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Clinical Study on the Treatment of Senile Alzheimer’s Dementia with Sodium Oligomannate Combined with Memantine Hydrochloride
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作者 Jian Zhao Xi Li +1 位作者 Xuelian Jia Ganke Gao 《Journal of Clinical and Nursing Research》 2024年第10期208-217,共10页
Objective:To analyze the clinical effects of sodium oligomannate combined with memantine hydrochloride in the treatment of senile Alzheimer’s dementia.Methods:Sixty-eight cases of Alzheimer’s dementia treated at the... Objective:To analyze the clinical effects of sodium oligomannate combined with memantine hydrochloride in the treatment of senile Alzheimer’s dementia.Methods:Sixty-eight cases of Alzheimer’s dementia treated at the Second People’s Hospital of Fujian University of Traditional Chinese Medicine from March 2020 to March 2022 were selected as the study subjects.The patients were divided into two groups based on different treatment methods:the control group(treated with memantine hydrochloride,34 cases)and the treatment group(treated with sodium oligomannate+memantine hydrochloride,34 cases).Cognitive function,activities of daily living,neurotransmitters,serum intestinal flora metabolic markers,inflammatory factors,neurotrophic factors,and adverse reactions were compared between the two groups.Results:The treatment group showed better cognitive function,quality of life scores,and levels of relevant metabolic markers in the body compared to the control group,with statistically significant differences(P<0.05).The incidence of adverse reactions between the two groups(treatment group:2%;control group:4%)was not statistically significant(χ^(2)=0.731,P=0.393).Conclusion:Sodium oligomannate combined with memantine hydrochloride has better efficacy than the control group for treating senile Alzheimer’s dementia.It significantly improves and restores cognitive function and daily living abilities,benefits neurotransmitter secretion and internal regulation,upregulates the expression of neurotrophic factors,and has fewer adverse reactions,making it a treatment worthy of further clinical promotion and application. 展开更多
关键词 senile Alzheimer’s dementia Sodium oligomannate Memantine hydrochloride Cognitive function TREATMENT
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实验性ACST大鼠肺、肝、腹腔巨噬细胞分泌TNF、IL-1的变化及活血清解灵的调节作用 被引量:4
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作者 崔华雷 秦明放 +3 位作者 姚智 卢奕 李会强 鲁焕章 《中国中西医结合外科杂志》 CAS 2001年第1期39-41,共3页
目的 :观察肝脏枯否细胞、肺泡及腹腔巨噬细胞在急性重症胆管炎 (ACST)时分泌TNF、IL 1的变化 ,以及应用活血清解灵进行治疗的调节作用。 方法 :通过胆总管远端结扎 ,近端注入菌液并封闭的方法 ,造成大鼠ACST模型。采用单纯胆管减压、... 目的 :观察肝脏枯否细胞、肺泡及腹腔巨噬细胞在急性重症胆管炎 (ACST)时分泌TNF、IL 1的变化 ,以及应用活血清解灵进行治疗的调节作用。 方法 :通过胆总管远端结扎 ,近端注入菌液并封闭的方法 ,造成大鼠ACST模型。采用单纯胆管减压、胆管减压配合抗生素、胆管减压配合活血清解灵三种不同方法治疗。分离和培养肺泡巨噬细胞、腹腔巨噬细胞、肝脏枯否细胞 ,收集培养上清液 ,采用MTT法测定细胞因子活性。 结果 :模型组上述巨噬细胞分泌IL 1、TNF的水平显著升高(P <0 0 0 1) ,中药治疗组虽明显高于假手术对照组 ,但明显低于ACST模型组 (P <0 0 5 ) ,减压组和氨苄组与造模组无差异 (P>0 0 5 )。 结论 :活血清解灵能抑制ACST时炎性细胞因子的过度分泌 。 展开更多
关键词 巨噬细胞 急性重症胆管炎 细胞因子 活血清解灵 acst TNF IL-1
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重症急性胆管炎(ACST)96例的救治 被引量:2
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作者 岳茂兴 李学彪 李成林 《伤残医学杂志》 2004年第2期19-21,共3页
目的:本文探讨手术救治由胆石症导致的重症急性胆管炎(ACST)的经验体会.方法:本组男51例,女45例.行胆总管切开取石、T管引流术、胆囊切除术73例,行胆囊造瘘术,T管引流术13例,行胆肠吻合术3例,行胆总管、空肠Rou—Y吻合术6例,行胆总管囊... 目的:本文探讨手术救治由胆石症导致的重症急性胆管炎(ACST)的经验体会.方法:本组男51例,女45例.行胆总管切开取石、T管引流术、胆囊切除术73例,行胆囊造瘘术,T管引流术13例,行胆肠吻合术3例,行胆总管、空肠Rou—Y吻合术6例,行胆总管囊肿切除、结石取出、肝总管残端与空肠Roux-Y吻合术1例.其中近4年来并发MOF的22例患者采用了“四大一支持”综合疗法.结果:本组96例均行手术治疗,重症急性胆管炎并发多器官功能衰竭22例,占22.91%,死亡9例。总死亡率为9.61%.结论:重症急性胆管炎早期进行手术减压是降低死亡率非常重要的措施之一.当并发MOF时要给予强有力的“四大一支持”综合疗法.即短程大剂量山莨菪碱;短程大剂量地塞米松;大剂量应用抗厌氧菌和抗需氧茵抗生素联合正确应用;腹腔灌洗液清洗腹腔;一支持即完全的代谢营养支持.该疗法有助于ACST病人渡过手术关,在致死性的触发病因去除后,促进器官功能发生逆转最终使患者获得痊愈. 展开更多
