TMC-328与TMP-6复配调控聚乳酸结晶与性能

为了克服聚乳酸成核能力差。专用单一成核剂(TMC-328)改性价格昂贵且效果有限的不足,采用TMC-328/TMP-6来协同调控聚L-乳酸(PLLA)的结晶与性能,利用差示扫描量热仪(DSC)、X射线粉末衍射仪(WAXD)、偏光显微镜(POM)和力学性能测试手段系统研究了复合成核剂对PLLA结晶行为、晶体形态和力学性能方面的影响。结果表明,复合成核剂TMC-328/TMP-6显著提高了聚乳酸的结晶温度和结晶速率,成核效果优于传统的单一TMC-328成核剂,且不影响PLLA的结构和晶型。另外,适量的复合成核剂可以提高PLLA的韧性,在TMC-328含量为0.6%,TMP-6的含量为0.4%时,PLLA/TMC-328/TMP-6共混材料的缺口冲击强度达到了最大值4.33 kJ/m^2,较PLLA/TMC-328共混物和纯PLLA分别约提高了10.9%和1.3倍。

急性胰腺炎合并肝损伤时IL-6、氧自由基变化及IL-2、川芎嗪干预的实验研究

目的 :探讨IL - 6、氧自由基在急性胰腺炎 (acutepancreatitis,AP)合并肝损伤中的作用 ,及重组人白介素 - 2 (IL -2 )、川芎嗪的治疗价值。 方法 :SD大鼠 112只 ,随机分为 14组 ,每组 8只。 5 %牛磺胆酸钠逆行胰胆管内注射诱发大鼠AP动物模型 ,检测血浆IL - 6、SOD、MDA、ALT、AST、LDH、LIP、AMY ,并观察肝、胰病理变化。 结果 :①AP组血浆AMY、LIP、ALT、AST、LDH明显升高 (P <0 0 5或 0 0 1) ,镜下可见胰腺水肿、炎细胞浸润、坏死 ,肝脏肝窦充血、细胞浊肿及坏死 ,且损伤程度随时限延长而加重 ;②AP各组血浆IL - 6明显升高 (P <0 0 1) ;③AP各组MDA明显升高 (P <0 0 1)、SOD明显降低 (P <0 0 1)。④IL- 2治疗组、川芎嗪治疗组及IL - 2、川芎嗪联合应用组与NS组比较血浆IL - 6、MDA水平明显下降 (P <0 0 5 ) ,SOD明显升高(P <0 0 5 ) ,胰、肝病理损害程度减轻 ,并且AMY、LIP、ALT、AST、LDH均明显降低 (P <0 0 5 ) ,平均存活时间明显延长 (P <0 0 5 ) ;联合应用组降低IL - 6、MDA水平和减轻胰腺坏死优于单药组。 结论 :①IL - 6、氧自由基在急性胰腺炎合并肝损伤中明显升高 ,起损伤作用 ,而SOD明显降低 ,其保护作用减弱。检测血浆IL - 6、MDA。

基于STM32F103C8T6单片机的多功能智能手表设计

文中设计了一种能够实时监测人体温度、统计运动步数的多功能智能手表。设计采用STM32F103C8T6单片机作为系统主控,将德州仪器设计生产的TMP100作为温度采集传感器,可对人体温度、运动步数等参数进行采集、分析和显示。当体温数据处于不正常范围时,智能手表会发出相应的提示警告。经测试,文中设计的手表可实现准确计时与人体温度的实时监控及每日步数的实时记录,方便用户根据获取的体温及运动数据对自身的健康状况做出处理。

TS-1分子筛/FeCl_3催化氧化TMP合成TMBQ

以正硅酸乙酯为硅源,钛酸四丁酯为钛源,采用溶胶-凝胶法制备了TS-1分子筛.实验中改进了陈化和干燥工序,缩短了TS-1分子筛的制备周期,降低了成本.通过气相色谱对反应体系的定量分析,考察了TS-1的制备条件以及合成反应条件对TS-1分子筛催化活性的影响.结果显示,当硅钛摩尔比nSi/nTi在3.80~19.01范围内变化时,TMP的转化率xTMP和TMBQ的选择性sTMBQ变化较小;随着合成反应温度的升高,xTMP逐渐增加直至TMP完全转化,但是sTMBQ随着温度的升高呈现先升高后降低的变化规律;增加合成反应时间,xTMP以及sTMBQ迅速增加,然后趋于稳定.在实验测试范围内,TMBQ的最大收率yTMBQ为87.87%.使用GC-MS对上述最佳反应条件下生成的产物进行分析,结果表明主产物为TMBQ.

