The articular cartilage （AC） can be seen as a biphasic poroelastic material. The cartilage deformation under compression mainly leads to an interstitial fluid flow in the porous solid phase. In this paper, an analyt...The articular cartilage （AC） can be seen as a biphasic poroelastic material. The cartilage deformation under compression mainly leads to an interstitial fluid flow in the porous solid phase. In this paper, an analytical poroelastic model for the AC under laboratorial mechanical testing is developed. The solutions of interstitial fluid pressure and velocity are obtained. The results show the following facts. （i） Both the pressure and fluid velocity amplitudes are proportional to the strain loading amplitude. （ii） Both the amplitudes of pore fluid pressure and velocity in the AC depend more on the loading amplitude than on the frequency. Thus, in order to obtain the considerable fluid stimulus for the AC cell responses, the most effective way is to increase the loading amplitude rather than the frequency. （iii） Both the interstitiM fluid pressure and velocity are strongly affected by permeability variations. This model can be used in experimental tests of the parameters of AC or other poroelastic materials, and in research of mechanotransduction and injury mechanism involved interstitial fluid flow.展开更多
本文介绍了数字集成电路测试系统的工作原理,提出了两种AC参数的定量测试方法:二分步长测试和on the fly测试。通过预先设置驱动/比较时间和测试向量、执行功能测试、从结果存储器获取"通过/失效"结果,可以计算出AC参数的量...本文介绍了数字集成电路测试系统的工作原理,提出了两种AC参数的定量测试方法:二分步长测试和on the fly测试。通过预先设置驱动/比较时间和测试向量、执行功能测试、从结果存储器获取"通过/失效"结果,可以计算出AC参数的量值。测试一个AC参数,二分步长测试方法需多次执行测试向量,on the fly测试法仅需执行一次测试,但要求测试系统具备on the fly资源。两种方法的测试精度相同,均能有效解决AC参数的定量测试,后者更适于高速器件的测试。文中介绍的方法在BC3192集成电路测试系统上对MAX488器件进行测试,在250 kHz的测试频率下,两种方法测得的tSKEW参数结果近似相等,具有很好的一致性。展开更多
基金Project supported by the National Natural Science Foundation of China(Nos.11632013,11472185,and 11702183)the Natural Science Foundation of Shanxi Province(No.2016021145)+1 种基金the Program for the OIT of Higher Learning Institutions of Shanxi,the State Key Laboratory of Fine Chemicals(No.KF 1511)the Scientific and Technological Innovation Projects of Colleges and Universities in Shanxi Province(No.2017135)
文摘The articular cartilage （AC） can be seen as a biphasic poroelastic material. The cartilage deformation under compression mainly leads to an interstitial fluid flow in the porous solid phase. In this paper, an analytical poroelastic model for the AC under laboratorial mechanical testing is developed. The solutions of interstitial fluid pressure and velocity are obtained. The results show the following facts. （i） Both the pressure and fluid velocity amplitudes are proportional to the strain loading amplitude. （ii） Both the amplitudes of pore fluid pressure and velocity in the AC depend more on the loading amplitude than on the frequency. Thus, in order to obtain the considerable fluid stimulus for the AC cell responses, the most effective way is to increase the loading amplitude rather than the frequency. （iii） Both the interstitiM fluid pressure and velocity are strongly affected by permeability variations. This model can be used in experimental tests of the parameters of AC or other poroelastic materials, and in research of mechanotransduction and injury mechanism involved interstitial fluid flow.
文摘本文介绍了数字集成电路测试系统的工作原理,提出了两种AC参数的定量测试方法:二分步长测试和on the fly测试。通过预先设置驱动/比较时间和测试向量、执行功能测试、从结果存储器获取"通过/失效"结果,可以计算出AC参数的量值。测试一个AC参数,二分步长测试方法需多次执行测试向量,on the fly测试法仅需执行一次测试,但要求测试系统具备on the fly资源。两种方法的测试精度相同,均能有效解决AC参数的定量测试,后者更适于高速器件的测试。文中介绍的方法在BC3192集成电路测试系统上对MAX488器件进行测试,在250 kHz的测试频率下,两种方法测得的tSKEW参数结果近似相等,具有很好的一致性。