关键词 急性胆管炎 acst 多器官功能衰竭 胆道 营养支持
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226例老年ACST高危因素分析和预后评估 被引量:1
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作者 胡国斌 金凌应 邬四明 《中级医刊》 1998年第1期17-19,共3页
文中分析老年人患重症急性胆管炎的高危因素,并对其预后作出评估。收集老年AC-ST226例,采用卡方检验进行回顾性分析。确定病人年龄在70岁以上、病史超过10年、休克收缩压<70mmHg、脉率>120次/分、血白细胞计数>20×109/L、... 文中分析老年人患重症急性胆管炎的高危因素,并对其预后作出评估。收集老年AC-ST226例,采用卡方检验进行回顾性分析。确定病人年龄在70岁以上、病史超过10年、休克收缩压<70mmHg、脉率>120次/分、血白细胞计数>20×109/L、体温>39℃或<36℃、合并其他器官器质性病变、有一次以上胆管手术史、术前休克未纠正、入院距手术时间>24小时及胆汁为脓性、胆道压力增高等11项指标为本病的高危因素。采用上述方法对本组226例进行评估,显示-4分以上预后较好,-5~-8分病死率逐渐增加,-9分以下病死率达100%。 展开更多
关键词 胆管炎 预后 acst 高危因素 老年人
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ACST94例诊治分析
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作者 朱博 夏灏 +1 位作者 李成炎 张明 《长江大学学报(自然科学版)》 CAS 2011年第12期178-179,共2页
目的:总结重症急性胆管炎(ACST)的诊治经验,以降低死亡率。方法:回顾分析医院近10年来收治符合ACST诊断标准的94例患者的临床资料。结果:94例患者中,死亡12例,死亡率12.8%,明显低于文献报告数据;其中手术组80例,死亡7例,死亡率8.8%;非... 目的:总结重症急性胆管炎(ACST)的诊治经验,以降低死亡率。方法:回顾分析医院近10年来收治符合ACST诊断标准的94例患者的临床资料。结果:94例患者中,死亡12例,死亡率12.8%,明显低于文献报告数据;其中手术组80例,死亡7例,死亡率8.8%;非手术组14例,死亡5例,死亡率35.7%,手术组和非手术组存在显著差异。结论:早期诊断,及时手术是降低病死率的关键,同时必须注意手术的有效性和彻底性。 展开更多
关键词 acst 诊断 治疗 手术
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38例胆总管末端结石并ACST的内镜治疗
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作者 宫铭 谯丽莉 张启华 《山东医药》 CAS 北大核心 2005年第29期62-63,共2页
关键词 胆总管末端结石 内镜治疗 acst 十二指肠乳头括约肌切开术 重症急性胆管炎 结石嵌顿 取石术 内镜下
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The Study of G6PD in Erythrocyte and Lens in Senile and Presenile Cataract
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作者 Youzhao Chen, Linghua Zeng, Qiaoyun Ma, Wen Su, Wenshu Mao Eye Research Institute, Zhongshan Ophthalmic Center, Sun Yat-Sen University of Medical Sciences Guangzhou 510060, China 《眼科学报》 1992年第1期12-15,33,共5页
The G6PD activity of erythrocytes in 113 male patients with senile and presenile cataract and 86 controls, and G6PD activity of lens in 30 patients with senile cataract and 42 controls were reported. The cataractous g... The G6PD activity of erythrocytes in 113 male patients with senile and presenile cataract and 86 controls, and G6PD activity of lens in 30 patients with senile cataract and 42 controls were reported. The cataractous group had higher frequency of G6PD deficiency and lower average G6PD level in erythrocytes and lenses, but with out statistical significance. The frequency of G6PD deficiency of erythrocytes in presenile cataractous group was higher than that of senile cataractous group but with no statistic... 展开更多
关键词 senile cataract presenile cataract G6PD ERYTHROCYTE lens.
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ACST86例诊治体会
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作者 金全乐 马庆勇 《蚌埠医药》 1992年第2期19-20,共2页
重症急性阻管炎(ACST)是良性胆道疾患中最主要的死亡原因,因其能造成全身各个脏器的功能损害,死亡率高达50%以上,现就诊治中的体会分析讨论如下。
关键词 acst 诊断 治疗 重症急性阻管炎 手术方式
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ACST系列AC功率开关及其应用
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作者 邱振民 邱猛 《电子元器件应用》 2003年第2期28-29,58,共3页
ACST系列AC开关嵌入了Triac结构和高压嵌位器件,适合于用作驱动家电和工业系统电感性或电阻性负载。本文介绍ACST系列Ac开关的图形符号、命名方法及优点,重点介绍代表性器件ACST4-7S和ACST6-7S的特性及应用。
关键词 acst系列 AC功率开关 功率器件 acst6-7S
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Therapeutic effect of Cistanche deserticola on defecation in senile constipation rat model through stem cell factor/C-kit signaling pathway 被引量:25
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作者 Xia Zhang Fa-Juan Zheng Zhen Zhang 《World Journal of Gastroenterology》 SCIE CAS 2021年第32期5392-5403,共12页
