Third-order nonlinear optical (NLO) materials have broad application prospects in high-density data storage, optical computer, modern laser technology, and other high-tech industries. The structures and frequencies of...Third-order nonlinear optical (NLO) materials have broad application prospects in high-density data storage, optical computer, modern laser technology, and other high-tech industries. The structures and frequencies of Dinaphtho[2,3-b:2’,3’-d]thiophene-5,7,12,13-tetraone (DNTTRA) and its 36 derivatives containing azobenzene were calculated by using density functional theory B3LYP and M06-2X methods at 6-311++g(d, p) level, respectively. Besides, the atomic charges of natural bond orbitals (NBO) were analyzed. The frontier orbitals and electron absorption spectra of A-G5 molecule were calculated by TD-DFT (TD-B3LYP/6-311++g(d, p) and TD-M06-2X/6-311++g(d, p)). The NLO properties were calculated by effective finite field FF method and self-compiled program. The results show that 36 molecules of these six series are D-π-A-π-D structures. The third-order NLO coefficients γ (second-order hyperpolarizability) of the D series molecules are the largest among the six series, reaching 10<sup>7</sup> atomic units (10<sup><span style="color:#4F4F4F;font-family:-apple-system, " font-size:14px;white-space:normal;background-color:#ffffff;"="">-</span>33</sup> esu) of order of magnitude, showing good third-order NLO properties. Last, the third-order NLO properties of the azobenzene ring can be improved by introducing strong electron donor groups (e.g. -N(CH<sub>3</sub>)<sub>2</sub> or -NHCH<sub>3</sub>) in the azobenzene ring, so that the third-order NLO materials with good performance can be obtained.展开更多
Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneuro...Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneurons innervating differe nt muscles is limited.In this study,we investigated the spatial distribution and relative position of different motoneurons that control the deep muscles of the mouse hindlimbs,which were innervated by the obturator nerve,femoral nerve,inferior gluteal nerve,deep pe roneal nerve,and tibial nerve.Locations were visualized by combining a multiplex retrograde tracking technique compatible with three-dimensional imaging of solvent-cleared o rgans(3DISCO)and 3-D imaging technology based on lightsheet fluorescence microscopy(LSFM).Additionally,we propose the hypothesis that"messenger zones"exist as interlaced areas between the motoneuron pools that dominate the synergistic or antagonist muscle groups.We hypothesize that these interlaced neurons may participate in muscle coordination as messenger neurons.Analysis revealed the precise mutual positional relationships among the many motoneurons that innervate different deep muscles of the mouse.Not only do these findings update and supplement our knowledge regarding the overall spatial layout of spinal motoneurons that control mouse limb muscles,but they also provide insights into the mechanisms through which muscle activity is coordinated and the architecture of motor circuits.展开更多
In this work,a hybrid integrated optical transmitter module was designed and fabricated.A proton-exchanged Mach–Zehnder lithium niobate(LiNbO_(3))modulator chip was chosen to enhance the output extinction ratio.A fib...In this work,a hybrid integrated optical transmitter module was designed and fabricated.A proton-exchanged Mach–Zehnder lithium niobate(LiNbO_(3))modulator chip was chosen to enhance the output extinction ratio.A fiber was used to adjust the rotation of the polarization direction caused by the optical isolator.The whole optical path structure,including the laser chip,lens,fiber,and modulator chip,was simulated to achieve high optical output efficiency.After a series of process improvements,a module with an output extinction ratio of 34 dB and a bandwidth of 20.5 GHz(from 2 GHz)was obtained.The optical output efficiency of the whole module reached approximately 21%.The link performance of the module was also measured.展开更多
The technique of phase measuring profilometry using a single phase step method is proposed.This method can automatically obtain phase value at each pixel by using a discret cosine transform algorithm.The method is abl...The technique of phase measuring profilometry using a single phase step method is proposed.This method can automatically obtain phase value at each pixel by using a discret cosine transform algorithm.The method is able to automatically recognize any position between depression and elevation on an object surface.Theoretical analysis and experimental verification are presented.展开更多
