Background G-protein–coupled receptor kinases (GRKs) play important roles in cardiac hypertrophy and heart failure. The role of GRK4 in hypertension has been well demonstrated, but little is known in cardiac ischemic...Background G-protein–coupled receptor kinases (GRKs) play important roles in cardiac hypertrophy and heart failure. The role of GRK4 in hypertension has been well demonstrated, but little is known in cardiac ischemic injury. In the present study, we explore if and how GRK4 regulates cardiomyocyte autophagy and influence the prognosis of myocardial infarction (MI).展开更多
文摘Background G-protein–coupled receptor kinases (GRKs) play important roles in cardiac hypertrophy and heart failure. The role of GRK4 in hypertension has been well demonstrated, but little is known in cardiac ischemic injury. In the present study, we explore if and how GRK4 regulates cardiomyocyte autophagy and influence the prognosis of myocardial infarction (MI).
