3.0 Tesla magnetic resonance imaging: A new standard in liver imaging?

An ever-increasing number of 3.0 Tesla(T) magnets are installed worldwide. Moving from the standard of 1.5 T to higher field strength implies a number of potential advantage and drawbacks, requiring careful optimization of imaging protocols or implementation of novel hardware components. Clinical practice and literature review suggest that state-of-the-art 3.0 T is equivalent to 1.5 T in the assessment of focal liver lesions and diffuse liver disease. Therefore, further technical improvements are needed in order to fully exploit the potential of higher field strength.

Potential applications of 7 Tesla magnetic resonance imaging in paediatric neuroimaging:Feasibility and challenges

The integration of 7 Tesla magnetic resonance imaging(7 T MRI)in adult patients has marked a revolutionary stride in radiology.In this article we explore the feasibility of 7 T MRI in paediatric practice,emphasizing its feasibility,applications,challenges,and safety considerations.The heightened resolution and tissue contrast of 7 T MRI offer unprecedented diagnostic accuracy,particularly in neuroimaging.Applications range from neuro-oncology to neonatal brain imaging,showcasing its efficacy in detecting subtle structural abnormalities and providing enhanced insights into neurological conditions.Despite the promise,challenges such as high cost,discomfort,and safety concerns necessitate careful consideration.Research suggests that,with precautions,7 T MRI is feasible in paediatrics,yet ongoing studies and safety assessments are imperative.

3.0 Tesla vs 1.5 Tesla breast magnetic resonance imaging in newly diagnosed breast cancer patients

AIM:To compare 3.0 Tesla(T) vs 1.5T magnetic resonance(MR) imaging systems in newly diagnosed breast cancer patients.METHODS:Upon Institutional Review Board approval,a Health Insurance Portability and Accountability Actcompliant retrospective review of 147 consecutive 3.0T MR examinations and 98 consecutive 1.5T MR examinations in patients with newly diagnosed breast cancer between 7/2009 and 5/2010 was performed.Eleven patients who underwent neoadjuvant chemotherapy in the 3.0T group were excluded.Mammographically occult suspicious lesions(BIRADS Code 4 and 5) additional to the index cancer in the ipsilateral and contralateral breast were identified.Lesion characteristics and pathologic diagnoses were recorded,and results achieved with both systems compared.Statistical significance was analyzed using Fisher’s exact test.RESULTS:In the 3.0T group,206 suspicious lesions were identified in 55%(75/136) of patients and 96%(198/206) of these lesions were biopsied.In the 1.5T group,98 suspicious lesions were identified in 53%(52/98) of patients and 90%(88/98) of these lesions were biopsied.Biopsy results yielded additional malignancies in 24% of patients in the 3.0T group vs 14% of patients in the 1.5T group(33/136 vs 14/98,P = 0.07).Average size and histology of the additional cancers was comparable.Of patients who had a suspicious MR imaging study,additional cancers were found in 44% of patients in the 3.0T group vs 27% in the 1.5T group(33/75 vs 14/52,P = 0.06),yielding a higher positive predictive value(PPV) for biopsies performed with the 3.0T system.CONCLUSION:3.0T MR imaging detected more additional malignancies in patients with newly diagnosed breast cancer and yielded a higher PPV for biopsies performed with the 3.0T system.

Optimal b value of diffusion-weighted imaging on a 3.0T magnetic resonance scanner in Crohn's disease

AIM: To determine the optimal b value of diffusion-weighted imaging for detecting active inflammation in Crohn’s disease.

Prostate magnetic resonance imaging at 3 Tesla:Is administration of hyoscine-N-butyl-bromide mandatory?

