基于MCM-D工艺的3D-MCM工艺技术研究

基于MCM-D薄膜工艺,开展了3D-MCM相关的无源元件内埋置、芯片减薄、芯片叠层组装、低弧度金丝键合、芯片凸点,以及板级叠层互连装配等工艺技术研究。通过埋置型基板、叠层芯片组装、板级叠层互连,实现了3D-MCM结构,制作出薄膜3D-MCM样品;探索出主要的工艺流程及关键工序控制方法,实现了薄膜3D-MCM封装。

基于Production Module 3D数控铣削仿真技术在钛合金主吊挂加工中的应用

在钛合金主吊挂支架的铣削过程中,采用Production Module 3D软件对数控程序、材料、刀具及工件的综合分析,得到了在整个数控程序下的温度峰值、进给力、切削力及材料去除率等数据。然后采用完善数控程序中的吃刀量、切削速度及进给量来使加工过程中温度、切削力等符合要求,使负载平衡,降低振动。最终刀具的使用寿命提高20%,加工周期降低22%。

3-D MCM封装技术及其应用

介绍了超大规模集成电路(VLSI)用的3-DMCM封装技术的最新发展,重点介绍了3-DMCM封装垂直互连工艺,分析了3-DMCM封装技术的硅效率、复杂程度、热处理、互连密度、系统功率与速度等问题,并对3-DMCM封装的应用作了简要说明。

3-DMCM实用化的进展

介绍了 3- D MCM的四种封装模式的应用实例 ,详细讨论了各种模式的工艺 ,优点及存在的问题。 3-D MCM是未来微电子封装的发展趋势。

3-D MCM 的种类

介绍了3-D MCM封装的种类,其中包括芯片垂直互连和2-D MCM的垂直互连。芯片的垂直互连,包括芯片之间通过周边进行互连,以及芯片之间通过贯穿芯片进行垂直互连(面互连);2-D MCM模块垂直互连,包括2-D MCM之间通过周边进行互连,以及面互连的模式。

Expression analysis of the R2R3-MYB gene family in upland cotton and functional study of GhMYB3D5 in regulating Verticillium wilt resistance

Improving plant resistance to Verticillium wilt(VW),which causes massive losses in Gossypium hirsutum,is a global challenge.Crop plants need to efficiently allocate their limited energy resources to maintain a balance between growth and defense.However,few transcriptional regulators specifically respond to Verticillium dahliae and the underlying mechanism has not been identified in cotton.In this study,we found that the that expression of most R2R3-MYB members in cotton is significantly changed by V.dahliae infection relative to the other MYB types.One novel R2R3-MYB transcription factor(TF)that specifically responds to V.dahliae,GhMYB3D5,was identified.GhMYB3D5 was not expressed in 15 cotton tissues under normal conditions,but it was dramatically induced by V.dahliae stress.We functionally characterized its positive role and underlying mechanism in VW resistance.Upon V.dahliae infection,the up-regulated GhMYB3D5 bound to the GhADH1 promoter and activated GhADH1expression.In addition,GhMYB3D5 physically interacted with GhADH1 and further enhanced the transcriptional activation of GhADH1.Consequently,the transcriptional regulatory module GhMYB3D5-GhADH1 then promoted lignin accumulation by improving the transcriptional levels of genes related to lignin biosynthesis(GhPAL,GhC4H,Gh4CL,and GhPOD/GhLAC)in cotton,thereby enhancing cotton VW resistance.Our results demonstrated that the GhMYB3D5 promotes defense-induced lignin accumulation,which can be regarded as an effective way to orchestrate plant immunity and growth.

