A nanosolid heteropoly acid of H 3PW 12 O 40 /SiO 2 was prepared with the sol-gel method and used to catalyze sythesis of methyl 5-amino-1,2,4,-trazolylformate sulfate.The structure of the nanosolid heteropoly acid H ...A nanosolid heteropoly acid of H 3PW 12 O 40 /SiO 2 was prepared with the sol-gel method and used to catalyze sythesis of methyl 5-amino-1,2,4,-trazolylformate sulfate.The structure of the nanosolid heteropoly acid H 3PW 12 O 40 /SiO 2 was characterized by IR,XRD and TEM.The following optimum condition were that the mole ratio of alcohol to carboxylic acid is 27∶1,the temperature is 75℃,the reaction time is 5 hours,and the catalyst is 2 5% of feedstock.Under the optimum conditions,the yield of esters was above 94%.展开更多
1H1,2,4-triazole derivatives,owing to their extensive uses in pharmaceutical synthesis, four 5substituted1H1,2,4triazoles were prepared with 5amino1H1,2,4triazole3carboxylic acid through diazotiz...1H1,2,4-triazole derivatives,owing to their extensive uses in pharmaceutical synthesis, four 5substituted1H1,2,4triazoles were prepared with 5amino1H1,2,4triazole3carboxylic acid through diazotization and Sandmeyer reaction.Their structures were characterized by IR,UV,1H NMR and MS.展开更多
文摘A nanosolid heteropoly acid of H 3PW 12 O 40 /SiO 2 was prepared with the sol-gel method and used to catalyze sythesis of methyl 5-amino-1,2,4,-trazolylformate sulfate.The structure of the nanosolid heteropoly acid H 3PW 12 O 40 /SiO 2 was characterized by IR,XRD and TEM.The following optimum condition were that the mole ratio of alcohol to carboxylic acid is 27∶1,the temperature is 75℃,the reaction time is 5 hours,and the catalyst is 2 5% of feedstock.Under the optimum conditions,the yield of esters was above 94%.
文摘1H1,2,4-triazole derivatives,owing to their extensive uses in pharmaceutical synthesis, four 5substituted1H1,2,4triazoles were prepared with 5amino1H1,2,4triazole3carboxylic acid through diazotization and Sandmeyer reaction.Their structures were characterized by IR,UV,1H NMR and MS.
