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Dynamic fracture of Ti-6Al-4V alloy in Taylor impact test 被引量:4
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作者 任宇 谭成文 +1 位作者 张静 王富耻 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2011年第2期223-235,共13页
The dynamic fracture behaviors of Ti-6Al-4V alloy at high strain rate loading were investigated systemically through Taylor impact test, over the range of impact velocities from 145 m/s to 306 m/s. The critical impact... The dynamic fracture behaviors of Ti-6Al-4V alloy at high strain rate loading were investigated systemically through Taylor impact test, over the range of impact velocities from 145 m/s to 306 m/s. The critical impact velocity of fracture ranges from 217 m/s to 236 m/s. Smooth surfaces and ductile dimple areas were observed on the fracture surfaces. As the impact velocity reached 260 m/s, the serious melting regions were also observed on the fracture surfaces. Self-organization of cracks emerges when the impact velocity reaches 260 m/s, while some special cracks whose "tips" are not sharp but arc and smooth, and without any evidence of deformation or adiabatic shear band were also observed on the impact end surfaces. Examination of the sections of these special cracks reveals that the cracks expand along the two maximum shear stress directions respectively, and finally intersect as a tridimensional "stagger ridge" structure. 展开更多
关键词 Ti-6Al-4V alloy dynamic fracture behavior adiabatic shear band Taylor impact test
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(1-3)-β-D葡聚糖联合降钙素原、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究
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作者 黄强 王宇 +5 位作者 江渊 梁道斌 黄锐洁 秦小超 潘燕妮 和鹰 《中国真菌学杂志》 CSCD 2024年第1期21-24,29,共5页
目的探讨(1-3)-β-D葡聚糖联合降钙素原(procalcitonin,PCT)、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究。方法回顾性选取我院2020年1月—2022年6月住院的120例艾滋病患者为研究对象。依据实验室结果,将... 目的探讨(1-3)-β-D葡聚糖联合降钙素原(procalcitonin,PCT)、CD4^(+)T淋巴细胞多指标在艾滋病患者马尔尼菲篮状菌感染早期诊断临床研究。方法回顾性选取我院2020年1月—2022年6月住院的120例艾滋病患者为研究对象。依据实验室结果,将其分为马尔尼菲篮状菌感染确诊组(血或组织液培育养出马尔尼菲篮状菌),简称A组(62例),及马尔尼菲篮状菌感染临床诊断组[根据临床症状、体征、血常规及(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞多指标诊断],简称B组(58例)。检测患者(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞的表达水平,采用受试者工作特征(receiver-operating characteristic,ROC)曲线下面积(area under the curve,AUC)评估上述指标联合检测对艾滋病患者感染马尔尼菲篮状菌的诊断效能。结果A组的(1-3)-β-D葡聚糖和PCT水平均高于B组,CD4^(+)T淋巴细胞个数低于B组(P<0.05);(1-3)-β-D葡聚糖、PCT、CD4^(+)T淋巴细胞联合检测的AUC为0.933,(1-3)-β-D葡聚糖单独检测的AUC是0.812,PCT单独检测的AUC为0.883,CD4^(+)T淋巴细胞单独检测的AUC是0.810,(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的AUC皆优于三项单独检测,表明(1-3)-β-D葡聚糖、PCT和CD4^(+)T淋巴细胞联合检测的诊断价值皆优于单一指标诊断,且联合检测的特异度、约登指数分别为92.43%和0.580,均高于三项单独检测。结论(1-3)-β-D葡聚糖联合PCT和CD4^(+)T淋巴细胞多指标对艾滋病马尔尼菲篮状菌感染具有非常高的临床诊断价值,能够帮助医生分析出高危风险患者,及时制定治疗方案,同时也承担预后效果的判断依据,对治疗艾滋病马尔尼菲篮状菌感染具有非常重要的研究价值。 展开更多
关键词 (1-3)-β-d葡聚糖 PCT CD4^(+)T淋巴细胞 艾滋病 马尔尼菲篮状菌感染
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Quasi-static and dynamic tensile behaviors in electron beam welded Ti-6Al-4V alloy
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作者 张静 谭成文 +2 位作者 任宇 王富耻 才鸿年 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2011年第1期39-44,共6页
The quasi-static and dynamic tensile behaviors in electron beam welded(EBW) Ti-6Al-4V alloy were investigated at strain rates of 10-3 and 103 s-1,respectively,by materials test system(MTS) and reconstructive Hopki... The quasi-static and dynamic tensile behaviors in electron beam welded(EBW) Ti-6Al-4V alloy were investigated at strain rates of 10-3 and 103 s-1,respectively,by materials test system(MTS) and reconstructive Hopkinson bars apparatus.The microstructures of the base metal(BM) and the welded metal(WM) were observed with optical microscope.The fracture characteristics of the BM and WM were characterized with scanning electronic microscope.In Ti-6Al-4V alloy joint,the flow stress of WM is higher than that of BM,while the fracture strain of WM is less than that of BM at strain rates of 103 and 10-3 s-1,respectively.The fracture strain of WM has apparent improvement when the strain rate rises from 10-3 to 103 s-1,while the fracture strain of BM almost has no change.At the same time,the fracture mode of WM alters from brittle to ductile fracture,which causes improvement of the fracture strain of WM. 展开更多
关键词 Ti-6Al-4V alloy electron beam welding quasi-static tensile behavior dynamic behavior fracture mode
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Molecular Dynamic Simulation of Melting Points of Trans-1,4,5,8- tetranitro-1,4,5,8-tetraazadacalin (TNAD) with Some Propellants
