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SGT-Net: A Transformer-Based Stratified Graph Convolutional Network for 3D Point Cloud Semantic Segmentation
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作者 Suyi Liu Jianning Chi +2 位作者 Chengdong Wu Fang Xu Xiaosheng Yu 《Computers, Materials & Continua》 SCIE EI 2024年第6期4471-4489,共19页
In recent years,semantic segmentation on 3D point cloud data has attracted much attention.Unlike 2D images where pixels distribute regularly in the image domain,3D point clouds in non-Euclidean space are irregular and... In recent years,semantic segmentation on 3D point cloud data has attracted much attention.Unlike 2D images where pixels distribute regularly in the image domain,3D point clouds in non-Euclidean space are irregular and inherently sparse.Therefore,it is very difficult to extract long-range contexts and effectively aggregate local features for semantic segmentation in 3D point cloud space.Most current methods either focus on local feature aggregation or long-range context dependency,but fail to directly establish a global-local feature extractor to complete the point cloud semantic segmentation tasks.In this paper,we propose a Transformer-based stratified graph convolutional network(SGT-Net),which enlarges the effective receptive field and builds direct long-range dependency.Specifically,we first propose a novel dense-sparse sampling strategy that provides dense local vertices and sparse long-distance vertices for subsequent graph convolutional network(GCN).Secondly,we propose a multi-key self-attention mechanism based on the Transformer to further weight augmentation for crucial neighboring relationships and enlarge the effective receptive field.In addition,to further improve the efficiency of the network,we propose a similarity measurement module to determine whether the neighborhood near the center point is effective.We demonstrate the validity and superiority of our method on the S3DIS and ShapeNet datasets.Through ablation experiments and segmentation visualization,we verify that the SGT model can improve the performance of the point cloud semantic segmentation. 展开更多
关键词 3D point cloud semantic segmentation long-range contexts global-local feature graph convolutional network dense-sparse sampling strategy
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Review of Artificial Intelligence for Oil and Gas Exploration: Convolutional Neural Network Approaches and the U-Net 3D Model
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作者 Weiyan Liu 《Open Journal of Geology》 CAS 2024年第4期578-593,共16页
Deep learning, especially through convolutional neural networks (CNN) such as the U-Net 3D model, has revolutionized fault identification from seismic data, representing a significant leap over traditional methods. Ou... Deep learning, especially through convolutional neural networks (CNN) such as the U-Net 3D model, has revolutionized fault identification from seismic data, representing a significant leap over traditional methods. Our review traces the evolution of CNN, emphasizing the adaptation and capabilities of the U-Net 3D model in automating seismic fault delineation with unprecedented accuracy. We find: 1) The transition from basic neural networks to sophisticated CNN has enabled remarkable advancements in image recognition, which are directly applicable to analyzing seismic data. The U-Net 3D model, with its innovative architecture, exemplifies this progress by providing a method for detailed and accurate fault detection with reduced manual interpretation bias. 2) The U-Net 3D model has demonstrated its superiority over traditional fault identification methods in several key areas: it has enhanced interpretation accuracy, increased operational efficiency, and reduced the subjectivity of manual methods. 3) Despite these achievements, challenges such as the need for effective data preprocessing, acquisition of high-quality annotated datasets, and achieving model generalization across different geological conditions remain. Future research should therefore focus on developing more complex network architectures and innovative training strategies to refine fault identification performance further. Our findings confirm the transformative potential of deep learning, particularly CNN like the U-Net 3D model, in geosciences, advocating for its broader integration to revolutionize geological exploration and seismic analysis. 展开更多
关键词 Deep Learning convolutional Neural Networks (CNN) Seismic Fault Identification U-Net 3D Model Geological Exploration
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Lie symmetry analysis and invariant solutions for the(3+1)-dimensional Virasoro integrable model
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作者 胡恒春 李雅琦 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第4期249-254,共6页
Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with a... Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with arbitrary functions for the(3+1)-dimensional Virasoro integrable model,including the interaction solution between a kink and a soliton,the lump-type solution and periodic solutions,have been studied analytically and graphically. 展开更多
关键词 (3+1)-dimensional Virasoro integrable model Lie symmetry invariant solutions
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GCR-Net:3D Graph convolution-based residual network for robust reconstruction in cerenkov luminescence tomography
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作者 Weitong Li Mengfei Du +7 位作者 Yi Chen Haolin Wang Linzhi Su Huangjian Yi Fengjun Zhao Kang Li Lin Wang Xin Cao 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS CSCD 2023年第1期15-25,共11页
