Objectives: To demonstrate the value of 3-dimensional (3-D) ultrasound (US) in the diagnosis of congenital uterine anomalies. Methods: Fifty one infertile patients referred to our US unit during 12 years period, with ...Objectives: To demonstrate the value of 3-dimensional (3-D) ultrasound (US) in the diagnosis of congenital uterine anomalies. Methods: Fifty one infertile patients referred to our US unit during 12 years period, with suspected diagnosis of congenital uterine anomalies by previous HSG or 2D US examinations, were evaluated by transvaginal 3-D US. The 3-D US diagnoses were compared to the initial HSG diagnosis, and to hysteroscopic evaluation when performed. Results: 3-D scan confirmed the initial HSG diagnosis in 27 out of 51 (52.9%) women. The concordancy rates between the initial diagnosis by HSG and 3-D US results were 30.4% for bicornuate uterus;75% for arcuate uterus;83% for septate uterus;and 80% for unicornuate uterus. Of the 13 cases with normal HSG and suspicious 2-D US, 30.8% were found to be normal by 3D sonography. In cases where hysteroscopy was done, the results were 100% in concordance with the 3-D US evaluations. Conclusions: 3-D US is an accurate test for the assessment of uterine congenital anomalies. Its ability to concomitantly visualized, the external uterine contour with the uterine cavity on the same coronal plan, makes this noninvasive, easy to perform test the procedure of choice for the diagnosis of uterine anomalies.展开更多
Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing...Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing interest in applying this technology to diverse applications in medical image analysis.Automated three dimensional Breast Ultrasound is a vital tool for detecting breast cancer,and computer-assisted diagnosis software,developed based on deep learning,can effectively assist radiologists in diagnosis.However,the network model is prone to overfitting during training,owing to challenges such as insufficient training data.This study attempts to solve the problem caused by small datasets and improve model detection performance.Methods We propose a breast cancer detection framework based on deep learning(a transfer learning method based on cross-organ cancer detection)and a contrastive learning method based on breast imaging reporting and data systems(BI-RADS).Results When using cross organ transfer learning and BIRADS based contrastive learning,the average sensitivity of the model increased by a maximum of 16.05%.Conclusion Our experiments have demonstrated that the parameters and experiences of cross-organ cancer detection can be mutually referenced,and contrastive learning method based on BI-RADS can improve the detection performance of the model.展开更多
Objective:To explore the diagnostic value of ultrasound imaging for breast nodules of breast imaging-reporting and data system(BI-RADS)category 3 and above.Methods:From June 2021 to July 2022,163 patients with breast ...Objective:To explore the diagnostic value of ultrasound imaging for breast nodules of breast imaging-reporting and data system(BI-RADS)category 3 and above.Methods:From June 2021 to July 2022,163 patients with breast nodules of BI-RADS 3 or above were selected as the research subjects.After pathological diagnosis,24 cases were malignant breast nodules of BI-RADS 3 or above,while 139 cases were benign breast nodules of BI-RADS 3 or above.The diagnosis rate of malignant and benign breast nodules of BI-RADS 3 or above,including 95%CI,was observed and analyzed.Results:The malignant and benign detection rates of conventional ultrasound were 88.63%and 75.00%,respectively,and the malignant and benign detection rates of ultrasound imaging were 93.18%and 87.50%,respectively,with 95%CIs greater than 0.7.Conclusion:Ultrasound imaging can help improve the diagnostic accuracy of benign and malignant breast nodules of BI-RADS 3 and above and reduce the misdiagnosis rate.展开更多
Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with a...Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with arbitrary functions for the(3+1)-dimensional Virasoro integrable model,including the interaction solution between a kink and a soliton,the lump-type solution and periodic solutions,have been studied analytically and graphically.展开更多
Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions be...Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions between the lump and multi-kink soliton,and the interaction between the lump and triangular periodic soliton are derived by combining a multi-exponential function or trigonometric sine and cosine functions with quadratic functions.Furthermore,periodiclump wave solution is derived via the ansatz including hyperbolic and trigonometric functions.Finally,3D plots,2D curves,density plots,and contour plots with particular choices of the suitable parameters are depicted to illustrate the dynamical features of these solutions.展开更多
