N- (2,4-Dinitrophenyl)-4-amino-n-butyl aldehyde 3 was obtained with high yield of 80% when N- (2,4-dinitrophenyl)-L-proline 1 reacted with SOCl2 at room temperature. However, the anticipated product N- (2,4-dinitroph...N- (2,4-Dinitrophenyl)-4-amino-n-butyl aldehyde 3 was obtained with high yield of 80% when N- (2,4-dinitrophenyl)-L-proline 1 reacted with SOCl2 at room temperature. However, the anticipated product N- (2,4-dinitrophenyl)-tetrahydropyrrolyl-2- (4-methylthiophenyl) ketone 2 did not be produced. The mechanism was discussed in this article.展开更多
Composition of bromine and nitric acid in concentrated sulfuric acid is effective for bromination of strongly deactivated aromatic compounds and for nitration and bromination of moderately deactivated compounds in one...Composition of bromine and nitric acid in concentrated sulfuric acid is effective for bromination of strongly deactivated aromatic compounds and for nitration and bromination of moderately deactivated compounds in one stage. The question why brominating agent is more reactive than nitrating agent in relation to strongly deactivated aromatic compounds and is less reactive in relation to moderate deactivated ones is discussed.展开更多
文摘N- (2,4-Dinitrophenyl)-4-amino-n-butyl aldehyde 3 was obtained with high yield of 80% when N- (2,4-dinitrophenyl)-L-proline 1 reacted with SOCl2 at room temperature. However, the anticipated product N- (2,4-dinitrophenyl)-tetrahydropyrrolyl-2- (4-methylthiophenyl) ketone 2 did not be produced. The mechanism was discussed in this article.
文摘Composition of bromine and nitric acid in concentrated sulfuric acid is effective for bromination of strongly deactivated aromatic compounds and for nitration and bromination of moderately deactivated compounds in one stage. The question why brominating agent is more reactive than nitrating agent in relation to strongly deactivated aromatic compounds and is less reactive in relation to moderate deactivated ones is discussed.