Cerenkov Luminescence Tomography(CLT)is a novel and potential imaging modality which can display the three-dimensional distribution of radioactive probes.However,due to severe ill-posed inverse problem,obtaining accur... Cerenkov Luminescence Tomography(CLT)is a novel and potential imaging modality which can display the three-dimensional distribution of radioactive probes.However,due to severe ill-posed inverse problem,obtaining accurate reconstruction results is still a challenge for traditional model-based methods.The recently emerged deep learning-based methods can directly learn the mapping relation between the surface photon intensity and the distribution of the radioactive source,which effectively improves the performance of CLT reconstruction.However,the previously proposed deep learning-based methods cannot work well when the order of input is disarranged.In this paper,a novel 3D graph convolution-based residual network,GCR-Net,is proposed,which can obtain a robust and accurate reconstruction result from the photon intensity of the surface.Additionally,it is proved that the network is insensitive to the order of input.The performance of this method was evaluated with numerical simulations and in vivo experiments.The results demonstrated that compared with the existing methods,the proposed method can achieve efficient and accurate reconstruction in localization and shape recovery by utilizing threedimensional information. 展开更多
关键词 Cerenkov luminescence tomography optical molecular imaging optical tomography deep learning 3D graph convolution
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Interaction solutions for the second extended(3+1)-dimensional Jimbo–Miwa equation
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作者 马红彩 毛雪 邓爱平 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第6期112-121,共10页
Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions be... Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions between the lump and multi-kink soliton,and the interaction between the lump and triangular periodic soliton are derived by combining a multi-exponential function or trigonometric sine and cosine functions with quadratic functions.Furthermore,periodiclump wave solution is derived via the ansatz including hyperbolic and trigonometric functions.Finally,3D plots,2D curves,density plots,and contour plots with particular choices of the suitable parameters are depicted to illustrate the dynamical features of these solutions. 展开更多
关键词 Hirota bilinear method second extended(3+1)-dimensional Jimbo–Miwa equation lump solution interaction solution
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Segmentation of retinal fluid based on deep learning:application of three-dimensional fully convolutional neural networks in optical coherence tomography images 被引量:3
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作者 Meng-Xiao Li Su-Qin Yu +4 位作者 Wei Zhang Hao Zhou Xun Xu Tian-Wei Qian Yong-Jing Wan 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2019年第6期1012-1020,共9页
AIM: To explore a segmentation algorithm based on deep learning to achieve accurate diagnosis and treatment of patients with retinal fluid.METHODS: A two-dimensional(2D) fully convolutional network for retinal segment... AIM: To explore a segmentation algorithm based on deep learning to achieve accurate diagnosis and treatment of patients with retinal fluid.METHODS: A two-dimensional(2D) fully convolutional network for retinal segmentation was employed. In order to solve the category imbalance in retinal optical coherence tomography(OCT) images, the network parameters and loss function based on the 2D fully convolutional network were modified. For this network, the correlations of corresponding positions among adjacent images in space are ignored. Thus, we proposed a three-dimensional(3D) fully convolutional network for segmentation in the retinal OCT images.RESULTS: The algorithm was evaluated according to segmentation accuracy, Kappa coefficient, and F1 score. For the 3D fully convolutional network proposed in this paper, the overall segmentation accuracy rate is 99.56%, Kappa coefficient is 98.47%, and F1 score of retinal fluid is 95.50%. CONCLUSION: The OCT image segmentation algorithm based on deep learning is primarily founded on the 2D convolutional network. The 3D network architecture proposed in this paper reduces the influence of category imbalance, realizes end-to-end segmentation of volume images, and achieves optimal segmentation results. The segmentation maps are practically the same as the manual annotations of doctors, and can provide doctors with more accurate diagnostic data. 展开更多
关键词 optical COHERENCE tomography IMAGES FLUID segmentation 2D fully convolutional NETWORK 3D fully convolutional NETWORK
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A 3-DIMENSIONAL DATA MODEL FOR VISUALIZING CLOVERLEAF JUNCTION IN A CITY MODEL 被引量:6
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作者 Chen Jun Sun Min Zhou Qiming 《Geo-Spatial Information Science》 1999年第1期9-15,共7页
