The thermal decomposition of a new antitumor agent, 4-{5-[ 3,4-dimethyl-5-（3,4,5-trimethoxyphenyl）thiophen-2-yl ]-2-methoxyphenyl} morpholine was studied by Differential Scanning Calorimetry （DSC） and Thermogravim...The thermal decomposition of a new antitumor agent, 4-{5-[ 3,4-dimethyl-5-（3,4,5-trimethoxyphenyl）thiophen-2-yl ]-2-methoxyphenyl} morpholine was studied by Differential Scanning Calorimetry （DSC） and Thermogravimetry （TG） / Derivative Thermogravimetry （ DTG ） methods at a flow rate of nitrogen gas of 120 mL/min, The kinetic parameters were obtained from the analysis of the corresponding curves by Kissinger＇s method, Ozawa＇s method and the integral method, The results indicate that the apparent activation energy and pre-exponential constants of the decomposition reaction are 106.67 kJ/mol and 10^6.19s^-1, respectively.展开更多
The crystal structure of 1-(1-t-butyl-5-methyl-4-pyrazolylcarbonyl)-3,5-dimeth- yl-1H-yl-pyrazole ([C14H20N4O]2, Mr = 520.68) has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to tr...The crystal structure of 1-(1-t-butyl-5-methyl-4-pyrazolylcarbonyl)-3,5-dimeth- yl-1H-yl-pyrazole ([C14H20N4O]2, Mr = 520.68) has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to triclinic, space group P with a = 11.049(4), b = 11.313(4), c = 13.964(5) , ?= 69.085(6), b = 75.962(6), = 62.245(6), V = 1436.7(9) 3, Z = 2, Dc = 1.204 g/cm3, m = 0.079 mm-1, F(000) = 560, R = 0.0790 and wR = 0.1416 for 4729 unique reflections with 2635 observed ones (I > 2(I)). The results indicate that the pyrazole rings display aromaticity. The four pyrazole moieties are approximately coplanar in each case. The dihedral angles between planes 1 and 2, 3 and 4 are 40.99 and 10.77? respectively.展开更多
The title compound (C28H27NO5S3, Mr= 553. 69) was prepared bythe reaction of a-thiobenzoylthioformmorholine with diethyl acetylene dicarboxylate.The crystal is monoclinic, space group P21/n with a= 9. 160(3), b= 17. 7...The title compound (C28H27NO5S3, Mr= 553. 69) was prepared bythe reaction of a-thiobenzoylthioformmorholine with diethyl acetylene dicarboxylate.The crystal is monoclinic, space group P21/n with a= 9. 160(3), b= 17. 726(3), c=16. 602(3) A ; β= 100. 375(13)°; V=2651. 4(10) A3, Z=4, Dc= 1. 387 g/cm3, μ(MoKa) =0. 319 mm-1, F(000) =1160, R=0. 0428, wR(F2) =0. 0910 for 2438 observed reflections (I>2(I)). X-ray analysis reveals that interatomic distances for C(5)-C(6), C(13)-C(14) and C(21)-C(22) are 1. 331(4), 1. 351(4), 1. 344(4)A respectively, which show that they are normal C=C double bonds. All S-C bondlengths are similar to typical S-C single bonds (1. 75 - 1. 78 A ). The five-membered ring A (C(5) -C(6) -S(2)-C(13) -S(1) ) (Fig. 1) and six-membered ringB (C(14) -C(15) -C(20) -C(21)-C(22)-S(3) ) (Fig. 1) adopt the flat twist conformation. Furthermore, the morpholine ring adopts chair conformtion.展开更多
2,5-Bis｛4-[2-（4-diphenylaminophenylene）vinylene]phenylene｝-1,3,4-oxadiazole was designed and synthesized through Wittig-Horner reaction by embedding triphenylamino as the hole injection group and 1,3,4-oxadiazole ...2,5-Bis｛4-[2-（4-diphenylaminophenylene）vinylene]phenylene｝-1,3,4-oxadiazole was designed and synthesized through Wittig-Horner reaction by embedding triphenylamino as the hole injection group and 1,3,4-oxadiazole as the electron-transporting group into stilbene,which is one kind of blue luminescent materials,And its chemical structure was also been determined according to the spectra and element analysis.The analytic results showed that its UV-vis absorption λmax is 372nm and photo-luminescence λmax equals 473nm in THF solution.The synthetic compound λmax and light quantum yields are vigrously effected with the solvent polarity.展开更多
基金SUPPORTED BY THE NATIONAL YOUNG SCHOLAR AWARD OF NSFC( NO. 30125043 ).
