云时代,云API作为服务交付、数据交换和能力复制的最佳载体,已成长为当今面向服务软件开发和企业数字化转型不可或缺的核心要素.然而动态开放网络中持续增长的云API在给开发者提供了更多选择的同时,也将其淹没在海量的云API选择之中,设...云时代,云API作为服务交付、数据交换和能力复制的最佳载体,已成长为当今面向服务软件开发和企业数字化转型不可或缺的核心要素.然而动态开放网络中持续增长的云API在给开发者提供了更多选择的同时,也将其淹没在海量的云API选择之中,设计有效的云API推荐方法就此成为API经济健康发展中迫切要解决的现实问题.但是,现有研究主要利用搜索关键词、服务质量和调用偏好进行建模,生成质量高功能单一的云API推荐列表,没有考虑服务化软件实际开发中开发者对多元化高阶互补云API的客观需要.高阶互补云API推荐旨在为多个查询云API生成多元互补云API列表,要求推荐结果与查询云API均互补,以满足开发者的联合需求.针对此问题,本文提出基于概率逻辑推理的高阶互补云API推荐方法(Probabilistic Logic Reasoning for High-order Complementary Cloud API Recom⁃mendation,PLR4HCCR).首先,通过云API生态真实数据分析论证云API互补推荐需求的必要性和互补关系建模中替补噪声的客观存在,为云API互补推荐问题研究提供动机和数据支持.其次,采用Beta概率嵌入对云API及其之间的关系约束进行编码,以刻画云API间互补关系的不确定性和支持互补逻辑推理.接着,设计由投影、取反和交并三个基本逻辑算子构建的互补关系逻辑推理网络,使查询集中的每个云API获得非对称互补关系感知和替补噪声消解约束下的互补云API表示.然后,引入注意力机制为查询云API的互补云API分配不同权重,增强高阶互补云API基向量的表征能力.在此基础上,采用KL散度度量高阶互补云API基向量与候选云API之间的距离,并根据KL散度排序生成高阶互补性可感知下的云API推荐结果.最后,我们利用两个真实云API数据集在不同阶互补推荐场景下进行实验,实验表明,与传统启发式推荐方法和深度学习推荐方法相比,PLR4HCCR在互补关系感知推理和替补噪声消解方面均具有较大的优势,继而使其在低阶、高阶和混合阶互补云API推荐中均展示出更优的推荐效果和更强的泛化能力.进一步,超参数敏感性实验、实例分析和用户调查验证了方法的有效性、实用性和可行性,这使结合高阶互补关系的云API推荐方法PLR4HCCR不仅更有可能生成开发者满意的结果,而且可有效提升云API服务提供者的收益.展开更多
加密型勒索软件通过加密用户文件来勒索赎金.现有的基于第一条加密应用编程接口(Application Programming Interface,API)的早期检测方法无法在勒索软件执行加密行为前将其检出.由于不同家族的勒索软件开始执行其加密行为的时刻各不相同...加密型勒索软件通过加密用户文件来勒索赎金.现有的基于第一条加密应用编程接口(Application Programming Interface,API)的早期检测方法无法在勒索软件执行加密行为前将其检出.由于不同家族的勒索软件开始执行其加密行为的时刻各不相同,现有的基于固定时间阈值的早期检测方法仅能将少量勒索软件在其执行加密行为前准确检出.为进一步提升勒索软件检测的及时性,本文在分析多款勒索软件运行初期调用动态链接库(Dynamic Link Library,DLL)和API行为的基础上,提出了一个表征软件从开始运行到首次调用加密相关DLL之间的时间段的概念——运行初始阶段(Initial Phase of Operation,IPO),并提出了一个以软件在IPO内产生的API序列为检测对象的勒索软件早期检测方法,即基于API潜在语义的勒索软件早期检测方法(Ransomware Early Detection Method based on API Latent Semantics,REDMALS).REDMALS采集IPO内的API序列后,采用TF-IDF(Term Frequency-Inverse Document Frequency)算法以及潜在语义分析(Latent Semantic Analysis,LSA)算法对采集的API序列生成特征向量及提取潜在的语义结构,再运用机器学习算法构建检测模型用于勒索软件检测.实验结果显示运用随机森林算法的REDMALS在构建的变种测试集和未知测试集上可分别获得97.7%、96.0%的准确率,且两个测试集中83%和76%的勒索软件样本可在其执行加密行为前被检出.展开更多
The use of robots to augment human capabilities and assist in work has long been an aspiration.Robotics has been developing since the 1960s when the first industrial robot was introduced.As technology has advanced,rob...The use of robots to augment human capabilities and assist in work has long been an aspiration.Robotics has been developing since the 1960s when the first industrial robot was introduced.As technology has advanced,robotic-assisted surgery has shown numerous advantages,including more precision,efficiency,minimal invasiveness,and safety than is possible with conventional techniques,which are research hotspots and cutting-edge trends.This article reviewed the history of medical robot development and seminal research papers about current research progress.Taking the autonomous dental implant robotic system as an example,the advantages and prospects of medical robotic systems would be discussed which would provide a reference for future research.展开更多
