The 1-azido-2-chloro-4-nitrobenzene was prepared by nucleophilic substitution between 2-chloro-4-nitro-1-(trifluoromethylsulfinyl)benzene and sodium azide, and its structure was characterized by NMR spectrum and X-ray...The 1-azido-2-chloro-4-nitrobenzene was prepared by nucleophilic substitution between 2-chloro-4-nitro-1-(trifluoromethylsulfinyl)benzene and sodium azide, and its structure was characterized by NMR spectrum and X-ray single-crystal diffraction. It crystallizes in the monoclinic system, space group P21/n, Z = 8 and Mr = 198.57. A cultivation process of the single crystal of unstable aryl azide was provided. The group of trifluoromethyl sulfinyl was found for the first time to be a new excellent leaving group of aromatic nucleophilic substitution reactions.展开更多
The reactions of 3,4 dichloro nitrobenzene with phenolates were performed by means of microwave irradiation. In comparison with other methods, the present one has the advatage of good yield, short reaction time, and s...The reactions of 3,4 dichloro nitrobenzene with phenolates were performed by means of microwave irradiation. In comparison with other methods, the present one has the advatage of good yield, short reaction time, and simplicity in operation.展开更多
文摘The 1-azido-2-chloro-4-nitrobenzene was prepared by nucleophilic substitution between 2-chloro-4-nitro-1-(trifluoromethylsulfinyl)benzene and sodium azide, and its structure was characterized by NMR spectrum and X-ray single-crystal diffraction. It crystallizes in the monoclinic system, space group P21/n, Z = 8 and Mr = 198.57. A cultivation process of the single crystal of unstable aryl azide was provided. The group of trifluoromethyl sulfinyl was found for the first time to be a new excellent leaving group of aromatic nucleophilic substitution reactions.
文摘The reactions of 3,4 dichloro nitrobenzene with phenolates were performed by means of microwave irradiation. In comparison with other methods, the present one has the advatage of good yield, short reaction time, and simplicity in operation.