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Image processing based three-dimensional model reconstruction for cross-platform numerical simulation
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作者 Yu-cheng Sun Yu-hang Huang +5 位作者 Na Li Xiao Han Ai-long Jiang Jin-wu Kang Ji-wu Wang Hai-liang Yu 《China Foundry》 SCIE CAS CSCD 2023年第2期139-147,共9页
Numerical simulation is the most powerful computational and analysis tool for a large variety of engineering and physical problems.For a complex problem relating to multi-field,multi-process and multi-scale,different ... Numerical simulation is the most powerful computational and analysis tool for a large variety of engineering and physical problems.For a complex problem relating to multi-field,multi-process and multi-scale,different computing tools have to be developed so as to solve particular fields at different scales and for different processes.Therefore,the integration of different types of software is inevitable.However,it is difficult to perform the transfer of the meshes and simulated results among software packages because of the lack of shared data formats or encrypted data formats.An image processing based method for three-dimensional model reconstruction for numerical simulation was proposed,which presents a solution to the integration problem by a series of slice or projection images obtained by the post-processing modules of the numerical simulation software.By means of mapping image pixels to meshes of either finite difference or finite element models,the geometry contour can be extracted to export the stereolithography model.The values of results,represented by color,can be deduced and assigned to the meshes.All the models with data can be directly or indirectly integrated into other software as a continued or new numerical simulation.The three-dimensional reconstruction method has been validated in numerical simulation of castings and case studies were provided in this study. 展开更多
关键词 cross-platform numerical simulation 3D model reconstruction image processing SLICE
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ACQUIREMENT AND COMPUTER PROCESSING OF 3-D SURFACE SHAPE DATA
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作者 Shi Jinfa Liang Xichang( Vehicle Engineering College, Chongqing University Beijing Iusitute of Technology) 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 1996年第3期199-204,共1页
The laser scanning and CCD image-transmitting measurement method and principle on acquiring 3-D curved surface shape data are discussed. Computer processing technique of 3-D curved surface shape(be called“ 3 - D surf... The laser scanning and CCD image-transmitting measurement method and principle on acquiring 3-D curved surface shape data are discussed. Computer processing technique of 3-D curved surface shape(be called“ 3 - D surface shape”for short) data is analysed. This technique in- cludes these concrete methods and principles such as data smoothing, fitting, reconstructing ,elimi- nating and so on. The example and result about computer processing of 3- D surface shape data are given . 展开更多
关键词 Laser scanning CCD image-transmitting 3-d surface shape Data processing
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3-D Geological Modeling-Concept,Methods and Key Techniques 被引量:17
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作者 PAN Mao LI Zhaoliang +2 位作者 GAO Zhongbo YANG Yang WU Gengyu 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2012年第4期1031-1036,共6页
3-D geological modeling plays an increasingly important role in Petroleum Geology, Mining Geology and Engineering Geology. The complexity of geological conditions requires different modeling methods in different situa... 3-D geological modeling plays an increasingly important role in Petroleum Geology, Mining Geology and Engineering Geology. The complexity of geological conditions requires different modeling methods in different situations. This paper summarizes the general concept of geological modeling; compares the characteristics of borehole-based modeling, cross-section based modeling and multi- source interactive modeling; analyses key techniques in 3-D geological modeling; and highlights the main difficulties and directions of future studies. 展开更多
关键词 3-d geological modeling geological interpretation methods of modeling quality of models
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Application of 3-D Geoscience Modeling Technology for the Estimation of Solid Mineral Reserves 被引量:15
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作者 PAN Mao LI Jun +1 位作者 WANG Zhangang JIN Jiangjun 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2009年第3期655-660,共6页
Applying new approaches, methods, and technologies for the estimation of reserves can effectively improve the efficiency and accuracy of assessments of solid mineral resources. After analyzing the development of 3-D g... Applying new approaches, methods, and technologies for the estimation of reserves can effectively improve the efficiency and accuracy of assessments of solid mineral resources. After analyzing the development of 3-D geoscience modeling technology (3-D GMT), this paper discusses the application of 3-D GMT for the estimation of solid mineral reserves, emphatically introducing its workflow and two key technologies, 3-D orebody surface modeling, and property modeling. Moreover, the paper analyzes the limitations of traditional methods, such as the section method and geological block method, and points out the advantages of 3-D GMT: building more accurate 3-D orebody models, expressing the internal inhomogeneous attributes of an orebody, reducing the potential for errors in the estimation of reserves, and implementing dynamic estimations of reserves. 展开更多
