A newly synthesized reagent 2-amino-5-mercapto-[1, 3, 4]triazole (MATZ) has been usedto fabricate self-assembled monolayers (SAMs) on gold electrode for the first time. The SAMselectrode was characterized by electroch...A newly synthesized reagent 2-amino-5-mercapto-[1, 3, 4]triazole (MATZ) has been usedto fabricate self-assembled monolayers (SAMs) on gold electrode for the first time. The SAMselectrode was characterized by electrochemical methods and scanning electronic microscopy (SEM),the SAMs electrode can be used to determinate dopamine (DA) and uric acid (UA) simultaneouslywith a detection limit of 8×10-7 mol/L for DA and 1×10-6 mol/L for UA respectively. The SAMscan also be used to detect the contents of DA and UA in synthetic urine sample with satisfactoryresults.展开更多
Dimethyl-1-(1, 2, 4-triazol) -2- butanone was treated with aqueous formaldehyde to give an additional product, and subsequent elimination by acetic anhydride yielded 4, 4-dimethyl-2-(1, 2, 4-triazol)-1-penten-3-one. ...Dimethyl-1-(1, 2, 4-triazol) -2- butanone was treated with aqueous formaldehyde to give an additional product, and subsequent elimination by acetic anhydride yielded 4, 4-dimethyl-2-(1, 2, 4-triazol)-1-penten-3-one. Further addition with substituted amines provided a series of (1, 2, 4-triazol)-4, 4-dimethyl-3-pentanone, which were then reduced by KBH4 to obtain a series of (1, 2, 4-triazol)-4, 4-dimethyl-3-pentanol. Their structures were confirmed by 1HNMR and elemental analysis. The results of bioassay showed that the title products possess good fungicidal activities.展开更多
A new Cu(Ⅱ) complex,[Cu_(4)Cl_(6)O(1-TrTz)_(4)]where 1-TrTz is 1-trityl-1H-[1,2,4]triazole,was synthesized by the reaction of 1-trityl-1H-[1,2,4]triazole with two hydrated cupric chlorides,and its structure was chara...A new Cu(Ⅱ) complex,[Cu_(4)Cl_(6)O(1-TrTz)_(4)]where 1-TrTz is 1-trityl-1H-[1,2,4]triazole,was synthesized by the reaction of 1-trityl-1H-[1,2,4]triazole with two hydrated cupric chlorides,and its structure was characterized by X-ray single-crystal diffraction.[Cu4Cl6O(1-TrTz)4]is of monoclinic system,space group P21/c,a=12.5024(13),b=26.400(3),c=28.588(3)A,β=112.807(4)°,V=8698.1(16)A^(3),Z=4,ρcalc=1.411 g/cm^(3),μ=1.265 mm^(–1),F(000)=3772,the final R=0.1293 and w R=0.3644 for 55774 observed reflections (I>2s(I)),R(all data)=0.1972,w R(all data)=0.3989,completeness to theta of 25.242 is 99.9%and GOF=1.103.In the structure of[Cu_(4)Cl_(6)O(1-TrTz)_(4)],the central O atom is tetrahedral and is coordinated with four Cu atoms.The distance between copper and oxygen bond is 1.909(6)A.In addition,the catalytic property of this complex was investigated and it could effectively catalyze the Ullmann coupling reaction of various (hetero)aryl chlorides with azoles.展开更多
文摘A newly synthesized reagent 2-amino-5-mercapto-[1, 3, 4]triazole (MATZ) has been usedto fabricate self-assembled monolayers (SAMs) on gold electrode for the first time. The SAMselectrode was characterized by electrochemical methods and scanning electronic microscopy (SEM),the SAMs electrode can be used to determinate dopamine (DA) and uric acid (UA) simultaneouslywith a detection limit of 8×10-7 mol/L for DA and 1×10-6 mol/L for UA respectively. The SAMscan also be used to detect the contents of DA and UA in synthetic urine sample with satisfactoryresults.
文摘Dimethyl-1-(1, 2, 4-triazol) -2- butanone was treated with aqueous formaldehyde to give an additional product, and subsequent elimination by acetic anhydride yielded 4, 4-dimethyl-2-(1, 2, 4-triazol)-1-penten-3-one. Further addition with substituted amines provided a series of (1, 2, 4-triazol)-4, 4-dimethyl-3-pentanone, which were then reduced by KBH4 to obtain a series of (1, 2, 4-triazol)-4, 4-dimethyl-3-pentanol. Their structures were confirmed by 1HNMR and elemental analysis. The results of bioassay showed that the title products possess good fungicidal activities.
基金Supported by the Natural Science Foundation of Tianjin (No.16JCYBJC19700)the National Natural Science Foundation of China (No.21771138)。
文摘A new Cu(Ⅱ) complex,[Cu_(4)Cl_(6)O(1-TrTz)_(4)]where 1-TrTz is 1-trityl-1H-[1,2,4]triazole,was synthesized by the reaction of 1-trityl-1H-[1,2,4]triazole with two hydrated cupric chlorides,and its structure was characterized by X-ray single-crystal diffraction.[Cu4Cl6O(1-TrTz)4]is of monoclinic system,space group P21/c,a=12.5024(13),b=26.400(3),c=28.588(3)A,β=112.807(4)°,V=8698.1(16)A^(3),Z=4,ρcalc=1.411 g/cm^(3),μ=1.265 mm^(–1),F(000)=3772,the final R=0.1293 and w R=0.3644 for 55774 observed reflections (I>2s(I)),R(all data)=0.1972,w R(all data)=0.3989,completeness to theta of 25.242 is 99.9%and GOF=1.103.In the structure of[Cu_(4)Cl_(6)O(1-TrTz)_(4)],the central O atom is tetrahedral and is coordinated with four Cu atoms.The distance between copper and oxygen bond is 1.909(6)A.In addition,the catalytic property of this complex was investigated and it could effectively catalyze the Ullmann coupling reaction of various (hetero)aryl chlorides with azoles.