AIM: To evaluate the value of administration of hyoscine-N-butyl-bromide (HBB) for image quality magnetic resonance imaging (MRI) of the prostate. METHODS: Seventy patients were retrospectively included in the study. Thirty-five patients were examined with administration of 40 milligrams of HBB (Buscopan ; Boehringer, Ingelheim, Germany); 35 patients were examined without HBB. A multiparametric MRI protocol was performed on a 3.0 Tesla scanner without using an endorectal coil. The following criteria were evaluated independently by two experienced radiologists on a five-point Likert scale: anatomical details (delineation between peripheral and transitional zone of the prostate, visualisation of the capsule, depiction of the neurovascular bundles); visualisation of lymph nodes; motion related artefacts; and overall image quality.RESULTS: Comparison of anatomical details between the two cohorts showed no statistically significant difference (3.9 ± 0.7 vs 4.0 ± 0.9, P = 0.54, and 3.8 ± 0.7 vs 4.2 ± 0.6, P = 0.07) for both readers. There was no significant advantage regarding depiction of local and iliac lymph nodes (3.9 ± 0.6 vs 4.2 ± 0.6, P = 0.07, and 3.8 ± 0.9 vs 4.1 ± 0.8, P = 0.19). Motion arte- facts were rated as 'none' to 'few' in both groups and showed no statistical difference (2.3 ± 1.0 vs 1.9 ± 0.9, P = 0.19, and 2.3 ± 1.1 vs 1.9 ± 0.7, P = 0.22). Overall image quality was rated 'good' in average for both cohorts without significant difference (4.0 ± 0.6 vs 4.0 ± 0.9, P = 0.78, and 3.8 ± 0.8 vs 4.2 ± 0.6, P = 0.09). CONCLUSION: The results demonstrated no significant effect of HBB administration on image quality. The study suggests that use of HBB is not mandatory for MRI of the prostate at 3.0 Tesla.

Does sevoflurane sedation in pediatric patients lead to“pseudo”leptomeningeal enhancement in the brain on 3 Tesla magnetic resonance imaging?

BACKGROUND Prominent leptomeningeal contrast enhancement(LMCE)in the brain is observed in some pediatric patients during sedation for imaging.However,based on clinical history and cerebrospinal fluid analysis,the patients are not acutely ill and do not exhibit meningeal signs.Our study determined whether sevoflurane inhalation in pediatric patients led to this pattern of‘pseudo’LMCE(pLMCE)on 3 Tesla magnetic resonance imaging(MRI).AIM To highlight the significance of pLMCE in pediatric patients undergoing enhanced brain MRI under sedation to avoid misinterpretation in reports.METHODS A retrospective cross-sectional evaluation of pediatric patients between 0-8 years of age was conducted.The patients underwent enhanced brain MRI under inhaled sevoflurane.The LMCE grade was determined by two radiologists,and interobserver variability of the grade was calculated using Cohen’s kappa.The LMCE grade was correlated with duration of sedation,age and weight using the Spearman rho rank correlation.RESULTS A total of 63 patients were included.Fourteen(22.2%)cases showed mild LMCE,48(76.1%)cases showed moderate LMCE,and 1 case(1.6%)showed severe LMCE.We found substantial agreement between the two radiologists in detection of pLMCE on post-contrast T1 imaging(kappa value=0.61;P<0.001).Additionally,we found statistically significant inverse and moderate correlations between patient weight and age.There was no correlation between duration of sedation and pLMCE.CONCLUSION pLMCE is relatively common on post-contrast spin echo T1-weighted MRI of pediatric patients sedated by sevoflurane due to their fragile and immature vasculature.It should not be misinterpreted for meningeal pathology.Knowing pertinent clinical history of the child is an essential prerequisite to avoid radiological overcalling and the subsequent burden of additional investigations.

Patient’s Comfort and Technical Quality Exams at 1.5 and 3.0 T Magnetic Resonance Imaging

Increased interest of clinicians for using 3.0 T magnetic resonance imaging (MRI), as imaging modality of choice for their patients, has been evident in the past few years. The aim of this study was to compare the technical quality of the obtained tomography using 3.0 T and 1.5 T MRI, and to compare the subjective feeling of discomfort of patients and subjective acoustic noise experience during imaging using MRI at 3.0 T and 1.5 T. Brain MRI (1.5 and 3.0 T) was performed in 58 patients, according to a standardized protocol. All studies have been randomly described by independent two radiologists. The reference standard for the existence of technical artifact is established on the basis of both radiologists’ consensus. We also compared the subjective feelings of the discomfort and acoustic noise during the both MRI (1.5 T and 3.0 T) exams. Artifacts were significantly more common during 3.0 T MRI in comparison with the 1.5 T MRI (χ2 = 5.286, P < 0.05), as well as in male patients (χ2 = 8.841, P < 0.05), and sub-jective assessments of discomfort and acoustic noise were higher in patients who underwent imaging using 3.0 T MRI, (χ2 = 125.959, df = 1, P < 0.001) and in females (χ2 = 195.449, df = 1, P < 0.001). Additional research is needed to prove that appropriate information for patients about the discomfort during 3.0 T MRI and their psychological preparation is very important element for optimal use of 3.0 T MRI in daily clinical practice.