Modulation of the thermal transport of micro-structured materials from 3D printing

It is desirable to fabricate materials with adjustable physical properties that can be used in different industrial applications.Since the property of a material is highly dependent on its inner structure,the understanding of structure–property correlation is critical to the design of engineering materials.3D printing appears as a mature method to effectively produce micro-structured materials.In this work,we created different stainless-steel microstructures by adjusting the speed of 3D printing and studied the relationship between thermal property and printing speed.Our microstructure study demonstrates that highly porous structures appear at higher speeds,and there is a nearly linear relationship between porosity and printing speed.The thermal conductivity of samples fabricated by different printing speeds is characterized.Then,the correlation between porosity,thermal conductivity,and scanning speed is established.Based on this correlation,the thermal conductivity of a sample can be predicted from its printing speed.We fabricated a new sample at a different speed,and the thermal conductivity measurement agrees well with the value predicted from the correlation.To explore thermal transport physics,the effects of pore structure and temperature on the thermal performance of the printed block are also studied.Our work demonstrates that the combination of the 3D printing technique and the printing speed control can regulate the thermophysical properties of materials.

当代高密度电子组装新技术──SMT，MCM，WSI，3D

当代高密度电子组装新技术──ＳＭＴ，ＭＣＭ，ＷＳＩ，３Ｄ电子工业部第十四研究所王宝善将成熟的电气原理图转变成为适用的可生产的电子硬件的技术过程称为电子组装技术。随着电子学／微电子学、半导体／集成电路、计算机／ＣＡＤ／ＣＡＴ／ＣＡＭ／ＥＤＡ、电子材料等...

Fe_3O_4@MCM-48–SO_3H:合成苯并[f]色烯并[2,3-d]嘧啶酮的高效、可磁性分离纳米催化剂(英文)

Sulfonic acid groups were grafted onto three different types of synthesized magnetic nanoparticles, namely Fe3O4, Fe3O4@SiO2, and Fe3O4@MCM-48. The sulfonic acid-functionalized nanoparticles were evaluated as catalysts for the synthesis of 5-aryl-1H-benzo[f]chromeno[2,3-d]pyrimidine-2,4(3H,5H)-dione derivatives in terms of activity and recyclability. Their catalytic activities were compared with that of the homogeneous acid catalyst 1-methylimidazolium hydrogen sulfate([HMIm][HSO4]). The activity of Fe3O4@MCM-48–SO3H was comparable to those of the other heter-ogeneous and homogeneous catalysts.

Modulation Effects of the 3D Strain Microenvironment on Characteristics of Mesenchymal Stem Cell-Derived Exosomes

It is necessary to investigate the characteristics of Mesenchymal stem cells(MSCs)derived exosomes,and especially their application in tissue regeneration.Previous studies have shown that inflammatory stimulation enhanced the secretion of MSC-derived exosomes with stronger anti-inflammatory protein,cytokine profiles,and functional RNA via altering COX2/PGE2 pathway.Recently,accumulating evidence has also revealed that biophysical cues(especially biomechanical cues)in cell microenvironment have significant effects not only on cells but also on their exosomes.It has been reported that applying bi-axial strain to MSCs induces formation of a stiffer cytoskeleton through mTORC2 signaling,which biases against adipogenic differentiation and toward osteoblastogenesis.At the same time,For example,dimensionality,composition and stiffness of the extracellular matrix(ECM)has been proved to affect the size and composition of exosomes secreted by cancer cells.However,the effects of biomechanical cues in the three-dimensional(3D)microenvironment on stem cell-derived exosomes remains to be unveiled.Therefore,it is important to understand the roles of 3D cell mechanical microenvironment in regulating the characteristics of stem cell-derived exosomes and develop more efficient approaches to enhance their functions.This study aimed to explore the changes in characteristics of exosomes secreted by MSCs in periodontium in response to the matrix strain in 3D.Periodontal ligament stem cells(PDLSCs)were cultured in a 3D strain microenvironment engineered with microscale magnetically stretched collagen hydrogels.The morphology,particle distribution,marker protein expression of PDLSC-derived exosomes were analyzed.Then the pro-osteogenic property of exosomes was evaluated by assessing cell viability,proliferation,migration and osteogenic differentiation of target cells,for instance human bone marrow mesenchymal stem cells(hBMSCs).Detailed characterizations revealed that PDLSC-derived exosomes in the 3D strain mi-croenvironment were with similar morphology,particle distribution and surface markers.Notably,Exosomes secreted by PDLSCs in strain microenvironment were more endocytosed by hBMSCs and were more potent in improving proliferation and migration of hBMSCs,comparing with PDLSCs in non-strain environment.Alizarin red staining and molecular biology experiments confirmed that treatment of exosomes secreted by PDLSCs under mechanical stimulation led to a significant increase in osteogenic differentiation of hBMSCs in vitro.Meanwhile,in vivo study also indicated that PDLSC-derived exosomes obtained from the 3D strain microenvironment could obviously promote new bone formation.Our findings revealed that mechanical cues profoundly affected the characteristics of PDLSC-derived exosomes,especially for their bio-activity,providing a foundation for using the 3D mechanical microenvironment to enhance the osteo-inductive functions of stem cell-derived exosomes in cell-free therapy for bone regeneration.