The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its ma...The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its main body is bestraddle in air,and has aerial intersections between its parts. This complex feature made cloverleaf junction quite different from buildings and terrain, therefore, it is difficult to express this kind of spatial objects in the same way as for buildings and terrain. In this paper,authors analyze spatial characteristics of cloverleaf junction, propose an all-constraint points TIN algorithm to partition cloverleaf junction road surface, and develop a method to visualize cloverleaf junction road surface using TIN. In order to manage cloverleaf junction data efficiently, the authors also analyzed the mechanism of 3DCM data management, extended BLOB type in relational database, and combined R-tree index to manage 3D spatial data. Based on this extension, an appropriate data展开更多
This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS) by using dynamic 3-Dimensional(3-D) CT imaging.A tota...This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS) by using dynamic 3-Dimensional(3-D) CT imaging.A total of 41 male patients who presented with 2 of the following symptoms,i.e.,daytime sleepiness and fatigue,frequent snoring,and apnea with witness,were diagnosed as having OSAHS.They underwent full-night polysomnography and then dynamic 3-D CT imaging of the upper airway during quiet breathing and in Muller's maneuver.The soft palate length(SPL),the minimal cross-sectional area of the retropalatal region(mXSA-RP),and the vertical distance from the hard palate to the upper posterior part of the hyoid(hhL) were compared between the two breathing states.These parameters,together with hard palate length(HPL),were also compared between mild/moderate and severe OSAHS groups.Association of these parameters with the severity of OSAHS [as reflected by apnea hypopnea index(AHI) and the lowest saturation of blood oxygen(LSaO2)] was examined.The results showed that 31 patients had severe OSAHS,and 10 mild/moderate OSAHS.All the patients had airway obstruction at soft palate level.mXSA-RP was significantly decreased and SPL remarkably increased during Muller's maneuver as compared with the quiet breathing state.There were no significant differences in these airway parameters(except the position of the hyoid bone) between severe and mild/moderate OSAHS groups.And no significant correlation between these airway parameters and the severity of OSAHS was found.The position of hyoid was lower in the severe OSAHS group than in the mild/moderate OSAHS group.The patients in group with body mass index(BMI)≥26 had higher collapse ratio of mXSA-RP,greater neck circumference and smaller mXSA-RP in the Muller's maneuver than those in group with BMI26(P0.05 for all).It was concluded that dynamic 3-D CT imaging could dynamically show the upper airway changes at soft palate level in OSAHS patients.All the OSAHS patients had airway obstruction of various degrees at soft palate level.But no correlation was observed between the airway change at soft palate level and the severity of OSAHS.The patients in group with BMI≥26 were more likely to develop airway obstruction at soft palate level than those with BMI26.展开更多
The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmissio...The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmission capability, evaluation criteria arepresented. At the orthogonal configuration, the criteria and the relationships between the criteriaand the link lengths are analyzed, which is important since it can provide designer a piece ofvaluable information about how to choose the linear actuators. From the analysis of the results itis shown that the force/motion transmission capabilities of the parallel manipulator arecharacterized by isotropy at the orthogonal configuration. The manipulator is particularly suitablefor certain applications in 6-DOF micromanipulators and 6-axis force/moment transducers.展开更多
The purpose of this study was to evaluate the outcome of patients with unresectable hepatocellular carcinoma(HCC) treated by sequential therapy of transcatheter arterial chemoembolization(TACE),three-dimensional c...The purpose of this study was to evaluate the outcome of patients with unresectable hepatocellular carcinoma(HCC) treated by sequential therapy of transcatheter arterial chemoembolization(TACE),three-dimensional conformal radiotherapy(3-DCRT) and high-intensity focused ultrasound(HIFU).From October,2005 to September,2010,120 patients with unresectable HCC received the sequential treatments of several courses of TACE followed in 2-4 weeks by 3-DCRT and then a single session of HIFU with a curative intent.The median tumor irradiation dose was 40 Gy.Tumor response,toxicity and overall survival rate were analyzed.Clinicopathologic factors affecting the primary technique effectiveness and overall survival rates were investigated by