基于电容耦合式非接触电导检测(C4D)技术,设计研发了一种新型径向结构的非接触式电导测量传感器。该传感器利用串联谐振的原理,引入电感模块以消除耦合电容对测量的不利影响,扩大了测量范围,提高了测量灵敏度。同时,用仿真与实验相结合...基于电容耦合式非接触电导检测(C4D)技术,设计研发了一种新型径向结构的非接触式电导测量传感器。该传感器利用串联谐振的原理,引入电感模块以消除耦合电容对测量的不利影响,扩大了测量范围,提高了测量灵敏度。同时,用仿真与实验相结合的方法对传感器的电极张角进行了优化研究。在5.0、7.5、9.1、10.2和12.0 mm 5种不同内径的管道中进行了电导测量实验,电导测量相对误差均不超过5%,实验结果表明,所设计的新型非接触式径向C^4D电导测量传感器是可行和有效的。展开更多
The longitude tensile properties of 3-Dimension-4-directional（3D-4d） braided C/Si C composites（CMCs） were investigated with the help of a double scale model. This model involves micro-scale and unit-cell scale. In...The longitude tensile properties of 3-Dimension-4-directional（3D-4d） braided C/Si C composites（CMCs） were investigated with the help of a double scale model. This model involves micro-scale and unit-cell scale. In micro-scale, the tensile properties of fiber tows which involves matrix cracking, interfacial debonding, and fiber failure are studied. The unit-cell scale model can reflect the braided structure and simulate the tensile properties of 3D-4d CMCs by introducing the tensile properties of fiber tows into it. Quasi-static tensile tests of 3D-4d braided CMCs were performed on a PWS-100 test system. The predicted tensile stressstrain curve by the double scale model is in good agreement with that of the experimental results.展开更多
Double-scale model for three-dimension-4 directional（3D-4d） braided C/SiC composites has been proposed to investigate its elastic properties. The double-scale model involves micro-scale that takes fiber/ matrix/poro...Double-scale model for three-dimension-4 directional（3D-4d） braided C/SiC composites has been proposed to investigate its elastic properties. The double-scale model involves micro-scale that takes fiber/ matrix/porosity in fibers tows into consideration with unit cell which considers the 3D-4d braiding structure. Micro-optical photographs of composites have been taken to study the braided structure. Then a parameterized finite element model that reflects the structure of 3D-4d braided composites is proposed. Double-scale elastic modulus prediction model is developed to predict the elastic properties of 3D-4d braided C/SiC composites. Stiffness and eompliance-averaging method and energy method are adopted to predict the elastic properties of composites. Static-tension experiments have been conducted to investigate the elastic modulus of 3D-4d braided C/SiC composites. Finally, the effect of micro-porosity in fibers tows on the elastic modulus of 3D-4d braided C/SiC composites has been studied. According to the conclusion of this thesis, elastic modulus predicted by energy method and stiffness-averaging method both find good agreement with the experimental values, when taking the micro-porosity in fibers tows into consideration. Differences between the theoretical and experimental values become smaller.展开更多
A combined detection system involving simultaneous LIF and contacfless-conductometric measurements at the same place of the microfluidic chip was described. The LIF measurement was designed according to the confocal p...A combined detection system involving simultaneous LIF and contacfless-conductometric measurements at the same place of the microfluidic chip was described. The LIF measurement was designed according to the confocal principle and a moveable contactless-conduetivity detector was used in C^4D. Both measurements were mutually independent and advantageous in analyses of mixtures. Various experimental parameters affecting the response were examined and optimized. The performances were demonstrated by simultaneous detection of Rhodamine B. And the results showed that the combined detection system could be used sensitively and reliably.展开更多
通过考察电极长度及电极间距、检测管管径及材质、激励信号频率、电压和波形等参数对信噪比的影响,研制了一种适用于常规型离子色谱系统的电容耦合非接触式电导检测器(C^4D)。在抑制模式下,该检测器对常见无机阴离子(F^-、Cl^-、NO_2^-...通过考察电极长度及电极间距、检测管管径及材质、激励信号频率、电压和波形等参数对信噪比的影响,研制了一种适用于常规型离子色谱系统的电容耦合非接触式电导检测器(C^4D)。在抑制模式下,该检测器对常见无机阴离子(F^-、Cl^-、NO_2^-、Br^-、NO_3^-和SO_4^(2-))的检出限(信噪比=3)为0.02~0.08μmol/L;峰面积的相对标准偏差<1.8%(n=6);在0.1~10μm o l/L范围内上述6种无机阴离子线性关系良好,相关系数(R^2)>0.999。自制C4D的主要性能参数与商品化接触式电导检测器相当。该检测器具有结构简单、成本低廉、无电极污染等优点,有利于拓展离子色谱的应用范围。展开更多
The manner by which eukaryotic genomes are packaged into nuclei while maintaining crucial nuclear functions remains one of the fundamental mysteries in biology. Over the last ten years, we have witnessed rapid advance...The manner by which eukaryotic genomes are packaged into nuclei while maintaining crucial nuclear functions remains one of the fundamental mysteries in biology. Over the last ten years, we have witnessed rapid advances in both microscopic and nucleic acid-based approaches to map genome architecture, and the application of these approaches to the dissection of higher- order chromosomal structures has yielded much new information. It is becoming increasingly clear, for example, that interphase chromosomes form stable, multilevel hierarchical structures. Among them, self-associating domains like so-called topologically associating domains （TADs） appear to be building blocks for large-scale genomic organization. This review describes features of these broadly-defined hierarchical structures, insights into the mechanisms underlying their formation, our current understanding of how interactions in the nuclear space are linked to gene regulation, and important future directions for the field.展开更多