AIM:To present the outcome of modified grid laser photocoagulation(GLP)in diffuse diabetic macular edema(DDME)in eyes without extrafoveal and/or vitreofoveal traction.METHODS:Inclusion criteria for the retrospective s...AIM:To present the outcome of modified grid laser photocoagulation(GLP)in diffuse diabetic macular edema(DDME)in eyes without extrafoveal and/or vitreofoveal traction.METHODS:Inclusion criteria for the retrospective study were DDME eyes of patients with typeⅡdiabetes mellitus that had≥4 months of follow-up following GLP.Only one eye per patient was analyzed.Using 3-D spectral-domain optical coherence tomography(3-D SDOCT),eyes that had either extrafoveal or vitreofoveal traction,or had been previously treated by an intravitreal medication(s)were excluded.Treated DDME eyes were divided into 4 groups:A)"Classic"DDME that involved the central macula;B)edema did not involve the macular center;C)eyes associated with central epiretinal membrane(ERM);D)DDME that was associated with macular capillary dropout≥2 disc-diameter(DD).RESULTS:GLP outcome in 35 DDME eyes after 4-24(mean,13.1±6.9)months was as follows:Group A)18eyes with"classic"DDME.Following one or 2(mean,1.2)GLP treatments,best-corrected visual acuity(BCVA)improved by 1-2 Snellen lines in 44.4%(8/18)of eyes,and worsened by 1 line in 11.1%(2/18).Central macular thickness(CMT)improved by 7%-49%(mean,26.6%)in77.8%(14/18)of eyes.Causes of CMT worsening(n=4)were commonly explainable,predominantly(n=3)associated with emergence of extrafoveal traction,5-9months post-GLP.Group B)GLP(s)in DDME that did not involve the macular center(n=6)resulted in improved BCVA by 1-2 lines in 2 eyes.However,the central macula became involved in the edema process after the GLP in 3(50%)eyes,associated with an emergence of extrafoveal traction in one of these eyes 4months following the GLP.Group C)GLP failed in all 5eyes associated with central ERM.Group D)GLP was of partial benefit in 2 of 6 treated eyes with macular capillary dropout≥2DD.CONCLUSION:Eyes with DDME that involved the macular center were found to achieve favourable outcomes after GLP(s)during mid-term follow-up,unless complicated pre-GLP or post-GLP by vltreoretinal interface abnormalities,often extrafoveal traction or ERM,or by capillary dropout≥2DD.Prospective studies with larger cohorts are required.展开更多
In recent years, with the level of science and technology progress, largely to promote the development of animation techniques. Animated film is divided into two-dimensional animation and three-dimensional animation, ...In recent years, with the level of science and technology progress, largely to promote the development of animation techniques. Animated film is divided into two-dimensional animation and three-dimensional animation, both in the retention feature animated films, based on the performance of each with different strengths, thus forming a different artistic style. Wherein the two-dimensional animation is the most common one is the most basic form of expression in animation technology is relatively mature and complete, but because of the development of animation techniques, two-dimensional animation can not meet the needs of the audience. Thus, the effective combination of two-dimensional animation and three-dimensional animation technology, the advantages of integration between the two is particularly important, so that innovation in the form of screen performance, enhance audio-visual experience. In this paper, two-dimensional animation and three-dimensional animation skills fusion analysis and research, and put forward a number of specific observations, in order to learn.展开更多
The present work deals with 12-bit Nyquist current-steering CMOS digital-to-analog converter (DAC) which is an essential part in baseband section of wireless transmitter circuits. Using oversampling ratio (OSR) for th...The present work deals with 12-bit Nyquist current-steering CMOS digital-to-analog converter (DAC) which is an essential part in baseband section of wireless transmitter circuits. Using oversampling ratio (OSR) for the proposed DAC leads to avoid use of an active analog reconstruction filter. The optimum segmentation (75%) has been used to get the best DNL and reduce glitch energy. This segmentation ratio guarantees the monotonicity. Higher performance is achieved using a new 3-D thermometer decoding method which reduces the area, power consumption and the number of control signals of the digital section. Using two digital channels in parallel, helps reach 1-GSample/s frequency. Simulation results show that the spurious- free-dynamic-range (SFDR) in Nyquist rate is better than 64 dB for sampling frequency up to 1-GSample/s. The analog voltage supply is 3.3 V while the digital part of the chip operates with only 2.4 V. Total power consumption in Nyquist rate measurement is 144.9 mW. The chip has been processed in a standard 0.35 μm CMOS technology. Active area of chip is 1.37 mm2.展开更多