univariate analysis or multivariate analysis.All 120 HCC patients were followed up by the last follow-up time.Among these patients,hepatic toxicities due to treatment were notable in 9 cases.Gastrointestinal bleeding after the overall treatment occurred in 2 cases,leukopenia of grade III was detected in 1 case,radiation-induced liver disease(RILD) was observed in 2 patients,and first-and second-degree skin burn around the HIFU treatment zone were observed in 2 patients and 1 patient,respectively.Among 120 patients,23,83 and 14 cases achieved partial response,stable disease and progressive disease,respectively.The overall survival rates at 1 year,3 years and 5 years were 70%,35% and 15%,respectively,with a median survival time of 26 months.Both Child-Pugh liver function grading and radiation dose were determined to be independent predictors for overall survival revealed by the multivariate analysis.It is concluded that the sequential therapy of TACE,3-DCRT and HIFU is a promising therapeutic regimen for unresectable HCC.展开更多
Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of t...Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of the two equations are obtained. The CRE method is applied to the two equations to obtain new B?cklund transformations from which a type of interesting interaction solution between solitons and periodic waves is generated.展开更多
Three-dimensional(3D) crossbar array architecture is one of the leading candidates for future ultra-high density nonvolatile memory applications. To realize the technological potential, understanding the reliability...Three-dimensional(3D) crossbar array architecture is one of the leading candidates for future ultra-high density nonvolatile memory applications. To realize the technological potential, understanding the reliability mechanisms of the3 D RRAM array has become a field of intense research. In this work, the endurance performance of the 3D 1D1 R crossbar array under the thermal effect is investigated in terms of numerical simulation. It is revealed that the endurance performance of the 3D 1D1 R array would be seriously deteriorated under thermal effects as the feature size scales down to a relatively small value. A possible method to alleviate the thermal effects is provided and verified by numerical simulation.展开更多
In this paper,we compute Rota-Baxter operators on the 3-dimensional Lie algebra g whose derived algebra’s dimension is 2.Furthermore,we give the corresponding solutions of the classical Yang-Baxter equation in the 6-...In this paper,we compute Rota-Baxter operators on the 3-dimensional Lie algebra g whose derived algebra’s dimension is 2.Furthermore,we give the corresponding solutions of the classical Yang-Baxter equation in the 6-dimensional Lie algebras g ■ _(ad~*) g~* and some new structures of left-symmetric algebra induced from g and its Rota-Baxter operators.展开更多
In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach...In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach and symbolic computation. Then based on the extended symmetry, some 3D variable coefficient NLS equations are reduced to other variable coefficient NLS equations or the constant coefficient 3D NLS equation. By using these symmetry transformations, abundant exact solutions of some 3D NLS equations with distributed dispersion, nonlinearity, and gain or loss are obtained from the constant coefficient 3D NLS equation.展开更多
With the help of a modified mapping method and a new mapping method, we re-study the (3+1)-dimensional Burgers equation, and derive two families of variable separation solutions. By selecting appropriate functions ...With the help of a modified mapping method and a new mapping method, we re-study the (3+1)-dimensional Burgers equation, and derive two families of variable separation solutions. By selecting appropriate functions in the variable separation solution, we discuss the interaction behaviors among taper-like, plateau-type rings, and rectangle-type embed-solitons in the periodic wave background. All the interaction behaviors are completely elastic, and no phase shift appears after interaction.展开更多
This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmet...This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmetry algebra, symmetry group and group-invariant solutions are analysed. Otherwise, some exact explicit solutions are obtained from the corresponding (2+1)-dimensional equation, the inviscid barotropic nondivergent vorticy equation. To show the properties and characters of these solutions, some plots as well as their possible physical meanings of the atmospheric circulation are given out.展开更多