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作者 李小红 居学海 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2014年第4期412-418,J0001,共8页
Molecular dynamic simulation was employed to predict the melting points Tm of TNAD/HMX, TNAD/RDX, TNAD/DINA, and TNAD/DNP systems (tans-1,4,5,8- tetranitro-1,4,5,8-tetraazadacalin (TNAD), dinitropiperazine (DNP),... Molecular dynamic simulation was employed to predict the melting points Tm of TNAD/HMX, TNAD/RDX, TNAD/DINA, and TNAD/DNP systems (tans-1,4,5,8- tetranitro-1,4,5,8-tetraazadacalin (TNAD), dinitropiperazine (DNP), cyclotetramethylenetetranitroamine (HMX), cyclotrimethylenetrinitramine (RDX), and N-nitrodihydroxyethylaminedinitrate (DINA)). Tm was determined from the inflexion point on the curve of mean specific volume vs. temperature. The result shows that the Tm values of TNAD/HMX, TNAD/RDX, and TNAD/DINA systems are 500, 536, and 488 K, respectively. The TNAD/DNP system has no obvious Tm value, which shows the system is insoluble. Using Tm, the solubility of the four systems was analyzed. The radial distribution functions of the four systems were analyzed and the main intermolecular forces between TNAD and other energetic components are short-range interactions. The better the solubility is, the stronger the intermoleenlar interaction is. In addition, the force field energy at different temperature was also analyzed to predict Tm of the four systems. 展开更多
关键词 Melting point Molecular dynamic simulation Radial distribution function Force field energy Trans-1 4 5 8-tetranitro-1 4 5 8-tetraazadaealin (TNAD)
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Constitutive modeling for dynamic recrystallization kinetics of Mg-4Zn-2Al-2Sn alloy 被引量:3
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作者 赵东清 杨院生 +2 位作者 周吉学 刘玉 唐守秋 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2018年第2期340-347,共8页
In order to have a better understanding of the hot deformation behavior of the as-solution-treated Mg-4 Zn-2 Sn-2 Al(ZAT422) alloy, a series of compression experiments with a height reduction of 60% were performed i... In order to have a better understanding of the hot deformation behavior of the as-solution-treated Mg-4 Zn-2 Sn-2 Al(ZAT422) alloy, a series of compression experiments with a height reduction of 60% were performed in the temperature range of 498-648 K and the strain rate range of 0.01-5 s~(-1) on a Gleeble 3800 thermo-mechanical simulator. Based on the regression analysis by Arrhenius type equation and Avrami type equation of flow behavior, the activation energy of deformation of ZAT422 alloy was determined as 155.652 k J/mol, and the constitutive equations for flow behavior and the dynamic recrystallization(DRX) kinetic model of ZAT422 alloy were established. Microstructure observation shows that when the temperature is as low as 498 K, the DRX is not completed as the true strain reaches 0.9163. However, with the temperature increasing to 648 K, the lower strain rate is more likely to result in some grains' abnormal growth. 展开更多
关键词 Mg-4Zn-2Al-2Sn alloy hot deformation flow stress dynamic recrystallization
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Dynamic Downscaling of Summer Precipitation Prediction over China in 1998 Using WRF and CCSM4 被引量:16
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作者 MA Jiehua WANG Huijun FAN Ke 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2015年第5期577-584,共8页
To study the prediction of the anomalous precipitation and general circulation for the summer(June–July–August) of1998, the Community Climate System Model Version 4.0(CCSM4.0) integrations were used to drive ver... To study the prediction of the anomalous precipitation and general circulation for the summer(June–July–August) of1998, the Community Climate System Model Version 4.0(CCSM4.0) integrations were used to drive version 3.2 of the Weather Research and Forecasting(WRF3.2) regional climate model to produce hindcasts at 60 km resolution. The results showed that the WRF model produced improved summer precipitation simulations. The systematic errors in the east of the Tibetan Plateau were removed, while in North China and Northeast China the systematic errors still existed. The improvements in summer precipitation interannual increment prediction also had regional characteristics. There was a marked improvement over the south of the Yangtze River basin and South China, but no obvious improvement over North China and Northeast China. Further analysis showed that the improvement was present not only for the seasonal mean precipitation, but also on a sub-seasonal timescale. The two occurrences of the Mei-yu rainfall agreed better with the observations in the WRF model,but were not resolved in CCSM. These improvements resulted from both the higher resolution and better topography of the WRF model. 展开更多
