AIM:To determine the optimal b value of diffusionweighted imaging for detecting active inflammation in Crohn's disease.METHODS:Thirty-one patients clinically diagnosed with active Crohn’s disease were referred fo...AIM:To determine the optimal b value of diffusionweighted imaging for detecting active inflammation in Crohn's disease.METHODS:Thirty-one patients clinically diagnosed with active Crohn’s disease were referred for magnetic resonance examination.All patients were scanned on a3.0T magnetic resonance scanner using the same protocol involving four different b values(800,1500,2000and 2500 s/mm2).The diagnostic effect of diffusionweighted imaging was evaluated and compared with endoscopic findings.The diffusion-weighted image quality of four b value groups was evaluated and apparent diffusion coefficient was measured for both nor-mal and inflammatory intestinal segments.RESULTS:The contrast-to-noise ratio and signal-tonoise ratio were not satisfied when b value 2000 or2500 s/mm2 was adopted(36.52±14.95 vs 34.78±24.83,P>0.05;53.58±23.45 vs 47.58±29.67,P>0.05).The qualitative image quality was not enough to meet diagnostic requirement.No matter which b value was chosen,the apparent diffusion coefficient of inflammatory intestinal segments was significantly lower than that of normal intestinal segments(1.38±0.28 vs 2.00±0.38,P<0.01;1.09±0.20 vs 1.50±0.28,P<0.01;0.95±0.19 vs 1.34±0.28,P<0.01;0.88±0.14 vs 1.20±0.21,P<0.01).The lesion detection rate(90.32%),diagnostic sensitivity(81.18%)and specificity(95.10%)would be appropriate when b value 1500 s/mm2 was adopted.CONCLUSION:High b value is suitable for intestinal DW examination on a high field MR scanner.展开更多
目的:探讨3.0 T MR扩散张量成像在颈椎病诊断中的应用效果。方法:从2013年1月开始,至2015年1月结束,一共80例颈椎病患者,采用MR诊断仪对患者进行检查,比较颈椎病患者、健康体检者不同颈髓水平ADC值、FA值、颈髓长轴、前后径、左右径。结...目的:探讨3.0 T MR扩散张量成像在颈椎病诊断中的应用效果。方法:从2013年1月开始,至2015年1月结束,一共80例颈椎病患者,采用MR诊断仪对患者进行检查,比较颈椎病患者、健康体检者不同颈髓水平ADC值、FA值、颈髓长轴、前后径、左右径。结果:(1)在健康体检者中,C2-3、C4-5、C6-7之间ADC值、FA值、颈髓长轴、前后径、左右径无明显差异,无统计学意义,P>0.05;颈髓长轴、前后径、左右径之间两两对比,颈髓长轴值高于前后径和左右径,数据比较差异具有统计学意义,P<0.05。前后径和左右径之间对比,无明显差异,无统计学意义,P>0.05。(2)和对照组对比,A组ADC、FA、a1颈髓长轴无明显差异(P>0.05);a2前后径、a3左右径明显更大(P<0.05)。B组、C组、D组ADC值、FA值、颈髓长轴、前后径、左右径明显更大,数据比较差异明显,存在统计学意义,P<0.05.结论:采用扩散张量成像技术对颈椎病患者进行诊断,能够有效地显示颈椎压迫所致的脊髓微结构变化,具有较高的敏感性,3.0 T MR扩散张量成像在颈椎病诊断中的应用效果显著,能够弥补常规MRI难以定量分析颈椎微结构受压情况的缺点。展开更多
基金Supported by National Basic Research Program of China,No.2012CB932600Shanghai Leading Academic Discipline Project,No.S30203
文摘AIM:To determine the optimal b value of diffusionweighted imaging for detecting active inflammation in Crohn's disease.METHODS:Thirty-one patients clinically diagnosed with active Crohn’s disease were referred for magnetic resonance examination.All patients were scanned on a3.0T magnetic resonance scanner using the same protocol involving four different b values(800,1500,2000and 2500 s/mm2).The diagnostic effect of diffusionweighted imaging was evaluated and compared with endoscopic findings.The diffusion-weighted image quality of four b value groups was evaluated and apparent diffusion coefficient was measured for both nor-mal and inflammatory intestinal segments.RESULTS:The contrast-to-noise ratio and signal-tonoise ratio were not satisfied when b value 2000 or2500 s/mm2 was adopted(36.52±14.95 vs 34.78±24.83,P>0.05;53.58±23.45 vs 47.58±29.67,P>0.05).The qualitative image quality was not enough to meet diagnostic requirement.No matter which b value was chosen,the apparent diffusion coefficient of inflammatory intestinal segments was significantly lower than that of normal intestinal segments(1.38±0.28 vs 2.00±0.38,P<0.01;1.09±0.20 vs 1.50±0.28,P<0.01;0.95±0.19 vs 1.34±0.28,P<0.01;0.88±0.14 vs 1.20±0.21,P<0.01).The lesion detection rate(90.32%),diagnostic sensitivity(81.18%)and specificity(95.10%)would be appropriate when b value 1500 s/mm2 was adopted.CONCLUSION:High b value is suitable for intestinal DW examination on a high field MR scanner.
文摘目的:探讨3.0 T MR扩散张量成像在颈椎病诊断中的应用效果。方法:从2013年1月开始,至2015年1月结束,一共80例颈椎病患者,采用MR诊断仪对患者进行检查,比较颈椎病患者、健康体检者不同颈髓水平ADC值、FA值、颈髓长轴、前后径、左右径。结果:(1)在健康体检者中,C2-3、C4-5、C6-7之间ADC值、FA值、颈髓长轴、前后径、左右径无明显差异,无统计学意义,P>0.05;颈髓长轴、前后径、左右径之间两两对比,颈髓长轴值高于前后径和左右径,数据比较差异具有统计学意义,P<0.05。前后径和左右径之间对比,无明显差异,无统计学意义,P>0.05。(2)和对照组对比,A组ADC、FA、a1颈髓长轴无明显差异(P>0.05);a2前后径、a3左右径明显更大(P<0.05)。B组、C组、D组ADC值、FA值、颈髓长轴、前后径、左右径明显更大,数据比较差异明显,存在统计学意义,P<0.05.结论:采用扩散张量成像技术对颈椎病患者进行诊断,能够有效地显示颈椎压迫所致的脊髓微结构变化,具有较高的敏感性,3.0 T MR扩散张量成像在颈椎病诊断中的应用效果显著,能够弥补常规MRI难以定量分析颈椎微结构受压情况的缺点。
