Diagnosis and treatment of breast cancer have been improved during the last decade; however, breast cancer is still a leading cause of death among women in the whole world. Early detection and accurate diagnosis of th...Diagnosis and treatment of breast cancer have been improved during the last decade; however, breast cancer is still a leading cause of death among women in the whole world. Early detection and accurate diagnosis of this disease has been demonstrated an approach to long survival of the patients. As an attempt to develop a reliable diagnosing method for breast cancer, we integrated support vector machine (SVM), k-nearest neighbor and probabilistic neural network into a complex machine learning approach to detect malignant breast tumour through a set of indicators consisting of age and ten cellular features of fine-needle aspiration of breast which were ranked according to signal-to-noise ratio to identify determinants distinguishing benign breast tumours from malignant ones. The method turned out to significantly improve the diagnosis, with a sensitivity of 94.04%, a specificity of 97.37%, and an overall accuracy up to 96.24% when SVM was adopted with the sigmoid kernel function under 5-fold cross validation. The results suggest that SVM is a promising methodology to be further developed into a practical adjunct implement to help discerning benign and malignant breast tumours and thus reduce the incidence of misdiagnosis.展开更多
We herein presented a case of calculi secondary to a migrated acupuncture needle.A 74-year-old woman with a history of acupuncture therapy for lumbago was referred to our hospital for treatment of ureteral and renal p...We herein presented a case of calculi secondary to a migrated acupuncture needle.A 74-year-old woman with a history of acupuncture therapy for lumbago was referred to our hospital for treatment of ureteral and renal pelvic calculi.Abdominal multi-detector computed tomography scans showed ipsilateral hydronephrosis and two calculi secondary to a migrated acupuncture needle.First,a percutaneous nephrolithotomy was performed to extract two calculi and fine needle fragments from the pelvis.Subsequently,residual needle fragments and calculi in the ureter were then removed by flexible transurethral lithotripsy using a holmium laser.In the present case,the formation of the calculi was caused by a migrated acupuncture needle.Calculi and needle fragments were removed safely endoscopically because the whole calculi and needle fragments were located in the ureteral lumen.ª2021 Editorial Office of Asian Journal of Urology.Production and hosting by Elsevier B.V.This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/).展开更多
Under ultrasound guidance, a blunt suture needle was inserted around the Glissonian pedicle and then sutured. This technique significantly reduced the blood loss and facilitated the procedure of partial hepatectomy. W...Under ultrasound guidance, a blunt suture needle was inserted around the Glissonian pedicle and then sutured. This technique significantly reduced the blood loss and facilitated the procedure of partial hepatectomy. We applied this technique in 182 patients who needed partial hepatectomy. We concluded that this method is simple and easy to occlude the vascular inflow and outflow, and allows an accurate delineation of the anatomic zone and therefore, simplifies the procedure of partial hepatectomy.展开更多
To provide the anatomical data for percutaneous radiofrequency thermocoagulation through foramen rotundum approach via anterior border of coronoid process in the treatment of V2 trigeminal neuralgia.80 dried cadaveric...To provide the anatomical data for percutaneous radiofrequency thermocoagulation through foramen rotundum approach via anterior border of coronoid process in the treatment of V2 trigeminal neuralgia.80 dried cadaveric adult skulls(160 sides)were examined.The depth of the first arrival with the needle from the lower margin of the zygomatic arch to the maxillary surface(L1),the depth(L2)that the needle reached the maxillary margin of pterygomaxillary fissure,and gliding distance(L3),the fissure width that the needle reached the maxillary margin of pterygomaxillary fissure(L4),the maximum length(LA)and width(LB)of the skull were measured.On the left side,the reference ranges of L1,L2,L3,L4 were(23.04±3.42)mm,(38.14±3.63)mm,(20.67土3.93)mm,(5.85土1.27)mm,respectively.And on the right side,these parameters were(22.96土3.34)mm,(38.40±3.49)mm,(20.82±3.93)mm,(5.86土1.33)mm,respectively.展开更多