关键词 seasonal climate prediction dynamic downscaling summer precipitation CCSM4 WRF
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Discrete Element with Flexible Connector for Dynamic Analysis of 3-D Beam Structures 被引量:2
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作者 Cheng, BR Zheng, ZC Hou, ZC 《China Ocean Engineering》 SCIE EI 1997年第1期11-20,共10页
Combined multi-body dynamics with structural dynamics, a new discrete element with flexible connector, which is applicable for 3-D beam structures, is developed in this paper. Both the generalized elastic coefficient ... Combined multi-body dynamics with structural dynamics, a new discrete element with flexible connector, which is applicable for 3-D beam structures, is developed in this paper. Both the generalized elastic coefficient matrix of the flexible connector and the mass matrix of discrete element may be off-diagonal in a general case. The zero-length rigid element is introduced to simulate the node at which multiple elements are jointed together. It may also be effective when the axes of adjacent elements are not in the same line. The examples for eigenvalue calculation show that the model is successful. It can be extended to the geometric nonlinear response analysis. 展开更多
关键词 discrete element flexible connector zero-length rigid element 3-d beam structures dynamic analysis
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Dynamic recrystallization during hot torsion of Al-4Mg alloy 被引量:6
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作者 Junpin Lin, Yanli Wang, Zhi Lin, and Guoliang ChenState Key Laboratory of Advanced Metal Materials, University of Science and Technology Beijing, Beijing 100083, China 《Journal of University of Science and Technology Beijing》 CSCD 2003年第2期45-48,共4页
Binary Al-4Mg alloy have been deformed by hot torsion at 300-500 deg C andstrain rates of 0.006-1.587 s^(-1) to a true strain of 5.5. The specimens were annealed in vacuumfor 1.5 h at 500 deg C and then water quenched... Binary Al-4Mg alloy have been deformed by hot torsion at 300-500 deg C andstrain rates of 0.006-1.587 s^(-1) to a true strain of 5.5. The specimens were annealed in vacuumfor 1.5 h at 500 deg C and then water quenched. The study indicates that the dynamicrecrystallization occurs during hot torsion of Al-4Mg alloy in a certain range of Z parameter(Zener-Hollmon Parameter), i.e. 19.3 <= lnZ <=24.8. Increasing the strain rate at higher deformationtemperature or reducing the strain rate at lower deformation temperature accelerates the occurrenceof dynamic recrystallization in the alloy. 展开更多
关键词 Al-4Mg alloy dynamic recrystallization hot torsion
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3-D fracture network dynamic simulation based on error analysis in rock mass of dam foundation 被引量:4
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作者 ZHONG Deng-hua WU Han +2 位作者 WU Bin-ping ZHANG Yi-chi YUE Pan 《Journal of Central South University》 SCIE EI CAS CSCD 2018年第4期919-935,共17页
Accurate 3-D fracture network model for rock mass in dam foundation is of vital importance for stability,grouting and seepage analysis of dam foundation.With the aim of reducing deviation between fracture network mode... Accurate 3-D fracture network model for rock mass in dam foundation is of vital importance for stability,grouting and seepage analysis of dam foundation.With the aim of reducing deviation between fracture network model and measured data,a 3-D fracture network dynamic modeling method based on error analysis was proposed.Firstly,errors of four fracture volume density estimation methods(proposed by ODA,KULATILAKE,MAULDON,and SONG)and that of four fracture size estimation methods(proposed by EINSTEIN,SONG and TONON)were respectively compared,and the optimal methods were determined.Additionally,error index representing the deviation between fracture network model and measured data was established with integrated use of fractal dimension and relative absolute error(RAE).On this basis,the downhill simplex method was used to build the dynamic modeling method,which takes the minimum of error index as objective function and dynamically adjusts the fracture density and size parameters to correct the error index.Finally,the 3-D fracture network model could be obtained which meets the requirements.The proposed method was applied for 3-D fractures simulation in Miao Wei hydropower project in China for feasibility verification and the error index reduced from 2.618 to 0.337. 展开更多