In this manuscript,a reduced(3+1)-dimensional nonlinear evolution equation is studied.We first construct the bilinear formalism of the equation by using the binary Bell polynomials theory,then explore a lump solution ...In this manuscript,a reduced(3+1)-dimensional nonlinear evolution equation is studied.We first construct the bilinear formalism of the equation by using the binary Bell polynomials theory,then explore a lump solution to the special case for z=x.Furthermore,a more general form of lump solution of the equation is found which possesses seven arbitrary parameters and four constraint conditions.By cutting the lump by the induced soliton(s),lumpoff and instanton/rogue wave solutions are also constructed by the more general form of lump solution.展开更多
By using the (G'/G)-expansion method and the variable separation method, a new family of exact solutions of the (3+1)-dimensional Jimbo-Miwa system is obtained. Based on the derived solitary wave solutions, we o...By using the (G'/G)-expansion method and the variable separation method, a new family of exact solutions of the (3+1)-dimensional Jimbo-Miwa system is obtained. Based on the derived solitary wave solutions, we obtain some special localized excitations and study the interactions between two solitary waves of the system.展开更多
In this paper, we consider (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli equation. Based on the bilinear form, we derive exact solutions of (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli (BLMP) equation by using th...In this paper, we consider (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli equation. Based on the bilinear form, we derive exact solutions of (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli (BLMP) equation by using the Wronskian technique, which include rational solutions, soliton solutions, positons and negatons.展开更多
In order to get the exact traveling wave solutions to nonlinear partial differential equation, the complete discrimination system for polynomial and direct integral method are applied to the considered equation. All s...In order to get the exact traveling wave solutions to nonlinear partial differential equation, the complete discrimination system for polynomial and direct integral method are applied to the considered equation. All single traveling wave solutions to the equation can be obtained. As an example, we give the solutions to (3 + 1)-dimensional breaking soliton equation.展开更多
文摘Objectives: To demonstrate the value of 3-dimensional (3-D) ultrasound (US) in the diagnosis of congenital uterine anomalies. Methods: Fifty one infertile patients referred to our US unit during 12 years period, with suspected diagnosis of congenital uterine anomalies by previous HSG or 2D US examinations, were evaluated by transvaginal 3-D US. The 3-D US diagnoses were compared to the initial HSG diagnosis, and to hysteroscopic evaluation when performed. Results: 3-D scan confirmed the initial HSG diagnosis in 27 out of 51 (52.9%) women. The concordancy rates between the initial diagnosis by HSG and 3-D US results were 30.4% for bicornuate uterus;75% for arcuate uterus;83% for septate uterus;and 80% for unicornuate uterus. Of the 13 cases with normal HSG and suspicious 2-D US, 30.8% were found to be normal by 3D sonography. In cases where hysteroscopy was done, the results were 100% in concordance with the 3-D US evaluations. Conclusions: 3-D US is an accurate test for the assessment of uterine congenital anomalies. Its ability to concomitantly visualized, the external uterine contour with the uterine cavity on the same coronal plan, makes this noninvasive, easy to perform test the procedure of choice for the diagnosis of uterine anomalies.
基金Macao Polytechnic University Grant(RP/FCSD-01/2022RP/FCA-05/2022)Science and Technology Development Fund of Macao(0105/2022/A).
文摘Background Deep convolutional neural networks have garnered considerable attention in numerous machine learning applications,particularly in visual recognition tasks such as image and video analyses.There is a growing interest in applying this technology to diverse applications in medical image analysis.Automated three dimensional Breast Ultrasound is a vital tool for detecting breast cancer,and computer-assisted diagnosis software,developed based on deep learning,can effectively assist radiologists in diagnosis.However,the network model is prone to overfitting during training,owing to challenges such as insufficient training data.This study attempts to solve the problem caused by small datasets and improve model detection performance.Methods We propose a breast cancer detection framework based on deep learning(a transfer learning method based on cross-organ cancer detection)and a contrastive learning method based on breast imaging reporting and data systems(BI-RADS).Results When using cross organ transfer learning and BIRADS based contrastive learning,the average sensitivity of the model increased by a maximum of 16.05%.Conclusion Our experiments have demonstrated that the parameters and experiences of cross-organ cancer detection can be mutually referenced,and contrastive learning method based on BI-RADS can improve the detection performance of the model.