BACKGROUND Constipation is one of the chronic gastrointestinal functional diseases.It seriously affects the quality of life.Cistanche deserticola(C.deserticola)can treat constipation obviously,but its mechanism has no... BACKGROUND Constipation is one of the chronic gastrointestinal functional diseases.It seriously affects the quality of life.Cistanche deserticola(C.deserticola)can treat constipation obviously,but its mechanism has not been clarified.We supposed that mechanism of it improved the intestinal motility by stimulating interstitial Cajal cells(ICC).Activation of the C-kit receptor on the surface of ICC is closely related to ICC function,and the stem cell factor(SCF)/C-kit signaling pathways plays an important role on it.To investigate the mechanism of how C.deserticola treats constipation,this study aimed to establish a constipation model in rats and explore the role of SCF/C-kit signaling pathway in the treatment.AIM To explore the SCF/C-kit signaling pathways in the role of C.deserticola for treatment of constipation by a constipation rat model.METHODS Forty-eight 8-mo-old Sprague–Dawley rats were divided into 4 groups by random weight method:Normal group(n=12),model group(n=12),C.deserticola group(n=12)and blocker group(n=12).The normal group received normal saline by gavage;the model group received loperamide by gavage;the blocker group received loperamide and C.deserticola by gavage,and STI571 was injected by intraperitoneally.During treatment,the weight,fecal granules and fecal quality were recorded every 10 d.On day 20 after model induction,the colon tissues of each group were removed.Hematoxylin and eosin staining was used to observe pathological changes.Expression levels of SCF,C-kit and Aquaporin genes were detected by immunohistochemistry,western blotting,and real-time-quantitative polymerase chain reaction.The colonic epithelial mitochondria and goblet cells were observed by transmission electron microscopy.RESULTS Compared with the normal group,as treatment progressed,the weight of rats in the model and blocker groups decreased significantly,the stool weight decreased,and the stool quality was dry(P<0.05).C.deserticola reversed the decrease in body weight and stool weight and improved stool quality.Histopathological analysis indicated that the colonic mucosal epithelium in the model group was incomplete,and the arrangement of the glands was irregular or damaged.Treatment with C.deserticola improved the integrity and continuity of the epithelial cells and regular arrangement of the glands.The blocking agents inhibited the effects of C.deserticola Immunohistochemistry and real-timequantitative polymerase chain reaction showed that expression of SCF and C-kit protein or genes in the colonic tissue of the model group was decreased(P<0.05),while treatment with C.deserticola increased protein or gene expression(P<0.05).Western blotting showed that expression of aquaporin APQ3 was increased,while the expression of Cx43 decreased in the model group.Treatment with C.deserticola inhibited expression of APQ3 and promoted expression of Cx43.Transmission electron microscopy showed that the mitochondria of the colonic epithelium in the model group were swollen and arranged disorderly,and microvilli were sparse.The condition was better in the C.deserticola group.Mice treated with STI571 blocker confirmed that blocking the SCF/C-kit pathway inhibited the improvement of constipation by C.deserticola.CONCLUSION C.deserticola improved defecation in rats with constipation,and the SCF/C-kit signaling pathway,which is a key link of ICC function,played an important role of the treatment. 展开更多
关键词 Cistanche deserticola senile constipation Stem cell factors C-KIT
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Central Venous Catheter-related Thrombosis in Senile Male Patients: New Risk Factors and Predictors 被引量:4
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作者 柳高 付治卿 +1 位作者 朱平 李世军 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2015年第3期445-449,共5页