关键词 rock mass of dam foundation 3-d fracture network dynamic simulation fractal dimension error analysis relative absolute error(RAE) downhill simplex method
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Dynamics and Stability of Blind Grasping of a 3-Dimensional Object under Non-holonomic Constraints 被引量:1
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作者 Suguru Arimoto Morio Yoshida Ji-Hun Bae 《International Journal of Automation and computing》 EI 2006年第3期263-270,共8页
A mathematical model expressing the motion of a pair of multi-DOF robot fingers with hemi-spherical ends, grasping a 3-D rigid object with parallel fiat surfaces, is derived, together with non-holonomic constraints. B... A mathematical model expressing the motion of a pair of multi-DOF robot fingers with hemi-spherical ends, grasping a 3-D rigid object with parallel fiat surfaces, is derived, together with non-holonomic constraints. By referring to the fact that humans grasp an object in the form of precision prehension, dynamically and stably by opposable forces, between the thumb and another finger (index or middle finger), a simple control signal constructed from finger-thumb opposition is proposed, and shown to realize stable grasping in a dynamic sense without using object information or external sensing (this is called "blind grasp" in this paper). The stability of grasping with force/torque balance under non-holonomic constraints is analyzed on the basis of a new concept named "stability on a manifold". Preliminary simulation results are shown to verify the validity of the theoretical results. 展开更多
关键词 dynamics of 3-d grasping blind-grasping non-holonomic constraints stable grasping precision prehension
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THE ANALYSIS OF DYNAMIC STRESS INTENSITY FACTOR FOR SEMI-CIRCULAR SURFACE CRACK USING TIME-DOMAIN BEM FORMULATION 被引量:1
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作者 ZHONG Ming(钟明) +1 位作者 ZHANG Yong-yuan(张永元) 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2001年第11期1344-1351,共8页
The time-domain BEM was developed to analyze the dynamic stress intensity factor ( DSIF) of 3-D elastodynamic crack problems. To simulate the stress singularity along the front of a crack, eight-node isoparametric sin... The time-domain BEM was developed to analyze the dynamic stress intensity factor ( DSIF) of 3-D elastodynamic crack problems. To simulate the stress singularity along the front of a crack, eight-node isoparametric singular elements were used, and the DSIF for a semi-circular surface crack was firstly calculated based on displacement equation using the time-domain BEM formulation. The new scheme to determine the time step was brought forward. By the dynamic analysis program of time-domain BEM compiled by its, several numerical examples are presented, which demonstrate the unconditional stability and high accuracy of time-domain BEM applied to 3-D elastodynamic crack problems. 展开更多
关键词 time-domain BEM 3-d elastodynamic crack problems dynamic stress intensity factor
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Move a Tropical Cyclone with 4D-Var and Vortex Dynamical Initialization in WRF Model 被引量:2
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作者 WANG Ting PENG Yue-hua +2 位作者 ZHANG Bang-lin LEUNG Jeremy Cheuk-Hin SHI Wei-lai 《Journal of Tropical Meteorology》 SCIE 2021年第3期191-200,共10页
Previous studies showed that 4 D-Var technique used for data assimilation could be modified for weather control. This study demonstrates the ability of 4 D-Var to influence the future path of a tropical cyclone by cal... Previous studies showed that 4 D-Var technique used for data assimilation could be modified for weather control. This study demonstrates the ability of 4 D-Var to influence the future path of a tropical cyclone by calculating perturbations in WRF simulation. Given the background error covariance matrix, the initial field is improved by the vortex dynamic initialization technique. Our results show that 4 D-Var can be applied to control the trajectory of simulated tropical cyclones by producing "optimal" perturbations. In the numerical simulation experiment of Typhoon Mitag in 2019, after this kind of weather control similar to data assimilation, the tropical cyclone moved obviously,and the damaging wind over the coastline weakened. The prediction results after the initial field modified by 4 D-Var have a great change, and the position of the tropical cyclone moved about 0.5° southeastward after assimilation,which misses the southeast coast of China. Moreover, the damaging wind is also weakened. Since the 4 D-Var is premised on the assumption that the model is perfect and does not consider the model error, then the research plan to consider model error and introduce new methods is discussed in the paper. 展开更多