Electronic structure modulation with ultrafine Fe_(3)O_(4) nanoparticles on 2D Ni-based metal-organic framework layers for enhanced oxygen evolution reaction

Two-dimensional(2D)metal organic frameworks(MOFs)are emerging as low-cost oxygen evolution reaction(OER)electrocatalysts,however,suffering aggregation and poor operation stability.Herein,ultrafine Fe_(3)O_(4) nanoparticles(diameter:6±2 nm)are homogeneously immobilized on 2D Ni based MOFs(Ni-BDC,thickness:5±1 nm)to improve the OER stability.Electronic structure modulation for enhanced catalytic activity is studied via adjusting the amount of Fe_(3)O_(4) nanoparticles on Ni-BDC.The optimal Fe_(3)O_(4)/Ni-BDC achieves the best OER performance with an overpotential of 295 mV at 10 mA cm^(-2),a Tafel slope of 47.8 mV dec^(-1) and a considerable catalytic durability of more than 40 h(less than 5 h for Ni-BDC alone).DFT calculations confirm that the active sites for Fe_(3)O_(4)/Ni-BDC are mainly contributed by Fe species with a higher oxidation state,and the potential-determining step(PDS)is the formation of the adsorbed O*species,which are facilitated in the composite.

CVD Diamond Sink Application in High Power 3D MCMs

As electronic packages become more compact, run at faster speeds and dissipate more heat, package designers need more effective thermal management materials. CVD diamond, because of its high thermal conductivity, low dielectric loss and its great mechanical strength, is an excellent material for three dimensional （319） multichip modules （MCMs） in the next generation compact high speed computers and high power microwave components. In this paper, we have synthesized a large area freestanding diamond films and substrates, and polished diamond substrates, which make MCMs diamond film sink becomes a reality.

高密度多层基板3D—MCM的结构与工艺制作

本文以一种具有系统级功能的信号处理电路为例。介绍多层MCM基板层间通过焊球垂直互连的3D—MCM结构设计和工艺制作，该型3D—MCM模块的元器件封装效率超过200％，在与I／O端子（PGA引线、BGA焊球）一体化封装的3层LTCC基板的表面上及其腔体内组装了432只外贴元器件，封装外形尺寸仅为32mm×32mm×15mm。

三维(3-D)封装技术

3 -D多芯片组件 (MCM)是未来微电子封装的发展趋势。本文介绍了超大规模集成(VLSI)用的 3-D封装技术的最新进展 ,详细报导了垂直互连技术 ,概括讨论了选择 3-D叠层技术的一些关键问题 ,并对 3-D封装和 2