Central venous catheterization(CVC)-related venous thrombosis is a common but serious clinical complication, thus prevention and treatment on this problem should be extensively investigated. In this research, we aim... Central venous catheterization(CVC)-related venous thrombosis is a common but serious clinical complication, thus prevention and treatment on this problem should be extensively investigated. In this research, we aimed to investigate the incidence rate of CVC-related venous thrombosis in senile patients and give a further discussion on the related risk factors and predictors. A total of 324 hospitalized senile male patients subjected to CVC were selected. Retrospective investigation and analysis were conducted on age, underlying diseases, clinical medications, catheterization position and side, catheter retention time, and incidence of CVC-related venous thrombosis complications. Basic laboratory test results during catheterization and thrombogenesis were also collected and analyzed. Among the 324 patients, 20 cases(6.17%) of CVC-related venous thrombosis were diagnoseds. The incidence rate of CVC-related venous thrombosis in subclavian vein catheterization was significantly lower than that in femoral vein catheterization(P〈0.01) and that in internal jugular vein catheterization(P〈0.05). No statistically significant difference was found between femoral vein catheterization and internal jugular vein catheterization(P〉0.05). Previous venous thrombosis history(P〈0.01), high lactate dehydrogenase level(P〈0.01), low high-density lipoprotein(HDL) level(P〈0.05), and low albumin level(P〈0.05) were found as risk factors or predictors of CVC-related venous thrombosis in senile male patients. Subclavian vein catheterization was the most appropriate choice among senile patients to decrease the incidence of CVC-related venous thrombosis. Previous venous thrombosis history, high lactate dehydrogenase level, low HDL level, and low albumin level were important risk factors in predicting CVC-related venous thrombosis. 展开更多
关键词 risk factors central venous catheterization-related venous thrombosis senile male patients
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Key determinants of misdiagnosis of tracheobronchial tuberculosis among senile patients in contemporary clinical practice:A retrospective analysis 被引量:8
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作者 Fei Tang Lian-Jun Lin +8 位作者 Shu-Liang Guo Wei Ye Xian-Kui Zha Yu Cheng Ying-Feng Wu Yue-Ming Wang Xiao-Mei Lyu Xiao-Yun Fan Li-Ping Lyu 《World Journal of Clinical Cases》 SCIE 2021年第25期7330-7339,共10页
BACKGROUND Tracheobronchial tuberculosis(TBTB)is a common subtype of pulmonary tuberculosis.Concomitant diseases often obscure the diagnosis of senile TBTB.AIM To characterize senile patients with TBTB and to identify... BACKGROUND Tracheobronchial tuberculosis(TBTB)is a common subtype of pulmonary tuberculosis.Concomitant diseases often obscure the diagnosis of senile TBTB.AIM To characterize senile patients with TBTB and to identify the potential causes of misdiagnosis.METHODS One hundred twenty patients with senile TBTB who were admitted to the Anhui Chest hospital between May 2017 and May 2019 were retrospectively analyzed.Patients were classified as diagnosed group(n=58)and misdiagnosed group(n=62).Clinical manifestations,laboratory results,radiographic data,and endoscopic findings were compared between the two groups.RESULTS Patients in the misdiagnosed group were most commonly diagnosed as pulmonary tuberculosis(non-TBTB,29/62,46.8%),general pneumonia(9/62,14.5%),chronic obstructive pulmonary disease(8/62,12.9%),and tracheobronchial carcinoma(7/62,11.3%).The time elapsed between disease