目的:研制一种主要用于3T胎儿磁共振检查时噪声安全防护的设备。方法:预实验使用隔音棉、单层玻璃罩、真空双层罩3种不同的隔音手段,在静音室测量对同一噪声的衰减效果。其中隔音棉直接包裹分贝仪,单层玻璃罩和真空双层罩则将分贝仪...目的:研制一种主要用于3T胎儿磁共振检查时噪声安全防护的设备。方法:预实验使用隔音棉、单层玻璃罩、真空双层罩3种不同的隔音手段,在静音室测量对同一噪声的衰减效果。其中隔音棉直接包裹分贝仪,单层玻璃罩和真空双层罩则将分贝仪置于其中,入口用隔音棉封闭。根据预实验的降噪效果,选择真空双层罩进入磁共振室进行不同序列的降噪测试。结果:静音室中隔音棉、单层玻璃罩、真空双层罩3种隔音手段的降噪幅度分别为3.5、4.1、9.4 d B(A);在磁共振室中使用真空双层罩以后,不同磁共振序列降噪以后的噪声幅值范围为84.4~104.2 d B(A),降噪幅度范围为15.5~26.9 d B(A)。结论:真空双层罩能够将大部分3T磁共振序列的噪声降到安全阈值以下,能方便地给胎儿磁共振提供噪声安全防护。展开更多
脑功能磁共振成像可以无创伤地观察人脑内部各个脑区的变化。3T高场磁共振成像设备信噪比更佳,提供的信息更详尽以及空间分辨率更高,目前正逐渐在国内外推广使用。SPM5是现今最流行的功能磁共振成像(functional Magnetic Resonance Imag...脑功能磁共振成像可以无创伤地观察人脑内部各个脑区的变化。3T高场磁共振成像设备信噪比更佳,提供的信息更详尽以及空间分辨率更高,目前正逐渐在国内外推广使用。SPM5是现今最流行的功能磁共振成像(functional Magnetic Resonance Imaging,fMR I)数据处理软件。文章基于SPM5数据处理软件对3T高场功能磁共振成像设备所获取的视觉刺激实验数据进行分析处理,实验结果更清晰、更直观、更精确地反映了相应脑区的变化。展开更多
Objective Io evaluate changes in morphology of the cesarean scar and uterus between one and two years after cesarean section using high-resolution,three dimensional T2-weighted sampling perfection with application opt...Objective Io evaluate changes in morphology of the cesarean scar and uterus between one and two years after cesarean section using high-resolution,three dimensional T2-weighted sampling perfection with application optimized contrast using diflerent flip angle evolutions Magnetic Resonance Imaging(3DT2w SPACE MRI).Methods This prospective study was performed to investigate morphological changes in the cesarean scars and uterus from one to two years after cesarean section using high-resolution,3D T2w SPACE MRI.The healthy volunteers having no childbearing history were recruited as the controls.All data were measured by two experienced radiologists.All data with normal distribution between the one-year and two-year groups were compared using a paired-sample t test or independent t test.Results Finally,46 women took a pelvic MR examination one year after cesarean section,and a subset of 15 completed the same examination again after two years of cesarean section.Both the uterine length and the anterior wall thickness after two years of cesarean section(5.75±0.46 and 1.45±0.35 cm)were significantly greater than those measured at one year(5.33±0.59 and 1.25±0.27 cm)(t=-2.363 and-2.175,P=0.033 and 0.048).No significant difference was shown in myometrial thickness two years after cesarean section(1.45±0.35 cm)with respect to the control group(1.58±0.21 cm,P=0.170).Nine women who underwent MRI twice were considered to have scar diverticula one year after cesarean section,and still had diverticula two years after cesarean section.The thickness,height,and width of the uterine scar showed no significant change from one to two years(all P>0.05).Conclusions 3D T2w SPACE MRI provides overall morphologic details and shows dynamic changes in the scar and the uterus between one and two years after cesarean section.Scar morphology after cesarean section reached relatively stable one year after cesarean section,and uterine morphology was closer to normal two years after cesarean section.展开更多
目的动态对比增强磁共振成像(dynamic contrast enhanced magnetic resonance imaging,DCE-MRI)是一种新的用来评估组织血管性质的功能磁共振成像方法。文中旨在探讨DCE-MRI在血管渗透性层面反映肝癌组织的血管生成情况,从而为肝癌的评...目的动态对比增强磁共振成像(dynamic contrast enhanced magnetic resonance imaging,DCE-MRI)是一种新的用来评估组织血管性质的功能磁共振成像方法。文中旨在探讨DCE-MRI在血管渗透性层面反映肝癌组织的血管生成情况,从而为肝癌的评估提供更客观的诊断信息。方法对21例临床或病理诊断为原发性肝癌的患者进行DCE-MRI,按选取位置不同将感兴趣区分为整个肿瘤、肿瘤热点和肿瘤周围肝组织3组。应用Tissue 4D软件包对DCE-MRI图像进行后处理,得到下列定量参数:转运常数(Ktrans)、速率常数(Kep)、肿瘤血管外细胞外间隙体积分数(Ve)及半定量参数对比剂浓度-时间曲线下初始面积(initial area under the contrast concentration versus time curve,iAUC)。结果肿瘤周围肝组织的平均Ktrans、Kep、Ve及iAUC分别为(0.124±0.057)/min、(0.632±0.158)/min、(0.205±0.098)和(10.009±6.201),整个肿瘤分别为(0.196±0.109)/min、(0.546±0.214)/min、(0.424±0.160)和(13.675±6.113),肿瘤热点分别为(0.422±0.170)/min、(0.780±0.308)/min、(0.589±0.116)和(35.663±19.086)。肿瘤热点各项参数均高于整个肿瘤,差异均具有统计学意义(P<0.05);整个肿瘤的Ktrans、Ve及iAUC值均高于肿瘤周围肝组织,2组间Ktrans、Ve差异具有统计学意义(P<0.05);肿瘤周围肝组织的各项参数均明显低于肿瘤热点,除Kep外差异均具有统计学意义(P<0.05)。结论应用DCE-MRI参数分析组织微血管的渗透性,间接反映肿瘤血管的生成情况,对原发性肝癌的评估有一定的帮助。监测肿瘤热点的各项DCE-MRI参数,对原发性肝癌的评估可能会更加准确。展开更多