关键词 4D-VAR weather control Typhoon Mitag WRF model vortex dynamical initialization
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Molecular dynamics simulation of the material removal in the scratching of 4H-SiC and 6H-SiC substrates 被引量:5
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作者 Zige Tian Xun Chen Xipeng Xu 《International Journal of Extreme Manufacturing》 EI 2020年第4期86-100,共15页
Single crystal silicon carbide(SiC)is widely used for optoelectronics applications.Due to the anisotropic characteristics of single crystal materials,the C face and Si face of single crystal SiC have different physica... Single crystal silicon carbide(SiC)is widely used for optoelectronics applications.Due to the anisotropic characteristics of single crystal materials,the C face and Si face of single crystal SiC have different physical properties,which may fit for particular application purposes.This paper presents an investigation of the material removal and associated subsurface defects in a set of scratching tests on the C face and Si face of 4H-SiC and 6H-SiC materials using molecular dynamics simulations.The investigation reveals that the sample material deformation consists of plastic,amorphous transformations and dislocation slips that may be prone to brittle split.The results showed that the material removal at the C face is more effective with less amorphous deformation than that at the Si face.Such a phenomenon in scratching relates to the dislocations on the basal plane(0001)of the SiC crystal.Subsurface defects were reduced by applying scratching cut depths equal to integer multiples of a half molecular lattice thickness,which formed a foundation for selecting machining control parameters for the best surface quality. 展开更多
关键词 material removal mechanism molecular dynamics simulation subsurface defects SCRATCHING 4H-SiC and 6H-SiC
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Dynamic Expression of Hyperpolarization-activated Cyclic Nucleotide-gated Cation Channel 4 Involved in Microwave Induced Pacemaker Cell Injuries 被引量:3
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作者 LIU Yan Qing ZHAO Li +6 位作者 GAO Ya Bing DONG Ji WANG Hui YAO Bin Wei ZHOU Hong Mei WANG Shui Ming PENG Rui Yun 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2015年第11期823-828,共6页
To investigate the mechanisms of microwave induced pacemaker cell injuries, Wistar rats and the primary pacemaker cells of newborn Wistar rats were exposed to microwave at average power density of 50 mW/cm2. Slower sp... To investigate the mechanisms of microwave induced pacemaker cell injuries, Wistar rats and the primary pacemaker cells of newborn Wistar rats were exposed to microwave at average power density of 50 mW/cm2. Slower spontaneous beating rate, intercellular Ca2+ aggregation and cell membrane perforation were detected immediately after the exposure. Moreover, hyperpolarizationactivated cyclic nucleotide-gated cation channel 4 (HCN4) was down-regulated immediately after the exposure and up-regulated at 12 h after the exposure. In the sinoatrial node (SAN) of the rats, 展开更多
关键词 HCN In node dynamic Expression of Hyperpolarization-activated Cyclic Nucleotide-gated Cation Channel 4 Involved in Microwave Induced Pacemaker Cell Injuries SAN ISH Figure ACH AR
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MODELING OF DYNAMIC RECRYSTALLIZATION OF Ti6A14V ALLOY USING A CELLULAR AUTOMATON APPROACH 被引量:1
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作者 J.W. Zhao H. Ding +3 位作者 W.J. Zhao F.R. Cao H.L. Hou Z.Q. Li 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2008年第4期260-268,共9页
A cellular automaton (CA) model is established to simulate dynamic recrystallization (DRX) in the β single-phase field of Ti6Al4 V alloy, and the kinetics during DRX processing has been analyzed. The model employ... A cellular automaton (CA) model is established to simulate dynamic recrystallization (DRX) in the β single-phase field of Ti6Al4 V alloy, and the kinetics during DRX processing has been analyzed. The model employed considers the influences of dynamic recovery, nucleation rate, strain rate and dislocation density on DRX, and practical deformation parameters, such as temperature, strain and strain rate on DRX have been considered in the simulation. The simulated DRX grain size and DRX grain shape agree well with the experimental results, which shows the availability and lea- sibility of the cellular automaton method for the simulation of DRX. The result of kinetics analysis of DRX reveals that the Avrami exponent is variable ranging from 2.4 to 2.9, which increases with the increase of strain rate. 展开更多