Magnetic resonance imaging in breast cancer:A literature review and future perspectives

Early detection and diagnosis of breast cancer are essential for successful treatment. Currently mammography and ultrasound are the basic imaging techniques for the detection and localization of breast tumors. The low sensitivity and specificity of these imaging tools resulted in a demand for new imaging modalities and breast magnetic resonance imaging(MRI) has become increasingly important in the detection and delineation of breast cancer in daily practice. However, the clinical benefits of the use of pre-operative MRI in women with newly diagnosed breast cancer is still a matter of debate. The main additional diagnostic value of MRI relies on specific situations such as detecting multifocal, multicentric or contralateral disease unrecognized on conventional assessment(particularly in patients diagnosed with invasive lobular carcinoma), assessing the response to neoadjuvant chemotherapy, detection of cancer in dense breast tissue, recognition of an occult primary breast cancer in patients presenting with cancer metastasis in axillary lymph nodes, among others. Nevertheless, the development of new MRI technolo-gies such as diffusion-weighted imaging, proton spectroscopy and higher field strength 7.0 T imaging offer a new perspective in providing additional information in breast abnormalities. We conducted an expert literature review on the value of breast MRI in diagnosing and staging breast cancer, as well as the future potentials of new MRI technologies.

飞利浦Ingenia 3.0 T磁共振成像仪射频系统故障三例

磁共振成像无电离辐射且软组织成像效果较好,已成为常规体检和疾病诊断非常重要的医学影像诊疗技术之一。磁共振设备结构复杂,维修及维护成本较高,长期高负荷的运转会导致磁共振设备故障率增加。本文总结了本院飞利浦Ingenia 3.0 T磁共振设备射频系统故障三例,包括de-tuned印刷电路板故障、射频放大器故障及体线圈故障。文中对三例飞利浦磁共振设备射频系统故障的表现进行了描述,对故障产生的原因进行了分析并介绍了故障排除过程,包括观察外观、提取后台日志参数、测量疑似受损部件指标、更换受损部件以及系统测试。通过深入分析射频系统故障案例,分享维修经验,以期提高设备使用率。

Imaging for deep brain stimulation:The zona incerta at 7 Tesla

AIM:To evaluate different promising magnetic resonance imaging(MRI) methods at 7.0 Tesla(T) for the pre-stereotactic visualization of the zona incerta(ZI).METHODS:Two neuroradiologists qualitatively and quantitatively examined T2-turbo spin-echo(T2-TSE),T1-weighted gradient-echo,as well as FLASH2D-T2Star and susceptibility-weighted imaging(SWI) for the visualization of the ZI at 7.0 T MRI.Delineation and image quality for the ZI were independently examined using a 6-scale grading system.Inter-rater reliability using Cohen's kappa coefficient(κ) were assessed.Contrast-tonoise ratios(CNR),and signal-to-noise ratios(SNR) for the ZI were calculated for all sequences.Differences in delineation,SNR,and CNR between the sequences were statistically assessed using a paired t-test.For the anatomic validation the coronal FLASH2D-T2Star images were co-registered with a stereotactic atlas(Schaltenbrand-Wahren).RESULTS:The rostral part of the ZI(rZI) could easily be identified and was best and reliably visualized in the coronal FLASH2D-T2Star images.The caudal part was not definable in any of the sequences.No major artifacts in the rZI were observed in any of the scans.FLASH2D-T2Star and SWI imaging offered significant higher CNR values for the rZI compared to T2-TSE images(P > 0.05).The co-registration of the coronal FLASH2D-T2Star images with the stereotactic atlas schema(Schaltenbrand-Wahren) confirmed the correct localization of the ZI in all cases.CONCLUSION:FLASH2D-T2Star imaging(particularly coronal view) provides the reliable and currently optimal visualization of the rZI at 7.0 T.These results can facilitate a better and more precise targeting of the caudal part of the ZI than ever before.

