This paper considers the problem of the HIV/AIDS Infection Process filtering characterized by three compounds, namely, the number of healthy T-cells, the number of infected T-cells and free virus particles. Only the f...This paper considers the problem of the HIV/AIDS Infection Process filtering characterized by three compounds, namely, the number of healthy T-cells, the number of infected T-cells and free virus particles. Only the first and third of them can be measurable during the medical treatment process. Moreover, the exact parameter values are admitted to be also unknown. So, here we deal with an uncertain dynamic model that excludes the application of classical filtering theory and requires the application of robust filters successfully working in the absence of a complete mathematical model of the considered process. The problem is to estimate the number of infected T-cells based on the available information. Here we admit the presence of stochastic “white noise” in current observations. To do that we apply the Luenberger-like filter (software sensor) with a matrix gain, which should be adjusted at the beginning of the process in such a way that the filtering error would be as less as possible using the Attractive Ellipsoid Method (AEM). It is shown that the corresponding trajectories of the filtering error converge to an ellipsoidal set of a prespecified form in mean-square sense. To generate the experimental data sequences in the test-simulation example, we have used the well-known simplified HIV/ AIDS model. The obtained results confirm the effectiveness of the suggested approach.展开更多
This paper shows how mathematical methods can be implemented to formulate guidelines for clinical testing and monitoring of HIV/AIDS disease. First, a mathematical model for HIV infection is presented which the measur...This paper shows how mathematical methods can be implemented to formulate guidelines for clinical testing and monitoring of HIV/AIDS disease. First, a mathematical model for HIV infection is presented which the measurement of the CD4+T cells and the viral load counts are needed to estimate all its parameters. Next, through an analysis of model properties, the minimal number of measurement samples is obtained. In the sequel, the effect of Reverse Transcriptase enzyme Inhibitor (RTI) on HIV progression is demonstrated by using a control function. Also the total cost of treatment by this kind of drugs has been minimized. The numerical results are obtained by a numerical method in discretization issue, called AVK.展开更多
The object matching and distribution problem is a traditional challenge in different kinds of networks, such as kidney distribution networks. Applying differential element analysis methods, decision tree, integer line...The object matching and distribution problem is a traditional challenge in different kinds of networks, such as kidney distribution networks. Applying differential element analysis methods, decision tree, integer linear programming the-ory and stochastic processes ideas, we propose models for the objects matching, the distribu-tion network, the exchange system and the in-dividual decision-making strategy, and thor-oughly analyze the relationship between the matching rate and the waiting time, and their impacts on the efficiency of the donor-matching process. And as the experiments, we evaluate the algorithms and system by kidney matching, decision making and distribution problems on real world data.展开更多
This paper presents a general method for 2D/3D transformation, which can be efficiently used in three dimensional computer aided garment design. The method utilizes a uniform triangular spring_mass based deformable mo...This paper presents a general method for 2D/3D transformation, which can be efficiently used in three dimensional computer aided garment design. The method utilizes a uniform triangular spring_mass based deformable model. 2D to 3D transformation and 3D to 2D transformation both can be implemented on the same model. A general and efficient collision detection method is also briefly discussed in this paper.展开更多
目的探究医生对人工智能辅助诊疗系统(aided diagnosis and treatment system,ADTS)的采纳意愿及其影响因素,厘清ADTS推行的重要环节,进而提出优化技术、管理的建议。方法在整合型技术接受使用模型的基础上添加感知风险、认知信任、法...目的探究医生对人工智能辅助诊疗系统(aided diagnosis and treatment system,ADTS)的采纳意愿及其影响因素,厘清ADTS推行的重要环节,进而提出优化技术、管理的建议。方法在整合型技术接受使用模型的基础上添加感知风险、认知信任、法律监管等因素设计问卷,在预调研修正后对226份正式回收问卷数据进行信度和效度分析、假设检验、结构方程模型拟合,得到医生ADTS采纳意愿关系链模型。结果绩效期望、认知信任、社会影响对医生的行为意愿产生直接正向影响,其中社会影响的作用效果最大;促成因素、法律监管等存在间接影响。研究还发现,使用过ADTS的医生在绩效期望、努力期望、学习适应性等多方面赋分较高。结论落实ADTS应用应重视培训科普、建立运维体系、完善风险责任规制,需要多方合力。展开更多
文摘This paper considers the problem of the HIV/AIDS Infection Process filtering characterized by three compounds, namely, the number of healthy T-cells, the number of infected T-cells and free virus particles. Only the first and third of them can be measurable during the medical treatment process. Moreover, the exact parameter values are admitted to be also unknown. So, here we deal with an uncertain dynamic model that excludes the application of classical filtering theory and requires the application of robust filters successfully working in the absence of a complete mathematical model of the considered process. The problem is to estimate the number of infected T-cells based on the available information. Here we admit the presence of stochastic “white noise” in current observations. To do that we apply the Luenberger-like filter (software sensor) with a matrix gain, which should be adjusted at the beginning of the process in such a way that the filtering error would be as less as possible using the Attractive Ellipsoid Method (AEM). It is shown that the corresponding trajectories of the filtering error converge to an ellipsoidal set of a prespecified form in mean-square sense. To generate the experimental data sequences in the test-simulation example, we have used the well-known simplified HIV/ AIDS model. The obtained results confirm the effectiveness of the suggested approach.
文摘This paper shows how mathematical methods can be implemented to formulate guidelines for clinical testing and monitoring of HIV/AIDS disease. First, a mathematical model for HIV infection is presented which the measurement of the CD4+T cells and the viral load counts are needed to estimate all its parameters. Next, through an analysis of model properties, the minimal number of measurement samples is obtained. In the sequel, the effect of Reverse Transcriptase enzyme Inhibitor (RTI) on HIV progression is demonstrated by using a control function. Also the total cost of treatment by this kind of drugs has been minimized. The numerical results are obtained by a numerical method in discretization issue, called AVK.
文摘The object matching and distribution problem is a traditional challenge in different kinds of networks, such as kidney distribution networks. Applying differential element analysis methods, decision tree, integer linear programming the-ory and stochastic processes ideas, we propose models for the objects matching, the distribu-tion network, the exchange system and the in-dividual decision-making strategy, and thor-oughly analyze the relationship between the matching rate and the waiting time, and their impacts on the efficiency of the donor-matching process. And as the experiments, we evaluate the algorithms and system by kidney matching, decision making and distribution problems on real world data.
文摘This paper presents a general method for 2D/3D transformation, which can be efficiently used in three dimensional computer aided garment design. The method utilizes a uniform triangular spring_mass based deformable model. 2D to 3D transformation and 3D to 2D transformation both can be implemented on the same model. A general and efficient collision detection method is also briefly discussed in this paper.
文摘目的探究医生对人工智能辅助诊疗系统(aided diagnosis and treatment system,ADTS)的采纳意愿及其影响因素,厘清ADTS推行的重要环节,进而提出优化技术、管理的建议。方法在整合型技术接受使用模型的基础上添加感知风险、认知信任、法律监管等因素设计问卷,在预调研修正后对226份正式回收问卷数据进行信度和效度分析、假设检验、结构方程模型拟合,得到医生ADTS采纳意愿关系链模型。结果绩效期望、认知信任、社会影响对医生的行为意愿产生直接正向影响,其中社会影响的作用效果最大;促成因素、法律监管等存在间接影响。研究还发现,使用过ADTS的医生在绩效期望、努力期望、学习适应性等多方面赋分较高。结论落实ADTS应用应重视培训科普、建立运维体系、完善风险责任规制,需要多方合力。