关键词 Ti6A4 V alloyi dynamic recrystallization KINETICS MODELING Cellular automaton
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Microstructure Evolution and Dynamic Mechanical Properties of Laser Additive Manufacturing Ti-6Al-4V Under High Strain Rate 被引量:1
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作者 Tao Wang Lei Zhu +7 位作者 Changhong Wang Mingming Liu Ning Wang Lingchao Qin Hao Wang Jianbo Lei Jie Tang Jun Wu 《Journal of Beijing Institute of Technology》 EI CAS 2020年第4期568-580,共13页
The dynamic mechanical properties of the Ti-6Al-4V(TC4)alloy prepared by laser additive manufacturing(LAM-TC4)under the high strain rate(HSR)are proposed.The dynamic compression experiments of LAM-TC4 are conducted wi... The dynamic mechanical properties of the Ti-6Al-4V(TC4)alloy prepared by laser additive manufacturing(LAM-TC4)under the high strain rate(HSR)are proposed.The dynamic compression experiments of LAM-TC4 are conducted with the split Hopkinson pressure bar(SHPB)equipment.The results show that as the strain rate increases,the widths of the adiabatic shear band(ASB),the micro-hardness,the degree of grain refinement near the ASB,and the dislocation density of grains grow gradually.Moreover,the increase of dislocation density of grains is the root factor in enhancing the yield strength of LAM-TC4.Meanwhile,the heat produced from the distortion and dislocations of grains promotes the heat softening effect favorable for the recrystallization of grains,resulting in the grain refinement of ASB.Furthermore,the contrastive analysis between LAM-TC4 and TC4 prepared by forging(F-TC4)indicates that under the HSR,the yield strength of LAM-TC4 is higher than that of F-TC4. 展开更多
关键词 laser additive manufacturing TI-6AL-4V dynamic mechanics properties MICROSTRUCTURE
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New 4-imino-4H-Chromeno[2,3-d]Pyrimidin-3(5H)-Amine: Synthesis, Cytotoxic Effects on Tumoral Cell Lines and in Silico ADMET Properties
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作者 Marwa Dhiabi Sirine Karoui +7 位作者 Mehdi Fakhfakh Souhir Abid Emmanuelle Limanton Rémy Le Guével Thierry Charlier Ludovic Paquin Jean-Pierre Bazureau Houcine Ammar 《International Journal of Organic Chemistry》 2024年第3期107-122,共16页
The synthesis of new 4-imino-4H-chromeno[2,3-d]pyrimidin-3(5H)-amine in four steps including one step under microwave dielectric heating is reported. The structural identity of the synthesized compounds was establishe... The synthesis of new 4-imino-4H-chromeno[2,3-d]pyrimidin-3(5H)-amine in four steps including one step under microwave dielectric heating is reported. The structural identity of the synthesized compounds was established according to their spectroscopic analysis, such as FT-IR, NMR and mass spectroscopy. These new compounds were tested for their antiproliferative activities on seven representative human tumoral cell lines (Huh7 D12, Caco2, MDA-MB231, MDA-MB468, HCT116, PC3 and MCF7) and also on fibroblasts. Among them, only the compounds 6c showed micromolar cytotoxic activity on tumor cell lines (1.8 50 50 > 25 μM). Finally, in silico ADMET studies ware performed to investigate the possibility of using of the identified compound 6c as potential anti-tumor compound. 展开更多
关键词 2-Amino-4H-Chromene 4H-Chromeno[2 3-d]Pyrimidin-3(5H)-Amine Microwave Irradiation Tumoral Cell Line in Silico ADMET
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Hot deformation behaviors and dynamic recrystallization mechanism of Ti-35421 alloy inβsingle field 被引量:1
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作者 Tong LU Zhen-hua DAN +3 位作者 Kai LI Dan-qing YI Lian ZHOU Hui CHANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2022年第9期2889-2907,共19页