Protective effect of TMP on pancreas function of acute pancreatitis rats

Objective:To explore the protective effect and mechanism of Tetramethyl Pyrazine(TMP)on the pancreas function of acute pancreatitis rats.Methods:A total of 75 SD rats were randomly divided into three groups(A,B,C) with 25 rats in each group.Group A served as sham operation group.In the groups B and C,AP model was prepared as by injecting taurocholic acid sodium.Group B was model group.After modeling,rats were administrated by intraperitoneal injection of normal saline.Group C was TMP treatment group,which was administrated by intraperitoneal injection of 0.6% TMP after modeling.The rat blood specimens in each group were collected with 1 mL/100 g solution after modeling of 2,6.12 and 24 h.Levels of amylase(AMS).blood urea nitrogen(BUN),creatinine(CR).TNF-α and IL-6 were detected,and 5 rats were sacrificed.Histopathological examination was performed in he pancreatic tissue specimens of each group to observe pancreatic tissue damage.Results:After modeling in each time point.AMS,BUN.CR.TNF-α and IL-6 in groups B and C were significantly higher than that of in group A(P<0.05).After modeling of 2 h.AMS.BUN and CR in group B increased significantly and reached the peak value at6 h.After modeling of 12 h.scrum level of TNF-α and IL-6 were significantly lower than that of in control group,while after 24 h of modeling,serum level of AMS.BUN,CR,TNF-α and IL-6 were significantly lower than that of in control group(P<0.05).The histological observation showed that pancreatic tissue in rats of group A was normal without damage lesions.Massive bleeding,necrosis and serious injury were visible in pancreatic tissue of group B.The rut pancreatic tissue was bleeding in group C with small pieces of necrotic lesions.The degree of inflammatory cell infiltration was lower than group B.and the degree of injury was significantly lower than group B.Conclusions:TMP can significantly decrease the serum level of TNF- α and IL-6 in AP rats,inhibits inflammatory response of AP.and has significant protective effect on pancreatic tissue and function in AP rats.

光照条件下冰相中激发三线态溶解性有机物的生成及其对三甲基苯酚的光敏化降解作用

选用两种天然有机物Upper Mississippi River NOM(UMRNOM)和Suwannee River NOM(SRNOM)作为光敏化剂,以500 W高压汞灯模拟太阳光照,用2,4,6-三甲基苯酚(TMP)作为探针,进行光解实验.考察了TMP是否可以作为冰相中激发三线态溶解性有机物(^(3)DOM^(*))的探针,以及溶解性有机碳(DOC)浓度、pH值和溶解氧含量对光反应生成^(3)DOM^(*)的影响.结果表明,TMP的直接光降解和单线态氧(1O2)、羟基自由基(•OH)对TMP检测^(3)DOM^(*)的影响可以忽略,TMP可以作为冰冻样品中^(3)DOM^(*)的探针.UMRNOM的荧光强度和光化学活性低于SRNOM,在光反应中^(3)DOM^(*)的生成量低.两种DOM的SUVA254、E2/E3和荧光指数均与pH没有相关性,产生的^(3)DOM^(*)也与pH不相关.^(3)DOM^(*)生成量随着DOC浓度的增加而增加,单位DOC的^(3)DOM^(*)生成量随着浓度的增加而减少.此外,充入氮气的样品中TMP的降解速率比空气饱和样品分别高13.15%和16.43%.

Sulfite activation by ZnO-encapsulated hydrogels for degradation of trimethylphenol

Trimethylphenol is an organic toxic byproduct of industrial process,which is difficult to be eliminated through conventional degradation without harsh conditions.In this work,a sulfite-based oxidation process activated by ZnO-embedded hydrogel was studied for the degradation of 2,4,6-trimethylphenols in the ambient conditions.The ZnO/Na_(2)SO_(3)oxidative system can effectively degrade trimethylphenol via the generation of radicals such as SO_(4)^(-)·,OH·,and SO_(3)^(−)·.The presence of hydrogel matrix facilitates the distribution and recyclability of ZnO catalysts while maintaining high degradation kinetics and little leaching of metal ions.Results suggest the promising potential of ZnO-hydrogel in wastewater treatment with good performance in terms of pH sensitivity,anion interference,recyclability,etc.The combination of ZnO catalysts,hydrogel,and sulfite-based advanced oxidation process may provide essential support for the current treatment of alkylated phenols with strong potential in the commercial scale-ups.