onset and confirmation of diagnosis was significantly longer in the misdiagnosed group[median(first quartile,third quartile):6.32(4.94,16.02)mo vs 3.73(2.37,8.52)mo].The misdiagnosed group had lower proportion of patients who underwent bronchoscopy[33.87%(21/62)vs 87.93%(51/58)],chest computed tomography(CT)scan[69.35%(43/62)vs 98.28%(57/58)],and those who showed CT signs of tuberculosis[27.91%(12/62)vs 50%(29/58)]as compared to that in the diagnosed group(P<0.05).There were no significant between-group differences with respect to age,gender,occupation,clinical manifestations,or prevalence of comorbid chronic diseases(P>0.05).CONCLUSION Insufficient or inaccurate radiographic or bronchoscopic assessment was the predominant cause of delayed diagnosis of TBTB.Increased implementation and better interpretation of CT scan and early implementation of bronchoscopy can help reduce misdiagnosis of senile TBTB. 展开更多
关键词 senile tracheobronchial tuberculosis MISDIAGNOSIS Clinical characteristics Pulmonary tuberculosis TUBERCULOSIS
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The Clinical Study of a New Management Model Using Mobile Health for Senile Hypertension 被引量:2
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作者 Jian Shi Ping Wang Aimin Wang 《Health》 2019年第8期1087-1094,共8页
Objective: To evaluate a new management model using mobile health for senile hypertension. Methods: This medical service combined traditional medical treatment with Mobile Health. We use it to explore a new and effect... Objective: To evaluate a new management model using mobile health for senile hypertension. Methods: This medical service combined traditional medical treatment with Mobile Health. We use it to explore a new and effective model of elderly hypertension management and the most effective and lowest cost management crowd. According to the randomized controlled design of trial, 105 old hypertensive patients participated in the study voluntarily in the Qingdao Municipal Hospital were randomly divided into the experimental group (75 cases) and control group (30 cases). Experimental group is divided into geriatric specialist group (25 cases), general practitioner group (25 cases) and nurse group (25 cases). Blood pressure was administered in experimental (with the new model) and control groups (with the traditional model) for 2 months to compare their blood pressure and the decrease of them. Results: Blood pressure was compared between the two groups before and after administration. The systolic blood pressure (SBP) of experimental group is 162.44 ± 13.970 mmHg before administration. SBP of experimental group is 147.69 ± 13.509 mmHg after administration, the difference is statistically significant (P = 0.000). The diastolic blood pressure (DBP) of experimental group is 91.58 ± 10.822 mmHg before administration. DBP of experimental group is 84.64 ± 10.412 mmHg after administration, P = 0.003. SBP of control group is 159.93 ± 15.238 mmHg before administration. The systolic blood pressure of control group is 152.33 ± 14.115 (mmHg) after administration. P is 0.167 (P > 0.05). The difference was not statistically significant. DBP of control group is 94.73 ± 12.401 (mmHg) before administration. DBP of control group is 90.60 ± 11.115 (mmHg) after administration. P is 0.345 (P > 0.05). The difference was not statistically significant. The decrease of SBP of geriatric specialist group, general practitioner group and nurse group is 18.40 ± 11.764 mmHg, 14.47 ± 9.44 mmHg, 10.80 ± 6.026 mmHg. The difference was not statistically significant (P > 0.05). The decrease of DBP of geriatric specialist group, general practitioner group and nurse group is 9.33 ± 7.451 mmHg vs. 5.33 ± 6.287 mmHg vs. 6.13 ± 5.069 mmHg (P > 0.05). Conclusion: The new model is effective and it works well for controlling blood pressure of elderly hypertensive patients. Especially with the doctors and patients’ families, the management effect has been obviously improved. Medical interventions make the new model more scientific. The management of geriatric specialists, general practitioners and nurses is equally valid. 展开更多
