险患者,及时制定治疗方案,同时也承担预后效果的判断依据,对治疗艾滋病马尔尼菲篮状菌感染具有非常重要的研究价值。

1例RHD-CE(3-7)-D基因重组与RHCE变异型患者的血清学与分子生物学分析

目的 研究分析1例Rh血型弱D、弱cE患者的血清学与分子生物学特征,为该类患者的临床安全输血提供实验依据。方法 采用微柱凝胶卡法对患者红细胞进行ABO、RhDCcEe抗原的鉴定,同时采用试管法进行血型复核,抗人球蛋白卡法筛查不规则抗体;采用PCR-SSP法对RhDCcEe(RhD、RhC、Rhc、RhE、Rhe)基因型进行检测;三代全长测序技术对RHD/RHCE基因序列进行测序分析。结果 微柱凝胶卡法鉴定ABO、RhD、RhCcEe血型抗原的结果为:A抗原(-)、B抗原(-)、RhD(1+)、RhC(4+)、Rhc(1+)、RhE(1+)、Rhe(4+)、对照孔(-);试管法ABO、RhD、RhCcEe抗原鉴定该患者表型为:A抗原(-)、B抗原(-)、RhD(w+)、RhC(4+)、Rhc(w+)、RhE(w+)、Rhe(4+),对照管(-);抗人球蛋白卡法筛查患者不规则抗体阴性;PCR-SSP法血型基因分型RhDCcEe结果:RhD(+)、RhC(+)、Rhc(+)、RhE(+)、Rhe(+);RHD/RHCE基因结果:RHD单倍体1为外显子1-10全缺失,而单倍体2为外显子RHD-CE基因重组融合,且确认其重组类型为RHD-CE(3-7)-D,起点在外显子2(g.20238-20312之间),终点在外显子8(g49184-50480之间),同时RHCE基因第6外显子存在新碱基点突变RHCE*cE(827C>A)。结论RHD-CE(3-7)-D基因重组融合与RHCE*cE(827C>A)新等位基因突变可能引起D、cE血型抗原弱表达,为临床安全输血提供了重要的实验数据支持。

Experimental Study on Full-Surface Buckling of Variable Curvature Cylindrical Shell Using Multi-camera 3D-DIC System

To achieve full-surface strain measurement of variable curvature objects,a 360°3D digital image correlation(DIC)system is proposed.The measurement system consists of four double-camera systems,which capture the object’s entire surface from multiple angles,enabling comprehensive full-surface measurement.To increase the stitching quality,a hierarchical coordinate matching method is proposed.Initially,a 3D rigid body calibration auxiliary block is employed to track motion trajectory,which enables preliminary matching of four 3D-DIC sub-systems.Subsequently,secondary precise matching is performed based on feature points on the test specimen’s surface.Through the hierarchical coordinate matching method,the local 3D coordinate systems of each double-camera system are unified into a global coordinate system,achieving 3D surface reconstruction of the variable curvature cylindrical shell,and error analysis is conducted on the results.Furthermore,axial compression buckling experiment is conducted to measure the displacement and strain fields on the cylindrical shell’s surface.The experimental results are compared with the finite element analysis,validating the accuracy and effectiveness of the proposed multi-camera 3D-DIC measuring system.

基于二萘并[2,3-B∶2′,3′-D]呋喃基团的高效窄发射蓝光OLED器件

高效率窄光谱蓝色有机电致发光器件(OLED)是柔性显示领域的研究重点之一。本文以二萘并[2,3-B∶2′,3′-D]呋喃为弱电子受体、N-(4-联苯基)-1-萘胺作为电子给体设计合成了一种D-A-D型蓝光分子DPF-NA,其在正己烷溶液中的发射峰位于441 nm。理论计算与光物理测试结果显示DPF-NA具有杂化局域电荷转移激发态(HLCT)特性,兼具局域态(LE)高发光效率与电荷转移态(CT)高激子利用率特征,在二氯甲烷溶液中的光致发光量子效率(PLQY)为81.2%。基于质量分数3%DPF-NA掺杂浓度的OLED器件电致发光(EL)峰位于455 nm,半峰宽(FWHM)仅为26 nm,CIE(x,y)坐标为(0.14,0.08),最大外量子效率(EQEmax)为6.76%。

New 4-imino-4H-Chromeno[2,3-d]Pyrimidin-3(5H)-Amine: Synthesis, Cytotoxic Effects on Tumoral Cell Lines and in Silico ADMET Properties

The synthesis of new 4-imino-4H-chromeno[2,3-d]pyrimidin-3(5H)-amine in four steps including one step under microwave dielectric heating is reported. The structural identity of the synthesized compounds was established according to their spectroscopic analysis, such as FT-IR, NMR and mass spectroscopy. These new compounds were tested for their antiproliferative activities on seven representative human tumoral cell lines (Huh7 D12, Caco2, MDA-MB231, MDA-MB468, HCT116, PC3 and MCF7) and also on fibroblasts. Among them, only the compounds 6c showed micromolar cytotoxic activity on tumor cell lines (1.8 50 50 > 25 μM). Finally, in silico ADMET studies ware performed to investigate the possibility of using of the identified compound 6c as potential anti-tumor compound.