目的验证改良经环甲膜肌电信号记录法用于全乳晕腔镜甲状腺手术术中神经监测安全性和可行性。方法行全乳晕腔镜单侧甲状腺手术病人50例。在使用气管插管表面电极的同时,一个双针电极经10 mm Trocar观察孔置入手术腔隙,在腔镜镜头引导下...目的验证改良经环甲膜肌电信号记录法用于全乳晕腔镜甲状腺手术术中神经监测安全性和可行性。方法行全乳晕腔镜单侧甲状腺手术病人50例。在使用气管插管表面电极的同时,一个双针电极经10 mm Trocar观察孔置入手术腔隙,在腔镜镜头引导下将针电极插入环甲肌直部和甲状软骨之间。在术中使用标准四步法(V1-R1-R2-V2)定位、显露并评估喉返神经功能。结果50例病人均成功实施了全乳晕腔镜单侧甲状腺手术。术中共监测了50条喉返神经,经环甲膜针电极和气管插管表面电极均成功记录到有效的肌电信号。经环甲膜针电极的肌电信号振幅大于气管插管表面电极[V1/R1=(2179.3±1252.3/2304.8±1644.0)μV vs(937.2±612.8/1088.9±613.5)μV]。术中未发生肌电信号丢失事件,肿瘤切除前后肌电信号无明显变化,手术前后电子喉镜均提示声带运动正常。结论改良经环甲膜肌电信号记录法用于全乳晕腔镜甲状腺手术中神经监测安全可行;安装方便,肌电信号强,不受气管插管位置影响,对腔镜手术操作影响小。展开更多
Currently,there is a strong focus on industrial production of chlorophyll as a natural pigment.Two factors are required in the economically feasible process to make chlorophyll production:material with high pigment co...Currently,there is a strong focus on industrial production of chlorophyll as a natural pigment.Two factors are required in the economically feasible process to make chlorophyll production:material with high pigment content and efficient extraction mechanism.In this work,extraction of chlorophyll from harvested black locust(Robinia pseudoacacia)leaves,Scots pine(Pinus sylvestris)needles,field sow thistle(Sonchus arvensis)leaves,and green microalga(Chlorella sp.)was discussed.The highest pigment content was detected in Chlorella cells(4.46%)followed by black locust leaves(1.63%),sow thistle leaves(1.48%)and pine needles(0.38%).The chlorophyll extraction rate was the highest for black locust leaves(k=3.59 h^(-1)),sow thistle leaves(k=2.90 h^(-1))and Chlorella cells(k=2.80 h^(-1))with the use of methanol as a solvent.In investigated materials,needles showed higher resistance for chlorophyll extraction(k=0.93 h^(-1))when compared to leaves and microalgae.Values of extraction kinetic constant were much lower for all materials(0.22-1.12 h^(-1))in the case of using ethanol as a solvent.Black locust leaves and Chlorella cells were proved to be the most attractive materials for chlorophyll production.展开更多
基金Joint Research Project Between Chongqing University and National University of Singapore (No. ARF-151-000-014-112)the Basic Research & Applied Basic Research Program of Chongqing University (No.71341103)Natural Science Foundation of Chongqing S & T Committee(No. CSTC,2006BB5240)
文摘Diagnosis and treatment of breast cancer have been improved during the last decade; however, breast cancer is still a leading cause of death among women in the whole world. Early detection and accurate diagnosis of this disease has been demonstrated an approach to long survival of the patients. As an attempt to develop a reliable diagnosing method for breast cancer, we integrated support vector machine (SVM), k-nearest neighbor and probabilistic neural network into a complex machine learning approach to detect malignant breast tumour through a set of indicators consisting of age and ten cellular features of fine-needle aspiration of breast which were ranked according to signal-to-noise ratio to identify determinants distinguishing benign breast tumours from malignant ones. The method turned out to significantly improve the diagnosis, with a sensitivity of 94.04%, a specificity of 97.37%, and an overall accuracy up to 96.24% when SVM was adopted with the sigmoid kernel function under 5-fold cross validation. The results suggest that SVM is a promising methodology to be further developed into a practical adjunct implement to help discerning benign and malignant breast tumours and thus reduce the incidence of misdiagnosis.
文摘We herein presented a case of calculi secondary to a migrated acupuncture needle.A 74-year-old woman with a history of acupuncture therapy for lumbago was referred to our hospital for treatment of ureteral and renal pelvic calculi.Abdominal multi-detector computed tomography scans showed ipsilateral hydronephrosis and two calculi secondary to a migrated acupuncture needle.First,a percutaneous nephrolithotomy was performed to extract two calculi and fine needle fragments from the pelvis.Subsequently,residual needle fragments and calculi in the ureter were then removed by flexible transurethral lithotripsy using a holmium laser.In the present case,the formation of the calculi was caused by a migrated acupuncture needle.Calculi and needle fragments were removed safely endoscopically because the whole calculi and needle fragments were located in the ureteral lumen.ª2021 Editorial Office of Asian Journal of Urology.Production and hosting by Elsevier B.V.This is an open access article under the CC BY-NC-ND license(http://creativecommons.org/licenses/by-nc-nd/4.0/).