目的评价MRI 3D T2-SPACE诊断大脑中动脉及基底动脉狭窄的价值。方法选取2019年11月至2020年10月在南京医科大学附属淮安第一医院就诊的40例脑血管狭窄患者为研究对象,选取符合研究要求的大脑中动脉及基底动脉共120根。在入院1周内完成...目的评价MRI 3D T2-SPACE诊断大脑中动脉及基底动脉狭窄的价值。方法选取2019年11月至2020年10月在南京医科大学附属淮安第一医院就诊的40例脑血管狭窄患者为研究对象,选取符合研究要求的大脑中动脉及基底动脉共120根。在入院1周内完成颅颈动脉MRI 3D T2-SPACE和数字减影血管造影(DSA)检查,分别评估动脉狭窄程度。按狭窄程度分成轻度(1%~49%)、中度(50%~69%)、重度(70%~99%)和闭塞(100%),和金标准DSA检查对照,计算灵敏度、特异度,并分析MRI 3D T2-SPACE和DSA诊断结果的一致性。结果MRI 3D T2-SPACE诊断大脑中动脉及基底动脉狭窄/闭塞的灵敏度、特异度结果如下,轻度狭窄分别为90.0%、96.4%,中度狭窄分别为77.8%、98.2%,重度狭窄分别为96.7%、97.8%,闭塞分别为87.5%、100.0%。MRI 3D T2-SPACE与DSA检查诊断大脑中动脉及基底动脉轻、中、重度狭窄及闭塞的一致性分别为0.760、0.760、0.934、0.929。结论MRI 3D T2-SPACE能够较准确地评估大脑中动脉及基底动脉狭窄程度,特别是对重度狭窄及闭塞的诊断与DSA检查结果高度一致,作为血管检查的一种全新技术,其将会在临床发挥重要作用。展开更多
文摘目的:研制一种主要用于3T胎儿磁共振检查时噪声安全防护的设备。方法:预实验使用隔音棉、单层玻璃罩、真空双层罩3种不同的隔音手段,在静音室测量对同一噪声的衰减效果。其中隔音棉直接包裹分贝仪,单层玻璃罩和真空双层罩则将分贝仪置于其中,入口用隔音棉封闭。根据预实验的降噪效果,选择真空双层罩进入磁共振室进行不同序列的降噪测试。结果:静音室中隔音棉、单层玻璃罩、真空双层罩3种隔音手段的降噪幅度分别为3.5、4.1、9.4 d B(A);在磁共振室中使用真空双层罩以后,不同磁共振序列降噪以后的噪声幅值范围为84.4~104.2 d B(A),降噪幅度范围为15.5~26.9 d B(A)。结论:真空双层罩能够将大部分3T磁共振序列的噪声降到安全阈值以下,能方便地给胎儿磁共振提供噪声安全防护。
文摘脑功能磁共振成像可以无创伤地观察人脑内部各个脑区的变化。3T高场磁共振成像设备信噪比更佳,提供的信息更详尽以及空间分辨率更高,目前正逐渐在国内外推广使用。SPM5是现今最流行的功能磁共振成像(functional Magnetic Resonance Imaging,fMR I)数据处理软件。文章基于SPM5数据处理软件对3T高场功能磁共振成像设备所获取的视觉刺激实验数据进行分析处理,实验结果更清晰、更直观、更精确地反映了相应脑区的变化。
文摘Objective Io evaluate changes in morphology of the cesarean scar and uterus between one and two years after cesarean section using high-resolution,three dimensional T2-weighted sampling perfection with application optimized contrast using diflerent flip angle evolutions Magnetic Resonance Imaging(3DT2w SPACE MRI).Methods This prospective study was performed to investigate morphological changes in the cesarean scars and uterus from one to two years after cesarean section using high-resolution,3D T2w SPACE MRI.The healthy volunteers having no childbearing history were recruited as the controls.All data were measured by two experienced radiologists.All data with normal distribution between the one-year and two-year groups were compared using a paired-sample t test or independent t test.Results Finally,46 women took a pelvic MR examination one year after cesarean section,and a subset of 15 completed the same examination again after two years of cesarean section.Both the uterine length and the anterior wall thickness after two years of cesarean section(5.75±0.46 and 1.45±0.35 cm)were significantly greater than those measured at one year(5.33±0.59 and 1.25±0.27 cm)(t=-2.363 and-2.175,P=0.033 and 0.048).No significant difference was shown in myometrial thickness two years after cesarean section(1.45±0.35 cm)with respect to the control group(1.58±0.21 cm,P=0.170).Nine women who underwent MRI twice were considered to have scar diverticula one year after cesarean section,and still had diverticula two years after cesarean section.The thickness,height,and width of the uterine scar showed no significant change from one to two years(all P>0.05).Conclusions 3D T2w SPACE MRI provides overall morphologic details and shows dynamic changes in the scar and the uterus between one and two years after cesarean section.Scar morphology after cesarean section reached relatively stable one year after cesarean section,and uterine morphology was closer to normal two years after cesarean section.