血浆(1-3)-β-D葡聚糖诊断新生儿侵袭性真菌感染的价值

探讨在针对新生儿侵袭性真菌感染的诊断中使用血浆(1-3)-β-D葡聚糖能够产生的诊断效能。方法 选取2021年1月到2022年2月因为侵袭性真菌感染于医院寻求医疗干预的新生儿总共60例作为本次研究的一部分研究对象记为1组;另外选取60例健康婴儿作为2组;统计、对比两组患者的血浆(1-3)-β-D葡聚糖水平、CD4+T淋巴细胞数水平;整理PCR技术针对1组患者诊断结果,将其与血浆(1-3)-β-D葡聚糖诊断侵袭性真菌感染的诊断效能进行对比。结果 研究结果显示1组患者的血浆(1-3)-β-D葡聚糖水平、CD4+T淋巴细胞数水平较之于2组患者存在明显差异,1组患者血浆(1-3)-β-D葡聚糖水平更高,而CD4+T淋巴细胞数水平明显更低;P<0.05。在针对诊断效能的考察上,血浆(1-3)-β-D葡聚糖诊断效能和PCR诊断结果之间在灵敏度、特异度方面差异不大,P>0.05。结论 针对罹患侵袭性真菌感染的新生儿使用血浆(1-3)-β-D葡聚糖进行检查,一定程度上能够确保诊断结果的严谨程度,可使用。

血浆(1,3)-β-D葡聚糖检测在侵袭性真菌感染诊断中的价值分析

研究血浆(1,3)-β-D葡聚糖检测技术(G实验)应用于侵袭性真菌感染(IFI)诊断中的应用价值。方法 选择我院在2023年1月至2024年1月期间收治的100例高危型侵袭型真菌感染患者,应用MB-80微生物快速检测动态系统以及对应的试剂对患者的血浆(1,3)-β-D葡聚糖进行检测,分析真菌培养、G实验和联合检测结果;三种方法的诊断效能;三种方法的ROC曲线。结果 确诊IFI阳性共28例,阴性共72例;联合检测的诊断效能高于真菌培养或者G实验。联合检测面积高于单一检测。结论 在侵袭性真菌感染的诊断中,应用血浆(1,3)-β-D葡聚糖检测,诊断效能良好,在和传统真菌培养技术联合检测下,可进一步提升诊断效能。

The Deformation Analysis of the 3D Alignment Control Network Based on the Multiple Congruence Models

In the construction and maintenance of particle accelerators,all the accelerator elements should be installed in the same coordinate system,only in this way could the devices in the actual world be consistent with the design drawings.However,with the occurrence of the movements of the reinforced concrete cover plates at short notice or building deformations in the long term,the control points upon the engineering structure will be displaced,and the fitness between the subnetwork and the global control network may be irresponsible.Therefore,it is necessary to evaluate the deformations of the 3D alignment control network.Different from the extant investigations,in this paper,to characterize the deformations of the control network,all of the congruent models between the points measured in different epochs have been identified,and the congruence model with the most control points is considered as the primary or fundamental model,the remaining models are recognized as the additional ones.Furthermore,the discrepancies between the primary S-transformation parameters and the additional S-transformation parameters can reflect the relative movements of the additional congruence models.Both the iterative GCT method and the iterative combinatorial theory are proposed to detect multiple congruence models in the control network.Considering the actual work of the alignment,it is essential to identify the competitive models in the monitoring network,which can provide us a hint that,even the fitness between the subnetwork and the global control network is good,there are still deformations which may be ignored.The numerical experiments show that the suggested approaches can describe the deformation of the 3D alignment control network roundly.

