Acid regurgitation is a common symptom in digestive system diseases which is mainly caused by emotions,diet,and other factors.It is related to gastroesophageal reflux disease,chronic gastritis,and other diseases in We...Acid regurgitation is a common symptom in digestive system diseases which is mainly caused by emotions,diet,and other factors.It is related to gastroesophageal reflux disease,chronic gastritis,and other diseases in Western medicine.According to modem medical research,acid reflux is related to Helicobacter pylori(HP)infection,weak effect of anti-reflux barrier,decreased clearance of esophageal acid,dysfunction of esophageal mucosal barrier,strong stimulation of reflux on esophageal mucosal wall,and other factors[1].It can be divided into four types which are heat,cold,food stagnation,and yin deficiency It is often accompanied by vomiting,heartbum,stomachache,and other symptoms.Clinically,it is a mixture of cold and heat,as well as excess and deficiency.Professor Du's self-made method of“first soothing,second reducing,and third harmonizmg”(soothing liver and stomach,relieving stomach qi,and neutralizing stomach acid)is used to treat both,symptoms and the root causes.The commonly used prescriptions are left-running metal pill,cuttlefish bone and fritillaria powder,calcined ark shell,oyster shell,etc.展开更多
Background: Pyrosis and regurgitation are the cardinal symptoms of gastroesophageal reflux disease. Severalherbs have been used for treating gastrointestinal disorders worldwide. This systematic review was conducted t...Background: Pyrosis and regurgitation are the cardinal symptoms of gastroesophageal reflux disease. Severalherbs have been used for treating gastrointestinal disorders worldwide. This systematic review was conducted toinvestigate the effects of medicinal herbs on gastroesophageal reflux disease and adverse events. Methods:MEDLINE (via PubMed;The United States National Library of Medicine, USA), Scopus, ScienceDirect,Cochrane Central Register of Controlled Trials, Web of Science, Magiran, and Scientific Information Databasewere systematically searched for human studies, without a time frame, using medical subject heading terms such as“gastroesophageal reflux disease”, “reflux”, “esophagitis” and “herbs”. Manual searches completed the electronicsearches. Results: Thirteen randomized controlled trials were identified, including 1,164 participants from 1,509publications. In comparing herbal medicine to placebo, there were no significant differences in terms of heartburn(P = 0.23 and 0.48), epigastric or abdominal pain (P = 0.35), reflux syndrome (P = 0.12), and effective rate (P =0.60), but there was a significant difference in terms of acid regurgitation (P = 0.01). In comparing herbal medicineto drugs, there was a significant difference in terms of effective rate (P = 0.001), and there was one trial thatreported a significant difference in terms of epigastric pain (P = 0.00001). Also, in comparing herbal medicine todrugs, there were no significant differences in terms of acid regurgitation (P = 0.39). Conclusion: Thismeta-analysis showed that herbal medicines are effective in treating gastroesophageal reflux disease. Furtherstandardized researches with a large-scale, multicenter, and rigorous design are needed.展开更多
文摘Acid regurgitation is a common symptom in digestive system diseases which is mainly caused by emotions,diet,and other factors.It is related to gastroesophageal reflux disease,chronic gastritis,and other diseases in Western medicine.According to modem medical research,acid reflux is related to Helicobacter pylori(HP)infection,weak effect of anti-reflux barrier,decreased clearance of esophageal acid,dysfunction of esophageal mucosal barrier,strong stimulation of reflux on esophageal mucosal wall,and other factors[1].It can be divided into four types which are heat,cold,food stagnation,and yin deficiency It is often accompanied by vomiting,heartbum,stomachache,and other symptoms.Clinically,it is a mixture of cold and heat,as well as excess and deficiency.Professor Du's self-made method of“first soothing,second reducing,and third harmonizmg”(soothing liver and stomach,relieving stomach qi,and neutralizing stomach acid)is used to treat both,symptoms and the root causes.The commonly used prescriptions are left-running metal pill,cuttlefish bone and fritillaria powder,calcined ark shell,oyster shell,etc.
文摘Background: Pyrosis and regurgitation are the cardinal symptoms of gastroesophageal reflux disease. Severalherbs have been used for treating gastrointestinal disorders worldwide. This systematic review was conducted toinvestigate the effects of medicinal herbs on gastroesophageal reflux disease and adverse events. Methods:MEDLINE (via PubMed;The United States National Library of Medicine, USA), Scopus, ScienceDirect,Cochrane Central Register of Controlled Trials, Web of Science, Magiran, and Scientific Information Databasewere systematically searched for human studies, without a time frame, using medical subject heading terms such as“gastroesophageal reflux disease”, “reflux”, “esophagitis” and “herbs”. Manual searches completed the electronicsearches. Results: Thirteen randomized controlled trials were identified, including 1,164 participants from 1,509publications. In comparing herbal medicine to placebo, there were no significant differences in terms of heartburn(P = 0.23 and 0.48), epigastric or abdominal pain (P = 0.35), reflux syndrome (P = 0.12), and effective rate (P =0.60), but there was a significant difference in terms of acid regurgitation (P = 0.01). In comparing herbal medicineto drugs, there was a significant difference in terms of effective rate (P = 0.001), and there was one trial thatreported a significant difference in terms of epigastric pain (P = 0.00001). Also, in comparing herbal medicine todrugs, there were no significant differences in terms of acid regurgitation (P = 0.39). Conclusion: Thismeta-analysis showed that herbal medicines are effective in treating gastroesophageal reflux disease. Furtherstandardized researches with a large-scale, multicenter, and rigorous design are needed.