文摘Objective:To explore the diagnostic value of ultrasound imaging for breast nodules of breast imaging-reporting and data system(BI-RADS)category 3 and above.Methods:From June 2021 to July 2022,163 patients with breast nodules of BI-RADS 3 or above were selected as the research subjects.After pathological diagnosis,24 cases were malignant breast nodules of BI-RADS 3 or above,while 139 cases were benign breast nodules of BI-RADS 3 or above.The diagnosis rate of malignant and benign breast nodules of BI-RADS 3 or above,including 95%CI,was observed and analyzed.Results:The malignant and benign detection rates of conventional ultrasound were 88.63%and 75.00%,respectively,and the malignant and benign detection rates of ultrasound imaging were 93.18%and 87.50%,respectively,with 95%CIs greater than 0.7.Conclusion:Ultrasound imaging can help improve the diagnostic accuracy of benign and malignant breast nodules of BI-RADS 3 and above and reduce the misdiagnosis rate.
文摘Lie symmetry analysis is applied to a(3+1)-dimensional Virasoro integrable model and the corresponding similarity reduction equations are obtained with the different infinitesimal generators.Invariant solutions with arbitrary functions for the(3+1)-dimensional Virasoro integrable model,including the interaction solution between a kink and a soliton,the lump-type solution and periodic solutions,have been studied analytically and graphically.
文摘Based on the Hirota bilinear method,the second extended(3+1)-dimensional Jimbo–Miwa equation is established.By Maple symbolic calculation,lump and lump-kink soliton solutions are obtained.The interaction solutions between the lump and multi-kink soliton,and the interaction between the lump and triangular periodic soliton are derived by combining a multi-exponential function or trigonometric sine and cosine functions with quadratic functions.Furthermore,periodiclump wave solution is derived via the ansatz including hyperbolic and trigonometric functions.Finally,3D plots,2D curves,density plots,and contour plots with particular choices of the suitable parameters are depicted to illustrate the dynamical features of these solutions.
文摘The research work has been seldom done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its main body is bestraddle in air,and has aerial intersections between its parts. This complex feature made cloverleaf junction quite different from buildings and terrain, therefore, it is difficult to express this kind of spatial objects in the same way as for buildings and terrain. In this paper,authors analyze spatial characteristics of cloverleaf junction, propose an all-constraint points TIN algorithm to partition cloverleaf junction road surface, and develop a method to visualize cloverleaf junction road surface using TIN. In order to manage cloverleaf junction data efficiently, the authors also analyzed the mechanism of 3DCM data management, extended BLOB type in relational database, and combined R-tree index to manage 3D spatial data. Based on this extension, an appropriate data
文摘This study examined the dynamic characteristics of upper airway collapse at soft palate level in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS) by using dynamic 3-Dimensional(3-D) CT imaging.A total of 41 male patients who presented with 2 of the following symptoms,i.e.,daytime sleepiness and fatigue,frequent snoring,and apnea with witness,were diagnosed as having OSAHS.They underwent full-night polysomnography and then dynamic 3-D CT imaging of the upper airway during quiet breathing and in Muller's maneuver.The soft palate length(SPL),the minimal cross-sectional area of the retropalatal region(mXSA-RP),and the vertical distance from the hard palate to the upper posterior part of the hyoid(hhL) were compared between the two breathing states.These parameters,together with hard palate length(HPL),were also compared between mild/moderate and severe OSAHS groups.Association of these parameters with the severity of OSAHS [as reflected by apnea hypopnea index(AHI) and the lowest saturation of blood oxygen(LSaO2)] was examined.The results showed that 31 patients had severe OSAHS,and 10 mild/moderate OSAHS.All the patients had airway obstruction at soft palate level.mXSA-RP was significantly decreased and SPL remarkably increased during Muller's maneuver as compared with the quiet breathing state.There were no significant differences in these airway parameters(except the position of the hyoid bone) between severe and mild/moderate OSAHS groups.And no significant correlation between these airway parameters and the severity of OSAHS was found.The position of hyoid was lower in the severe OSAHS group than in the mild/moderate OSAHS group.The patients in group with body mass index(BMI)≥26 had higher collapse ratio of mXSA-RP,greater neck circumference and smaller mXSA-RP in the Muller's maneuver than those in group with BMI26(P0.05 for all).It was concluded that dynamic 3-D CT imaging could dynamically show the upper airway changes at soft palate level in OSAHS patients.All the OSAHS patients had airway obstruction of various degrees at soft palate level.But no correlation was observed between the airway change at soft palate level and the severity of OSAHS.The patients in group with BMI≥26 were more likely to develop airway obstruction at soft palate level than those with BMI26.