Monitoring slope deformation using a 3-D laser image scanning system: a case study

An ILRIS-36D 3-D laser image scanning system was used to monitor the Anjialing strip mine slope on Pingshuo in Shanxi province. The basic working principles, performance indexes, features and data collection and processing methods are illus-trated. The point cloud results are analyzed in detail. The rescale range analysis method was used to analyze the deformation char-acteristics of the slope. The results show that the trend of slope displacement is stable and that the degree of landslide danger is low. This work indicates that 3-D laser image scanning can supply multi-parameter, high precision real time data over long distances. These data can be used to study the distortion of the slope quickly and accurately.

Present-day 3D deformation field of Northeast China,observed by GPS and leveling

A broad view of present-day 3D deformation field around the Northeast China region was derived from GPS and leveling observations. We draw the following conclusions： First, the Northeast China region moved towards northwest with an average velocity of 5 ram/a, with respect to South China. The entire Northeast China region was in a low strain state from the strain rate field. Second, we processed two periods of first- order leveling data in 1970s and 1990s, showing the vertical deformation of the Northeast China region is ＂uplift in western part and subsidence in eastern part＇

多路径误差对BDS-3变形监测精度的影响

为定量分析BDS-3观测值多路径误差对变形监测精度的影响,选取包含7个站点的某水利工程2022年共128 d的BDS-3监测数据,对监测站点周围树木裁剪树枝前后BDS-3观测值多路径误差、变形监测精度及二者的相关性进行研究。结果表明:1)多路径误差与BDS-3变形监测精度间存在强相关性,与其平面和高程精度的相关系数分别大于0.93和0.81;2)监测站点周围树枝裁剪后,使用B1I和B3I观测值的平均多路径误差从0.676 m、0.426 m降低至0.329 m、0.230 m,N、E、U方向的平均监测精度分别达0.9 mm、0.8 mm、1.7 mm和1.1 mm、1.0 mm、2.2 mm,较裁剪树枝前分别提高63%、69%、58%和52%、61%、48%;3)改变周围观测环境削弱多路径误差的影响后,使用B1I观测值的精度优于使用B3I观测值的精度,因此在BDS-3短基线变形监测的应用中推荐使用B1I观测值。

Parallel computing approach for efficient 3-D X-ray-simulated image reconstruction

Accurate 3-dimensional(3-D)reconstruction technology for nondestructive testing based on digital radiography(DR)is of great importance for alleviating the drawbacks of the existing computed tomography(CT)-based method.The commonly used Monte Carlo simulation method ensures well-performing imaging results for DR.However,for 3-D reconstruction,it is limited by its high time consumption.To solve this problem,this study proposes a parallel computing method to accelerate Monte Carlo simulation for projection images with a parallel interface and a specific DR application.The images are utilized for 3-D reconstruction of the test model.We verify the accuracy of parallel computing for DR and evaluate the performance of two parallel computing modes-multithreaded applications(G4-MT)and message-passing interfaces(G4-MPI)-by assessing parallel speedup and efficiency.This study explores the scalability of the hybrid G4-MPI and G4-MT modes.The results show that the two parallel computing modes can significantly reduce the Monte Carlo simulation time because the parallel speedup increment of Monte Carlo simulations can be considered linear growth,and the parallel efficiency is maintained at a high level.The hybrid mode has strong scalability,as the overall run time of the 180 simulations using 320 threads is 15.35 h with 10 billion particles emitted,and the parallel speedup can be up to 151.36.The 3-D reconstruction of the model is achieved based on the filtered back projection(FBP)algorithm using 180 projection images obtained with the hybrid G4-MPI and G4-MT.The quality of the reconstructed sliced images is satisfactory because the images can reflect the internal structure of the test model.This method is applied to a complex model,and the quality of the reconstructed images is evaluated.