关键词 3-d geoscience modeling solid mineral resource estimation of reserves surface modeling property modeling
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Optimizing Control of Bio-dissimilation Process of Glycerol to 1,3-Propanedlol 被引量:16
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作者 徐恭贤 邵诚 修志龙 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2008年第1期128-134,共7页
An iterative optimization strategy is proposed and applied to the steady state optimizing control of the bio-dissimilation process of glycerol to 1,3-propanediol in the presence of model-plant mismatch and input const... An iterative optimization strategy is proposed and applied to the steady state optimizing control of the bio-dissimilation process of glycerol to 1,3-propanediol in the presence of model-plant mismatch and input constraints. The scheme is based on the Augmented Integrated System Optimization and Parameter Estimation (AI- SOPE) technique, but a linearization of some performance function in the modified model-based optimization problem of AISOPE is introduced to overcome the difficulty of determining an appropriate penalty parameter. When carrying out the iterative optimization, the penalty coefficient is set to a larger value at the current iteration than at the previous iteration, which can promote the evolution rate of the iterative optimization. Simulation studies illustrate the potential ofthe approach presented for the optimizing control of the bioTdissimilation process of glycerol to 1,3-propanediol. The effects of measurement noise, measured and unmeasured disturbances on the proposed algorithm are also investigated. 展开更多
关键词 steady state optimizing control iterative optimization bio-dissimilation process 1 3-propanediol penalty coefficient model mismatch
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Numerical study on residual current and its impact on mass transport in the Hangzhou Bay and the Changjiang Estuary I. A3-D joint model of the Hangzhou Bay and the Changjiang Estuary 被引量:5
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作者 Zhu Shouxian 1,2 ,Shi Fengyan 1,Zhu Jianrong 1,Ding Pingxing 11 .StateKeyLaboratoryofEstuarineandCoastalResearch ,EastChinaNormalUniversity ,Shanghai 2 0 0 0 6 2 ,China   2.MeteorologyInstituteofthePLAScienceandEngineeringUniversity ,Nanjing 2 11 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2001年第1期1-13,共13页
A 3-D numerical model is set up in a large domain covering the Hangzhou Bay and the Changjiang Estuary based on the ECOM model in orthogonal curvilinear coordinates.The numerical schemes for baroclinic pressure gradie... A 3-D numerical model is set up in a large domain covering the Hangzhou Bay and the Changjiang Estuary based on the ECOM model in orthogonal curvilinear coordinates.The numerical schemes for baroclinic pressure gradient (BPG)terms and convective terms are improved in the paper according to the characteristics of velocity field and mass transport in the area.The model is validated by the simulations of residual current and salinity transport in the Hangzhou Bay and the Changjiang Estuary. 展开更多
关键词 3-d numerical model the Hangzhou Bay the Changjiang Estuary baroclinic pressure gradient convective
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Computer‑aided CT image processing and modeling method for tibia microstructure 被引量:3
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作者 Pengju Wang Su Wang 《Bio-Design and Manufacturing》 CSCD 2020年第1期71-82,共12页
We present a method for computed tomography(CT)image processing and modeling for tibia microstructure,achieved by using computer graphics and fractal theory.Given the large-scale image data of tibia species with DICOM... We present a method for computed tomography(CT)image processing and modeling for tibia microstructure,achieved by using computer graphics and fractal theory.Given the large-scale image data of tibia species with DICOM standard for clinical applications,we take advantage of algorithms such as image binarization,hot pixel removing and close operation to obtain visually clear image for tibia microstructure.All of these images are based on 20 CT scanning images with 30μm slice thickness and 30μm interval and continuous changes in pores.For each pore,we determine its profile by using an improved algorithm for edge detection.Then,to calculate its three-dimensional fractal dimension,we measure the circumference perimeter and area of the pores of bone microstructure using a line fitting method based on the least squares.Subsequently,we put forward an algorithm for the pore profiles through ellipse fitting.The results show that the pores have significant fractal characteristics because of the good linear correlation between the perimeter and the area parameters in log–log scale coordinates system,and the ratio of the elliptical short axis to the long axis through ellipse fitting tends to 0.6501.Based on support vector machine and structural risk minimization principle,we put forward a mapping database theory of structure parameters among the pores of CT images and fractal dimension,Poisson’s ratios,porosity and equivalent aperture.On this basis,we put forward a new concept for 3D modeling called precision-measuring digital expressing to reconstruct tibia microstructure for human hard tissue. 展开更多
