期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
Synthesis, Characterization, Spectroscopic Properties of 2-(4-Dimethylaminophenyl)-5-fluoro-6-(morpholin-4-yl)-1H-benzimidazole and its Interaction with Calf Thymus DNA
1
作者 LingTianTANG YiWANG XinQiLIU ShaoWenHU TaiWeiCHU XiangYunWANG 《Chinese Chemical Letters》 SCIE CAS CSCD 2005年第3期345-348,共4页
Dimethylaminophenyl)-5-fluoro-6-(morpholin-4-yl)-1H-benzimidazole(1) has been synthesized and characterized by H-NMR, MS and elemental analysis. UV-Vis spectra of the 1 aqueous solutions at different pH values reveal ... Dimethylaminophenyl)-5-fluoro-6-(morpholin-4-yl)-1H-benzimidazole(1) has been synthesized and characterized by H-NMR, MS and elemental analysis. UV-Vis spectra of the 1 aqueous solutions at different pH values reveal that compound 1 can combine three protons. Its three protonation constants are determined by spectrophotometry and calculated by non-linear least squares. The results of steady-state fluorescence measurements indicate that a special interaction occurs between compound 1 and calf thymus DNA, of which the binding constant, Kb, is (2.30 ± 0.10)×l04 L/mol. Compound 1 in the concentration range of 10-8 to 1.2×10-6 mol/L could be used for quantitative determination of DNA. 展开更多
关键词 2-(4-Dimethylaminophenyl)-5-fluoro-6-(morpholin-4-yl)-1H-benzimidazole calf thymus DNA.
下载PDF
A New Halogenated Biindole and A New Apo-carotenone from Green Alga Chaetomorpha basiretorsa Setchell 被引量:6
2
作者 DaYongSHI LiJunHAN +5 位作者 JieSUN ShuaiLI SuJuanWANG YongChunYANG XiaoFAN JianGongSHI 《Chinese Chemical Letters》 SCIE CAS CSCD 2005年第6期777-780,共4页
A new halogenated biindole and a new apo-carotenone have been isolated from the ethanolic extract of the green alga Chaetomorpha basiretorsa Sethcell. On the basis of chemical and spectroscopic methods including 2D NM... A new halogenated biindole and a new apo-carotenone have been isolated from the ethanolic extract of the green alga Chaetomorpha basiretorsa Sethcell. On the basis of chemical and spectroscopic methods including 2D NMR technique, their structures have been elucidated as 4,4′-dichloro-5,5′-dibromo-7,7′-dimethoxy-2,2′-bi-1H-indole and 1′S*,4′R*-8-(4′-hydroxy-2′,6′,6′- trimethylcyclohex-2-enyl)-6-methyloct-3E,5E,7E-trien-2-one, respectively. 展开更多
关键词 Green alga Chaetomorpha basiretorsa Sethcell 4 4′-dichloro-5 5′-dibromo-7 7′-di- methoxy-2 2′-bi-1h-indole 1′S* 4′R*-8-(4′-hydroxy-2′ 6 6′-trimethylcyclohex-2-enyl)-6-methyl- oct-3E 5E 7E-trien-2-one.
下载PDF
阳桃根中苯醌类化合物的分离鉴定与含量测定 被引量:6
3
作者 温庆伟 陈春霞 +2 位作者 梁杏梅 徐小惠 黄仁彬 《中国实验方剂学杂志》 CAS 北大核心 2014年第11期70-73,共4页
目的:研究阳桃根(ACLR)中苯醌类化学成分的类型及含量测定方法。方法:利用色谱分离法、核磁共振技术对阳桃根药材60%乙醇提取物中的环己烷萃取部位进行分离、鉴定,并应用HPLC法对药材中的苯醌类化学成分进行含量测定。结果:分离... 目的:研究阳桃根(ACLR)中苯醌类化学成分的类型及含量测定方法。方法:利用色谱分离法、核磁共振技术对阳桃根药材60%乙醇提取物中的环己烷萃取部位进行分离、鉴定,并应用HPLC法对药材中的苯醌类化学成分进行含量测定。结果:分离得到2个苯醌类化合物:2-methoxy-6-nonyl-cyclohexa.2,5-diene-1,4-dione(MNDD);2-dodecyl-6-methoxy-cyclohexa-2,5-diene-1,4-dione(DMDD);MNDD,DMDD分别在0.177~2.657斗g和0.094~1.416μg进样量与峰面积有良好的线性关系;平均加样回收率为98.96%(RSD1.59%),99.55%(RSD0.98%)。结论:首次从植物中分离得到2个苯醌类化合物;HPLC测定方法简便、快速、稳定、准确可靠、重复性好,可用于阳桃根药材中MNDD,DMDD的质量控制。 展开更多
关键词 阳桃根 苯醌类化合物 分离鉴定 2-methoxy-6-nonyl-cyclohexa-2 5-diene-1 4-dione(MNDD) 2-dodecyl-6-methoxy-cyclohexa-2 5-diene-1 4-dione(DMDD)
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部