关键词 senile HYPERTENSION MANAGEMENT MODEL MOBILE HEALTH
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Diagnosis related group grouping study of senile cataract patients based on E-CHAID algorithm 被引量:8
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作者 AiJing Luo Wei-Fu Chang +6 位作者 Zi-Rui Xin Hao Ling Jun-Jie Li Ping-Ping Dai Xuan-Tong Deng Lei Zhang Shao-Gang Li 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2018年第2期308-313,共6页
AIM: To figure out the contributed factors of the hospitalization expenses of senile cataract patients(HECP) and build up an area-specified senile cataract diagnosis related group(DRG) of Shanghai thereby formula... AIM: To figure out the contributed factors of the hospitalization expenses of senile cataract patients(HECP) and build up an area-specified senile cataract diagnosis related group(DRG) of Shanghai thereby formulating the reference range of HECP and providing scientific basis for the fair use and supervision of the health care insurance fund.METHODS: The data was collected from the first page of the medical records of 22 097 hospitalized patients from tertiary hospitals in Shanghai from 2010 to 2012 whose major diagnosis were senile cataract. Firstly, we analyzed the influence factors of HECP using univariate and multivariate analysis. DRG grouping was conducted according to the exhaustive Chi-squared automatic interaction detector(E-CHAID) model, using HECP as target variable. Finally we evaluated the grouping results using non-parametric test such as Kruskal-Wallis H test, RIV, CV, etc.RESULTS: The 6 DRGs were established as well as criterion of HECP, using age, sex, type of surgery and whether complications/comorbidities occurred as the key variables of classification node of senile cataract cases.CONCLUSION: The grouping of senile cataract cases based on E-CHAID algorithm is reasonable. And the criterion of HECP based on DRG can provide a feasible way of management in the fair use and supervision of medical insurance fund. 展开更多
关键词 diagnosis related group senile cataract hospitalization expenses E-CHAID algorithm
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State of the Places of Senile Dementia in the Old Hospice of the City of Lubumbashi 被引量:1
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作者 Fabrice Lele Mutombo Criss Koba Mjumbe +3 位作者 Isabelle Kasongo Omba Franck Omangelo Shongo Nora Mwamini Asani Beatrice Koba Bora 《Advances in Alzheimer's Disease》 2019年第4期39-46,共8页
The objective of this study was to describe the state of the scene of senile dementia in an intra-institutional environment in the city of Lubumbashi. We conducted a descriptive cross-sectional study, over a period of... The objective of this study was to describe the state of the scene of senile dementia in an intra-institutional environment in the city of Lubumbashi. We conducted a descriptive cross-sectional study, over a period of three months, from February 20 to May 20, 2016. The study population is made up of the residents of the 9 retirement institutions for senior citizens (old people’s home) which counts the city of Lubumbashi. Participation was voluntary with informed consent duly signed by the patient. The probable cases of dementia were detected through the CSI-D and the 5-word test. A predominance of Alzheimer’s was noted (76.92%) and most of them were widowed (69.23%). The mean age of the dementia population was 76.46 ± 9.87 years, while (69.23%) of the patients were out of school. In (23.08%) cases demented patients were male, with a sex ratio of 0.3. Nearly (46.15%) of the demented were drinking. It appears that (69.23%) of the dementias were hypertensive. There are associations between different risk factors and the presence of dementias. Alcohol with an OR (Odd Ratio) = 0.08 (95% CI [0.01 - 0.72], p < 0.05). In our environment, our results indicate a different situation with a much higher prevalence. 展开更多