文摘基于电容耦合式非接触电导检测(C4D)技术,设计研发了一种新型径向结构的非接触式电导测量传感器。该传感器利用串联谐振的原理,引入电感模块以消除耦合电容对测量的不利影响,扩大了测量范围,提高了测量灵敏度。同时,用仿真与实验相结合的方法对传感器的电极张角进行了优化研究。在5.0、7.5、9.1、10.2和12.0 mm 5种不同内径的管道中进行了电导测量实验,电导测量相对误差均不超过5%,实验结果表明,所设计的新型非接触式径向C^4D电导测量传感器是可行和有效的。
基金Funded by the National Basic Research Program of Chinathe National Natural Science Foundation of China(51675266)+3 种基金the Aeronautical Science Foundation of China(2014ZB52024)the Fundamental Research Funds for the Central Universities(NJ20160038)the Jiangsu Innovation Program for Graduate Education(CXLX13_165)the Fundamental Research Funds for the Central Universities
文摘The longitude tensile properties of 3-Dimension-4-directional（3D-4d） braided C/Si C composites（CMCs） were investigated with the help of a double scale model. This model involves micro-scale and unit-cell scale. In micro-scale, the tensile properties of fiber tows which involves matrix cracking, interfacial debonding, and fiber failure are studied. The unit-cell scale model can reflect the braided structure and simulate the tensile properties of 3D-4d CMCs by introducing the tensile properties of fiber tows into it. Quasi-static tensile tests of 3D-4d braided CMCs were performed on a PWS-100 test system. The predicted tensile stressstrain curve by the double scale model is in good agreement with that of the experimental results.
基金Funded by the National Basic Research Program of China,National Natural Science Foundation of China(No.51075204)Funding of Jiangsu Innovation Program for Graduate Education(No.CXLX13_165)+2 种基金the Fundamental Research Funds for the Central Universities,Aeronautical Science Foundation of China(No.2012ZB52026)Research Fund for the Doctoral Program of Higher Education of China(No.20070287039)NUAA Research Funding(No.NZ2012106)
文摘Double-scale model for three-dimension-4 directional（3D-4d） braided C/SiC composites has been proposed to investigate its elastic properties. The double-scale model involves micro-scale that takes fiber/ matrix/porosity in fibers tows into consideration with unit cell which considers the 3D-4d braiding structure. Micro-optical photographs of composites have been taken to study the braided structure. Then a parameterized finite element model that reflects the structure of 3D-4d braided composites is proposed. Double-scale elastic modulus prediction model is developed to predict the elastic properties of 3D-4d braided C/SiC composites. Stiffness and eompliance-averaging method and energy method are adopted to predict the elastic properties of composites. Static-tension experiments have been conducted to investigate the elastic modulus of 3D-4d braided C/SiC composites. Finally, the effect of micro-porosity in fibers tows on the elastic modulus of 3D-4d braided C/SiC composites has been studied. According to the conclusion of this thesis, elastic modulus predicted by energy method and stiffness-averaging method both find good agreement with the experimental values, when taking the micro-porosity in fibers tows into consideration. Differences between the theoretical and experimental values become smaller.
文摘A combined detection system involving simultaneous LIF and contacfless-conductometric measurements at the same place of the microfluidic chip was described. The LIF measurement was designed according to the confocal principle and a moveable contactless-conduetivity detector was used in C^4D. Both measurements were mutually independent and advantageous in analyses of mixtures. Various experimental parameters affecting the response were examined and optimized. The performances were demonstrated by simultaneous detection of Rhodamine B. And the results showed that the combined detection system could be used sensitively and reliably.
基金the National Natural Science Foundation of China, Grant (60571009)the Science Research Program of Education Bureau of Hubei Province under Grant (Q20082904).
文摘通过考察电极长度及电极间距、检测管管径及材质、激励信号频率、电压和波形等参数对信噪比的影响,研制了一种适用于常规型离子色谱系统的电容耦合非接触式电导检测器(C^4D)。在抑制模式下,该检测器对常见无机阴离子(F^-、Cl^-、NO_2^-、Br^-、NO_3^-和SO_4^(2-))的检出限(信噪比=3)为0.02~0.08μmol/L;峰面积的相对标准偏差<1.8%(n=6);在0.1~10μm o l/L范围内上述6种无机阴离子线性关系良好,相关系数(R^2)>0.999。自制C4D的主要性能参数与商品化接触式电导检测器相当。该检测器具有结构简单、成本低廉、无电极污染等优点,有利于拓展离子色谱的应用范围。
基金supported by the UW-CNOF Mapping Technology Development(Grant No.1U54DK107979)from the National Institutes of Health,USA to JSthe UW Bridge Fund from the University of Washington,USA to ZD
文摘The manner by which eukaryotic genomes are packaged into nuclei while maintaining crucial nuclear functions remains one of the fundamental mysteries in biology. Over the last ten years, we have witnessed rapid advances in both microscopic and nucleic acid-based approaches to map genome architecture, and the application of these approaches to the dissection of higher- order chromosomal structures has yielded much new information. It is becoming increasingly clear, for example, that interphase chromosomes form stable, multilevel hierarchical structures. Among them, self-associating domains like so-called topologically associating domains （TADs） appear to be building blocks for large-scale genomic organization. This review describes features of these broadly-defined hierarchical structures, insights into the mechanisms underlying their formation, our current understanding of how interactions in the nuclear space are linked to gene regulation, and important future directions for the field.