Nowadays,the rapid development of the social economy inevitably leads to global energy and environmental crisis.For this reason,more and more scholars focus on the development of photocatalysis and/or electrocatalysis...Nowadays,the rapid development of the social economy inevitably leads to global energy and environmental crisis.For this reason,more and more scholars focus on the development of photocatalysis and/or electrocatalysis technology for the advantage in the sustainable production of high-value-added products,and the high efficiency in pollutants remediation.Although there is plenty of outstanding research has been put forward continuously,most of them focuses on catalysis performance and reaction mechanisms in laboratory conditions.Realizing industrial application of photo/electrocatalytic processes is still a challenge that needs to be overcome by social demand.In this regard,this review comprehensively summarized several explorations in thefield of photo/electrocatalytic reduction towards potential industrial applications in recent years.Special attention is paid to the successful attempts and the current status of photo/electrocatalytic water splitting,carbon dioxide conversion,resource utilization from waste,etc.,by using advanced reactors.The key problems and challenges of photo/electrocatalysis in future industrial practice are also discussed,and the possible development directions are also pointed out from the industry view.展开更多
The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(R...The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(RCZ) is built. The formula for an ultimate cutting force is established based on the limit equilibrium principle. The relationship between digital drilling parameters(DDP) and the c-φ parameter(DDP-cφ formula, where c refers to the cohesion and φ refers to the internal friction angle) is derived, and the response of drilling parameters and cutting ratio to the strength parameters is analyzed. The drillingbased measuring method for the c-φ parameter of rock is constructed. The laboratory verification test is then completed, and the difference in results between the drilling test and the compression test is less than 6%. On this basis, in-situ rock drilling tests in a traffic tunnel and a coal mine roadway are carried out, and the strength parameters of the surrounding rock are effectively tested. The average difference ratio of the results is less than 11%, which verifies the effectiveness of the proposed method for obtaining the strength parameters based on digital drilling. This study provides methodological support for field testing of rock strength parameters.展开更多
针对目前恶意软件检测分类方法在特征提取、检测准确率等方面面临的挑战,提出一种基于API分组重构与图像表示的恶意软件检测分类方法。首先,对恶意软件调用的API类别统一编号,将API指令序列中相同编号的API聚合为同一API组,根据恶意软...针对目前恶意软件检测分类方法在特征提取、检测准确率等方面面临的挑战,提出一种基于API分组重构与图像表示的恶意软件检测分类方法。首先,对恶意软件调用的API类别统一编号,将API指令序列中相同编号的API聚合为同一API组,根据恶意软件运行时各类API的首次调用顺序对API组重排序,将各API组的条目数记录为该类API对软件样本的贡献度。经分组重构后,各API组按序组织,其顺序为软件样本调用各类API的顺序。各API组内部有序,其内部各API的排列顺序即为软件样本对单个API的调用顺序。有序化的API分组有助于API指令序列信息的图像化表达。基于重组的API指令序列提取API编号作为全局特征列表、API贡献度作为局部特征列表、API顺序索引作为时序特征列表,对特征列表进行标准化与零填充,转化为统一尺寸的特征数组。其中,API编号能清晰地标识API类别,API贡献度可以表征该API的调用频繁程度,API顺序索引可区分各API被调用的顺序。然后,分别用3类特征数组填充RGB图像的3个通道,生成3通道的API编号贡献度及顺序索引特征图像(Feature image of API code devotion and sequential index,FimgCDS)。最后,将Fimg CDS特征图像输入自主构建的轻量型恶意软件特征图像卷积神经网络(malware feature image convolutional neural network,MficNN)分类器,实现对恶意软件的检测与分类。实验结果表明,本文方法在两类数据集上的检测分类准确率分别为98.66%和98.35%,具有较高的恶意软件检测分类性能指标和检测分类速度。展开更多