关键词 STATE of Play senile Dementia OLD HOSPICE CITY of Lubumbashi/RD CONGO
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Sensory exotropia subsequent to senile cataract 被引量:1
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作者 LOU Ding-hua(楼定华) +3 位作者 XU Ye-sheng(许叶圣) LI Yu-min(李毓敏) 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第12期1220-1222,共3页
To evaluate the phacoemulsification and intraocular lens implantation in patients with sensory exotropia subsequent to senile cataract. The authors prospectively studied the role of phacoemulsification and intraocular... To evaluate the phacoemulsification and intraocular lens implantation in patients with sensory exotropia subsequent to senile cataract. The authors prospectively studied the role of phacoemulsification and intraocular lens implantation on 25 patients by observing visual acuity, ocular alignment, binocular vision and diplopia pre-, 1 month post- and 3 months post-operation. The patients underwent follow-up for three months. Postoperatively, one patient had a corrected visual acuity of 20/50, and 24 patients had 20/40 or better. The ocular alignment, binocular vision and diplopia were resolved spontaneously. Phacoemulsification and intraocular lens implantation performed together is effective on sensory exotropia subsequent to senile cataract. 展开更多
关键词 PHACOEMULSIFICATION senile cataract Sensory exotropia
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Determination of Carboplatin Dose by Area Under the Curve in Combination Chemotherapy for Senile Non-small Cell Lung Cancer 被引量:1
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作者 殷铁军 刘菁菁 +1 位作者 胡长耀 刘梦涛 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2007年第6期710-712,共3页
To preliminarily determine the appropriate dosage of carboplatin (CBP) at AUC of 5 mg-M1^-1·min^-1 in the combination chemotherapy for Chinese senile patients with non-small cell lung cancer (NSCLC). Thirty-f... To preliminarily determine the appropriate dosage of carboplatin (CBP) at AUC of 5 mg-M1^-1·min^-1 in the combination chemotherapy for Chinese senile patients with non-small cell lung cancer (NSCLC). Thirty-five Chinese senile patients with NSCLC in advanced stage (Ⅲ/Ⅳ) were given 96 cycles of combination chemotherapy. Chemotherapy schedules included Taxol+CBP, Gemzar+CBP and NVB+CBE The dose of CBP was at 5 mg.mL^-1·min^-1 of area under the concentration-time curve (AUC). Side effects and quality of life were observed before and after the chemotherapy. Myelosuppression was severe and commonly observed. Grade 3/4 of granulocytopenia was found in 47.9% (46/96) of the patients and grade 3/4 of thrombocytopenia was noted in 28.1% (27/96) of the subjects. However, other side effects were slight. The mean score of quality of life (QOL), according to the criteria of QOL for Chinese cancer patients had reduced 6.8. At 5 mg.mL^-1·min^-1 by AUC, the hematological toxicity of CBP was severe and it had some negative effects on the QOL. The administration of CBP at 5 mg.mL^-1·min^-1 by AUC may be too high for Chinese senile patients with non-small cell lung cancer. 展开更多
关键词 senile patients non-small cell lung cancer carboplatin area under the concentration-time curve quality of life