关键词 TIBIA CT image processing Fractal dimension Support vector machine 3D modeling
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3-D modeling of rock burst in pillar No. 19 of Fetr6 chromite mine 被引量:4
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作者 S. Dehghan K. Shahriar +1 位作者 P. Maarefvand K. Goshtasbi 《International Journal of Mining Science and Technology》 SCIE EI 2013年第2期237-242,共6页
Fetr6 is an underground mine in which chromite is extracted using stope and pillar mining method. Despite of all improving works such as roof supporting and replacing of ore pillars with concrete pillars, pillar No. 1... Fetr6 is an underground mine in which chromite is extracted using stope and pillar mining method. Despite of all improving works such as roof supporting and replacing of ore pillars with concrete pillars, pillar No. 19 failed and other pillars failed progressively as a domino effect and 4000 m2 of mine collapsed within a few minutes, consequently. For detail investigation, two 3-D numerical models were developed by 3Dec. The first, a base model, was used for estimation of stress on pillars just before failure and the other for investigation of rock burst in pillar No. 19. The results show that discontinuity parameters such as friction angle and shear stiffness is critical parameters in this pillar failure. In addition, it indicates that W/H ratio equal 0.3, the lack of ore extraction strategy and inadequate roof support are the major reasons for this failure. In this paper, the procedure of study was described. 展开更多
关键词 Rock burst Stope and pillar 3-d modeling 3Dec Domino effect Faryab mine
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Simulation of subcritical flow pattern in 180° uniform and convergent open-channel bends using SSIIM 3-D model 被引量:1
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作者 Rasool GHOBADIAN Kamran MOHAMMADI 《Water Science and Engineering》 EI CAS 2011年第3期270-283,共14页
In meandering rivers, the flow pattern is highly complex, with specific characteristics at bends that are not observed along straight paths. A numerical model can be effectively used to predict such flow fields. Since... In meandering rivers, the flow pattern is highly complex, with specific characteristics at bends that are not observed along straight paths. A numerical model can be effectively used to predict such flow fields. Since river bends are not uniform-some are divergent and others convergent-in this study, after the SSIIM 3-D model was calibrated using the result of measurements along a uniform 180° bend with a width of 0.6 m, a similar but convergent 180v bend, 0.6 m to 0.45 m wide, was simulated using the SSI1M 3-D numerical model. Flow characteristics of the convergent 180° bend, including lengthwise and vertical velocity profiles, primary and secondary flows, lengthwise and widtbwise slopes of the water surface, and the helical flow strength, were compared with those of the uniform 180° bend. The verification results of the model show that the numerical model can effectively simulate the flow field in the uniform bend. In addition, this research indicates that, in a convergent channel, the maximum velocity path at a plane near the water surface crosses the channel's centerline at about a 30° to 40° cross-section, while in the uniform bend, this occurs at about the 50° cross-section. The varying range of the water surface elevation is wider in the convergent channel than in the uniform one, and the strength of the helical flow is generally greater in the uniform channel than in the convergent one. Also, unlike the uniform bend, the convergent bend exhibits no rotational cell against the main direction of secondary flow rotation at the 135° cross-section. 展开更多
关键词 flow pattern numerical simulation convergent 180° bend SSIIM 3-d model
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3D Model Reconstruction Based on Process Information 被引量:1
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作者 SHI Yun-fei ZHANG Shu-sheng CAO Ju-lu FAN Hai-tao YANG Yan 《Computer Aided Drafting,Design and Manufacturing》 2007年第2期15-22,共8页
