Identification of magnitude and orientation for spatially applied loading is highly desired in the fields of not only the machinery components but also human-machine interaction.Despite the fact that the 3-axis force ...Identification of magnitude and orientation for spatially applied loading is highly desired in the fields of not only the machinery components but also human-machine interaction.Despite the fact that the 3-axis force sensor with different structures has been proposed to measure the spatial force,there are still some common limitations including the multi-step manufacturing-assembly processes and complicated testing of decoupling calibration.Here,we propose a rapid fabrication strategy with low-cost to achieve high-precision 3-axis force sensors.The sensor is designed to compose of structural Maltese cross base and sensing units.It is directly fabricated within one step by a hybrid 3D printing technology combining deposition modeling(FDM)with direct-ink-writing(DIW).In particular,a machine learning(ML)model is used to convert the strain signal to the force components.Instead of a mount of calibration tests,this ML model is trained by sufficient simulation data based on programmed batch finite element modeling.This sensor is capable of continuously identifying a spatial force with varying magnitude and orientation,which successfully quantify the applied force of traditional Chinese medicine physiotherapy including Gua Sha and massage.This work provides insight for design and rapid fabrication of multi-axis force sensors,as well as potential applications.展开更多
A novel technique of immobilizing indicator dyes by electrostatic adsorption and covalent bonding to fabricate optical sensors was developed.3-Amino-9-ethylcarbazole(AEC)was attached to the outmost surface of quartz g...A novel technique of immobilizing indicator dyes by electrostatic adsorption and covalent bonding to fabricate optical sensors was developed.3-Amino-9-ethylcarbazole(AEC)was attached to the outmost surface of quartz glass slide via aminosilanizing the slide,crosslinking chitosan,adsorbing Au nanoparticle,self-assembling HS(CH2)11OH,and coupling AEC.Thus, an AEC-immobilized optical sensor was obtained.The sensor exhibits a wide linear response range from 7.0×10- 7to 1.0×10 -4 mol/L and a correlation coefficient of 0.995 9 for the detection of 2-nitrophenol.The detection limit and response time of the sensor are 1.0×10- 7mol/L and less than 10 s,respectively.The fluorescence intensity of the used sensor can be restored to the blank value by simply rinsing with blank buffer.A very effective matrix for immobilizing indicator dye is provided by the proposed technique, which is adaptable to other indicator dyes with amino groups besides AEC.展开更多
In this article, we used the self-excitation and self-inductance characteristics of polyvinylidene fluoride(PVDF) piezoelectric materials, combined with the powerful signal processing and calculation analysis capabili...In this article, we used the self-excitation and self-inductance characteristics of polyvinylidene fluoride(PVDF) piezoelectric materials, combined with the powerful signal processing and calculation analysis capabilities of integrated circuits, for the first time to explore a set of microcantilever sensor "readout system" without additional driver(self-driving) and can realize self-sensing external signal(self-sensing).It was successfully applied to the unlabeled detection of avian influenza virus(AIV) H9N_(2). The specific force of the antigen-antibody complexes on the surface of the microcantilever leads to the change of the stress of the cantilever, which drives the constructed detection device, and does not require an additional excitation source to drive it, that is, the self-driving part. At the same time, due to the movement of piezoelectric charges in the film caused by the positive piezoelectric effect of the PVDF film, self-inductive charges are generated on the surface of the sensor dielectric. The charge signal is converted into a voltage signal, and the sensing part is completed, that is, self-sensing. The immunosensor has a linear range of100-1000 ng/m L with a detection limit of 2.9 ng/m L. The method will also open up a new avenue for the detection of other analytes based on antigen-antibody responses.展开更多
A three-dimensional （3D） metal-organic framework （MOF） ZnL＇O.5H20＂O.75DMF （H2L=9-（pyridin-4-yl）-9H-carbazole- 3,6-dicarboxylic acid, DMF=N,N-dimethylformamide） has been synthesized under solvotherrnal condit...A three-dimensional （3D） metal-organic framework （MOF） ZnL＇O.5H20＂O.75DMF （H2L=9-（pyridin-4-yl）-9H-carbazole- 3,6-dicarboxylic acid, DMF=N,N-dimethylformamide） has been synthesized under solvotherrnal condition. Crystal structure analysis shows that, in ZnL, each dinuclear Zn2（COO）2 unit is doubly-bridged to the other two by the carbazole moieties to form the 1D chains, which are further connected together by pyridine moieties to lead to the 3D framework. ZnL exhibits both high structural stability and good luminescent stability in water with the pH range of 4-10. ZnL displays the luminescent quenching response for Fe3＋ in water with good linear correlation between the quenching efficiency and the concentration with Ksv of 10800 M 1 in the low concentration range of 0-0.1 mM. Interestingly, it is observed that the sensing performance for Fe3＋ is stable in the pH range of 4-9, enabling ZnL to detect Fe3＋ ions in weak acidic and weak basic solutions.展开更多