Flexible sensors based on MXene-polymer composites are highly prospective for next-generation wearable electronics used in human-machine interfaces.One of the motivating factors behind the progress of flexible sensors...Flexible sensors based on MXene-polymer composites are highly prospective for next-generation wearable electronics used in human-machine interfaces.One of the motivating factors behind the progress of flexible sensors is the steady arrival of new conductive materials.MXenes,a new family of 2D nanomaterials,have been draw-ing attention since the last decade due to their high electronic conduc-tivity,processability,mechanical robustness and chemical tunability.In this review,we encompass the fabrication of MXene-based polymeric nanocomposites,their structure-property relationship,and applications in the flexible sensor domain.Moreover,our discussion is not only lim-ited to sensor design,their mechanism,and various modes of sensing platform,but also their future perspective and market throughout the world.With our article,we intend to fortify the bond between flexible matrices and MXenes thus promoting the swift advancement of flexible MXene-sensors for wearable technologies.展开更多
Background: Bilayer artificial dermis promotes wound healing and offers a treatment option for chronic wounds. Aim: Examine the clinical efficacy of bilayer artificial dermis combined with Vacuum Sealing Drainage (VSD...Background: Bilayer artificial dermis promotes wound healing and offers a treatment option for chronic wounds. Aim: Examine the clinical efficacy of bilayer artificial dermis combined with Vacuum Sealing Drainage (VSD) technology in the treatment of chronic wounds. Method: From June 2021 to December 2023, our hospital treated 24 patients with chronic skin tissue wounds on their limbs using a novel tissue engineering product, the bilayer artificial dermis, in combination with VSD technology to repair the wounds. The bilayer artificial dermis protects subcutaneous tissue, blood vessels, nerves, muscles, and tendons, and also promotes the growth of granulation tissue and blood vessels to aid in wound healing when used in conjunction with VSD technology for wound dressing changes in chronic wounds. Results: In this study, 24 cases of chronic wounds with exposed bone or tendon larger than 1.0 cm2 were treated with a bilayer artificial skin combined with VSD dressing after wound debridement. The wounds were not suitable for immediate skin grafting. At 2 - 3 weeks post-treatment, good granulation tissue growth was observed. Subsequent procedures included thick skin grafting or wound dressing changes until complete wound healing. Patients were followed up on average for 3 months (range: 1 - 12 months) post-surgery. Comparative analysis of the appearance, function, skin color, elasticity, and sensation of the healed chronic wounds revealed superior outcomes compared to traditional skin fl repairs, resulting in significantly higher satisfaction levels among patients and their families. Conclusion: The application of bilayer artificial dermis combined with VSD technology for the repair of chronic wounds proves to be a viable method, yielding satisfactory therapeutic effects compared to traditional skin flap procedures.展开更多