文摘目的动态对比增强磁共振成像(dynamic contrast enhanced magnetic resonance imaging,DCE-MRI)是一种新的用来评估组织血管性质的功能磁共振成像方法。文中旨在探讨DCE-MRI在血管渗透性层面反映肝癌组织的血管生成情况,从而为肝癌的评估提供更客观的诊断信息。方法对21例临床或病理诊断为原发性肝癌的患者进行DCE-MRI,按选取位置不同将感兴趣区分为整个肿瘤、肿瘤热点和肿瘤周围肝组织3组。应用Tissue 4D软件包对DCE-MRI图像进行后处理,得到下列定量参数:转运常数(Ktrans)、速率常数(Kep)、肿瘤血管外细胞外间隙体积分数(Ve)及半定量参数对比剂浓度-时间曲线下初始面积(initial area under the contrast concentration versus time curve,iAUC)。结果肿瘤周围肝组织的平均Ktrans、Kep、Ve及iAUC分别为(0.124±0.057)/min、(0.632±0.158)/min、(0.205±0.098)和(10.009±6.201),整个肿瘤分别为(0.196±0.109)/min、(0.546±0.214)/min、(0.424±0.160)和(13.675±6.113),肿瘤热点分别为(0.422±0.170)/min、(0.780±0.308)/min、(0.589±0.116)和(35.663±19.086)。肿瘤热点各项参数均高于整个肿瘤,差异均具有统计学意义(P<0.05);整个肿瘤的Ktrans、Ve及iAUC值均高于肿瘤周围肝组织,2组间Ktrans、Ve差异具有统计学意义(P<0.05);肿瘤周围肝组织的各项参数均明显低于肿瘤热点,除Kep外差异均具有统计学意义(P<0.05)。结论应用DCE-MRI参数分析组织微血管的渗透性,间接反映肿瘤血管的生成情况,对原发性肝癌的评估有一定的帮助。监测肿瘤热点的各项DCE-MRI参数,对原发性肝癌的评估可能会更加准确。
文摘目的评价MRI 3D T2-SPACE诊断大脑中动脉及基底动脉狭窄的价值。方法选取2019年11月至2020年10月在南京医科大学附属淮安第一医院就诊的40例脑血管狭窄患者为研究对象,选取符合研究要求的大脑中动脉及基底动脉共120根。在入院1周内完成颅颈动脉MRI 3D T2-SPACE和数字减影血管造影(DSA)检查,分别评估动脉狭窄程度。按狭窄程度分成轻度(1%~49%)、中度(50%~69%)、重度(70%~99%)和闭塞(100%),和金标准DSA检查对照,计算灵敏度、特异度,并分析MRI 3D T2-SPACE和DSA诊断结果的一致性。结果MRI 3D T2-SPACE诊断大脑中动脉及基底动脉狭窄/闭塞的灵敏度、特异度结果如下,轻度狭窄分别为90.0%、96.4%,中度狭窄分别为77.8%、98.2%,重度狭窄分别为96.7%、97.8%,闭塞分别为87.5%、100.0%。MRI 3D T2-SPACE与DSA检查诊断大脑中动脉及基底动脉轻、中、重度狭窄及闭塞的一致性分别为0.760、0.760、0.934、0.929。结论MRI 3D T2-SPACE能够较准确地评估大脑中动脉及基底动脉狭窄程度,特别是对重度狭窄及闭塞的诊断与DSA检查结果高度一致,作为血管检查的一种全新技术,其将会在临床发挥重要作用。