基金This project is supported by National 863 Plan of China (No. 512-9804- 02) and 863 Opening Robot Laboratory Foundation of Shenyang Institute Automation of Chinese Academy of Sciences.
文摘The unique design for a novel 6-SPS parallel 3-dimensional platformmanipulator with an orthogonal configuration is investigated. The layout feature of the parallelmanipulator is described. Its force/motion transmission capability, evaluation criteria arepresented. At the orthogonal configuration, the criteria and the relationships between the criteriaand the link lengths are analyzed, which is important since it can provide designer a piece ofvaluable information about how to choose the linear actuators. From the analysis of the results itis shown that the force/motion transmission capabilities of the parallel manipulator arecharacterized by isotropy at the orthogonal configuration. The manipulator is particularly suitablefor certain applications in 6-DOF micromanipulators and 6-axis force/moment transducers.
文摘The purpose of this study was to evaluate the outcome of patients with unresectable hepatocellular carcinoma(HCC) treated by sequential therapy of transcatheter arterial chemoembolization(TACE),three-dimensional conformal radiotherapy(3-DCRT) and high-intensity focused ultrasound(HIFU).From October,2005 to September,2010,120 patients with unresectable HCC received the sequential treatments of several courses of TACE followed in 2-4 weeks by 3-DCRT and then a single session of HIFU with a curative intent.The median tumor irradiation dose was 40 Gy.Tumor response,toxicity and overall survival rate were analyzed.Clinicopathologic factors affecting the primary technique effectiveness and overall survival rates were investigated by univariate analysis or multivariate analysis.All 120 HCC patients were followed up by the last follow-up time.Among these patients,hepatic toxicities due to treatment were notable in 9 cases.Gastrointestinal bleeding after the overall treatment occurred in 2 cases,leukopenia of grade III was detected in 1 case,radiation-induced liver disease(RILD) was observed in 2 patients,and first-and second-degree skin burn around the HIFU treatment zone were observed in 2 patients and 1 patient,respectively.Among 120 patients,23,83 and 14 cases achieved partial response,stable disease and progressive disease,respectively.The overall survival rates at 1 year,3 years and 5 years were 70%,35% and 15%,respectively,with a median survival time of 26 months.Both Child-Pugh liver function grading and radiation dose were determined to be independent predictors for overall survival revealed by the multivariate analysis.It is concluded that the sequential therapy of TACE,3-DCRT and HIFU is a promising therapeutic regimen for unresectable HCC.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 11975156 and 12175148)。
文摘Two(3+1)-dimensional shallow water wave equations are studied by using residual symmetry and the consistent Riccati expansion(CRE) method. Through localization of residual symmetries, symmetry reduction solutions of the two equations are obtained. The CRE method is applied to the two equations to obtain new B?cklund transformations from which a type of interesting interaction solution between solitons and periodic waves is generated.
基金Project supported by the Opening Project of Key Laboratory of Microelectronics Devices&Integrated Technology,Institute of Microelectronics of Chinese Academy of Sciences,the National High Technology Research and Development Program of China(Grant No.2014AA032901)the National Natural Science Foundation of China(Grant Nos.61574166,61334007,61306117,61322408,61221004,and 61274091)+1 种基金Beijing Training Project for the Leading Talents in S&T,China(Grant No.Z151100000315008)the CAEP Microsystem and THz Science and Technology Foundation,China(Grant No.CAEPMT201504)
文摘Three-dimensional(3D) crossbar array architecture is one of the leading candidates for future ultra-high density nonvolatile memory applications. To realize the technological potential, understanding the reliability mechanisms of the3 D RRAM array has become a field of intense research. In this work, the endurance performance of the 3D 1D1 R crossbar array under the thermal effect is investigated in terms of numerical simulation. It is revealed that the endurance performance of the 3D 1D1 R array would be seriously deteriorated under thermal effects as the feature size scales down to a relatively small value. A possible method to alleviate the thermal effects is provided and verified by numerical simulation.