The purpose of this study was to investigate the clinical application of severe acute respiratory distress syndrome coronavirus-2(SARS-CoV-2)specific antibody detection and anti-SARS-CoV-2 specific monoclonal antibodi...The purpose of this study was to investigate the clinical application of severe acute respiratory distress syndrome coronavirus-2(SARS-CoV-2)specific antibody detection and anti-SARS-CoV-2 specific monoclonal antibodies(mAbs)in the treatment of coronavirus infectious disease 2019(COVID-19).The dynamic changes of SARS-CoV-2 specific antibodies during COVID-19 were studied.Immunoglobulin M(IgM)appeared earlier and lasted for a short time,while immunoglobulin G(IgG)appeared later and lasted longer.IgM tests can be used for early diagnosis of COVID-19,and IgG tests can be used for late diagnosis of COVID-19 and identification of asymptomatic infected persons.The combination of antibody testing and nucleic acid testing,which complement each other,can improve the diagnosis rate of COVID-19.Monoclonal anti-SARS-CoV-2 specific antibodies can be used to treat hospitalized severe and critically ill patients and non-hospitalized mild to moderate COVID-19 patients.COVID-19 convalescent plasma,highly concentrated immunoglobulin,and anti-SARS-CoV-2 specific mAbs are examples of anti-SARS-CoV-2 antibody products.Due to the continuous emergence of mutated strains of the novel coronavirus,especially omicron,its immune escape ability and infectivity are enhanced,making the effects of authorized products reduced or invalid.Therefore,the optimal application of anti-SARS-CoV-2 antibody products(especially anti-SARS-CoV-2 specific mAbs)is more effective in the treatment of COVID-19 and more conducive to patient recovery.展开更多
Improved radio-frequency(RF)power performance of InAlN/GaN high electron mobility transistor(HEMT)is achieved by optimizing the rapid thermal annealing(RTA)process for high-performance low-voltage terminal application...Improved radio-frequency(RF)power performance of InAlN/GaN high electron mobility transistor(HEMT)is achieved by optimizing the rapid thermal annealing(RTA)process for high-performance low-voltage terminal applications.By optimizing the RTA temperature and time,the optimal annealing condition is found to enable low parasitic resistance and thus a high-performance device.Besides,compared with the non-optimized RTA HEMT,the optimized one demonstrates smoother ohmic metal surface morphology and better heterojunction quality including the less degraded heterojunction sheet resistance and clearer heterojunction interfaces as well as negligible material out-diffusion from the barrier to the channel and buffer.Benefiting from the lowered parasitic resistance,improved maximum output current density of 2279 mA·mm^(-1)and higher peak extrinsic transconductance of 526 mS·mm^(-1)are obtained for the optimized RTA HEMT.In addition,due to the superior heterojunction quality,the optimized HEMT shows reduced off-state leakage current of 7×10^(-3)mA·mm^(-1)and suppressed current collapse of only 4%,compared with those of 1×10^(-1)mA·mm^(-1)and 15%for the non-optimized one.At 8 GHz and V_(DS)of 6 V,a significantly improved power-added efficiency of 62%and output power density of 0.71 W·mm^(-1)are achieved for the optimized HEMT,as the result of the improvement in output current,knee voltage,off-state leakage current,and current collapse,which reveals the tremendous advantage of the optimized RTA HEMT in high-performance low-voltage terminal applications.展开更多
