<i><span style="font-family:Verdana;">Lithraea</span></i><span style="font-family:;" "=""> <i><span style="font-family:Verdana;">m...<i><span style="font-family:Verdana;">Lithraea</span></i><span style="font-family:;" "=""> <i><span style="font-family:Verdana;">molleoides</span></i><span style="font-family:Verdana;"> (Anacardiaceae) is a tree that grows in South America including Southern Brazil, Southern, and Eastern Bolivia, Southern Paraguay, Northern, and Central Argentina. Infusions, decoctions, or tinctures from its aerial parts (leaves, buds, and young stems) are employed in ethnomedicine mainly against respiratory, and digestive inflammations and illnesses. Antibacterial, antiviral, antioxidant, anti-inflammatory, and antinociceptive activities, among others, have been reported for </span><i><span style="font-family:Verdana;">L.</span></i> <i><span style="font-family:Verdana;">molleoides</span></i><span style="font-family:Verdana;">. Many of its biological activities have been associated with the reported presence of 5-alkenyl resorcinols. Alkyl/alkenyl catechols and alkyl/alkenyl resorcinols are very common in members of the Anacardiaceae family and several activities have been attributed to them. This work describes the isolation and the structural elucidation of three new 5-alkenyl resorcinols isolated from </span><i><span style="font-family:Verdana;">Lithraea</span></i> <i><span style="font-family:Verdana;">molleoides</span></i><span style="font-family:Verdana;"> reported in nature for the first time.</span></span>展开更多
A new halogenated biindole and a new apo-carotenone have been isolated from the ethanolic extract of the green alga Chaetomorpha basiretorsa Sethcell. On the basis of chemical and spectroscopic methods including 2D NM...A new halogenated biindole and a new apo-carotenone have been isolated from the ethanolic extract of the green alga Chaetomorpha basiretorsa Sethcell. On the basis of chemical and spectroscopic methods including 2D NMR technique, their structures have been elucidated as 4,4′-dichloro-5,5′-dibromo-7,7′-dimethoxy-2,2′-bi-1H-indole and 1′S*,4′R*-8-(4′-hydroxy-2′,6′,6′- trimethylcyclohex-2-enyl)-6-methyloct-3E,5E,7E-trien-2-one, respectively.展开更多
Z)-5-(Trideca-4-enyl)resorcinol (1) and gibbilimbols AD (25) were synthesized in 47%60% yields over 6 steps from commercially available starting materials. The Wittig reaction of various alkyl phosphonium bromides wit...Z)-5-(Trideca-4-enyl)resorcinol (1) and gibbilimbols AD (25) were synthesized in 47%60% yields over 6 steps from commercially available starting materials. The Wittig reaction of various alkyl phosphonium bromides with appropriate aldehydes in the presence of potassium tert-butoxide (t-BuOK) in anhydrous THF solution at room temperature served as the key step, and the result showed that only (Z)-configuration olefins were formed by this procedure. The synthesis of the (Z)-5-(trideca-4-enyl)resorcinol (1) was reported for the first time.展开更多
文摘<i><span style="font-family:Verdana;">Lithraea</span></i><span style="font-family:;" "=""> <i><span style="font-family:Verdana;">molleoides</span></i><span style="font-family:Verdana;"> (Anacardiaceae) is a tree that grows in South America including Southern Brazil, Southern, and Eastern Bolivia, Southern Paraguay, Northern, and Central Argentina. Infusions, decoctions, or tinctures from its aerial parts (leaves, buds, and young stems) are employed in ethnomedicine mainly against respiratory, and digestive inflammations and illnesses. Antibacterial, antiviral, antioxidant, anti-inflammatory, and antinociceptive activities, among others, have been reported for </span><i><span style="font-family:Verdana;">L.</span></i> <i><span style="font-family:Verdana;">molleoides</span></i><span style="font-family:Verdana;">. Many of its biological activities have been associated with the reported presence of 5-alkenyl resorcinols. Alkyl/alkenyl catechols and alkyl/alkenyl resorcinols are very common in members of the Anacardiaceae family and several activities have been attributed to them. This work describes the isolation and the structural elucidation of three new 5-alkenyl resorcinols isolated from </span><i><span style="font-family:Verdana;">Lithraea</span></i> <i><span style="font-family:Verdana;">molleoides</span></i><span style="font-family:Verdana;"> reported in nature for the first time.</span></span>
基金supported by national 863 project(Grant No.2004AA625030,2001AA620503)NNSFC(Grant No.20432030)Key Innovative Project of the Academy(Grant No.KZCX3-SW-215).
文摘A new halogenated biindole and a new apo-carotenone have been isolated from the ethanolic extract of the green alga Chaetomorpha basiretorsa Sethcell. On the basis of chemical and spectroscopic methods including 2D NMR technique, their structures have been elucidated as 4,4′-dichloro-5,5′-dibromo-7,7′-dimethoxy-2,2′-bi-1H-indole and 1′S*,4′R*-8-(4′-hydroxy-2′,6′,6′- trimethylcyclohex-2-enyl)-6-methyloct-3E,5E,7E-trien-2-one, respectively.
基金Project supported by the National Natural Science Foundation of China (No. QT program 20021001) and the Natural Science Foundation of Gansu Province (No. ZS011-A25-003-Z).
文摘Z)-5-(Trideca-4-enyl)resorcinol (1) and gibbilimbols AD (25) were synthesized in 47%60% yields over 6 steps from commercially available starting materials. The Wittig reaction of various alkyl phosphonium bromides with appropriate aldehydes in the presence of potassium tert-butoxide (t-BuOK) in anhydrous THF solution at room temperature served as the key step, and the result showed that only (Z)-configuration olefins were formed by this procedure. The synthesis of the (Z)-5-(trideca-4-enyl)resorcinol (1) was reported for the first time.