The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its ma... The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its main body is bestraddle in air,and has aerial intersections between its parts. This complex feature made cloverleaf junction quite different from buildings and terrain, therefore, it is difficult to express this kind of spatial objects in the same way as for buildings and terrain. In this paper,authors analyze spatial characteristics of cloverleaf junction, propose an all-constraint points TIN algorithm to partition cloverleaf junction road surface, and develop a method to visualize cloverleaf junction road surface using TIN. In order to manage cloverleaf junction data efficiently, the authors also analyzed the mechanism of 3DCM data management, extended BLOB type in relational database, and combined R-tree index to manage 3D spatial data. Based on this extension, an appropriate data 展开更多
关键词 3-dimensional CITY model (3DCM) GIS cloverleaf JUNCTION DATA STRUCTURE DATABASE
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Evaluation of Airway Obstruction at Soft Palate Level in Male Patients with Obstructive Sleep Apnea/Hypopnea Syndrome:Dynamic 3-Dimensional CT Imaging of Upper Airway 被引量:10
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作者 肖英 陈雄 +4 位作者 史河水 杨阳 何烈纯 董家琪 孔维佳 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2011年第3期413-418,共6页
This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS) by using dynamic 3-Dimensional(3-D) CT imaging.A tota... This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS) by using dynamic 3-Dimensional(3-D) CT imaging.A total of 41 male patients who presented with 2 of the following symptoms,i.e.,daytime sleepiness and fatigue,frequent snoring,and apnea with witness,were diagnosed as having OSAHS.They underwent full-night polysomnography and then dynamic 3-D CT imaging of the upper airway during quiet breathing and in Muller's maneuver.The soft palate length(SPL),the minimal cross-sectional area of the retropalatal region(mXSA-RP),and the vertical distance from the hard palate to the upper posterior part of the hyoid(hhL) were compared between the two breathing states.These parameters,together with hard palate length(HPL),were also compared between mild/moderate and severe OSAHS groups.Association of these parameters with the severity of OSAHS [as reflected by apnea hypopnea index(AHI) and the lowest saturation of blood oxygen(LSaO2)] was examined.The results showed that 31 patients had severe OSAHS,and 10 mild/moderate OSAHS.All the patients had airway obstruction at soft palate level.mXSA-RP was significantly decreased and SPL remarkably increased during Muller's maneuver as compared with the quiet breathing state.There were no significant differences in these airway parameters(except the position of the hyoid bone) between severe and mild/moderate OSAHS groups.And no significant correlation between these airway parameters and the severity of OSAHS was found.The position of hyoid was lower in the severe OSAHS group than in the mild/moderate OSAHS group.The patients in group with body mass index(BMI)≥26 had higher collapse ratio of mXSA-RP,greater neck circumference and smaller mXSA-RP in the Muller's maneuver than those in group with BMI26(P0.05 for all).It was concluded that dynamic 3-D CT imaging could dynamically show the upper airway changes at soft palate level in OSAHS patients.All the OSAHS patients had airway obstruction of various degrees at soft palate level.But no correlation was observed between the airway change at soft palate level and the severity of OSAHS.The patients in group with BMI≥26 were more likely to develop airway obstruction at soft palate level than those with BMI26. 展开更多
关键词 obstructive sleep apnea/hypopnea syndrome upper airway obstruction soft palate level dynamic computed tomography 3-dimensional imaging
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NOVEL 6-SPS PARALLEL 3-DIMENSIONAL PLATFORM MANIPULATOR AND ITS FORCE/MOTION TRANSMISSION ANALYSIS 被引量:2
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作者 Jin Zhenlin School of Mechanical Engineering, Yanshan University, Qinhuangdao 066004, ChinaGao Feng Hebei University of Technology 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2002年第4期298-302,共5页
The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmissio... The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmission capability, evaluation criteria arepresented. At the orthogonal configuration, the criteria and the relationships between the criteriaand the link lengths are analyzed, which is important since it can provide designer a piece ofvaluable information about how to choose the linear actuators. From the analysis of the results itis shown that the force/motion transmission capabilities of the parallel manipulator arecharacterized by isotropy at the orthogonal configuration. The manipulator is particularly suitablefor certain applications in 6-DOF micromanipulators and 6-axis force/moment transducers. 展开更多
关键词 6-SPS parallel manipulator 3-dimensional platform manipulator ISOTROPY
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Residual symmetry, CRE integrability and interaction solutions of two higher-dimensional shallow water wave equations
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作者 刘希忠 李界通 俞军 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第11期313-319,共7页
Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of t... Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of the two equations are obtained. The CRE method is applied to the two equations to obtain new B?cklund transformations from which a type of interesting interaction solution between solitons and periodic waves is generated. 展开更多
关键词 (3+1)-dimensional shallow water wave equation residual symmetry consistent Riccati expansion
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Thermal effect on endurance performance of 3-dimensional RRAM crossbar array 被引量:2