INTRODUCTION The level of man-made CO_(2) emissions worldwide climbed to a new record of 30 billion tons in 2010.In 2011,at the COP17 U.N.Climate Change Conference in Durban,South Africa,high-ranking representatives f...INTRODUCTION The level of man-made CO_(2) emissions worldwide climbed to a new record of 30 billion tons in 2010.In 2011,at the COP17 U.N.Climate Change Conference in Durban,South Africa,high-ranking representatives from around the world met again to discuss solutions.For the building sector,numerous energy-efficiency market changes and benchmarking resolutions,like the mandatory E.U.“nearly Net-Zero-Energy-Building(NET-ZEB’s)2018 and 2020 regulations”for all new public and privately owned buildings are now set up to help minimizing carbon emissions and reverse the negative impact.1 In the United States,the American Institute of Architects(AIA)adopted the 2030 Challenge as a voluntary program,where participating buildings aim to achieve a 90%fossil fuel reduction by 2025,and carbon-neutrality by 2030.2 To accomplish these energy goals,designers must strive to best design and utilize the resources available on a site.However,are these goals of achieving carbon-neutral buildings possible?How can NET-ZEB’s become the curricular standard and practical routine in education and the profession?To date,the basic curricular design process components with integrated project delivery metrics for a robust 3-D/4-D-net-zero regulatory design framework are either incomplete or missing,However,formally-based curriculums have begun to weave carbon-neutral design tools into their pedagogy.This research paper critically compares how these new criteria for digital 3-D-building information modeling(BIM),and“Integrated Project Delivery”are mandating a better integration of collaborative carbon-neutral designs into the curriculum and practice of the profession.The majority of those in architectural academia have been using generative computation primarily for pure,aesthetic form-finding,without applying zero-carbon-energy-driven global performance metrics and CO_(2)e reduction strategies to reiterate derived carbon-neutral designs.The advantage of 3-D-parametric design is that it links variables,dimensions,and materials to geometry in a way that when an input or simulation value changes,the 3-D/4-D model automatically updates all life-cycle scenarios and components simultaneously.展开更多
This paper introduces a new technique of fast acquiring 3D information in microscope based on integral imaging. Experimental results prove that the proposed method has advantageous properties including simple configur...This paper introduces a new technique of fast acquiring 3D information in microscope based on integral imaging. Experimental results prove that the proposed method has advantageous properties including simple configuration, no requirement of coherent light source and real-time 3D imaging information acquisition. This technique has an important prospect on optical microscopy and 3D display.展开更多
An iterative procedure is proposed for the variational analysis of Ti:LiNbO3 optical waveguides. A trial solution for the dominant electric field profile of arbitrary-order eigenmodes in strip waveguides and two coupl...An iterative procedure is proposed for the variational analysis of Ti:LiNbO3 optical waveguides. A trial solution for the dominant electric field profile of arbitrary-order eigenmodes in strip waveguides and two coupled waveguides is proposed and its parameters are determined using the variational method. The results calculated using this method agree well with those obtained using the finite-element method. The present method has been used to check the accuracy of the effective index method as well as a quasi-analytical technique based on the effective index method. The results show that the effective index method is generally accurate for the fundamental mode and becomes less accurate for higher-order vertical modes.展开更多
文摘Third-order nonlinear optical (NLO) materials have broad application prospects in high-density data storage, optical computer, modern laser technology, and other high-tech industries. The structures and frequencies of Dinaphtho[2,3-b:2’,3’-d]thiophene-5,7,12,13-tetraone (DNTTRA) and its 36 derivatives containing azobenzene were calculated by using density functional theory B3LYP and M06-2X methods at 6-311++g(d, p) level, respectively. Besides, the atomic charges of natural bond orbitals (NBO) were analyzed. The frontier orbitals and electron absorption spectra of A-G5 molecule were calculated by TD-DFT (TD-B3LYP/6-311++g(d, p) and TD-M06-2X/6-311++g(d, p)). The NLO properties were calculated by effective finite field FF method and self-compiled program. The results show that 36 molecules of these six series are D-π-A-π-D structures. The third-order NLO coefficients γ (second-order hyperpolarizability) of the D series molecules are the largest among the six series, reaching 10<sup>7</sup> atomic units (10<sup><span style="color:#4F4F4F;font-family:-apple-system, " font-size:14px;white-space:normal;background-color:#ffffff;"="">-</span>33</sup> esu) of order of magnitude, showing good third-order NLO properties. Last, the third-order NLO properties of the azobenzene ring can be improved by introducing strong electron donor groups (e.g. -N(CH<sub>3</sub>)<sub>2</sub> or -NHCH<sub>3</sub>) in the azobenzene ring, so that the third-order NLO materials with good performance can be obtained.