An analytic hierarchy process(AHP)was employed to assess the applicability of 18 new and superior varieties of flowers in Hefei City flower border applications.A total of 12 indicators were selected from three distinc...An analytic hierarchy process(AHP)was employed to assess the applicability of 18 new and superior varieties of flowers in Hefei City flower border applications.A total of 12 indicators were selected from three distinct aspects of adaptability,ornamental characteristics and use traits,in order to establish a comprehensive evaluation model.The results demonstrate that grade I(J≥2.685)exhibits excellent application value,encompassing six species of plants,such asHydrangeamacrophylla‘Endless Summer’;grade II(2.684≤J≤2.420)is also of notable application value,encompassing five species of plants,such asCallistemonrigidus;grade III(2.419≤J≤2.615)is of average application value,including five species of plants,such asCrocosmiacrocosmiflora;grade IV(J≤2.16)is of relatively poor application value.The evaluation results may be utilized as a theoretical reference for the promotion of new and superior varieties in the flower border of Hefei.展开更多
文摘云时代,云API作为服务交付、数据交换和能力复制的最佳载体,已成长为当今面向服务软件开发和企业数字化转型不可或缺的核心要素.然而动态开放网络中持续增长的云API在给开发者提供了更多选择的同时,也将其淹没在海量的云API选择之中,设计有效的云API推荐方法就此成为API经济健康发展中迫切要解决的现实问题.但是,现有研究主要利用搜索关键词、服务质量和调用偏好进行建模,生成质量高功能单一的云API推荐列表,没有考虑服务化软件实际开发中开发者对多元化高阶互补云API的客观需要.高阶互补云API推荐旨在为多个查询云API生成多元互补云API列表,要求推荐结果与查询云API均互补,以满足开发者的联合需求.针对此问题,本文提出基于概率逻辑推理的高阶互补云API推荐方法(Probabilistic Logic Reasoning for High-order Complementary Cloud API Recom⁃mendation,PLR4HCCR).首先,通过云API生态真实数据分析论证云API互补推荐需求的必要性和互补关系建模中替补噪声的客观存在,为云API互补推荐问题研究提供动机和数据支持.其次,采用Beta概率嵌入对云API及其之间的关系约束进行编码,以刻画云API间互补关系的不确定性和支持互补逻辑推理.接着,设计由投影、取反和交并三个基本逻辑算子构建的互补关系逻辑推理网络,使查询集中的每个云API获得非对称互补关系感知和替补噪声消解约束下的互补云API表示.然后,引入注意力机制为查询云API的互补云API分配不同权重,增强高阶互补云API基向量的表征能力.在此基础上,采用KL散度度量高阶互补云API基向量与候选云API之间的距离,并根据KL散度排序生成高阶互补性可感知下的云API推荐结果.最后,我们利用两个真实云API数据集在不同阶互补推荐场景下进行实验,实验表明,与传统启发式推荐方法和深度学习推荐方法相比,PLR4HCCR在互补关系感知推理和替补噪声消解方面均具有较大的优势,继而使其在低阶、高阶和混合阶互补云API推荐中均展示出更优的推荐效果和更强的泛化能力.进一步,超参数敏感性实验、实例分析和用户调查验证了方法的有效性、实用性和可行性,这使结合高阶互补关系的云API推荐方法PLR4HCCR不仅更有可能生成开发者满意的结果,而且可有效提升云API服务提供者的收益.
文摘加密型勒索软件通过加密用户文件来勒索赎金.现有的基于第一条加密应用编程接口(Application Programming Interface,API)的早期检测方法无法在勒索软件执行加密行为前将其检出.由于不同家族的勒索软件开始执行其加密行为的时刻各不相同,现有的基于固定时间阈值的早期检测方法仅能将少量勒索软件在其执行加密行为前准确检出.为进一步提升勒索软件检测的及时性,本文在分析多款勒索软件运行初期调用动态链接库(Dynamic Link Library,DLL)和API行为的基础上,提出了一个表征软件从开始运行到首次调用加密相关DLL之间的时间段的概念——运行初始阶段(Initial Phase of Operation,IPO),并提出了一个以软件在IPO内产生的API序列为检测对象的勒索软件早期检测方法,即基于API潜在语义的勒索软件早期检测方法(Ransomware Early Detection Method based on API Latent Semantics,REDMALS).REDMALS采集IPO内的API序列后,采用TF-IDF(Term Frequency-Inverse Document Frequency)算法以及潜在语义分析(Latent Semantic Analysis,LSA)算法对采集的API序列生成特征向量及提取潜在的语义结构,再运用机器学习算法构建检测模型用于勒索软件检测.实验结果显示运用随机森林算法的REDMALS在构建的变种测试集和未知测试集上可分别获得97.7%、96.0%的准确率,且两个测试集中83%和76%的勒索软件样本可在其执行加密行为前被检出.
基金supported by the National Natural Science Foundation of China[grant number 81970987].
