A series of 2,3-dihydroquinazolin-4（1H）-ones have been synthesized in good to excellent yields through direct cyclocondensation of anthranilamide and aryl aldehydes or ketones in water or methanol under mild conditi...A series of 2,3-dihydroquinazolin-4（1H）-ones have been synthesized in good to excellent yields through direct cyclocondensation of anthranilamide and aryl aldehydes or ketones in water or methanol under mild conditions.The reaction was efficiently promoted by 10 mol%sulfamic acid（SA,H_2NSO_3H） and the catalyst could be recovered easily after the reactions and reused without evident loss of reactivity.展开更多
A simple and facile method for the synthesis of 2,3-dihydroquinazolin-4（1H）-ones through the direct cyclocon- densation of one-pot three-component cyclocondensation of isatoic anhydride, ammonium acetate （or primar...A simple and facile method for the synthesis of 2,3-dihydroquinazolin-4（1H）-ones through the direct cyclocon- densation of one-pot three-component cyclocondensation of isatoic anhydride, ammonium acetate （or primary amines） and aldehydes; and anthranilamide and aldehydes using silica supported ferric chloride （SiO2-FeCl3） as catalyst under solvent-free conditions is described.展开更多
文摘A series of 2,3-dihydroquinazolin-4（1H）-ones have been synthesized in good to excellent yields through direct cyclocondensation of anthranilamide and aryl aldehydes or ketones in water or methanol under mild conditions.The reaction was efficiently promoted by 10 mol%sulfamic acid（SA,H_2NSO_3H） and the catalyst could be recovered easily after the reactions and reused without evident loss of reactivity.
文摘A simple and facile method for the synthesis of 2,3-dihydroquinazolin-4（1H）-ones through the direct cyclocon- densation of one-pot three-component cyclocondensation of isatoic anhydride, ammonium acetate （or primary amines） and aldehydes; and anthranilamide and aldehydes using silica supported ferric chloride （SiO2-FeCl3） as catalyst under solvent-free conditions is described.