基金The NSF(11047030 and 11771122) of Chinathe Science and Technology Program(152300410061) of Henan Province
文摘In this paper,we compute Rota-Baxter operators on the 3-dimensional Lie algebra g whose derived algebra’s dimension is 2.Furthermore,we give the corresponding solutions of the classical Yang-Baxter equation in the 6-dimensional Lie algebras g ■ _(ad~*) g~* and some new structures of left-symmetric algebra induced from g and its Rota-Baxter operators.
基金Project supported by the National Natural Science Foundation of China (Grant No. 11041003)the Ningbo Natural Science Foundation, China (Grant No. 2009B21003)K.C. Wong Magna Fund in Ningbo University, China
文摘In this paper, the extended symmetry transformation of (3+1)-dimensional (3D) generalized nonlinear Schrodinger (NLS) equations with variable coefficients is investigated by using the extended symmetry approach and symbolic computation. Then based on the extended symmetry, some 3D variable coefficient NLS equations are reduced to other variable coefficient NLS equations or the constant coefficient 3D NLS equation. By using these symmetry transformations, abundant exact solutions of some 3D NLS equations with distributed dispersion, nonlinearity, and gain or loss are obtained from the constant coefficient 3D NLS equation.
基金Project supported by the National Natural Science Foundation of China (Grant No. 11005092)the Undergraduate Scientific and Technological Innovation Project of Zhejiang Province of China (Grant No. 2012R412018)the Undergraduate Innovative Base Program of Zhejiang A & F University
文摘With the help of a modified mapping method and a new mapping method, we re-study the (3+1)-dimensional Burgers equation, and derive two families of variable separation solutions. By selecting appropriate functions in the variable separation solution, we discuss the interaction behaviors among taper-like, plateau-type rings, and rectangle-type embed-solitons in the periodic wave background. All the interaction behaviors are completely elastic, and no phase shift appears after interaction.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.10735030,90718041 and 40975038)Shanghai Leading Academic Discipline Project(Grant No.B412)Program for Changjiang Scholars and Innovative Research Team in University(Grant No.IRT0734)
文摘This paper investigates an important high-dimensional model in the atmospheric and oceanic dynamics-(3+1)- dimensional nonlinear baroclinic potential vorticity equation by the classical Lie group method. Its symmetry algebra, symmetry group and group-invariant solutions are analysed. Otherwise, some exact explicit solutions are obtained from the corresponding (2+1)-dimensional equation, the inviscid barotropic nondivergent vorticy equation. To show the properties and characters of these solutions, some plots as well as their possible physical meanings of the atmospheric circulation are given out.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11675084 and 11435005)the Fund from the Educational Commission of Zhejiang Province,China(Grant No.Y201737177)+1 种基金Ningbo Natural Science Foundation(Grant No.2015A610159)the K C Wong Magna Fund in Ningbo University
文摘In this manuscript,a reduced(3+1)-dimensional nonlinear evolution equation is studied.We first construct the bilinear formalism of the equation by using the binary Bell polynomials theory,then explore a lump solution to the special case for z=x.Furthermore,a more general form of lump solution of the equation is found which possesses seven arbitrary parameters and four constraint conditions.By cutting the lump by the induced soliton(s),lumpoff and instanton/rogue wave solutions are also constructed by the more general form of lump solution.
基金Project supported by the Scientific Research Foundation of Lishui University, China (Grant No. KZ201110)
文摘By using the (G'/G)-expansion method and the variable separation method, a new family of exact solutions of the (3+1)-dimensional Jimbo-Miwa system is obtained. Based on the derived solitary wave solutions, we obtain some special localized excitations and study the interactions between two solitary waves of the system.
文摘In this paper, we consider (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli equation. Based on the bilinear form, we derive exact solutions of (3 + 1)-dimensional Boiti-Leon-Manna-Pempinelli (BLMP) equation by using the Wronskian technique, which include rational solutions, soliton solutions, positons and negatons.
文摘In order to get the exact traveling wave solutions to nonlinear partial differential equation, the complete discrimination system for polynomial and direct integral method are applied to the considered equation. All single traveling wave solutions to the equation can be obtained. As an example, we give the solutions to (3 + 1)-dimensional breaking soliton equation.