文摘The use of robots to augment human capabilities and assist in work has long been an aspiration.Robotics has been developing since the 1960s when the first industrial robot was introduced.As technology has advanced,robotic-assisted surgery has shown numerous advantages,including more precision,efficiency,minimal invasiveness,and safety than is possible with conventional techniques,which are research hotspots and cutting-edge trends.This article reviewed the history of medical robot development and seminal research papers about current research progress.Taking the autonomous dental implant robotic system as an example,the advantages and prospects of medical robotic systems would be discussed which would provide a reference for future research.
基金supported by the National Natural Science Foundation of China(22278030,22090032,22090030,22288102,22242019)the Fundamental Research Funds for the Central Universities(buctrc202119,2312018RC07)+1 种基金Major Program of Qingyuan Innovation Laboratory(Grant No.001220005)the Experiments for Space Exploration Program and the Qian Xuesen Laboratory,China Academy of Space Technology。
文摘Nowadays,the rapid development of the social economy inevitably leads to global energy and environmental crisis.For this reason,more and more scholars focus on the development of photocatalysis and/or electrocatalysis technology for the advantage in the sustainable production of high-value-added products,and the high efficiency in pollutants remediation.Although there is plenty of outstanding research has been put forward continuously,most of them focuses on catalysis performance and reaction mechanisms in laboratory conditions.Realizing industrial application of photo/electrocatalytic processes is still a challenge that needs to be overcome by social demand.In this regard,this review comprehensively summarized several explorations in thefield of photo/electrocatalytic reduction towards potential industrial applications in recent years.Special attention is paid to the successful attempts and the current status of photo/electrocatalytic water splitting,carbon dioxide conversion,resource utilization from waste,etc.,by using advanced reactors.The key problems and challenges of photo/electrocatalysis in future industrial practice are also discussed,and the possible development directions are also pointed out from the industry view.
基金supported by the National Key Research and Development Program of China(No.2023YFC2907600)the National Natural Science Foundation of China(Nos.42077267,42277174 and 52074164)+2 种基金the Natural Science Foundation of Shandong Province,China(No.ZR2020JQ23)the Opening Project of State Key Laboratory of Explosion Science and Technology,Beijing Institute of Technology(No.KFJJ21-02Z)the Fundamental Research Funds for the Central Universities,China(No.2022JCCXSB03).
文摘The technology of drilling tests makes it possible to obtain the strength parameter of rock accurately in situ. In this paper, a new rock cutting analysis model that considers the influence of the rock crushing zone(RCZ) is built. The formula for an ultimate cutting force is established based on the limit equilibrium principle. The relationship between digital drilling parameters(DDP) and the c-φ parameter(DDP-cφ formula, where c refers to the cohesion and φ refers to the internal friction angle) is derived, and the response of drilling parameters and cutting ratio to the strength parameters is analyzed. The drillingbased measuring method for the c-φ parameter of rock is constructed. The laboratory verification test is then completed, and the difference in results between the drilling test and the compression test is less than 6%. On this basis, in-situ rock drilling tests in a traffic tunnel and a coal mine roadway are carried out, and the strength parameters of the surrounding rock are effectively tested. The average difference ratio of the results is less than 11%, which verifies the effectiveness of the proposed method for obtaining the strength parameters based on digital drilling. This study provides methodological support for field testing of rock strength parameters.