P-xylene(p-C_(8)H_(10))is extremely harmful and dangerous to human health due to high toxicity and strong carcinogenicity.Exploring sensitive material to effectively detect p-xylene is of importance.In this paper,pero...P-xylene(p-C_(8)H_(10))is extremely harmful and dangerous to human health due to high toxicity and strong carcinogenicity.Exploring sensitive material to effectively detect p-xylene is of importance.In this paper,perovskite single crystal(C_(4)H_(9)NH_(3))_(2)PbI_(4) has been successfully synthesized via solution method.The obtained product was analyzed by single crystal X-ray diffraction.With the space group Pbca,orthorhombic(C_(4)H_(9)NH_(3))_(2)PbI_(4) layered perovskite structure consists of an extended two-dimensional network of corner-sharing PbI_(6) octahedron.Single layer perovskite sheets of distorted PbI_(6) octahedron alternated with protonated n-butylammonium cation bilayers,which offers many advantages and provides the possibility of forming a gas sensor device based on the change of resistances.Density functional theory(DFT)simulations regarding the adsorption energy revealed that this organicinorganic hybrid perovskite compound has excellent selectivity toward p-xylene compared with other gases including C_(2)H_(5)OH,C_(6)H_(6),CH_(2)Cl_(2),HCHO,CH_(3)COCH_(3) and C_(7)H_(8).The calculation of electron density,density of states and electron density difference showed the sensing mechanism of p-C_(8)H_(10) is mainly derived from physical adsorption-desorption in view of electron transfer.展开更多
基金supported by the National Natural Science Foundation of China [12372078]Sixth Phase of Jiangsu Province"333 High Level Talent Training Project"Second Level Talents State Key Laboratory of Mechanics and Control of Mechanical Structures (Nanjing University of Aeronautics and astronautics [MCMS-E-0422G04].
文摘Identification of magnitude and orientation for spatially applied loading is highly desired in the fields of not only the machinery components but also human-machine interaction.Despite the fact that the 3-axis force sensor with different structures has been proposed to measure the spatial force,there are still some common limitations including the multi-step manufacturing-assembly processes and complicated testing of decoupling calibration.Here,we propose a rapid fabrication strategy with low-cost to achieve high-precision 3-axis force sensors.The sensor is designed to compose of structural Maltese cross base and sensing units.It is directly fabricated within one step by a hybrid 3D printing technology combining deposition modeling(FDM)with direct-ink-writing(DIW).In particular,a machine learning(ML)model is used to convert the strain signal to the force components.Instead of a mount of calibration tests,this ML model is trained by sufficient simulation data based on programmed batch finite element modeling.This sensor is capable of continuously identifying a spatial force with varying magnitude and orientation,which successfully quantify the applied force of traditional Chinese medicine physiotherapy including Gua Sha and massage.This work provides insight for design and rapid fabrication of multi-axis force sensors,as well as potential applications.
基金Project(20775010)supported by the National Natural Science Foundation of ChinaProject(208095)supported by the Key Project ofMinistry of Education,China+1 种基金Project(07A006)supported by the Scientific Research Fund of Hunan Provincial Education Department,ChinaProject(07JJ3020)supported by Hunan Provincial Natural Science Foundation of China
文摘A novel technique of immobilizing indicator dyes by electrostatic adsorption and covalent bonding to fabricate optical sensors was developed.3-Amino-9-ethylcarbazole(AEC)was attached to the outmost surface of quartz glass slide via aminosilanizing the slide,crosslinking chitosan,adsorbing Au nanoparticle,self-assembling HS(CH2)11OH,and coupling AEC.Thus, an AEC-immobilized optical sensor was obtained.The sensor exhibits a wide linear response range from 7.0×10- 7to 1.0×10 -4 mol/L and a correlation coefficient of 0.995 9 for the detection of 2-nitrophenol.The detection limit and response time of the sensor are 1.0×10- 7mol/L and less than 10 s,respectively.The fluorescence intensity of the used sensor can be restored to the blank value by simply rinsing with blank buffer.A very effective matrix for immobilizing indicator dye is provided by the proposed technique, which is adaptable to other indicator dyes with amino groups besides AEC.
