目的：探讨血清钙、C-反应蛋白（ C-reactive protein， CRP）及血清淀粉酶样蛋白A（ serum amylase like protein A ， SAA）水平对重症急性胰腺炎（ severe acute pancreatitis ， SAP）的早期预测价值。方法120例急性胰腺炎患者，分...目的：探讨血清钙、C-反应蛋白（ C-reactive protein， CRP）及血清淀粉酶样蛋白A（ serum amylase like protein A ， SAA）水平对重症急性胰腺炎（ severe acute pancreatitis ， SAP）的早期预测价值。方法120例急性胰腺炎患者，分为轻症（ MAP）组91例，SAP组29例，同期健康体检者61例为对照组；比较三组血清钙、SAA和CRP水平。结果 MAP和SAP组CRP和SAA水平均较对照组显著升高，第2天达到峰值，SAP组显著高于MAP组；两组血清钙水平显著低于对照组，SAP组显著低于MAP组。三者联合测定的诊断敏感度96．9％和特异度97．4％。结论动态测定血清钙、SAA和CRP水平对评估SAP具有重要的临床价值。展开更多
Aim: To explore the research progress of echocardiography combined with blood-related detection indicators in the diagnosis and treatment of Kawasaki disease in children. By collecting relevant literature reports, ech...Aim: To explore the research progress of echocardiography combined with blood-related detection indicators in the diagnosis and treatment of Kawasaki disease in children. By collecting relevant literature reports, echocardiography and several blood-related detection indicators such as SAA, IL-6, PCT and CRP were screened out. It has good clinical application value in the clinical diagnosis and treatment of Kawasaki disease in children, but there is no report on the application of echocardiography combined with blood SAA, IL-6, PCT and CRP detection in the diagnosis and treatment of Kawasaki disease in children. The author intends to explore the role of echocardiography combined with blood SAA, IL-6, PCT and CRP detection in the diagnosis and treatment of Kawasaki disease in children, hoping to achieve better results.展开更多
Objective:To investigate the correlation between interleukin-6(IL-6),serum amyloid A(SAA),C-reactive protein(CRP)and exertional heat stroke in rats.Methods:A total of 90 adult Sprague-Dawley rats without specific path...Objective:To investigate the correlation between interleukin-6(IL-6),serum amyloid A(SAA),C-reactive protein(CRP)and exertional heat stroke in rats.Methods:A total of 90 adult Sprague-Dawley rats without specific pathogens were randomly divided into three groups:control group,classical group and exertion group,with 30 rats in each group.The control group was maintained at a temperature of(26±1)℃and humidity of(60±5)%,while the classical and exertion groups were exposed to a temperature of(40±0.5)℃and humidity of(70±5)%.Additionally,the exertion group underwent treadmill running under these conditions.The levels of IL-6,SAA,and CRP in the three groups were assessed and compared at various time points:before modeling,immediately after onset,and at 2,4,and 8 h after onset.Furthermore,Spearman correlation analysis was employed to examine.Results:The findings from the repeated measures analysis of variance indicated significant variations in the levels of IL-6,SAA,and CRP across the three groups(P<0.05).Both the classic and exertion groups exhibited higher levels of IL-6,SAA,and CRP compared to the control group,with the exertion group demonstrating even higher levels than the classic group(P<0.05).Additionally,Spearman correlation analysis revealed a positive correlation between the onset of heat stroke and the levels of IL-6,SAA,and CRP at the onset,as well as at 2,4,and 8 h post-onset(P<0.05).Furthermore,the types of heat stroke were found to be positively correlated with the levels of IL-6,SAA and CRP(P<0.05).Conclusion:The initiation and nature of heat stroke in rats are significantly associated with the concentrations of IL-6,SAA,and CRP.The concentrations of IL-6,SAA,and CRP within 8 h of onset can reliably forecast the occurrence of heat stroke in rats,serving as a basis for distinguishing classical heat stroke from exertional heat stroke.Nevertheless,the predictive and differentiating efficacy may diminish as the onset time prolongs.展开更多
文摘目的：探讨血清钙、C-反应蛋白（ C-reactive protein， CRP）及血清淀粉酶样蛋白A（ serum amylase like protein A ， SAA）水平对重症急性胰腺炎（ severe acute pancreatitis ， SAP）的早期预测价值。方法120例急性胰腺炎患者，分为轻症（ MAP）组91例，SAP组29例，同期健康体检者61例为对照组；比较三组血清钙、SAA和CRP水平。结果 MAP和SAP组CRP和SAA水平均较对照组显著升高，第2天达到峰值，SAP组显著高于MAP组；两组血清钙水平显著低于对照组，SAP组显著低于MAP组。三者联合测定的诊断敏感度96．9％和特异度97．4％。结论动态测定血清钙、SAA和CRP水平对评估SAP具有重要的临床价值。
文摘Aim: To explore the research progress of echocardiography combined with blood-related detection indicators in the diagnosis and treatment of Kawasaki disease in children. By collecting relevant literature reports, echocardiography and several blood-related detection indicators such as SAA, IL-6, PCT and CRP were screened out. It has good clinical application value in the clinical diagnosis and treatment of Kawasaki disease in children, but there is no report on the application of echocardiography combined with blood SAA, IL-6, PCT and CRP detection in the diagnosis and treatment of Kawasaki disease in children. The author intends to explore the role of echocardiography combined with blood SAA, IL-6, PCT and CRP detection in the diagnosis and treatment of Kawasaki disease in children, hoping to achieve better results.
文摘Objective:To investigate the correlation between interleukin-6(IL-6),serum amyloid A(SAA),C-reactive protein(CRP)and exertional heat stroke in rats.Methods:A total of 90 adult Sprague-Dawley rats without specific pathogens were randomly divided into three groups:control group,classical group and exertion group,with 30 rats in each group.The control group was maintained at a temperature of(26±1)℃and humidity of(60±5)%,while the classical and exertion groups were exposed to a temperature of(40±0.5)℃and humidity of(70±5)%.Additionally,the exertion group underwent treadmill running under these conditions.The levels of IL-6,SAA,and CRP in the three groups were assessed and compared at various time points:before modeling,immediately after onset,and at 2,4,and 8 h after onset.Furthermore,Spearman correlation analysis was employed to examine.Results:The findings from the repeated measures analysis of variance indicated significant variations in the levels of IL-6,SAA,and CRP across the three groups(P<0.05).Both the classic and exertion groups exhibited higher levels of IL-6,SAA,and CRP compared to the control group,with the exertion group demonstrating even higher levels than the classic group(P<0.05).Additionally,Spearman correlation analysis revealed a positive correlation between the onset of heat stroke and the levels of IL-6,SAA,and CRP at the onset,as well as at 2,4,and 8 h post-onset(P<0.05).Furthermore,the types of heat stroke were found to be positively correlated with the levels of IL-6,SAA and CRP(P<0.05).Conclusion:The initiation and nature of heat stroke in rats are significantly associated with the concentrations of IL-6,SAA,and CRP.The concentrations of IL-6,SAA,and CRP within 8 h of onset can reliably forecast the occurrence of heat stroke in rats,serving as a basis for distinguishing classical heat stroke from exertional heat stroke.Nevertheless,the predictive and differentiating efficacy may diminish as the onset time prolongs.
