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CRYSTALLOGRAPHIC STUDY ON HIGHLY STABLE HUMAN INSULINS(Ⅱ)——CRYSTALLIZATION AND PRELIMINARY CRYSTALLOGRAPHIC STUDY OF A21-GLY MUTANT
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作者 金雷 黄伟军 +3 位作者 张英 王大成 L. LANGKJAER J. MARKUSSEN 《Chinese Science Bulletin》 SCIE EI CAS 1992年第15期1302-1305,共4页
Ⅰ. INTRODUCTIONThe chemical stability of human insulin preparations is directly related to the residue of A21-Asn at C-terminal of A chain and can be distinctly increased by substituting the A21 residue in the way of... Ⅰ. INTRODUCTIONThe chemical stability of human insulin preparations is directly related to the residue of A21-Asn at C-terminal of A chain and can be distinctly increased by substituting the A21 residue in the way of protein engineering. Studying the fine three-dimensional structures 展开更多
关键词 human INSULIN a21-gly MUTANT CRYSTALLIZATION high stability.
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