目的旨在对比Ahemd引流阀(AGV)及Baerveldt引流阀(BGI)治疗青光眼的有效性及安全性。方法计算机检索PubMed,Web of science,Cochrane Library,维普,万方以及中国知网数据库并收集所有与AGV及BGI相关的临床对照试验。有效性评价包括以加...目的旨在对比Ahemd引流阀(AGV)及Baerveldt引流阀(BGI)治疗青光眼的有效性及安全性。方法计算机检索PubMed,Web of science,Cochrane Library,维普,万方以及中国知网数据库并收集所有与AGV及BGI相关的临床对照试验。有效性评价包括以加权平均数(WMD)作为测量指标的眼压下降幅度百分比(IOPR%)及青光眼用药减少百分比,以比值比(OR)作为测量指标的手术完全成功率、条件成功率以及再次青光眼手术发生率。安全性评价为以OR作为测量指标的并发症发生率。结果最终纳入文献5篇,包括811例患者(812眼)。对比AGV,BGI具有更高的IOPR%及青光眼用药减少百分比(WMD=-5.20,95%CI=[-9.55,-0.85],P=0.02;WMD=-14.89,95%CI=[-20.46,-9.32],P<0.001)。另外,BGI的手术完全成功率高于AGV(OR=0.53,95%CI=[-0.31,0.92],P=0.02),而再次青光眼手术发生率则低于AGV(OR=2.49,95%CI=[1.33,4.66],P=0.004)。在手术条件成功率及总并发症发生率方面二者差异并无统计学意义(OR=0.89,95%CI=[0.63,1.24],P=0.48;OR=0.74,95%CI=[0.52,1.04],P=0.09)。结论对比AGV,BGI在降低眼压及减少术后青光眼用药方面更为有效,同时BGI还具有手术成功率高及再次青光眼手术发生率低的特点,而两者在术后并发症发生率方面差异无统计学意义。展开更多
AHEMD-SR(Affordances in the Home Environment for Motor Development-Self Report)was applied to children from 18 to 42 months(N=132),from a coastal municipality of Portugal.The results revealed that the father’s income...AHEMD-SR(Affordances in the Home Environment for Motor Development-Self Report)was applied to children from 18 to 42 months(N=132),from a coastal municipality of Portugal.The results revealed that the father’s income provides more conditions for motor development stimulation,and that a higher number of offspring may result in less conditions for the younger ones.Having a mother,whatever her academic qualifications,is also a factor that promotes better conditions.Thus,in families with fewer resources and more children,it is strategically advisable to technically support the mother.The kindergarten appears to be an equalizer factor for opportunities for access to motor stimulation resources.展开更多
文摘目的旨在对比Ahemd引流阀(AGV)及Baerveldt引流阀(BGI)治疗青光眼的有效性及安全性。方法计算机检索PubMed,Web of science,Cochrane Library,维普,万方以及中国知网数据库并收集所有与AGV及BGI相关的临床对照试验。有效性评价包括以加权平均数(WMD)作为测量指标的眼压下降幅度百分比(IOPR%)及青光眼用药减少百分比,以比值比(OR)作为测量指标的手术完全成功率、条件成功率以及再次青光眼手术发生率。安全性评价为以OR作为测量指标的并发症发生率。结果最终纳入文献5篇,包括811例患者(812眼)。对比AGV,BGI具有更高的IOPR%及青光眼用药减少百分比(WMD=-5.20,95%CI=[-9.55,-0.85],P=0.02;WMD=-14.89,95%CI=[-20.46,-9.32],P<0.001)。另外,BGI的手术完全成功率高于AGV(OR=0.53,95%CI=[-0.31,0.92],P=0.02),而再次青光眼手术发生率则低于AGV(OR=2.49,95%CI=[1.33,4.66],P=0.004)。在手术条件成功率及总并发症发生率方面二者差异并无统计学意义(OR=0.89,95%CI=[0.63,1.24],P=0.48;OR=0.74,95%CI=[0.52,1.04],P=0.09)。结论对比AGV,BGI在降低眼压及减少术后青光眼用药方面更为有效,同时BGI还具有手术成功率高及再次青光眼手术发生率低的特点,而两者在术后并发症发生率方面差异无统计学意义。
基金Funding acknowledgements:This study was partially supported by the Portuguese Foundation for Science and Technology,I.P.under Grant number UIDP/04748/2020。
文摘AHEMD-SR(Affordances in the Home Environment for Motor Development-Self Report)was applied to children from 18 to 42 months(N=132),from a coastal municipality of Portugal.The results revealed that the father’s income provides more conditions for motor development stimulation,and that a higher number of offspring may result in less conditions for the younger ones.Having a mother,whatever her academic qualifications,is also a factor that promotes better conditions.Thus,in families with fewer resources and more children,it is strategically advisable to technically support the mother.The kindergarten appears to be an equalizer factor for opportunities for access to motor stimulation resources.