3.0T磁共振成像联合多层螺旋电子计算机断层扫描对肛瘘临床分型的诊断价值

目的探讨3.0 T磁共振成像(MRI)联合多层螺旋电子计算机断层扫描(MSCT)对肛瘘临床分型的诊断价值。方法回顾性分析2020年1月至2022年5月在石家庄市中医院经手术证实的126例肛瘘病人临床资料,术前均行3.0 T MRI和MSCT检查。根据Parks分类法对比3.0 T MRI和MSCT对肛瘘病人检查的准确率,分析两项联合对肛瘘临床分型的诊断价值。结果3.0 T MRI联合MSCT诊断肛瘘外口的准确率(99.03%)高于MSCT单独诊断(90.29%),联合诊断主瘘管的准确率(100.00%)高于3.0 T MRI、MSCT各自单独诊断(93.65%、91.27%)(P<0.01),联合诊断肛瘘内口、瘘管分支、脓肿与各自单独诊断比较均差异无统计学意义(P>0.05);3.0 T MRI联合MSCT诊断括约肌间型、经括约肌型、括约肌上型、括约肌外型与手术结果的符合率分别为98.48%、100.00%、100.00%、100.00%。结论3.0 T MRI联合MSCT对肛瘘临床分型有良好的诊断价值。

3.0 T磁共振成像及CT在老年低位腰椎间盘突出诊断价值中的对比分析

目的:对比分析3.0 T磁共振成像及CT在老年低位腰椎间盘突出中的诊断价值。方法:选取2021年5月至2023年3月于我院就诊的63例疑似低位腰椎间盘突出患者,以临床最终诊断为金标准,所有患者均行3.0 T磁共振成像及CT检查,观察对比两种检查方式的诊断结果、诊断效能及低位腰椎间盘突出相关影像结果,并对两种检查方式的骨性结果参数进行比较。结果:3.0T磁共振成像的椎间盘变性、脊髓变性、硬膜囊受压检出率高于CT检查(P<0.05),CT的钙化、积气检出率高于3.0 T磁共振成像(P<0.05);3.0 T磁共振成像关节突关节角、腰骶角均高于CT,腰椎曲度、L5S_(1)椎间盘高度低于CT(P<0.05);3.0 T磁共振成像的诊断灵敏度、准确值均高于CT检查,漏诊率低于CT;3.0 T磁共振成像诊断不同类型低位腰椎间盘突出与术后结果的一致性Kappa值高于CT。结论:3.0 T磁共振成像在诊断椎间盘变性、脊髓变性、硬膜囊受压、神经走向中具有明显优势,在诊断钙化、积气中CT检出率更高,因此临床可根据具体情况结合两种检查方式的优点对腰椎间盘突出症进行诊断。

3.0 T盆腔MRI联合增强CT成像在结直肠肿瘤鉴别诊断中的应用价值

目的 探讨3.0 T盆腔磁共振(MRI)联合增强CT成像在结直肠肿瘤诊断中的应用价值,以期为临床制定干预措施提供依据。方法 回顾性分析焦作市人民医院2022年4月至2023年8月收治的138例结直肠肿瘤患者的资料,患者入院后均接受3.0 T盆腔MRI及增强CT成像检查,以病理检查结果为“金标准”,比较3.0 T盆腔MRI、增强CT成像对结直肠肿瘤单独、联合诊断结果、诊断效能,分析其对结直肠肿瘤临床分期诊断结果与病理检查结果一致性。结果 经病理检查结果显示,138例结直肠肿瘤患者中,阳性72例,经3.0 T盆腔MRI检查结果显示,阳性60例,经增强CT成像结果显示,阳性58例,经联合诊断结果显示,阳性71例;3.0 T盆腔MRI、增强CT成像联合检查对结直肠肿瘤诊断灵敏度为94.44%、准确度为94.93%,高于单独3.0 T盆腔MRI(灵敏度80.56%、准确度88.41%)及增强CT成像(灵敏度76.39%、准确度85.51%),漏诊率为5.56%,低于单独3.0 T盆腔MRI漏诊率(19.44%)及增强CT成像漏诊率(23.61%)(P<0.05);3.0 T盆腔MRI、增强CT成像及联合诊断结直肠肿瘤临床分期与病理结果一致性Kappa值分别为0.818、0.772、0.923(P<0.05)。结论 3.0 T盆腔MRI联合增强CT成像可用于结直肠肿瘤诊断中,为临床早期鉴别诊断、评估临床分期提供方案,以制定后续治疗措施,改善预后。