基金supported by a grant from Scientific and Technological Project of Chongqing city(CSTC2012gg-yyjs10016)
文摘Under ultrasound guidance, a blunt suture needle was inserted around the Glissonian pedicle and then sutured. This technique significantly reduced the blood loss and facilitated the procedure of partial hepatectomy. We applied this technique in 182 patients who needed partial hepatectomy. We concluded that this method is simple and easy to occlude the vascular inflow and outflow, and allows an accurate delineation of the anatomic zone and therefore, simplifies the procedure of partial hepatectomy.
文摘To provide the anatomical data for percutaneous radiofrequency thermocoagulation through foramen rotundum approach via anterior border of coronoid process in the treatment of V2 trigeminal neuralgia.80 dried cadaveric adult skulls(160 sides)were examined.The depth of the first arrival with the needle from the lower margin of the zygomatic arch to the maxillary surface(L1),the depth(L2)that the needle reached the maxillary margin of pterygomaxillary fissure,and gliding distance(L3),the fissure width that the needle reached the maxillary margin of pterygomaxillary fissure(L4),the maximum length(LA)and width(LB)of the skull were measured.On the left side,the reference ranges of L1,L2,L3,L4 were(23.04±3.42)mm,(38.14±3.63)mm,(20.67土3.93)mm,(5.85土1.27)mm,respectively.And on the right side,these parameters were(22.96土3.34)mm,(38.40±3.49)mm,(20.82±3.93)mm,(5.86土1.33)mm,respectively.
文摘目的验证改良经环甲膜肌电信号记录法用于全乳晕腔镜甲状腺手术术中神经监测安全性和可行性。方法行全乳晕腔镜单侧甲状腺手术病人50例。在使用气管插管表面电极的同时,一个双针电极经10 mm Trocar观察孔置入手术腔隙,在腔镜镜头引导下将针电极插入环甲肌直部和甲状软骨之间。在术中使用标准四步法(V1-R1-R2-V2)定位、显露并评估喉返神经功能。结果50例病人均成功实施了全乳晕腔镜单侧甲状腺手术。术中共监测了50条喉返神经,经环甲膜针电极和气管插管表面电极均成功记录到有效的肌电信号。经环甲膜针电极的肌电信号振幅大于气管插管表面电极[V1/R1=(2179.3±1252.3/2304.8±1644.0)μV vs(937.2±612.8/1088.9±613.5)μV]。术中未发生肌电信号丢失事件,肿瘤切除前后肌电信号无明显变化,手术前后电子喉镜均提示声带运动正常。结论改良经环甲膜肌电信号记录法用于全乳晕腔镜甲状腺手术中神经监测安全可行;安装方便,肌电信号强,不受气管插管位置影响,对腔镜手术操作影响小。
文摘Currently,there is a strong focus on industrial production of chlorophyll as a natural pigment.Two factors are required in the economically feasible process to make chlorophyll production:material with high pigment content and efficient extraction mechanism.In this work,extraction of chlorophyll from harvested black locust(Robinia pseudoacacia)leaves,Scots pine(Pinus sylvestris)needles,field sow thistle(Sonchus arvensis)leaves,and green microalga(Chlorella sp.)was discussed.The highest pigment content was detected in Chlorella cells(4.46%)followed by black locust leaves(1.63%),sow thistle leaves(1.48%)and pine needles(0.38%).The chlorophyll extraction rate was the highest for black locust leaves(k=3.59 h^(-1)),sow thistle leaves(k=2.90 h^(-1))and Chlorella cells(k=2.80 h^(-1))with the use of methanol as a solvent.In investigated materials,needles showed higher resistance for chlorophyll extraction(k=0.93 h^(-1))when compared to leaves and microalgae.Values of extraction kinetic constant were much lower for all materials(0.22-1.12 h^(-1))in the case of using ethanol as a solvent.Black locust leaves and Chlorella cells were proved to be the most attractive materials for chlorophyll production.
基金supported by National Natural Science Foundation of China(10705049)Beijing Natural Science Foundation(1083011)Funding Project for Academic Human Resources Development in Institutions of Higher Learning[PHR(IHLB)]
