Objective: To validate a Greek version of the structured self-reported 8-item Morisky Medication Adherence Scale (MMAS-8) and determine its psychometric properties in patients with chronic illnesses. Methods: A cross-...Objective: To validate a Greek version of the structured self-reported 8-item Morisky Medication Adherence Scale (MMAS-8) and determine its psychometric properties in patients with chronic illnesses. Methods: A cross-sectional survey was conducted in a small public hospital and a public health care centre, in a rural town in western Greece. The sample consisted of 100 patients with various chronic illnesses. Data were collected between January-May 2011, on the Greek version of the MMAS-8 and Beliefs about Medicines Questionnaire (BMQ). Results: Scale’s reliability analysis revealed an overall Cronbach’s alpha of 0.753 and the corrected item to total correlations, were greater than 0.30 for each of the 8 items comprising the medication adherence scale, showing good internal consistency. Convergent validity was supported by a significant correlation between the present scale’s total score and the BMQ-Specific Necessity score (Spearman’s rho = 0.492, p < 0.001). Conclusion: The current study showed acceptable reliability and validity of the Greek version of the 8-item MMAS to measure adherence to medications for various chronic illnesses. The validated Greek version of the MMAS-8 can help towards understanding adherence barriers in Greece so as to develop effective strategies to increase adherence and reduce the costs.展开更多
目的探讨中国高血压患者用药依从性与不同年龄组、性别、测量工具、经济水平和文化程度之间的差异。方法使用3个英文数据库(PubMed,Web of Science和Embase)和3个中文数据库(知网、万方和维普)检索在2010年1月—2018年9月发表的相关文...目的探讨中国高血压患者用药依从性与不同年龄组、性别、测量工具、经济水平和文化程度之间的差异。方法使用3个英文数据库(PubMed,Web of Science和Embase)和3个中文数据库(知网、万方和维普)检索在2010年1月—2018年9月发表的相关文献。随机效应模型用于计算效应量大小和95%CI,另外进行了亚组分析,以确定这些比较中潜在的异质性来源。结果最终27篇文献被纳入本次研究,包括来自14个省、3个直辖市和1个特别行政区的20140名参与者。分析结果显示,我国的高血压患者用药依从率为42.0%(95%CI:36.0%~48.0%)。通过亚组分析,8项Morisky用药依从性量表作为测量工具的依从率为49.4%(95%CI:38.9%~59.9%);而4项Morisky用药依从量表为37.5%(95%CI:31.1%~44.0%)。具有小学或以下,中学,大专或以上学历的患者的用药依从率分别为49.5%,49.6%和53.6%。男性患者(47.5%)的药物依从率略低于女性(48.4%)。≥60岁的患者(51.0%)的用药依从率高于<60岁的患者(46.9%)。在发达地区的参与者的用药依从率(48.3%)比不发达地区(37.5%)更高。结论中国高血压患者用药依从率相对较低,不同的测量工具可能会影响患者的用药依从率,学历、性别、经济水平是高血压患者用药依从性的影响因素。目前急需有效的干预措施来解决和缓解这一问题。展开更多
文摘Objective: To validate a Greek version of the structured self-reported 8-item Morisky Medication Adherence Scale (MMAS-8) and determine its psychometric properties in patients with chronic illnesses. Methods: A cross-sectional survey was conducted in a small public hospital and a public health care centre, in a rural town in western Greece. The sample consisted of 100 patients with various chronic illnesses. Data were collected between January-May 2011, on the Greek version of the MMAS-8 and Beliefs about Medicines Questionnaire (BMQ). Results: Scale’s reliability analysis revealed an overall Cronbach’s alpha of 0.753 and the corrected item to total correlations, were greater than 0.30 for each of the 8 items comprising the medication adherence scale, showing good internal consistency. Convergent validity was supported by a significant correlation between the present scale’s total score and the BMQ-Specific Necessity score (Spearman’s rho = 0.492, p < 0.001). Conclusion: The current study showed acceptable reliability and validity of the Greek version of the 8-item MMAS to measure adherence to medications for various chronic illnesses. The validated Greek version of the MMAS-8 can help towards understanding adherence barriers in Greece so as to develop effective strategies to increase adherence and reduce the costs.
文摘目的探讨中国高血压患者用药依从性与不同年龄组、性别、测量工具、经济水平和文化程度之间的差异。方法使用3个英文数据库(PubMed,Web of Science和Embase)和3个中文数据库(知网、万方和维普)检索在2010年1月—2018年9月发表的相关文献。随机效应模型用于计算效应量大小和95%CI,另外进行了亚组分析,以确定这些比较中潜在的异质性来源。结果最终27篇文献被纳入本次研究,包括来自14个省、3个直辖市和1个特别行政区的20140名参与者。分析结果显示,我国的高血压患者用药依从率为42.0%(95%CI:36.0%~48.0%)。通过亚组分析,8项Morisky用药依从性量表作为测量工具的依从率为49.4%(95%CI:38.9%~59.9%);而4项Morisky用药依从量表为37.5%(95%CI:31.1%~44.0%)。具有小学或以下,中学,大专或以上学历的患者的用药依从率分别为49.5%,49.6%和53.6%。男性患者(47.5%)的药物依从率略低于女性(48.4%)。≥60岁的患者(51.0%)的用药依从率高于<60岁的患者(46.9%)。在发达地区的参与者的用药依从率(48.3%)比不发达地区(37.5%)更高。结论中国高血压患者用药依从率相对较低,不同的测量工具可能会影响患者的用药依从率,学历、性别、经济水平是高血压患者用药依从性的影响因素。目前急需有效的干预措施来解决和缓解这一问题。