血清25-羟维生素-D3 超敏C反应蛋白及心电图参数与ST段抬高型心肌梗死患者介入治疗后发生恶性心律失常的关系

目的:探讨血清25-羟维生素-D3(25-hydroxyvitamin D3,25-(OH)-D3)、超敏C反应蛋白(High sensitivity C-reactive protein,hs-CRP)、心电图参数变化与ST段抬高型心肌梗死(ST segment elevation myocardial infarction,STEMI)患者经皮冠脉介入术(Percutaneous coronary intervention,PCI)后发生恶性心律失常的关系。方法:选取我院2020年1月至2022年6月实施PCI治疗的193例STEMI患者作为研究对象,根据患者术后72h内是否发生恶性心律失常分为心律失常组38例、对照组155例,对比两组患者入院12h内的25-(OH)-D3、hs-CRP、血清电解质、血常规指标、血脂指标、心肌酶学指标,并对患者PCI术后实施连续动态心电图监测,对比两组患者心电图碎裂QRS波、校正Tp-e间期(Corrected Tp-e interval,Tp-ec)、QT离散度(QT dispersion,Qtd),并采用Logistic回归模型分析上述指标与STEMI患者PCI术后发生恶性心律失常的关系。结果:心律失常组患者的血清25-(OH)-D3水平低于对照组,心律失常组患者的血清hs-CRP、Tp-ec测定值、Qtd测定值、碎裂QRS波检出率均高于对照组,上述指标组间差异均具有统计学意义(P<0.05);心律失常组患者的白细胞(White blood cell,WBC)、肌钙蛋白I(Troponin I,cTnI)、肌酸激酶同工酶(Creatine kinase isoenzyme,CK-MB)、肌红蛋白(Myoglobin,MYO)、K+、Mg 2+水平均高于对照组患者,差异具有统计学意义(P<0.05);Logistic回归模型结果显示:cTnI、CK-MB、K+、hs-CRP、Tp-ec、Qtd增高,碎裂QRS波阳性会显著增大STEMI患者PCI后发生恶性心律失常的风险(P<0.05);血清25-(OH)-D3水平增高会降低STEMI患者PCI后发生恶性心律失常的风险(P<0.05)。结论:STEMI患者血清25-(OH)-D3水平降低、hs-CRP增高、PCI术后Tp-ec、Qtd增高、出现碎裂QRS波会增大患者出现恶性心律失常的风险。

Fe_(3)O_(4)/BiOBr/BiOI的制备及降解2,4-D的性能研究

采用水热法制备了微米球花状结构的Fe_(3)O_(4)/BiOBr/BiOI复合材料,通过SEM、XRD、XPS和UV-Vis等手段对催化剂进行表征分析。结果表明,该催化剂对2,4-D具有高效的光降解性能和光催化效率(80 min,88%)。降解速率常数为2.498×10^(-2)min^(-1),分别是Br∶I=5∶5(K=2.004×10^(-2)min^(-1))、BiOBr(K=1.289×10^(-2)min^(-1))和BiOI(K=6.98×10-3min-1)的1.25倍、1.94倍与3.58倍。这是由于Fe_(3)O_(4)/BiOBr/BiOI复合材料内部形成了异质结,利于光生载流子的分离。此外,5次循环实验后,降解效率保持在82.9%,证明该催化剂稳定、可回收、可磁分离。

9Cr3W3Co耐热钢锻造工艺数值模拟及实验研究

通过Deform 3D模拟了9Cr3W3Co耐热钢连续多道次锻造工艺,分析了等效应力、等效应变场和温度场的分布规律。基于模拟结果,优化了锻造工艺,并通过Gleeble-3800热模拟试验机对9Cr3W3Co耐热钢进行不同变形参数多道次热压缩实验,分析了不同变形参数下的热变形行为,结合热模拟真应力-真应变曲线和显微组织,验证了模拟的准确性。结果表明,模拟后的优化锻造工艺为应变速率5 s^(-1),变形方式为先大变形后小变形,变形后的坯料心部温度分布均匀,为951~970℃,等效应变分布均匀,为2.15~2.19。当应变速率为5 s^(-1)时,动态再结晶晶粒尺寸随变形温度的升高而变大,采用先大压下量后小压下量的方式,可获得完全再结晶的等轴晶,平均晶粒尺寸为15μm,变形后组织均匀性更好。结合微观组织演变结果分析,模拟实验具有可行性,实验结果与模拟结果基本吻合。

室温下β⁃Ga_(2)O_(3)纳米柱的脆韧转变研究

β⁃Ga_(2)O_(3)的力学性能关系到相关电子器件的制造、封装以及应用,然而目前关于β⁃Ga_(2)O_(3)单晶的力学变形机制研究还相对匮乏。本文研究了(100)β⁃Ga_(2)O_(3)单晶在压应力作用下的力学行为,发现其极易沿着(100)B面脆断,并计算得到该材料的断裂应力范围为3141~6151 MPa。进一步揭示了不同长径比、不同直径对β⁃Ga_(2)O_(3)纳米柱力学变形行为的影响,实验结果表明:当长径比>2时,β⁃Ga_(2)O_(3)纳米柱在不同直径下均沿着(100)B面发生脆断;当长径比<2且直径<200 nm时,(100)β⁃Ga_(2)O_(3)发生脆性向塑性的转变,表现为先沿着(201)面发生滑移,之后沿着(100)B面断裂。最后,讨论了晶体学取向对于小尺寸β⁃Ga_(2)O_(3)塑性的影响,研究结果为理解β⁃Ga_(2)O_(3)的力学性能提供借鉴。