N labeled alamethicin dimer was synthesized. The structure and dynamics of alamethicin dimers were studied with nuclear magnetic resonance (NMR) spectroscopy. The data from 15 N-labeled alamethicin dimer suggest l...N labeled alamethicin dimer was synthesized. The structure and dynamics of alamethicin dimers were studied with nuclear magnetic resonance (NMR) spectroscopy. The data from 15 N-labeled alamethicin dimer suggest little differences in conformation between the dimer and monomer in the Aib 1 -Pro 14 region. Significant difference in the conformation of the C-terminus are manifest in the NH chemical shifts in the Val 15 -Pho 20 region.展开更多
文摘N labeled alamethicin dimer was synthesized. The structure and dynamics of alamethicin dimers were studied with nuclear magnetic resonance (NMR) spectroscopy. The data from 15 N-labeled alamethicin dimer suggest little differences in conformation between the dimer and monomer in the Aib 1 -Pro 14 region. Significant difference in the conformation of the C-terminus are manifest in the NH chemical shifts in the Val 15 -Pho 20 region.