基金the financial support from National Natural Science Foundation of China (No. 22102141)the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)+2 种基金Nature Science Foundation of Jiangsu Province No.BK20190905Project for Science and Technology of Yangzhou(No. YZ2020067)the open funds of the Ministry of Education Key Lab for Avian Preventive Medicine (No. YF202020)。
文摘In this article, we used the self-excitation and self-inductance characteristics of polyvinylidene fluoride(PVDF) piezoelectric materials, combined with the powerful signal processing and calculation analysis capabilities of integrated circuits, for the first time to explore a set of microcantilever sensor "readout system" without additional driver(self-driving) and can realize self-sensing external signal(self-sensing).It was successfully applied to the unlabeled detection of avian influenza virus(AIV) H9N_(2). The specific force of the antigen-antibody complexes on the surface of the microcantilever leads to the change of the stress of the cantilever, which drives the constructed detection device, and does not require an additional excitation source to drive it, that is, the self-driving part. At the same time, due to the movement of piezoelectric charges in the film caused by the positive piezoelectric effect of the PVDF film, self-inductive charges are generated on the surface of the sensor dielectric. The charge signal is converted into a voltage signal, and the sensing part is completed, that is, self-sensing. The immunosensor has a linear range of100-1000 ng/m L with a detection limit of 2.9 ng/m L. The method will also open up a new avenue for the detection of other analytes based on antigen-antibody responses.
基金supported by Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) (YX03001)Jiangsu Province Double Innovation Talent Program (090300014001)Nanjing University of Posts & Telecommunications (NY212004)
文摘A three-dimensional （3D） metal-organic framework （MOF） ZnL＇O.5H20＂O.75DMF （H2L=9-（pyridin-4-yl）-9H-carbazole- 3,6-dicarboxylic acid, DMF=N,N-dimethylformamide） has been synthesized under solvotherrnal condition. Crystal structure analysis shows that, in ZnL, each dinuclear Zn2（COO）2 unit is doubly-bridged to the other two by the carbazole moieties to form the 1D chains, which are further connected together by pyridine moieties to lead to the 3D framework. ZnL exhibits both high structural stability and good luminescent stability in water with the pH range of 4-10. ZnL displays the luminescent quenching response for Fe3＋ in water with good linear correlation between the quenching efficiency and the concentration with Ksv of 10800 M 1 in the low concentration range of 0-0.1 mM. Interestingly, it is observed that the sensing performance for Fe3＋ is stable in the pH range of 4-9, enabling ZnL to detect Fe3＋ ions in weak acidic and weak basic solutions.
基金financially supported by the Natural Science Foundation of Hebei(Nos.F2020202027 and F2020202067)the Major National Science and Technology Special Projects(No.2016ZX02301003-004-007)+1 种基金the National Natural Science Foundation of China(No.21271139)the Natural Science Foundation of Tianjin(No.17JCTPJC54500)。
文摘P-xylene(p-C_(8)H_(10))is extremely harmful and dangerous to human health due to high toxicity and strong carcinogenicity.Exploring sensitive material to effectively detect p-xylene is of importance.In this paper,perovskite single crystal(C_(4)H_(9)NH_(3))_(2)PbI_(4) has been successfully synthesized via solution method.The obtained product was analyzed by single crystal X-ray diffraction.With the space group Pbca,orthorhombic(C_(4)H_(9)NH_(3))_(2)PbI_(4) layered perovskite structure consists of an extended two-dimensional network of corner-sharing PbI_(6) octahedron.Single layer perovskite sheets of distorted PbI_(6) octahedron alternated with protonated n-butylammonium cation bilayers,which offers many advantages and provides the possibility of forming a gas sensor device based on the change of resistances.Density functional theory(DFT)simulations regarding the adsorption energy revealed that this organicinorganic hybrid perovskite compound has excellent selectivity toward p-xylene compared with other gases including C_(2)H_(5)OH,C_(6)H_(6),CH_(2)Cl_(2),HCHO,CH_(3)COCH_(3) and C_(7)H_(8).The calculation of electron density,density of states and electron density difference showed the sensing mechanism of p-C_(8)H_(10) is mainly derived from physical adsorption-desorption in view of electron transfer.