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作者 卢年端 孙鹏霄 +4 位作者 李泠 刘琦 龙世兵 吕杭炳 刘明 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第5期253-257,共5页
Three-dimensional(3D) crossbar array architecture is one of the leading candidates for future ultra-high density nonvolatile memory applications. To realize the technological potential, understanding the reliability... Three-dimensional(3D) crossbar array architecture is one of the leading candidates for future ultra-high density nonvolatile memory applications. To realize the technological potential, understanding the reliability mechanisms of the3 D RRAM array has become a field of intense research. In this work, the endurance performance of the 3D 1D1 R crossbar array under the thermal effect is investigated in terms of numerical simulation. It is revealed that the endurance performance of the 3D 1D1 R array would be seriously deteriorated under thermal effects as the feature size scales down to a relatively small value. A possible method to alleviate the thermal effects is provided and verified by numerical simulation. 展开更多
关键词 3-dimensional resistive random access memory(RRAM) thermal effect endurance performance
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Rota-Baxter Operators on 3-dimensional Lie Algebras and Solutions of the Classical Yang-Baxter Equation 被引量:1
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作者 Cheng Yong-sheng Wu Lin-li +1 位作者 Wang Pan-yin Du Xian-kun 《Communications in Mathematical Research》 CSCD 2019年第1期81-96,共16页
In this paper,we compute Rota-Baxter operators on the 3-dimensional Lie algebra g whose derived algebra’s dimension is 2.Furthermore,we give the corresponding solutions of the classical Yang-Baxter equation in the 6-... In this paper,we compute Rota-Baxter operators on the 3-dimensional Lie algebra g whose derived algebra’s dimension is 2.Furthermore,we give the corresponding solutions of the classical Yang-Baxter equation in the 6-dimensional Lie algebras g ■ _(ad~*) g~* and some new structures of left-symmetric algebra induced from g and its Rota-Baxter operators. 展开更多
关键词 Rota-Baxter OPERATORS 3-dimensional Lie ALGEBRA classical Yang-Baxter equation left-symmetric ALGEBRA
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Extended symmetry transformation of (3+1)-dimensional generalized nonlinear Schrdinger equation with variable coefficients 被引量:1
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作者 荆建春 李彪 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第1期77-83,共7页
In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach... In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach and symbolic computation. Then based on the extended symmetry, some 3D variable coefficient NLS equations are reduced to other variable coefficient NLS equations or the constant coefficient 3D NLS equation. By using these symmetry transformations, abundant exact solutions of some 3D NLS equations with distributed dispersion, nonlinearity, and gain or loss are obtained from the constant coefficient 3D NLS equation. 展开更多
关键词 3+1)-dimensional nonlinear Schrodinger equation extended symmetry exact solution symbolic computation
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Interactions among special embed-solitons for the (3+1)-dimensional Burgers equation 被引量:1
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作者 张雯婷 戴朝卿 陈未路 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第4期196-199,共4页
With the help of a modified mapping method and a new mapping method, we re-study the (3+1)-dimensional Burgers equation, and derive two families of variable separation solutions. By selecting appropriate functions ... With the help of a modified mapping method and a new mapping method, we re-study the (3+1)-dimensional Burgers equation, and derive two families of variable separation solutions. By selecting appropriate functions in the variable separation solution, we discuss the interaction behaviors among taper-like, plateau-type rings, and rectangle-type embed-solitons in the periodic wave background. All the interaction behaviors are completely elastic, and no phase shift appears after interaction. 展开更多
关键词 3+1)-dimensional Burgers equation modified mapping method interaction between special embed-solitons
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Symmetry analysis and explicit solutions of the (3+1)-dimensional baroclinic potential vorticity equation 被引量:1
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作者 胡晓瑞 陈勇 黄菲 《Chinese Physics B》 SCIE EI CAS CSCD 2010年第8期35-45,共11页
This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmet... This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmetry algebra, symmetry group and group-invariant solutions are analysed. Otherwise, some exact explicit solutions are obtained from the corresponding (2+1)-dimensional equation, the inviscid barotropic nondivergent vorticy equation. To show the properties and characters of these solutions, some plots as well as their possible physical meanings of the atmospheric circulation are given out. 展开更多
关键词 3+1)-dimensional nonlinear baroclinic potential vorticity equation symmetry group group-invariant solution explicit solution
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A more general form of lump solution,lumpoff,and instanton/rogue wave solutions of a reduced (3+1)-dimensional nonlinear evolution equation 被引量:2
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作者 郑攀峰 贾曼 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第12期147-156,共10页