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ELECTRIC FIRE NEEDLE IN THE TREATMENT OF SENILE IMPOTENCE:A REPORT OF 228 CASES 被引量:1
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作者 Zheng Xueliang Zhang Jiaqi Tiedong Hospital,Anshan Iron and Steel Company,Tiedong,Liaoning Province 114002,ChinaHong Shizhong Singapore Acupuncture and Moxibustion Medical College,Singapore 《World Journal of Acupuncture-Moxibustion》 1993年第2期39-39,共1页
Sexual matters between husband and wifeconcern directly the continuation of the humanrace and harmony of their family.The relationsbetween sexual life and health have been givenspecial attention in traditional medicin... Sexual matters between husband and wifeconcern directly the continuation of the humanrace and harmony of their family.The relationsbetween sexual life and health have been givenspecial attention in traditional medicine.Senileimpotence is a commonly encountered 展开更多
关键词 FIRE CONTINUATION sexual HUSBAND HARMONY seriously senile WARMING suffered transmit
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重症急性胆管炎(ACST)46例诊治体会 被引量:2
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作者 赵晓明 《中国实用医药》 2011年第27期78-79,共2页
目的探讨重症胆管炎(ACST)的诊断和治疗。方法根据对46例ACST患者的病历资料进行分析,总结ACST的诊治经验。结果治愈40例,治愈率86.96%,死亡6例,死亡率13.04%。结论外科医师应充分认识ACST的凶险性,作好围手术期的准备和治疗,选择合理... 目的探讨重症胆管炎(ACST)的诊断和治疗。方法根据对46例ACST患者的病历资料进行分析,总结ACST的诊治经验。结果治愈40例,治愈率86.96%,死亡6例,死亡率13.04%。结论外科医师应充分认识ACST的凶险性,作好围手术期的准备和治疗,选择合理的手术时机、手术方式和有效的治疗方法,以提高患者的治愈率、降低其死亡率。 展开更多
关键词 重症急性胆管炎(acst) 诊治
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Treatment Effects of Acupuncture and Calligraphy Training on Cognitive Abilities in Senile Demented Patients 被引量:1
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作者 Henry S.R.Kao Miqu Wang +6 位作者 Shuguang Yu Shihong Yuan Miranda MY Fung Lin Zhu Stewart P.W.Lam Tin Tin Kao Xiaoyang Kao 《Chinese Medicine and Culture》 2019年第2期95-98,共4页
Purpose:This study compared the relative effectiveness of Chinese calligraphy handwriting(CCH)and acupuncture in the treatment of patients with senile dementia.Materials and Methods:A randomized controlled trial(RCT)w... Purpose:This study compared the relative effectiveness of Chinese calligraphy handwriting(CCH)and acupuncture in the treatment of patients with senile dementia.Materials and Methods:A randomized controlled trial(RCT)with 17 mild-to-moderate dementia patients with an average age of 77.29 years were randomly assigned with 9 to the calligraphy handwriting group and 8 to the acupuncture treatment group for a month of consecutive treatment.The participants'cognitive abilities,as well as symptoms of senile dementia,were measured by the Chinese version of the Mini-mental State Examination(CMMSE)and the Chinese Medicine Quantitative Diagnostic Survey for Senile Dementia Symptoms,respectively,before and after the treatment.Results:The calligraphy group showed a significant increase in calculation and memory as well as a decline in the symptoms of senile dementia.Patients in the acupuncture group experienced a significant growth in total CMMSE scores and the subscales in orientation to time and place,behavioral operations,as well as reduced clinical symptoms.However,no significant changes were found in their memory and calculation abilities.Conclusion:Both CCH and acupuncture treatments were found significantly effective for,respectively,enhancing the patients'cognitive abilities and reducing their clinical symptoms.Further,calligraphy handwriting also improved the level of their attention and concentration,physical relaxation,and emotional stability. 展开更多
关键词 ACUPUNCTURE calligraphy handwriting cognitive abilities senile dementia
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