3.0 T MRI动态增强与64层螺旋CT多期扫描诊断肝硬化背景下小肝癌的价值比较

目的比较3.0 T磁共振(MRI)动态增强与64层螺旋CT(64-MDCT)多期扫描对肝硬化背景下小肝癌的诊断价值。方法选择肝硬化合并小肝癌患者55例(66个癌性小结节),分别进行3.0 T MRI动态增强与64-MDCT多期扫描,由两位专家对检查结果进行判定,比较两种检查方法的诊断价值。结果两位观察者通过3.0 T MRI动态增强得到的ROC曲线下面积(AUC)分别为0.893±0.013、0.859±0.027,通过64-MDCT得到的AUC分别为0.657±0.034、0.679±0.026;两位观察者对两种检查方法的诊断价值比较,P均<0.01。两位观察者采用3.0T MRI动态增强诊断肝硬化背景下小肝癌的敏感度、特异度、阴性预测值均高于64-MDCT,P均<0.01。结论 3.0T MRI动态增强对肝硬化背景下小肝癌的诊断价值高于64-MDCT。

肝硬化结节及小肝癌患者3.0T MRI检查结果分析

目的评价3.0 T MRI检查在肝硬化再生性结节(RN)、异型增生性结节(DN)和小肝癌(SHCC)诊断和鉴别诊断中价值。方法回顾性分析经病理检查确诊的69例RN、DN及SHCC患者的3.0 T MRI平扫及容积采集技术(LAVA)三期动态增强扫描特点。结果 RN主要表现为T2WI低信号,动态增强方式呈"缓慢上升型";DN主要表现为T2WI高、低信号,信号较均匀结节的动态方式以"速升缓降型"为主,可有"结中结"(特征表现);SHCC主要表现为T1WI低信号、T2WI高信号,动态增强方式为"速升速降型"。结论肝硬化结节及小肝癌在3.0 T MRI上各有较为典型的表现,临床可据此进行诊断与鉴别诊断;对其他强化类型的肝脏病灶应结合肿瘤血管的扭曲增粗及包膜等表现排除SHCC。

3.0 T HR-MRI评估椎-基底动脉粥样硬化斑块在TIA病情发展中的价值

目的分析3.0 T高分辨率磁共振成像(3.0 T HR-MRI)评估椎-基底动脉粥样硬化斑块稳定性在短暂性脑缺血发作(TIA)的应用价值。方法选取2015年2月至2018年2月期间于本院诊治的TIA患者80例,所有患者均行3.0 T HR-MRI检查出椎-基底动脉粥样硬化斑块,记录椎-基底动脉粥样硬化斑块分布和厚度,并根据斑块稳定性将患者分为斑块稳定组(n=38)和斑块不稳定组(n=42),比较两组患者TIA发作次数以及发作持续时间,门诊随访1年,比较两组患者脑梗死或TIA再发时间、TIA再发次数及脑梗死例数。结果椎-基底动脉粥样硬化斑块最容易在背侧壁形成,斑块厚度以0.5~1.5mm为主;斑块不稳定组患者TIA发作次数显著多于斑块稳定组患者(P<0.05),TIA发作持续时间显著长于斑块稳定组患者(P<0.05);随访1年发现,斑块不稳定组患者脑梗死或TIA再次发作时间显著短于斑块稳定组患者(P<0.05),TIA发作次数、脑梗死例数高于斑块稳定组患者(P<0.05)。结论3.0 T HR-MRI能够评估椎-基底动脉粥样硬化斑块分布、厚度等情况,并对斑块进行定性分析,进一步预测TIA病情发展,为脑血管病二级预防提供更多依据。

3.0T呼吸门控DWI在胰腺癌中的应用研究

目的:在3.0T磁共振上,分析评价呼吸门控DWI序列在胰腺癌中的应用价值。方法:在3.0T磁共振上,15例正常志愿者行常规T1WI、频率饱和脂肪抑制T2WI、MRCP、DWI及LAVE平扫,30例经手术病理证实的胰腺癌患者,术前行常规T1WI、频率饱和脂肪抑制T2WI、MRCP、DWI、三维LAVE及增强三维LAVA扫描,DWI序列基于SE-EPI序列及b值为0和600s/mm2,应用呼吸门控翻转恢复脂肪抑制技术,统计学比较分析正常胰腺胰头、胰体及胰尾的ADC值和胰腺癌、正常胰腺、邻近胰腺及远端炎症区的ADC值。结果:胰腺不同部位的ADC值从大到小依次为胰体、胰尾和胰头,单因素方差分析显示胰腺各部位的ADC值统计学有明显差异,F值为5.521,P<0.05,两两比较显示胰头分别与胰体及胰尾的ADC值有统计学差异,P值分别为0.001及0.023。不同组织的ADC值从低到高依次为胰腺癌、正常胰腺、远端炎症及邻近胰腺组织,单因素方差分析显示不同组织的ADC值有明细统计学差异,F值为15.976,P值为0.000002,两两比较分析显示胰腺癌分别与正常胰腺、邻近胰腺及远端炎症的ADC值统计学有明显差异,P值分别为0.00271、0.000003及0.000105,结论:在3.0T磁共振上,在呼吸门控DWI序列有助于病灶筛查,且测量的ADC值能够较好的反映胰腺癌、正常胰腺、邻近胰腺及远端炎症的组织病理状态。