The traditional strategy of 3D model reconstruction mainly concentrates on orthographic projections or engineering drawings. But there are some shortcomings. Such as, only few kinds of solids can be reconstructed, the... The traditional strategy of 3D model reconstruction mainly concentrates on orthographic projections or engineering drawings. But there are some shortcomings. Such as, only few kinds of solids can be reconstructed, the high complexity of time and less information about the 3D model. The research is extended and process card is treated as part of the 3D reconstruction. A set of process data is a superset of 2D engineering drawings set. The set comprises process drawings and process steps, and shows a sequencing and asymptotic course that a part is made from roughcast blank to final product. According to these characteristics, the object to be reconstructed is translated from the complicated engineering drawings into a series of much simpler process drawings. With the plentiful process information added for reconstruction, the disturbances such as irrelevant graph, symbol and label, etc. can be avoided. And more, the form change of both neighbor process drawings is so little that the engineering drawings interpretation has no difficulty; in addition, the abnormal solution and multi-solution can be avoided during reconstruction, and the problems of being applicable to more objects is solved ultimately. Therefore, the utility method for 3D reconstruction model will be possible. On the other hand, the feature information in process cards is provided for reconstruction model. Focusing on process cards, the feasibility and requirements of Working Procedure Model reconstruction is analyzed, and the method to apply and implement the Natural Language Understanding into the 3D reconstruction is studied. The method of asymptotic approximation product was proposed, by which a 3D process model can be constructed automatically and intelligently. The process model not only includes the information about parts characters, but also can deliver the information of design, process and engineering to the downstream applications. 展开更多
关键词 3D model reconstruction natural language understanding process cards working procedure model feature model
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3-D Magnetic Sensor Module for Locating and Tracking MEMS Swallowable Capsule Based on Scalar Form of Magnetic Dipole Model 被引量:2
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作者 WU Xu-dong PENG Cheng-lin HOU Wen-sheng ZHENG Xiao-lin FANG Xing 《Chinese Journal of Biomedical Engineering(English Edition)》 2007年第2期79-86,共8页
MEMS swallowable capsule is a novel technology in the non-invasive surgery. This technology provides a way to diagnose directly into the deep intestinal where the traditional invasive technology implemented, such as X... MEMS swallowable capsule is a novel technology in the non-invasive surgery. This technology provides a way to diagnose directly into the deep intestinal where the traditional invasive technology implemented, such as X-Ray, endoscopy. It is a key for us to locate and track the position of a MEMS capsule in clinical applications. To solve this problem, we implemented a magnetic sensor module based on the scalar form of the magnetic dipole model,which was designed with very small size (5.2 * 2. 1 * 1.2 em) and easy to assemble to satisfy the system requirement. Here we discuss in detail the principle of magnetic dipole model, rules of selecting sensor and functions of the module. Some trials are established to test the characteristic of the module. The results of the Cm experiment demonstrates that the module follows the rules of the new magnetic dipole model form. 展开更多
关键词 sealar form of magnetic dipole model 3-d magnetic sensor module
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3-D crustal-scale gravity model of the San Rafael Block and Payenia volcanic province in Mendoza,Argentina
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作者 Daniel Richarte Marianela Lupari +2 位作者 Agustina Pesce Silvina Nacif Mario Gimenez 《Geoscience Frontiers》 SCIE CAS CSCD 2018年第1期239-248,共10页
The San Rafael Block(SRB)is part of one of the main retroarc volcanic provinces in southern Central Andes in Mendoza,Argentina.This block is located in the Andean foothills between the orogenic front and foreland base... The San Rafael Block(SRB)is part of one of the main retroarc volcanic provinces in southern Central Andes in Mendoza,Argentina.This block is located in the Andean foothills between the orogenic front and foreland basement uplifts of late Miocene age.In order to analyze the geochronological evolution of the Quaternary volcanism in the region,several geologic and geophysical studies have been conducted.Nevertheless,the crust,where the SRB is located,has not been well characterized yet.Based on gravimetric and magnetic data,together with isostatic and elastic thickness analyses,we modeled the crustal structure of the area.Information obtained has allowed us to understand the crust where the SRB and the Payenia volcanic province are located.Bouguer anomalies indicate that the SRB presents higher densities to the North of Cerro Nevado and Moho calculations suggest depths for this block between 40 and 50 km.Determinations of elastic thickness would indicate that the crust supporting the San Rafael Block presents values of approximately 10 km,being enough to support the block loading.However,in the Payenia region,elastic thickness values are close to zero due to the regional temperature increase. 展开更多
关键词 SAN Rafael BLOCK Payenia 3-d CRUSTAL model Asthenospheric wedge
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3-D MODELLING OF COMPUTER AIDED GARMENT DESIGN
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作者 杨建国 朱辉 《Journal of China Textile University(English Edition)》 EI CAS 1991年第1期7-10,共4页
This paper describes a method of the computer aided garment design,and discusses 3-D humanbody,wire frame modelling,approaches of expressing and a shading model of the 3-D garment.
