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Study on the Propagation and Focusing Mechanism of Long Waves over A Submerged Atoll
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作者 FU Dan-juan LIU Bi-jin +2 位作者 ZHENG Jin-hai WANG Gang CHEN Bi-qin 《China Ocean Engineering》 SCIE EI CSCD 2023年第2期204-217,共14页
An analytical solution for long waves propagating over a submerged atoll is established. The atolls involved in this study are annular coral reefs with large lagoons in the middle, and the expression of the cross sect... An analytical solution for long waves propagating over a submerged atoll is established. The atolls involved in this study are annular coral reefs with large lagoons in the middle, and the expression of the cross section is a trinomial function of the radial distance, i.e., h=ar(2s)-br~s+h_0, where s is the positive rational number. This analytical solution extends the theory by Wang et al.(2018) as s is no longer limited to s=2/m, where m is the positive integer. In addition, by adjusting the terrain parameters properly, the analytic solution can be degenerated to describe the wave propagation over topography with a hump or pit. According to the relationship between wave rays and wave energy, the distribution characteristics and formation mechanism of energy over the topography are expounded. When the lagoon is non-existent, all wave rays converge at the x-axis, which results in an abrupt amplification of the wave amplitude around the convergence point. When a lagoon is mounted on the top of the atoll, the rays are scattered due to the refraction of the lagoon, and only some rays converge at the symmetrical axis and the ridges on both sides,which results in the amplification of wave amplitudes in these areas. 展开更多
关键词 long waves analytic solution wave scattering submerged atoll wave propagation
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Asymmetric chlorophyll responses enhanced by internal waves near the Dongsha Atoll in the South China Sea
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作者 Meilin WU Huijie XUE Fei CHAI 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2023年第2期418-426,共9页
Internal waves(IWs)are small-scale physical processes that occur frequently in stratified marginal seas.IWs are ubiquitous and well documented in the northern South China Sea(n SCS),but few studies have explored the e... Internal waves(IWs)are small-scale physical processes that occur frequently in stratified marginal seas.IWs are ubiquitous and well documented in the northern South China Sea(n SCS),but few studies have explored the ecosystem responses to the IWs.MODISA chlorophyll-a(Chl-a)data from 2002 to 2014 were used to examine the distribution of Chl a near the Dongsha Atoll(DSA).Composite Chl a from about 40 IWs during spring and summer showed stronger response on the northern side than on the southern side of the DSA.One day after the passage of IWs,composite surface Chl a on the northern side increased from 0.11 mg/m3 to a maximum mean value of 0.18 mg/m3.It decreased to 0.13 mg/m3 after two days and maintained that level for several days after the passage of IWs.The enhanced surface Chl a likely caused subsurface Chl-a maximum and nutrients in the surface layer.Approximately 64%of the increase in surface Chl a was due to the uplift of the subsurface Chl-a maximum one day after the passage of IWs,while nutrient-induced new phytoplankton growth contributed about 18%of the increase a few days later.When the IWs occurred frequently in spring and summer,Chl-a level on the northern side was about 30%higher than that on the southern side.IW dissipation and its impact on nutrients and chlorophyll were stronger on the northern side of the DSA than on the south,which caused a north-south asymmetric distribution of Chl a in the region. 展开更多
关键词 internal waves(IWs) PHYTOPLANKTON NUTRIENTS Dongsha atoll northern South China Sea
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基于ATOLL仿真的无线传播模型校正浅析 被引量:1
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作者 王广华 李勇 +1 位作者 李懋 曹凡 《通讯世界》 2017年第24期334-335,共2页
本文通过对传播模型校正背景及长沙选点基站传播模型校正实地测试流程的分析介绍,对如何利用ATOLL仿真工具和CW测试设备进行传播模型校正测试作出了有益的探索,并对测试过程中应该注意的事项进行了分享。
关键词 传播模型校正 atoll仿真 CW测试
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The remote sensing composite information of Nansha reef's closed atoll and the model of its spatial structure evolution——Ⅰ 被引量:2
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作者 Liu Baoyin and Wang Yanfeng First Oceanography Institute, State Oceanic Administration, Qingdao 266003, China 《Acta Oceanologica Sinica》 SCIE CAS CSCD 1997年第1期57-70,共14页