用脉宽调制制造多级3—D计算全息图

总结了用脉宽调制制造多级3-D计算全息图的方法、原理,给出了实验步骤和框图。

Evaluation of 3-D Printed Immobilisation Shells for Head and Neck IMRT

This paper presents the preclinical evaluation of a novel immobilization system for patients undergoing external beam radiation treatment of head and neck tumors. An immobilization mask is manufactured directly from a 3-D model, built using the CT data routinely acquired for treatment planning so there is no need to take plaster of Paris moulds. Research suggests that many patients find the mould room visit distressing and so rapid prototyping could potentially improve the overall patient experience. Evaluation of a computer model of the immobilization system using an anthropomorphic phantom shows that >99% of vertices are within a tolerance of ±0.2 mm. Hausdorff distance was used to analyze CT slices obtained by rescanning the phantom with a printed mask in position. These results show that for >80% of the slices the median “worse-case” tolerance is approximately 4 mm. These measurements suggest that printed masks can achieve similar levels of immobilization to those of systems currently in clinical use.

Dye-sensitized solar cell module realized photovoltaic and photothermal highly efficient conversion via three-dimensional printing technology

Three-dimensional （3D） printing technology is employed to improve the photovoltaic and photothermal conversion efficiency of dye-sensitized solar cell （DSC） module. The 3D-printed concentrator is optically designed and improves the photovoltaic efficiency of the DSC module from 5.48% to 7.03%. Additionally, with the 3D-printed microfluidic device serving as water cooling, the temperature of the DSC can be effectively controlled, which is beneficial for keeping a high photovoltaic conversion efficiency for DSC module. Moreover, the 3D-printed microfluidic device can realize photothermal conversion with an instantaneous photothermal efficiency of 42.1%. The integrated device realizes a total photovoltaic and photothermal conversion efficiency of 49% at the optimal working condition.

3D Vehicle Detection Algorithm Based onMultimodal Decision-Level Fusion

3D vehicle detection based on LiDAR-camera fusion is becoming an emerging research topic in autonomous driving.The algorithm based on the Camera-LiDAR object candidate fusion method(CLOCs)is currently considered to be a more effective decision-level fusion algorithm,but it does not fully utilize the extracted features of 3D and 2D.Therefore,we proposed a 3D vehicle detection algorithm based onmultimodal decision-level fusion.First,project the anchor point of the 3D detection bounding box into the 2D image,calculate the distance between 2D and 3D anchor points,and use this distance as a new fusion feature to enhance the feature redundancy of the network.Subsequently,add an attention module:squeeze-and-excitation networks,weight each feature channel to enhance the important features of the network,and suppress useless features.The experimental results show that the mean average precision of the algorithm in the KITTI dataset is 82.96%,which outperforms previous state-ofthe-art multimodal fusion-based methods,and the average accuracy in the Easy,Moderate and Hard evaluation indicators reaches 88.96%,82.60%,and 77.31%,respectively,which are higher compared to the original CLOCs model by 1.02%,2.29%,and 0.41%,respectively.Compared with the original CLOCs algorithm,our algorithm has higher accuracy and better performance in 3D vehicle detection.

Pulse modulated microwave and infrared thermography for superficial hyperthermia

A 3D temperature field distribution of biological tissue for superficial hyperthermia using a pulse modulated microwave （PMMW） was presented. A 3D sliced homogeneous phantom was radiated by the PMMW and an infrared thermal imager was applied to image temperature distribution throughout the phantom. The period of the PMMW is 3 s and the output power is 35 W. The temperature rises by at least 3 ℃ in the phantom when the duty cycle varies from 1/3, 1/2, 2/3 to 1 （denoted by scenarios 1-4）. Both the accumulative temperature-volume histogram and the relative depth-area ratio histogram show that the maximum temperature rise （MTR） is 6.6 and 8 ℃ in scenarios 2 and 3, and they are superior to scenarios 1 and 4. Furthermore, the PMMW can control temperature field distribution of biological tissue. It provides both preliminary basis for thermal volume control and new technology for temperature control and monitor in superficial hyperthermia.