关键词 COMPUTER aided design GARMENTS 3-d human BODY model wire FRAME GARMENT model
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MODELING OF 3-D IMAGES AND SPACE MARKOV CUBIC MESH MODELS
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作者 钱唯 《Journal of Electronics(China)》 1990年第3期280-284,共5页
Three-dimensional(3-D)Markov cubic random mesh models are presented andproved in the form of two theorems in details.Its applications to the modeling and description of3-D images are described.The model presented here... Three-dimensional(3-D)Markov cubic random mesh models are presented andproved in the form of two theorems in details.Its applications to the modeling and description of3-D images are described.The model presented here is a appropriate mathematical tool for thesegmentation,modeling,classification and other processing.Finally,an example is given. 展开更多
关键词 MARKOV CUBIC MESH model modeling 3-d IMAGE
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3-D physical model in strong ground motion numerical simulation:A case study of Kunming basin
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作者 张冬丽 徐锡伟 +2 位作者 赵伯明 陈桂华 解廷伟 《Acta Seismologica Sinica(English Edition)》 CSCD 2007年第2期194-205,共12页
Seismic hazard assessment based on urban active faults can provide scientific bases for city planning and project construction, while numerical simulation of strong ground motion is an important method for seismic haz... Seismic hazard assessment based on urban active faults can provide scientific bases for city planning and project construction, while numerical simulation of strong ground motion is an important method for seismic hazard prediction and assessment. A 3-D physical model in conformity with real strata configuration of (mainly) the Quaternary is a prerequisite to ensure the reliability of the simulation results. In this paper, we give a detailed account of the technical scheme and process for creating a 3-D physical model in Kunming basin. The data used are synthe- sized from seismogeological data, borehole data, topographic data, digital elevation mode (DEM) data, seismic exploration results and wave velocity measurements. Strafigraphic division is based mainly on shear wave velocity, with strata sequence taken into consideration. The model construction is finally accomplished with ArcGIS and many relevant programming techniques via layer-by-layer stacking (in depth direction) of the adjacent medium interfaces (meshes). Meanwhile, a database of 3-D physical models is set up, which provides model data and parameters for strong ground motion simulation. Some processing methods and significant issues are also addressed in the paper in accordance with different types of exploration and experimental data. 展开更多
关键词 strong ground motion 3-d physical model QUATERNARY Kunming basin
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Research of the ATR system based on the 3-D models and L-M BP neural network
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作者 穆成坡 袁志杰 +2 位作者 王纪元 陈远迁 董清先 《Journal of Beijing Institute of Technology》 EI CAS 2014年第3期306-310,共5页
Automatic target recognition (ATR) is an important issue for military applications, the topic of the ATR system belongs to the field of pattern recognition and classification. In the paper, we present an approach fo... Automatic target recognition (ATR) is an important issue for military applications, the topic of the ATR system belongs to the field of pattern recognition and classification. In the paper, we present an approach for building an ATR system with improved artificial neural network to recog- nize and classify the typical targets in the battle field. The invariant features of Hu invariant moments and roundness were selected to be the inputs of the neural network because they have the invari- ances of rotation, translation and scaling. The pictures of the targets are generated by the 3-D mod- els to improve the recognition rate because it is necessary to provide enough pictures for training the artificial neural network. The simulations prove that the approach can be implement ed in the ATR system and it has a high recognition rate and can be applied in real time. 展开更多
关键词 ATR system 3-d models pictures generation pattern recognition Hu invariant round- ness BP neural networ
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Statistical Model of the 3-D Braided Composites Strength
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作者 XIAO Laiyuan ZUO Weiwei CAI Ganwei LIAO Daoxun 《Wuhan University Journal of Natural Sciences》 CAS 2007年第6期1077-1082,共6页
Based on the statistical model for the tensile statistical strength of unidirectional composite materials and the stress analysis of 3-D braided composites, a new method is proposed to calculate the tensile statistica... Based on the statistical model for the tensile statistical strength of unidirectional composite materials and the stress analysis of 3-D braided composites, a new method is proposed to calculate the tensile statistical strength of the 3-D braided compos- ites. With this method, the strength of 3-D braided composites can be calculated with very large accuracy, and the statistical parameters of 3-D braided composites can be determined. The numerical result shows that the tensile statistical strength of 3-D braided composites can be predicted using this method. 展开更多