Based on the feature of the growth and the local limitation of the Nansha reef's closed atoll, also the related remote sensing information of it, the composite analysis is made. The closed atoll conception remote ... Based on the feature of the growth and the local limitation of the Nansha reef's closed atoll, also the related remote sensing information of it, the composite analysis is made. The closed atoll conception remote sensing system is constructed through the formation mechanism, development law and the space-time distribution of the closed atoll. Solution of the equation consisting of information function value and isostatic value of closed atoll and half-closed atoll using this system, and topologic analysis on the two kinds of atoll's morphologic growth are the basic foundation for the research of their evolutionary comparative model. 展开更多
关键词 Nansha reefs closed atoll EVOLUTION remote sensing model
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Preliminary studies on methane flux from the ornithogenic soils on Xi-sha atoll, South China Sea 被引量:1
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作者 ZHU Ren-bin SUN Li-guang +3 位作者 ZHAO San-ping XIE Zhou-qing LIU Xiao-dong YIN Xue-bin 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2005年第5期789-793,共5页
Methane flux from the ornithogenic soils was preliminarily measured by closed chamber method on Xi-sha atoll, South China Sea during March 10 to April 11, 2003 for the first time. The CH4 flux ranged from - 226.7 μg/... Methane flux from the ornithogenic soils was preliminarily measured by closed chamber method on Xi-sha atoll, South China Sea during March 10 to April 11, 2003 for the first time. The CH4 flux ranged from - 226.7 μg/(m^2 ·h) to 226.3 μg/(m^· h) at the observation sites on Dong Island. High atmospheric CH4 consumption was observed from the ornithogenic soils on sunny days. CH4 uptake rates showed the highest value after the midday and they had a strong positive correlation with soil temperatures. Under the same weather conditions, the CH4 fluxes were also observed from the intact and disturbed soils on Yongxing Island. Results showed that the intact soils with natural vegetation also showed high atmospheric CH4 consumption and the average flux was - 141.8 μg/( m^2· h). However, disturbed soils via anthropogenic reclamation showed CH4 emissions and the average flux was 441 .7 μg/( m^2· h). Therefore land use changes may have an important effect on the CH4 fluxes from the tropical ornithogenic soils. In addition, different observation sites show a high spatial variation in CH4 fluxes. The wetland in salt marsh showed the CH4 emission on Dong Island, and the dry soil sites all showed high atmospheric CH4 consumption, suggesting that CH4 fluxes were predominantly controlled by soil water regime. The effects of soil chemical properties on CH4 fluxes were also analyzed and discussed in this paper. 展开更多
关键词 METHANE FLUX South China Sea ornithogenic soil Xi-sha atoll
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Natural and Artificial Connections between Atoll Islets in the Pacific,Their Process and Environmental Impact 被引量:2
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作者 XUEChunting RussellHoworth 《Journal of Ocean University of Qingdao》 2003年第2期195-200,共6页
Three types of natural connection between atoll islets are described. Causeway, as an artificial way of connecting islets, makes a connection to be completed in a few months. In this case shore adjustment becomes more... Three types of natural connection between atoll islets are described. Causeway, as an artificial way of connecting islets, makes a connection to be completed in a few months. In this case shore adjustment becomes more vigorous than that in natural conditions, resulting in lagoon shore erosion. A causeway without short bridges or culverts should be built close to the lagoon shore to reduce lagoon shore erosion. A causeway-crossing channel assemblage is the worst type among all of the connection engineering constructions because the crossing channel traps sediment and further transports it out of the channel, resulting in long period coastal erosion. Reforming Nippon Causeway in Tarawa Atoll, Kiribati by simple means will stop sand loss, reduce shore erosion and greatly upgrade its stability. 展开更多
关键词 atoll environment impact causeway coastal erosion
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Zooplankton in the Huangyan Atoll,South China Sea:A comparison of community structure between the lagoon and seaward reef slope 被引量:1
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作者 LI Kaizhi KE Zhixin TAN Yehui 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2018年第5期1671-1680,共10页