文摘针对目前恶意软件检测分类方法在特征提取、检测准确率等方面面临的挑战,提出一种基于API分组重构与图像表示的恶意软件检测分类方法。首先,对恶意软件调用的API类别统一编号,将API指令序列中相同编号的API聚合为同一API组,根据恶意软件运行时各类API的首次调用顺序对API组重排序,将各API组的条目数记录为该类API对软件样本的贡献度。经分组重构后,各API组按序组织,其顺序为软件样本调用各类API的顺序。各API组内部有序,其内部各API的排列顺序即为软件样本对单个API的调用顺序。有序化的API分组有助于API指令序列信息的图像化表达。基于重组的API指令序列提取API编号作为全局特征列表、API贡献度作为局部特征列表、API顺序索引作为时序特征列表,对特征列表进行标准化与零填充,转化为统一尺寸的特征数组。其中,API编号能清晰地标识API类别,API贡献度可以表征该API的调用频繁程度,API顺序索引可区分各API被调用的顺序。然后,分别用3类特征数组填充RGB图像的3个通道,生成3通道的API编号贡献度及顺序索引特征图像(Feature image of API code devotion and sequential index,FimgCDS)。最后,将Fimg CDS特征图像输入自主构建的轻量型恶意软件特征图像卷积神经网络(malware feature image convolutional neural network,MficNN)分类器,实现对恶意软件的检测与分类。实验结果表明,本文方法在两类数据集上的检测分类准确率分别为98.66%和98.35%,具有较高的恶意软件检测分类性能指标和检测分类速度。
基金The authors would like to acknowledge the support from the Natural Sciences and Engineering Research Council of Canada in the form of Discovery Grants to ARR and SS(RGPIN-2019-07246 and RGPIN-2022-04988).A.Rosenkranz greatly acknowledges the financial support given by ANID-Chile within the project Fondecyt Regular 1220331 and Fondequip EQM190057.B.Wang gratefully acknowledges the financial support given by the Alexander von Humboldt Foundation.
文摘Flexible sensors based on MXene-polymer composites are highly prospective for next-generation wearable electronics used in human-machine interfaces.One of the motivating factors behind the progress of flexible sensors is the steady arrival of new conductive materials.MXenes,a new family of 2D nanomaterials,have been draw-ing attention since the last decade due to their high electronic conduc-tivity,processability,mechanical robustness and chemical tunability.In this review,we encompass the fabrication of MXene-based polymeric nanocomposites,their structure-property relationship,and applications in the flexible sensor domain.Moreover,our discussion is not only lim-ited to sensor design,their mechanism,and various modes of sensing platform,but also their future perspective and market throughout the world.With our article,we intend to fortify the bond between flexible matrices and MXenes thus promoting the swift advancement of flexible MXene-sensors for wearable technologies.
文摘Background: Bilayer artificial dermis promotes wound healing and offers a treatment option for chronic wounds. Aim: Examine the clinical efficacy of bilayer artificial dermis combined with Vacuum Sealing Drainage (VSD) technology in the treatment of chronic wounds. Method: From June 2021 to December 2023, our hospital treated 24 patients with chronic skin tissue wounds on their limbs using a novel tissue engineering product, the bilayer artificial dermis, in combination with VSD technology to repair the wounds. The bilayer artificial dermis protects subcutaneous tissue, blood vessels, nerves, muscles, and tendons, and also promotes the growth of granulation tissue and blood vessels to aid in wound healing when used in conjunction with VSD technology for wound dressing changes in chronic wounds. Results: In this study, 24 cases of chronic wounds with exposed bone or tendon larger than 1.0 cm2 were treated with a bilayer artificial skin combined with VSD dressing after wound debridement. The wounds were not suitable for immediate skin grafting. At 2 - 3 weeks post-treatment, good granulation tissue growth was observed. Subsequent procedures included thick skin grafting or wound dressing changes until complete wound healing. Patients were followed up on average for 3 months (range: 1 - 12 months) post-surgery. Comparative analysis of the appearance, function, skin color, elasticity, and sensation of the healed chronic wounds revealed superior outcomes compared to traditional skin fl repairs, resulting in significantly higher satisfaction levels among patients and their families. Conclusion: The application of bilayer artificial dermis combined with VSD technology for the repair of chronic wounds proves to be a viable method, yielding satisfactory therapeutic effects compared to traditional skin flap procedures.