基金supported by the Chinese National General Program of the National Natural Science Foundation of China,No.82072162(to XY)。
文摘Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneurons innervating differe nt muscles is limited.In this study,we investigated the spatial distribution and relative position of different motoneurons that control the deep muscles of the mouse hindlimbs,which were innervated by the obturator nerve,femoral nerve,inferior gluteal nerve,deep pe roneal nerve,and tibial nerve.Locations were visualized by combining a multiplex retrograde tracking technique compatible with three-dimensional imaging of solvent-cleared o rgans(3DISCO)and 3-D imaging technology based on lightsheet fluorescence microscopy(LSFM).Additionally,we propose the hypothesis that"messenger zones"exist as interlaced areas between the motoneuron pools that dominate the synergistic or antagonist muscle groups.We hypothesize that these interlaced neurons may participate in muscle coordination as messenger neurons.Analysis revealed the precise mutual positional relationships among the many motoneurons that innervate different deep muscles of the mouse.Not only do these findings update and supplement our knowledge regarding the overall spatial layout of spinal motoneurons that control mouse limb muscles,but they also provide insights into the mechanisms through which muscle activity is coordinated and the architecture of motor circuits.
基金This work was supported by National Key Research and Development Program of China(2018YFB2201101)the Strategic Priority Research Program of Chinese Academy of Sciences,Grant No.XDB43000000Beijing Municipal Science&Technology Commission,Administrative Commission of Zhongguancun Science Park No.Z201100004020004。
文摘In this work,a hybrid integrated optical transmitter module was designed and fabricated.A proton-exchanged Mach–Zehnder lithium niobate(LiNbO_(3))modulator chip was chosen to enhance the output extinction ratio.A fiber was used to adjust the rotation of the polarization direction caused by the optical isolator.The whole optical path structure,including the laser chip,lens,fiber,and modulator chip,was simulated to achieve high optical output efficiency.After a series of process improvements,a module with an output extinction ratio of 34 dB and a bandwidth of 20.5 GHz(from 2 GHz)was obtained.The optical output efficiency of the whole module reached approximately 21%.The link performance of the module was also measured.
文摘The technique of phase measuring profilometry using a single phase step method is proposed.This method can automatically obtain phase value at each pixel by using a discret cosine transform algorithm.The method is able to automatically recognize any position between depression and elevation on an object surface.Theoretical analysis and experimental verification are presented.
文摘AIM:To present the outcome of modified grid laser photocoagulation(GLP)in diffuse diabetic macular edema(DDME)in eyes without extrafoveal and/or vitreofoveal traction.METHODS:Inclusion criteria for the retrospective study were DDME eyes of patients with typeⅡdiabetes mellitus that had≥4 months of follow-up following GLP.Only one eye per patient was analyzed.Using 3-D spectral-domain optical coherence tomography(3-D SDOCT),eyes that had either extrafoveal or vitreofoveal traction,or had been previously treated by an intravitreal medication(s)were excluded.Treated DDME eyes were divided into 4 groups:A)"Classic"DDME that involved the central macula;B)edema did not involve the macular center;C)eyes associated with central epiretinal membrane(ERM);D)DDME that was associated with macular capillary dropout≥2 disc-diameter(DD).RESULTS:GLP outcome in 35 DDME eyes after 4-24(mean,13.1±6.9)months was as follows:Group A)18eyes with"classic"DDME.Following one or 2(mean,1.2)GLP treatments,best-corrected visual acuity(BCVA)improved by 1-2 Snellen lines in 44.4%(8/18)of eyes,and worsened by 1 line in 11.1%(2/18).Central macular thickness(CMT)improved by 7%-49%(mean,26.6%)in77.8%(14/18)of eyes.Causes of CMT worsening(n=4)were commonly explainable,predominantly(n=3)associated with emergence of extrafoveal traction,5-9months post-GLP.Group B)GLP(s)in DDME that did not involve the macular center(n=6)resulted in improved BCVA by 1-2 lines in 2 eyes.However,the central macula became involved in the edema process after the GLP in 3(50%)eyes,associated with an emergence of extrafoveal traction in one of these eyes 4months following the GLP.Group C)GLP failed in all 5eyes associated with central ERM.Group D)GLP was of partial benefit in 2 of 6 treated eyes with macular capillary dropout≥2DD.CONCLUSION:Eyes with DDME that involved the macular center were found to achieve favourable outcomes after GLP(s)during mid-term follow-up,unless complicated pre-GLP or post-GLP by vltreoretinal interface abnormalities,often extrafoveal traction or ERM,or by capillary dropout≥2DD.Prospective studies with larger cohorts are required.
