This paper investigated a rapid one pot synthesis method of some substituted（9 carbazoly） carboxylic acids（3a3m）. The reaction was carried out by mixing of the 9H carbazoles derivatives with bromo esters and potas...This paper investigated a rapid one pot synthesis method of some substituted（9 carbazoly） carboxylic acids（3a3m）. The reaction was carried out by mixing of the 9H carbazoles derivatives with bromo esters and potassium hydroxide using DMF as solvent under microwave irradiation without catalyst. The optimized experiment conditions were 48 min irradiation time and 375 W microwave power. The required range of molar ratio of KOH to substituted carbazole was 35. The biological activities of some compounds have been tested. They have medium to weak antimicrobial activities.展开更多
文摘This paper investigated a rapid one pot synthesis method of some substituted（9 carbazoly） carboxylic acids（3a3m）. The reaction was carried out by mixing of the 9H carbazoles derivatives with bromo esters and potassium hydroxide using DMF as solvent under microwave irradiation without catalyst. The optimized experiment conditions were 48 min irradiation time and 375 W microwave power. The required range of molar ratio of KOH to substituted carbazole was 35. The biological activities of some compounds have been tested. They have medium to weak antimicrobial activities.
