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利用GC-MS和LC-MS分析2-MMC、3-MMC、4-MMC甲卡西酮类活性物质
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作者 包少魁 于交远 +3 位作者 李晓光 金东海 陈纯华 张强 《中国药物依赖性杂志》 CAS CSCD 2023年第4期262-265,共4页
目的探索同时分析鉴定2-甲基甲卡西酮(2-MMC)、3-甲基甲卡西酮(3-MMC)、4-甲基甲卡西酮(4-MMC)的可行性。方法采用常规分析条件,利用气相色谱质谱法(GC-MS)和液相色谱质谱法(LC-MS)分别对2-MMC、3-MMC、4-MMC同时进行分析。结果2-MMC、3... 目的探索同时分析鉴定2-甲基甲卡西酮(2-MMC)、3-甲基甲卡西酮(3-MMC)、4-甲基甲卡西酮(4-MMC)的可行性。方法采用常规分析条件,利用气相色谱质谱法(GC-MS)和液相色谱质谱法(LC-MS)分别对2-MMC、3-MMC、4-MMC同时进行分析。结果2-MMC、3-MMC、4-MMC三者不能通过液相色谱质谱法完全分离,而气相色谱质谱法可将三者完全分离。结论同时对2-MMC、3-MMC、4-MMC进行分析鉴定时,应优先选择气相色谱质谱法。 展开更多
关键词 甲卡西酮类 2-mmc 3-mmc 4-mmc 气相色谱质谱法 液相色谱质谱法
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荧光试剂柱前衍生高效液相色谱-荧光检测生物检材中的氟乙酸钠 被引量:7
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作者 谢珍茗 施文兵 +1 位作者 刘岚 邓芹英 《分析科学学报》 CAS CSCD 2007年第6期685-688,共4页
建立了以4-溴甲基7-甲氧基香豆素(BrMMC)为柱前荧光衍生试剂,反相高效液相色谱荧光检测(HPLC-FLD)生物检材中氟乙酸钠的分析方法。采用Hewlett Packard RP-18色谱柱,以甲醇-水(60/40,V/V)为流动相,流速1.0mL/min,柱温26... 建立了以4-溴甲基7-甲氧基香豆素(BrMMC)为柱前荧光衍生试剂,反相高效液相色谱荧光检测(HPLC-FLD)生物检材中氟乙酸钠的分析方法。采用Hewlett Packard RP-18色谱柱,以甲醇-水(60/40,V/V)为流动相,流速1.0mL/min,柱温26℃,荧光检测:λex=319nm,λem=390nm,进样量2μL。结果表明:该法在氟乙酸钠含量为0.1~20μg/mL范围内与其峰面积呈良好的线性关系,线性相关系数为0.9996,检出限(S/N=3)为5×10^-10mol/mL,相对标准偏差(RSD)小于4%。本法用于中毒死亡者的血液样品及其它检材的测定,效果良好。 展开更多
关键词 氟乙酸钠 4-溴甲基-7-甲氧基香豆素(BrMMC) 4-氟乙酸-7-甲氧基香豆素甲酯(MMC-MFA) 高效液相色谱荧光检测
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五加皮抑制镉及丝裂霉素C诱发生殖细胞遗传损伤研究
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作者 刘冰 庞慧民 陆培信 《中国公共卫生学报》 1999年第1期23-24,共2页
研究五加皮(CortexAcanthopanasiaRadicis)对镉(Cd)及丝裂霉素C(MMC)诱发雄性小鼠生殖细胞遗传损伤的防护效应。结果表明,五加皮本身无诱变损伤作用,而对Cd及MMC诱发的遗传损伤均有较强... 研究五加皮(CortexAcanthopanasiaRadicis)对镉(Cd)及丝裂霉素C(MMC)诱发雄性小鼠生殖细胞遗传损伤的防护效应。结果表明,五加皮本身无诱变损伤作用,而对Cd及MMC诱发的遗传损伤均有较强的拮抗作用。提示,五加皮对雄性生殖细胞具有保护作用,是环境中的镉等化学物质的拮抗物质。 展开更多
关键词 五加皮 硫酸镉 丝裂霉素C 精子畸形 抗诱变
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Mechanical and Machining Properties Analysis of Al6061-Cu-Reinforced SiC<sub>P</sub>Metal Matrix Composite
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作者 Serajul Haque Prem Kumar Bharti Akhtar Hussain Ansari 《Journal of Minerals and Materials Characterization and Engineering》 2014年第1期54-60,共7页
The metal matrix composite (MMC), despite of its high stiffness, strength, corrosion resistance, wear resistance, non-react with chemicals and so many other tailored qualities which are never obtained in alloy of meta... The metal matrix composite (MMC), despite of its high stiffness, strength, corrosion resistance, wear resistance, non-react with chemicals and so many other tailored qualities which are never obtained in alloy of metals, has limited utilization due to the high cost of fabrication. In this study, a modest attempt has been made to find out the process parameters at which best mechanical properties of Al6061, 4% Cu and reinforced 5% SiCP ceramic MMC can be obtained. The addition of 4% Cu in Al6061 is more or less comparable to the composition duralumin, which are widely used in aerospace applications. SiCP is hard and has linear thermal expansion at high temperature. With reinforcement of SiCP in Al6061-Cu alloy, it can be postulated that hardness of MMC retains at high temperature applications. An analysis of Variance (ANOVA) and linear regression was used for analysis of data with the help of SPSS (Version-17.0). Independent parameters are five levels of pouring rates (1.5 cm/s, 2.0 cm/s, 2.5 cm/s, 3.0 cm/s and 3.5 cm/s), and material type (Al6061 + 4% Cu alloy and Al6061 + 4% Cu, reinforced 5% SiCp MMC processed using stir casting technique) and dependent parameters are hardness and impact strength material removal rates of workpiece. It is found that at different pouring rates material hardness and impact strength of workpiece are highly significant but the material removal rate of workpiece is having no significance value. At pouring rate of 2.5 cm/s and 700℃ ± 5℃ pouring temperature, optimum values of hardness and impact strength are observed as compared to other values of pouring rates (1.5 cm/s, 2.0 cm/s, 3.0 cm/s and 3.5 cm/s). Material Removal rate for work pieces of Al6061 + 4% Cu alloy is less as compared to MMC. So it can be concluded that MMC has better machining ability compared to Al6061 + 4% Cu alloy. Material removal rate of Al6061 + 4% Cu, reinforced 5% SiCP MMC has maximum values at 1.5 cm/s pouring rate compared to 2.0 cm/s, 2.5 cm/s, 3.0 cm/s and 3.5 cm/s pouring rates. With reinforcement of 5% SiC trend of mechanical properties is same, but the hardness and impact strength of MMCs are increased by 25% and 20% respectively. Also it is observed from scanning electron microscopy (SEM) that at pouring rate 2.5 cm/s a better homogeneity can be obtained. 展开更多
关键词 MMC Al6061 + 4% CU Alloy SIC Particulate STIR Casting Technique MECHANICAL Properties Scanning
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