文摘The thermal decomposition of a new antitumor agent, 4-{5-[ 3,4-dimethyl-5-（3,4,5-trimethoxyphenyl）thiophen-2-yl ]-2-methoxyphenyl} morpholine was studied by Differential Scanning Calorimetry （DSC） and Thermogravimetry （TG） / Derivative Thermogravimetry （ DTG ） methods at a flow rate of nitrogen gas of 120 mL/min, The kinetic parameters were obtained from the analysis of the corresponding curves by Kissinger＇s method, Ozawa＇s method and the integral method, The results indicate that the apparent activation energy and pre-exponential constants of the decomposition reaction are 106.67 kJ/mol and 10^6.19s^-1, respectively.
基金the Natural Science Foundation of Shandong Province (No. Y2003B01) and NNSFC (No. 20172031)
文摘The crystal structure of 1-(1-t-butyl-5-methyl-4-pyrazolylcarbonyl)-3,5-dimeth- yl-1H-yl-pyrazole ([C14H20N4O]2, Mr = 520.68) has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to triclinic, space group P with a = 11.049(4), b = 11.313(4), c = 13.964(5) , ?= 69.085(6), b = 75.962(6), = 62.245(6), V = 1436.7(9) 3, Z = 2, Dc = 1.204 g/cm3, m = 0.079 mm-1, F(000) = 560, R = 0.0790 and wR = 0.1416 for 4729 unique reflections with 2635 observed ones (I > 2(I)). The results indicate that the pyrazole rings display aromaticity. The four pyrazole moieties are approximately coplanar in each case. The dihedral angles between planes 1 and 2, 3 and 4 are 40.99 and 10.77? respectively.
文摘The title compound (C28H27NO5S3, Mr= 553. 69) was prepared bythe reaction of a-thiobenzoylthioformmorholine with diethyl acetylene dicarboxylate.The crystal is monoclinic, space group P21/n with a= 9. 160(3), b= 17. 726(3), c=16. 602(3) A ; β= 100. 375(13)°; V=2651. 4(10) A3, Z=4, Dc= 1. 387 g/cm3, μ(MoKa) =0. 319 mm-1, F(000) =1160, R=0. 0428, wR(F2) =0. 0910 for 2438 observed reflections (I>2(I)). X-ray analysis reveals that interatomic distances for C(5)-C(6), C(13)-C(14) and C(21)-C(22) are 1. 331(4), 1. 351(4), 1. 344(4)A respectively, which show that they are normal C=C double bonds. All S-C bondlengths are similar to typical S-C single bonds (1. 75 - 1. 78 A ). The five-membered ring A (C(5) -C(6) -S(2)-C(13) -S(1) ) (Fig. 1) and six-membered ringB (C(14) -C(15) -C(20) -C(21)-C(22)-S(3) ) (Fig. 1) adopt the flat twist conformation. Furthermore, the morpholine ring adopts chair conformtion.
文摘2,5-Bis｛4-[2-（4-diphenylaminophenylene）vinylene]phenylene｝-1,3,4-oxadiazole was designed and synthesized through Wittig-Horner reaction by embedding triphenylamino as the hole injection group and 1,3,4-oxadiazole as the electron-transporting group into stilbene,which is one kind of blue luminescent materials,And its chemical structure was also been determined according to the spectra and element analysis.The analytic results showed that its UV-vis absorption λmax is 372nm and photo-luminescence λmax equals 473nm in THF solution.The synthetic compound λmax and light quantum yields are vigrously effected with the solvent polarity.