Relatively few studies have investigated the community structure of zooplankton in the atolls of the central South China Sea. Zooplankton were sampled at nine stations within the lagoon and four facing the seaward ree... Relatively few studies have investigated the community structure of zooplankton in the atolls of the central South China Sea. Zooplankton were sampled at nine stations within the lagoon and four facing the seaward reef-slope in the Huangyan Atoll during May 2015. Lagoonal samples contained 48 zooplankton taxa( H' =2.25±0.95; J =0.70±0.23) with planktonic larvae, copepods, and euphausids contributing 95.63% of total abundance. Seaward oceanic samples contained 114 zooplankton(H ' =5.27±0.27; J =0.90±0.03) with copepods, siphonophores, chaetognaths, appendicularians, and planktonic larvae accounting for 93.66% of abundance. Lagoonal zooplankton abundance was lower than that on the seaward reef-slope. Zooplankton community dif fered significantly between the lagoon and reef-slope groups(R =0.708, P =0.001). The former was dominated by Macruran larvae, Brachyuran larvae, S tylocheiron carinatum, and Acartia spp., while the latter was predominately represented by O ikopleura longicauda, Chelophyes contorta and C opilia mirabilis. Chlorophyll a concentration was significantly higher in the lagoon than the reef slope regions( P <0.01), which may be due to the nutrient input from fishing vessels near the lagoon mouth. Zooplankton abundance was negatively correlated with chlorophyll a concentration(P <0.01). A clear dif ference was observed statistically in the species composition and abundance of zooplankton between the lagoon and the seaward slope at Huangyan Atoll, which suggests that it may be resulted from the influence by natural and anthropogenic interactions. 展开更多
关键词 ZOOPLANKTON community composition abundance atoll South China Sea
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Preliminary studies on nitrous oxide emissions from the ornithogenic soils on Xi-sha atoll,South China Sea 被引量:1
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作者 ZHURen-bin SUNLi-guang ZHAOSan-ping XIEZhou-qing LIUXiao-dong YINXue-bin 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2005年第4期551-556,共6页
The preliminary measurements of nitrous oxide fluxes from the ornithogenic soils on tropical Xi-sha atoll were made using a closed chamber technique for the first time. N_2O fluxes from the ornithogenic soils ranged f... The preliminary measurements of nitrous oxide fluxes from the ornithogenic soils on tropical Xi-sha atoll were made using a closed chamber technique for the first time. N_2O fluxes from the ornithogenic soils ranged from 1 8 to 40 3 μg/(m^2\5h) on Dong Island and 3 2 to 20 4 μg/(m^2·h) on Yongxing Island and their flux averaged 11 0 μg/(m^2·h) and 8 3 μg/(m^2·h), respectively. N_2O fluxes from two wetland sites in salt marsh of Dong Island were approximately one order of magnitude lower than those from the ornithogenic soils and averaged 2 1 μg/(m^2·h) and 2 4 μg/(m^2·h). The diurnal variation cycle in the fluxes was obtained at the observation sites; the N_2O flux increased with the increase in soil temperature. The sudden increase in soil moisture greatly stimulated N_2O emission from the ornithogenic soils on Dong Island due to the heavy rainfall. The undisturbed soils showed the lower N_2O fluxes and the average was 4 8 μg/(m^2·h) and the soils via the reclamation showed the higher N_2O fluxes and the average was 16 6 μg/(m^2·h) on Yongxing Island, suggesting that the changes of land use have an important effect on N_2O fluxes from the ornithogenic soils. In addition, the N_2O fluxes at the different sites showed high spatial variations. The fluxes were positively correlated with the concentrations of NO^-_3, PO~ 3- _4 and Mn in the soils. The negative correlation between the fluxes and total S concentration in the ornithogenic soils was also found for the first time. Coastal soils or sediments constitute an important source of global atmospheric N_2O and the increases in nitrogen loading from seabird guanos will lead to significant increases in the flux of this atmospherically active gas. 展开更多
关键词 South China Sea ornithogenic soil nitrous oxide Xi-sha atoll emission
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Analysis on coral reefs mapping using SPOT5 data at the Dongsha Atoll 被引量:1
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作者 CHEN Jianyu MAO Zhihua ZHANG Huaguo WU Junping CHEN Xiaodong PAN Delu 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2007年第2期26-35,共10页