文摘In recent years, with the level of science and technology progress, largely to promote the development of animation techniques. Animated film is divided into two-dimensional animation and three-dimensional animation, both in the retention feature animated films, based on the performance of each with different strengths, thus forming a different artistic style. Wherein the two-dimensional animation is the most common one is the most basic form of expression in animation technology is relatively mature and complete, but because of the development of animation techniques, two-dimensional animation can not meet the needs of the audience. Thus, the effective combination of two-dimensional animation and three-dimensional animation technology, the advantages of integration between the two is particularly important, so that innovation in the form of screen performance, enhance audio-visual experience. In this paper, two-dimensional animation and three-dimensional animation skills fusion analysis and research, and put forward a number of specific observations, in order to learn.
文摘The present work deals with 12-bit Nyquist current-steering CMOS digital-to-analog converter (DAC) which is an essential part in baseband section of wireless transmitter circuits. Using oversampling ratio (OSR) for the proposed DAC leads to avoid use of an active analog reconstruction filter. The optimum segmentation (75%) has been used to get the best DNL and reduce glitch energy. This segmentation ratio guarantees the monotonicity. Higher performance is achieved using a new 3-D thermometer decoding method which reduces the area, power consumption and the number of control signals of the digital section. Using two digital channels in parallel, helps reach 1-GSample/s frequency. Simulation results show that the spurious- free-dynamic-range (SFDR) in Nyquist rate is better than 64 dB for sampling frequency up to 1-GSample/s. The analog voltage supply is 3.3 V while the digital part of the chip operates with only 2.4 V. Total power consumption in Nyquist rate measurement is 144.9 mW. The chip has been processed in a standard 0.35 μm CMOS technology. Active area of chip is 1.37 mm2.
文摘INTRODUCTION The level of man-made CO_(2) emissions worldwide climbed to a new record of 30 billion tons in 2010.In 2011,at the COP17 U.N.Climate Change Conference in Durban,South Africa,high-ranking representatives from around the world met again to discuss solutions.For the building sector,numerous energy-efficiency market changes and benchmarking resolutions,like the mandatory E.U.“nearly Net-Zero-Energy-Building(NET-ZEB’s)2018 and 2020 regulations”for all new public and privately owned buildings are now set up to help minimizing carbon emissions and reverse the negative impact.1 In the United States,the American Institute of Architects(AIA)adopted the 2030 Challenge as a voluntary program,where participating buildings aim to achieve a 90%fossil fuel reduction by 2025,and carbon-neutrality by 2030.2 To accomplish these energy goals,designers must strive to best design and utilize the resources available on a site.However,are these goals of achieving carbon-neutral buildings possible?How can NET-ZEB’s become the curricular standard and practical routine in education and the profession?To date,the basic curricular design process components with integrated project delivery metrics for a robust 3-D/4-D-net-zero regulatory design framework are either incomplete or missing,However,formally-based curriculums have begun to weave carbon-neutral design tools into their pedagogy.This research paper critically compares how these new criteria for digital 3-D-building information modeling(BIM),and“Integrated Project Delivery”are mandating a better integration of collaborative carbon-neutral designs into the curriculum and practice of the profession.The majority of those in architectural academia have been using generative computation primarily for pure,aesthetic form-finding,without applying zero-carbon-energy-driven global performance metrics and CO_(2)e reduction strategies to reiterate derived carbon-neutral designs.The advantage of 3-D-parametric design is that it links variables,dimensions,and materials to geometry in a way that when an input or simulation value changes,the 3-D/4-D model automatically updates all life-cycle scenarios and components simultaneously.
基金supported by the Major Project of Chinese National Programs for Fundamental Research and Development (Grant No. 2010- CB327702)
文摘This paper introduces a new technique of fast acquiring 3D information in microscope based on integral imaging. Experimental results prove that the proposed method has advantageous properties including simple configuration, no requirement of coherent light source and real-time 3D imaging information acquisition. This technique has an important prospect on optical microscopy and 3D display.
基金Project supported in part by the National Natural Science Foundation of China,Science Foundation of Guangdong Province,Zhongshan University,Chinese Post-doctoral Committee.
文摘An iterative procedure is proposed for the variational analysis of Ti:LiNbO3 optical waveguides. A trial solution for the dominant electric field profile of arbitrary-order eigenmodes in strip waveguides and two coupled waveguides is proposed and its parameters are determined using the variational method. The results calculated using this method agree well with those obtained using the finite-element method. The present method has been used to check the accuracy of the effective index method as well as a quasi-analytical technique based on the effective index method. The results show that the effective index method is generally accurate for the fundamental mode and becomes less accurate for higher-order vertical modes.