The association between ambient temperature and acute exacerbation of chronic bronchitis （AECB） was still unknown. Therefore, we performed an epidemiological study in a large hospital of Shanghai to explore the rela...The association between ambient temperature and acute exacerbation of chronic bronchitis （AECB） was still unknown. Therefore, we performed an epidemiological study in a large hospital of Shanghai to explore the relationship about temperature and outpatient visit for AECB. We adopted a quasi-Poisson generalized additive models and distributed lag nonlinear models to estimate the accumulative effects of temperature on AECB across multiple days. We found significant non-linear effects of cold temperature on hospital visits for AECB, and the potential effect of cold temperature might last more than 2 weeks. The relative risks of extreme cold （first percentiles of temperature throughout the study period） and cold （10th percentile of temperature） temperature over lags 0-14 d were 2.98 [95% confidence intervals （CI）： 1.77, 5.04] and 1.63 （95% Ch 1.21, 2.19）, compared with the 25th percentile of temperature. However, we found no positive association between hospital visits and hot weather. This study showed that exposure to both extreme cold and cold temperatures were associated with increased outpatient visits for AECB in a large hospital of Shanghai.展开更多
An international panel of experts discussed recent outcomes from the GIANT Study （Greatest International Antibiotic Trial） which was set up to evaluate the impact on the patients with acute exacerbations of chronic ...An international panel of experts discussed recent outcomes from the GIANT Study （Greatest International Antibiotic Trial） which was set up to evaluate the impact on the patients with acute exacerbations of chronic bronchitis （AECB）, as well as the efficacy and safety of the antibiotic Avelox （Moxifloxacin HCI）.展开更多
基金supported by the National Clinical key subject construction funds(occupational disease program)the National Basic Research Program(973 program)of China(2011CB503802)+3 种基金Gong-Yi Program of China Ministry of Environmental Protection(201209008)China Medical Board Collaborating Program(13-152)Public Welfare Research Program of National HealthFamily Planning Commission of China(201402022)
文摘The association between ambient temperature and acute exacerbation of chronic bronchitis （AECB） was still unknown. Therefore, we performed an epidemiological study in a large hospital of Shanghai to explore the relationship about temperature and outpatient visit for AECB. We adopted a quasi-Poisson generalized additive models and distributed lag nonlinear models to estimate the accumulative effects of temperature on AECB across multiple days. We found significant non-linear effects of cold temperature on hospital visits for AECB, and the potential effect of cold temperature might last more than 2 weeks. The relative risks of extreme cold （first percentiles of temperature throughout the study period） and cold （10th percentile of temperature） temperature over lags 0-14 d were 2.98 [95% confidence intervals （CI）： 1.77, 5.04] and 1.63 （95% Ch 1.21, 2.19）, compared with the 25th percentile of temperature. However, we found no positive association between hospital visits and hot weather. This study showed that exposure to both extreme cold and cold temperatures were associated with increased outpatient visits for AECB in a large hospital of Shanghai.
文摘An international panel of experts discussed recent outcomes from the GIANT Study （Greatest International Antibiotic Trial） which was set up to evaluate the impact on the patients with acute exacerbations of chronic bronchitis （AECB）, as well as the efficacy and safety of the antibiotic Avelox （Moxifloxacin HCI）.