Hot deformation behaviors and microstructure evolution of Ti-3Al-5Mo-4Cr-2Zr-1Fe(Ti-35421)alloy in theβsingle field are investigated by isothermal compression tests on a Gleeble-3500 simulator at temperatures of 820-... Hot deformation behaviors and microstructure evolution of Ti-3Al-5Mo-4Cr-2Zr-1Fe(Ti-35421)alloy in theβsingle field are investigated by isothermal compression tests on a Gleeble-3500 simulator at temperatures of 820-900°C and strain rates of 0.001-1 s^(-1).The research results show that discontinuous yield phenomenon and rheological softening are affected by the strain rates and deformation temperatures.The critical conditions for dynamic recrystallization and kinetic model of Ti-35421 alloy are determined,and the Arrhenius constitutive model is constructed.The rheological behaviors of Ti-35421 alloys aboveβphase transformation temperature are predicted by the constitutive model accurately.The EBSD analysis proves that the deformation softening is controlled by dynamic recovery and dynamic recrystallization.In addition,continuous dynamic recrystallization is determined during hot deformation,and the calculation model for recrystallization grain sizes is established.Good linear dependency between the experimental and simulated values of recrystallized grain sizes indicates that the present model can be used for the prediction of recrystallized grain size with high accuracy. 展开更多
关键词 Ti-3Al-5Mo-4Cr-2Zr-1Fe alloy microstructure evolution Arrhenius constitutive model deformation softening continuous dynamic recrystallization
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Nonlinear Dynamic Analysis of MPEG-4 Video Traffic
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作者 GE Fei CAO Yang WANG Yuan-ni 《Wuhan University Journal of Natural Sciences》 EI CAS 2005年第6期1019-1024,共6页
The main research motive is to analysis and to veiny the inherent nonlinear character of MPEG-4 video. The power spectral density estimation of the video trafiic describes its 1/f^β and periodic characteristics.The p... The main research motive is to analysis and to veiny the inherent nonlinear character of MPEG-4 video. The power spectral density estimation of the video trafiic describes its 1/f^β and periodic characteristics.The priraeipal compohems analysis of the reconstructed space dimension shows only several principal components can be the representation of all dimensions. The correlation dimension analysis proves its fractal characteristic. To accurately compute the largest Lyapunov exponent, the video traffic is divided into many parts.So the largest Lyapunov exponent spectrum is separately calculated using the small data sets method. The largest Lyapunov exponent spectrum shows there exists abundant nonlinear chaos in MPEG-4 video traffic. The conclusion can be made that MPEG-4 video traffic have complex nonlinear be havior and can be characterized by its power spectral density,principal components, correlation dimension and the largest Lyapunov exponent besides its common statistics. 展开更多
关键词 MPEG-4 video traffic behavior nonlinear dynamic analysis power spectral density principal components analysis correlation dimension largest Lyapunov exponent
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In-situ three-dimensional visualization of dynamic tension deformation in ferrite stainless steels
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作者 ZHANG Zhixia BI Hongyun LI Xin 《Baosteel Technical Research》 CAS 2013年第4期56-61,共6页
An improved three-dimensional (3-D) experimental visualization methodology is presented tor evaluating the fracture mechanisms of ferritic stainless steels by in-situ tensile testing with an environmental scanning e... An improved three-dimensional (3-D) experimental visualization methodology is presented tor evaluating the fracture mechanisms of ferritic stainless steels by in-situ tensile testing with an environmental scanning electron microscope (ESEM). The samples were machined with a radial notched shape and a sloped surface. Both planar surface deformation and sloping surface deformation-induced microvoids were observed during dynamic tension experiments, where a greater amount of information could be obtained from the sloping surface. The results showed that microvoids formed at the grain boundaries of highly elongated large grains. The microvoids nucleated in the severely deformed regions grew nearly parallel to the tensile axis, predominantly along the grain boundaries. The microvoids nucleated at the interface of particles and the matrix did not propagate due to the high plasticity of the matrix. The large microvoids propagated and showed a zigzag shape along the grain boundaries,seemingly a consequence of the fracture of the slip bands caused by dislocation pile-ups. The final failure took place due to the reduction of the load-beating area. 展开更多
关键词 three-dimensional (3-d visualization MICROVOIDS in-situ dynamic tensile testing ferritic stainless steels
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