关键词 3-d braided composites strength calculation statistical model
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Field-Based Automated Survey for Extracting Tree Inventory Attributes and 3-D Models in a Forested Area
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作者 Jasmee Jaafar Juazer Rizal Abdul Hamid Roslina ldris Azman All M. Habib 《Journal of Earth Science and Engineering》 2012年第9期561-570,共10页
Acquisition of tree inventory parameters such as tree position with respect to a local reference coordinate system, tree height, dbh (diameter breast height) and other associated tree attributes is a tedious process... Acquisition of tree inventory parameters such as tree position with respect to a local reference coordinate system, tree height, dbh (diameter breast height) and other associated tree attributes is a tedious process, time consuming, costly and labour intensive. An automatic collection and processing in the field could expedite the process of tree inventory survey and data management. The advent of handheld laser equipments such as the MDL LaserAce 300, should allow rapid acquisition of tree attributes. The instrument measures distances, differences in height and horizontal bearing automatically. This paper describes a study about the automated process of retrieving tree positions, their respective attributes and the creation of 3-D model (three-dimensional model). A software developed in-house known as ASSIST (automated spatial survey information system) was utilized together with the MI)I, LaserAce 300, being the hardware component of the automated system. The capability of MDL LaserAce 9300 in extracting information regarding tree inventory attributes and the 3-D model encompassing the study area was investigated. The results were checked against the data sets acquired by a total station traversing and tacheometric survey respectively. The accuracy of the horizontal and vertical position of points gathered was critically assessed. The accuracy of the MDL LaserAce 300 was found to be less than ±2 m for both planimetric (horizontal) and vertical (height) in the construction of the 3-D model. The study demonstrates the effectiveness of a field-based automation system as a viable option to support forest application requirement. 展开更多
关键词 Measuring laser tree inventory 3-d model.
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3-D Finite-Element Numerical Simulation of Centrifugal Induction Electrosalg Casting Solidification Process
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作者 Xichun Chen, Deguang Zhou, Jie Fu, Weiguo Xu Metallurgy School, University of Science and Technology Beijing Beijing 100083, China 《Journal of University of Science and Technology Beijing》 CSCD 2001年第4期254-258,共5页
A 3-D finite-element numerical simulation model of temperature field for CIESC casting solidification process was developed with the aid of ANSYS software and a series of corresponding experiments were made. The resul... A 3-D finite-element numerical simulation model of temperature field for CIESC casting solidification process was developed with the aid of ANSYS software and a series of corresponding experiments were made. The results showed that the good agreement was obtained between the numerical simulation and the experiments. Based on the numerical simulation results, the characteristics of temperature distribution in the castings during CIESC solidification process were analyzed and summarized. According to the G/R-1/2 method and numerical simulation results, there is no any shrinkage defect in the CIESC casting and structure or casting is fine and compact. 展开更多
关键词 3-d finite-element numerical simulation ANSYS software solidification process centrifugal induction electroslag casting (CIESC) shrinkage defect
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A 3-D in vitro tumor model for investigation of bacteria-mediated gene delivery
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作者 Nelita T.Elliott 《医用生物力学》 EI CAS CSCD 2010年第S1期1-2,共2页
Introduction Cancer is an attractive target of gene therapy and currently represents the disease in most clinical trials[1]. Strategies for cancer gene therapy include: (1) stimulation of immune responses to tumor cel... Introduction Cancer is an attractive target of gene therapy and currently represents the disease in most clinical trials[1]. Strategies for cancer gene therapy include: (1) stimulation of immune responses to tumor cells,(2) delivery of specific enzymes 展开更多
关键词 GENE A 3-d in vitro tumor model for investigation of bacteria-mediated gene delivery
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