文摘The purpose of this study was to investigate the clinical application of severe acute respiratory distress syndrome coronavirus-2(SARS-CoV-2)specific antibody detection and anti-SARS-CoV-2 specific monoclonal antibodies(mAbs)in the treatment of coronavirus infectious disease 2019(COVID-19).The dynamic changes of SARS-CoV-2 specific antibodies during COVID-19 were studied.Immunoglobulin M(IgM)appeared earlier and lasted for a short time,while immunoglobulin G(IgG)appeared later and lasted longer.IgM tests can be used for early diagnosis of COVID-19,and IgG tests can be used for late diagnosis of COVID-19 and identification of asymptomatic infected persons.The combination of antibody testing and nucleic acid testing,which complement each other,can improve the diagnosis rate of COVID-19.Monoclonal anti-SARS-CoV-2 specific antibodies can be used to treat hospitalized severe and critically ill patients and non-hospitalized mild to moderate COVID-19 patients.COVID-19 convalescent plasma,highly concentrated immunoglobulin,and anti-SARS-CoV-2 specific mAbs are examples of anti-SARS-CoV-2 antibody products.Due to the continuous emergence of mutated strains of the novel coronavirus,especially omicron,its immune escape ability and infectivity are enhanced,making the effects of authorized products reduced or invalid.Therefore,the optimal application of anti-SARS-CoV-2 antibody products(especially anti-SARS-CoV-2 specific mAbs)is more effective in the treatment of COVID-19 and more conducive to patient recovery.
基金Project supported by the National Key Research and Development Project of China (Grant No.2021YFB3602404)part by the National Natural Science Foundation of China (Grant Nos.61904135 and 62234009)+4 种基金the Key R&D Program of Guangzhou (Grant No.202103020002)Wuhu and Xidian University special fund for industry-university-research cooperation (Grant No.XWYCXY-012021014-HT)the Fundamental Research Funds for the Central Universities (Grant No.XJS221110)the Natural Science Foundation of Shaanxi,China (Grant No.2022JM-377)the Innovation Fund of Xidian University (Grant No.YJSJ23019)。
文摘Improved radio-frequency(RF)power performance of InAlN/GaN high electron mobility transistor(HEMT)is achieved by optimizing the rapid thermal annealing(RTA)process for high-performance low-voltage terminal applications.By optimizing the RTA temperature and time,the optimal annealing condition is found to enable low parasitic resistance and thus a high-performance device.Besides,compared with the non-optimized RTA HEMT,the optimized one demonstrates smoother ohmic metal surface morphology and better heterojunction quality including the less degraded heterojunction sheet resistance and clearer heterojunction interfaces as well as negligible material out-diffusion from the barrier to the channel and buffer.Benefiting from the lowered parasitic resistance,improved maximum output current density of 2279 mA·mm^(-1)and higher peak extrinsic transconductance of 526 mS·mm^(-1)are obtained for the optimized RTA HEMT.In addition,due to the superior heterojunction quality,the optimized HEMT shows reduced off-state leakage current of 7×10^(-3)mA·mm^(-1)and suppressed current collapse of only 4%,compared with those of 1×10^(-1)mA·mm^(-1)and 15%for the non-optimized one.At 8 GHz and V_(DS)of 6 V,a significantly improved power-added efficiency of 62%and output power density of 0.71 W·mm^(-1)are achieved for the optimized HEMT,as the result of the improvement in output current,knee voltage,off-state leakage current,and current collapse,which reveals the tremendous advantage of the optimized RTA HEMT in high-performance low-voltage terminal applications.
基金by Undergraduate Innovation and Entrepreneurship Training Program of Anhui Province(S202312216042)Natural Science Key Research Project of Colleges and Universities in Anhui Province(2023AH051816)General Teaching Research Project of Anhui Province(2022jyxm665).
文摘An analytic hierarchy process(AHP)was employed to assess the applicability of 18 new and superior varieties of flowers in Hefei City flower border applications.A total of 12 indicators were selected from three distinct aspects of adaptability,ornamental characteristics and use traits,in order to establish a comprehensive evaluation model.The results demonstrate that grade I(J≥2.685)exhibits excellent application value,encompassing six species of plants,such asHydrangeamacrophylla‘Endless Summer’;grade II(2.684≤J≤2.420)is also of notable application value,encompassing five species of plants,such asCallistemonrigidus;grade III(2.419≤J≤2.615)is of average application value,including five species of plants,such asCrocosmiacrocosmiflora;grade IV(J≤2.16)is of relatively poor application value.The evaluation results may be utilized as a theoretical reference for the promotion of new and superior varieties in the flower border of Hefei.