In this manuscript,a reduced(3+1)-dimensional nonlinear evolution equation is studied.We first construct the bilinear formalism of the equation by using the binary Bell polynomials theory,then explore a lump solution ... In this manuscript,a reduced(3+1)-dimensional nonlinear evolution equation is studied.We first construct the bilinear formalism of the equation by using the binary Bell polynomials theory,then explore a lump solution to the special case for z=x.Furthermore,a more general form of lump solution of the equation is found which possesses seven arbitrary parameters and four constraint conditions.By cutting the lump by the induced soliton(s),lumpoff and instanton/rogue wave solutions are also constructed by the more general form of lump solution. 展开更多
关键词 a reduced(3 + 1)-dimensional nonlinear evolution equation more general form of lump solution soliton induced by lump lumpoff and instanton/rogue wave solutions
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New exact solutions of a (3+1)-dimensional Jimbo-Miwa system 被引量:1
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作者 陈元明 马松华 马正义 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第5期247-251,共5页
By using the (G'/G)-expansion method and the variable separation method, a new family of exact solutions of the (3+1)-dimensional Jimbo-Miwa system is obtained. Based on the derived solitary wave solutions, we o... By using the (G'/G)-expansion method and the variable separation method, a new family of exact solutions of the (3+1)-dimensional Jimbo-Miwa system is obtained. Based on the derived solitary wave solutions, we obtain some special localized excitations and study the interactions between two solitary waves of the system. 展开更多
关键词 3+1)-dimensional Jimbo-Miwa system (G'/G)-expansion method exact solutions interactionsbetween two solitary waves
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Wronskian Determinant Solutions for the (3 + 1)-Dimensional Boiti-Leon-Manna-Pempinelli Equation 被引量:1
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作者 Hongcai Ma Yongbin Bai 《Journal of Applied Mathematics and Physics》 2013年第5期18-24,共7页
In this paper, we consider (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli equation. Based on the bilinear form, we derive exact solutions of (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli (BLMP) equation by using th... In this paper, we consider (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli equation. Based on the bilinear form, we derive exact solutions of (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli (BLMP) equation by using the Wronskian technique, which include rational solutions, soliton solutions, positons and negatons. 展开更多
关键词 (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli EQUATION The WRONSKIAN Technique Soliton Negaton Positon
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Classification of All Single Traveling Wave Solutions to (3 + 1)-Dimensional Breaking Soliton Equation 被引量:1
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作者 Yang Li 《Journal of Applied Mathematics and Physics》 2014年第4期41-45,共5页
In order to get the exact traveling wave solutions to nonlinear partial differential equation, the complete discrimination system for polynomial and direct integral method are applied to the considered equation. All s... In order to get the exact traveling wave solutions to nonlinear partial differential equation, the complete discrimination system for polynomial and direct integral method are applied to the considered equation. All single traveling wave solutions to the equation can be obtained. As an example, we give the solutions to (3 + 1)-dimensional breaking soliton equation. 展开更多
关键词 The Nonlinear Partial Differential EQUATION Complete Discrimination System for Polynomial Direct Integral Method TRAVELING Wave Transform (3 + 1)-dimensional BREAKING SOLITON EQUATION
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From 2-dimensional to 3-dimensional: Overcoming dilemmas in intestinal mucosal interpretation
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作者 Richard PG Charlesworth Michael N Marsh 《World Journal of Gastroenterology》 SCIE CAS 2019年第20期2402-2415,共14页
The purpose of this review is to provide a definitive account of small intestinal mucosal structure and interpretation. The coeliac lesion has been well known, but not well described to date and this review aims to id... The purpose of this review is to provide a definitive account of small intestinal mucosal structure and interpretation. The coeliac lesion has been well known, but not well described to date and this review aims to identify the interpretative difficulties which have arisen over time with the histological assessment of coeliac disease. In early coeliac interpretation, there were significant inaccuracies, particularly surrounding intraepithelial lymphocyte counts and the degree of villous flattening which occurred in the tissue. Many of these interpretive pitfalls are still encountered today, increasing the potential for diagnostic errors. These difficulties are mostly due to the fact that stained 2-dimensional sections can never truly represent the 3-dimensional framework of the intestinal tissue under investigation. Therefore, this review offers a critical account occasioned by these 2-dimensional interpretative errors and which, in our opinion, should in general be jettisoned. As a result, we leave a framework regarding the true 3-dimensional knowledge of mucosal structure accrued over the 70-year period of study, and one which is available for future reference. 展开更多
关键词 COELIAC disease HISTOLOGY Diagnosis 2-dimensional 3-dimensional
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