A novel scheme of all-optical AND gate based on a Fabry-Perot semiconductor optical amplifier(FP-SOA) is proposed and its feasibility is verified by simulation. Using this scheme, all-optical AND gate can be realized ...A novel scheme of all-optical AND gate based on a Fabry-Perot semiconductor optical amplifier(FP-SOA) is proposed and its feasibility is verified by simulation. Using this scheme, all-optical AND gate can be realized with the extinction ratio of 10 dB. The influence of pulse interval and pulse width on the extinction ratio is also investigated.展开更多
Cold spare is the most common configuration amongst the three types of configuration for systems used on board and for power generation systems. A new approach to calculate the unavailability of systems composed of id...Cold spare is the most common configuration amongst the three types of configuration for systems used on board and for power generation systems. A new approach to calculate the unavailability of systems composed of identical spares in cold spare configuration was proposed in this study. Instead of using the spare gate of dynamic fault tree( DFT) and the Markov analysis,AND gate of static fault tree used for calculating the unavailability of cold spare systems was proposed in this paper. By using this approach,unavailability of identical cold spare systems composed of nonrepairable spare components can be calculated exactly and systems composed of both repairable and nonreparable identical spare components can be estimated without building large Markov state diagram.展开更多
In this paper, analysis of DC and analog/RF performance on cylindrical gate-all-around tunnel fieldeffect transistor（TFET） has been made using distinct device geometry. Firstly, performance parameters of GAATFET are...In this paper, analysis of DC and analog/RF performance on cylindrical gate-all-around tunnel fieldeffect transistor（TFET） has been made using distinct device geometry. Firstly, performance parameters of GAATFET are analyzed in terms of drain current, gate capacitances, transconductance, source-drain conductance at different radii and channel length. Furthermore, we also produce the geometrical analysis towards the optimized investigation of radio frequency parameters like cut-off frequency, maximum oscillation frequency and gain bandwidth product using a 3D technology computer-aided design ATLAS. Due to band-to-band tunneling based current mechanism unlike MOSFET, gate-bias dependence values as primary parameters of TFET differ. We also analyze that the maximum current occurs when radii of Si is around 8 nm due to high gate controllability over channel with reduced fringing effects and also there is no change in the current of TFET on varying its length from 100 to 40 nm.However current starts to increase when channel length is further reduced for 40 to 30 nm. Both of these trades-offs affect the RF performance of the device.展开更多
Framework nucleic acids(FNAs)have emerged as intelligent sensing systems for the detection of tumor-related biomarkers in living cells.However,orthogonally controlled manipulation of FNAs-based nanodevices for on-site...Framework nucleic acids(FNAs)have emerged as intelligent sensing systems for the detection of tumor-related biomarkers in living cells.However,orthogonally controlled manipulation of FNAs-based nanodevices for on-site imaging of microRNAs(miRNAs)remains an intractable challenge.Herein,we report a dual endogenous stimuli-responsive FNA nanodevice that can perform miRNA sensing and imaging in a tumor-specificmanner.The sensing function of the nanodevice is silent(OFF)by rationally incorporating adenosine 5′-triphosphate(ATP)aptamer and an abasic site,which can also be activated(ON)with ATP and human apurinic/apyrimidinic endonuclease 1(APE1)in tumor cells,enabling on-site and efficient miRNA imaging with improved tumor specificity.Furthermore,we demonstrate the capability of the nanodevice for specificmiRNAimagingboth in living cells and in vivo based on the“dual keys”(overexpressed ATP and APE1 in tumors)priming mode.Therefore,this work illustrates a simple biosensing methodology with great potential for precise imaging of tumor biomarkers in clinical diagnosis and therapeutic evaluation.展开更多
基金National Nature Science Foundation of China(60572008)
文摘A novel scheme of all-optical AND gate based on a Fabry-Perot semiconductor optical amplifier(FP-SOA) is proposed and its feasibility is verified by simulation. Using this scheme, all-optical AND gate can be realized with the extinction ratio of 10 dB. The influence of pulse interval and pulse width on the extinction ratio is also investigated.
基金National High-Technology Research and Development Program of China(863 Program)(No.2013AA040203)
文摘Cold spare is the most common configuration amongst the three types of configuration for systems used on board and for power generation systems. A new approach to calculate the unavailability of systems composed of identical spares in cold spare configuration was proposed in this study. Instead of using the spare gate of dynamic fault tree( DFT) and the Markov analysis,AND gate of static fault tree used for calculating the unavailability of cold spare systems was proposed in this paper. By using this approach,unavailability of identical cold spare systems composed of nonrepairable spare components can be calculated exactly and systems composed of both repairable and nonreparable identical spare components can be estimated without building large Markov state diagram.
基金supported by the Council of Scientific and Industrial Research(CSIR)Funded Research Project,Grant No.22/0651/14/EMR-II,Government of India
文摘In this paper, analysis of DC and analog/RF performance on cylindrical gate-all-around tunnel fieldeffect transistor（TFET） has been made using distinct device geometry. Firstly, performance parameters of GAATFET are analyzed in terms of drain current, gate capacitances, transconductance, source-drain conductance at different radii and channel length. Furthermore, we also produce the geometrical analysis towards the optimized investigation of radio frequency parameters like cut-off frequency, maximum oscillation frequency and gain bandwidth product using a 3D technology computer-aided design ATLAS. Due to band-to-band tunneling based current mechanism unlike MOSFET, gate-bias dependence values as primary parameters of TFET differ. We also analyze that the maximum current occurs when radii of Si is around 8 nm due to high gate controllability over channel with reduced fringing effects and also there is no change in the current of TFET on varying its length from 100 to 40 nm.However current starts to increase when channel length is further reduced for 40 to 30 nm. Both of these trades-offs affect the RF performance of the device.
基金supported by the Natural Science Foundation of China(grant nos.21877030,21735002,and 21778016).
文摘Framework nucleic acids(FNAs)have emerged as intelligent sensing systems for the detection of tumor-related biomarkers in living cells.However,orthogonally controlled manipulation of FNAs-based nanodevices for on-site imaging of microRNAs(miRNAs)remains an intractable challenge.Herein,we report a dual endogenous stimuli-responsive FNA nanodevice that can perform miRNA sensing and imaging in a tumor-specificmanner.The sensing function of the nanodevice is silent(OFF)by rationally incorporating adenosine 5′-triphosphate(ATP)aptamer and an abasic site,which can also be activated(ON)with ATP and human apurinic/apyrimidinic endonuclease 1(APE1)in tumor cells,enabling on-site and efficient miRNA imaging with improved tumor specificity.Furthermore,we demonstrate the capability of the nanodevice for specificmiRNAimagingboth in living cells and in vivo based on the“dual keys”(overexpressed ATP and APE1 in tumors)priming mode.Therefore,this work illustrates a simple biosensing methodology with great potential for precise imaging of tumor biomarkers in clinical diagnosis and therapeutic evaluation.