3.0T磁共振颞颌关节扫描技术的探讨

目的探讨颞颌关节的磁共振(MR)扫描技术及扫描参数。方法 28例受检者行颞颌关节MR检查,分别扫描颞颌关节闭口位和开口位的斜矢状位和斜冠状位,扫描序列包括:T1W-Atse、T2W-TSE、T2-SPAIR、PDWI。结果受检者均能够得到很好的图像,其颞下颌关节的解剖形态显示清晰完整,所有成像序列均能够显示关节盘、关节窝、关节间隙、髁突骨质形态、盘周组织以及翼外肌等。结论 3.0TMR扫描序列及参数的优化组合、病人体位及扫描方位的正确选择均有助于检测引起临床症状或体征的颞颌关节盘及周围组织的解剖与病变损伤情况。

Diffusion kurtosis imaging of microstructural changes in brain tissue affected by acute ischemic stroke in different locations

The location of an acute ischemic stroke is associated with its prognosis. The widely used Gaussian model-based parameter, apparent diffusion coefficient(ADC), cannot reveal microstructural changes in different locations or the degree of infarction. This prospective observational study was reviewed and approved by the Institutional Review Board of Xiamen Second Hospital, China(approval No. 2014002).Diffusion kurtosis imaging(DKI) was used to detect 199 lesions in 156 patients with acute ischemic stroke(61 males and 95 females), mean age 63.15 ± 12.34 years. A total of 199 lesions were located in the periventricular white matter(n = 52), corpus callosum(n = 14), cerebellum(n = 29), basal ganglia and thalamus(n = 21), brainstem(n = 21) and gray-white matter junctions(n = 62). Percentage changes of apparent diffusion coefficient(ΔADC) and DKI-derived indices(fractional anisotropy [ΔFA], mean diffusivity [ΔMD], axial diffusivity [ΔD_a], radial diffusivity ΔDr, mean kurtosis [ΔMK], axial kurtosis [ΔK_a], and radial kurtosis [ΔK_r]) of each lesion were computed relative to the normal contralateral region. The results showed that(1) there was no significant difference in ΔADC, ΔMD, ΔD_a or ΔD_r among almost all locations.(2) There was significant difference in ΔMK among almost all locations(except basal ganglia and thalamus vs. brain stem; basal ganglia and thalamus vs. gray-white matter junctions; and brainstem vs. gray-white matter junctions.(3) The degree of change in diffusional kurtosis in descending order was as follows: corpus callosum > periventricular white matter > brainstem > gray-white matter junctions > basal ganglia and thalamus > cerebellum. In conclusion, DKI could reveal the differences in microstructure changes among various locations affected by acute ischemic stroke, and performed better than diffusivity among all groups.

3.0 T磁共振动态增强及扩散加权成像在浸润性乳腺癌腋窝淋巴结转移诊断中的应用价值

目的探讨应用3.0 T磁共振动态增强(MRI-DCE)及扩散加权成像(DWI)诊断浸润性乳腺癌腋窝淋巴结(ALN)转移的价值。方法我院收治的143例早期浸润性乳腺癌患者,均接受MRI-DCE及DWI评估ALN转移情况,分析两者在ALN转移中诊断价值。结果以病理诊断为金标准,MRI-DCE联合DWI诊断ALN灵敏度、特异度、阳性预测值与阴性预测值分别为94.59%、96.23%、89.74%与98.08%;ALN转移与无ALN转移患者边界、早期强化模式、DWI信号、长径、短径、早期强化率、最大强化率、皮质厚度、表观扩散系数(ADC)值等MRI表现比较,差异有统计学意义(P<0.05);DWI高信号、短径及ADC值是ALN转移的影响因素(P<0.05);DWI信号、短径及ADC值诊断ALN转移曲线下面积(AUC)为0.619、0.745、0.734,各指标联合诊断ALN转移AUC值为0.835。结论3.0 T MR动态增强及扩散加权成像可以有效检出早期浸润性乳腺癌ALN转移,测定DWI信号、短径及ADC值联合有助于提高患者ALN转移诊断价值。