Coral reefs are an sensitive-to-environment complex marine ecosystem. The ecosystem of corals is rich in biodiversity. Remote sensing offers a powerful tool for categorizing coral reefs and is the most cost - effectiv... Coral reefs are an sensitive-to-environment complex marine ecosystem. The ecosystem of corals is rich in biodiversity. Remote sensing offers a powerful tool for categorizing coral reefs and is the most cost - effective approach for the large - scale reef survey. The Dongsha Atoll, more than 300 km2 with an average depth of 10 m, is located at the northern continental margin of the South China Sea. It has been abused by destructive fishing during recent decades. Three satellite imageries (Quickbird2, ETM + and SPOTS) are used to evaluate the capabilities of SPOT5 imagery to provide data that are useful for categorizing the current distribution of coral reefs therein. During the data processing, unsupervised classification functions are adopted for ETM + and SPOT5 data, while the supervised classification method is used for Quickbird2. The classes are (or not) merged into coral reef, and then will be operated by vectorization, simplification, and topological analysis. There are 1 331 coral reefs larger than 100 m2 with a detection limit of 3 × 3 pixels at the multi - band data of Quickbird2, which is taken as the comparison baseline. The results extracted from SPOT5 and ETM images are less in number and area than those from the Quickbird2 image, whereas the results from SPOT5 data are better than those of ETM data at the silty lagoon due to its higher resolution. SPOT5 XS band 2 fails to distinguish the deep substrate inside the atoll compared with ETM data because of its poor penetration capability. Only SPOT XS band 1 cannot be used to differentiate coral reef from sand bottom. Merging the SPOT5 multi - bands data with the spatial resolution of SPOT5 pan - data and referring to ETM imagery are expected to provide an optimal satellite - based approach for mapping of coral reefs. 展开更多
关键词 coral reef Dongsha atoll SPOT5 Quickbird2
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基于Atoll的TD-LTE组网方案仿真与现网验证 被引量:15
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作者 何明 高新 宋永胜 《移动通信》 2013年第10期83-86,共4页
首先论述了TD-LTE异频组网、PCI规划、MIMO配置等关键性组网因素,提出网络规划方案;然后通过Atoll仿真软件对方案进行仿真验证其科学性;最后进行现网测试来检验方案的可行性,从而得到科学可行的TD-LTE网络规划设计方案。
关键词 TD-LTE异频组网PCI规划MIMO配置 atoll网络仿真
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基于ATOLL仿真的无线网络结构化分析
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作者 李勇 王广华 《中国新通信》 2017年第22期79-80,共2页
本文利用ATOLL仿真对现网基站进行分类,按照"布局层"、"补盲层"、"吸热层"的分层结构,对现网无线网络的室外站进行梳理,给现网站址打上结构化标签,最终实现在规划、建设、维护、优化各阶段的分层管理。
关键词 atoll仿真 网络结构化 布局层 补盲层 吸热层
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地图精度对基于Atoll的5G网络仿真的影响
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作者 梁雅菁 黄劲安 刘冰寒 《广东通信技术》 2019年第11期53-55,60,共4页
网络仿真可以用于验证规划设计方案的合理性,而仿真结果受输入参数、传播模型、地图精度等诸多因素的影响。在合理控制变量的基础上,基于Atoll仿真软件,研究不同电子地图精度对5G网络仿真结果的影响,总结出5G网络仿真对地图精度要求更... 网络仿真可以用于验证规划设计方案的合理性,而仿真结果受输入参数、传播模型、地图精度等诸多因素的影响。在合理控制变量的基础上,基于Atoll仿真软件,研究不同电子地图精度对5G网络仿真结果的影响,总结出5G网络仿真对地图精度要求更高的结论,并提出不同场景下5G仿真使用的地图精度建议。 展开更多
关键词 仿真 5G 地图精度 atoll
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基于Atoll的PCI规划仿真验证与分析
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作者 杨文良 王静 李盼星 《数据通信》 2014年第6期15-17,21,共4页
PCI(Physical Cell ID,物理小区标识)是LTE(Long Term Evolution,长期演进)中与小区相关的两种标识之一,用于UE识别e Node B小区。文章首先对PCI与参考信号、同步信号及其他物理信道的关系进行理论分析,其次使用Atoll软件对PCI模三干扰... PCI(Physical Cell ID,物理小区标识)是LTE(Long Term Evolution,长期演进)中与小区相关的两种标识之一,用于UE识别e Node B小区。文章首先对PCI与参考信号、同步信号及其他物理信道的关系进行理论分析,其次使用Atoll软件对PCI模三干扰进行仿真验证并对结果进行分析,最后提出PCI网络规划建议。 展开更多
关键词 LTE PCI规划 atoll
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Evolution of the Late Miocene atoll systems offshore Xisha Islands 被引量:3
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作者 KUANG ZengGui GUO YiQun +2 位作者 WANG LiaoLiang LIANG JinQiang SHA ZhiBin 《Science China Earth Sciences》 SCIE EI CAS 2014年第12期3084-3096,共13页
Modern atolls have been studied systematically and thoroughly in the South China Sea.However,the knowledge of a paleo-atoll and related sedimentary system is very limited.Here we used the newly acquired high resolutio... Modern atolls have been studied systematically and thoroughly in the South China Sea.However,the knowledge of a paleo-atoll and related sedimentary system is very limited.Here we used the newly acquired high resolution 2D seismic data,and discovered three late Miocene atoll systems in the offshore Xisha Islands for the first time.We named them atoll system A,B,C,respectively.These three atoll systems,all developed on the horsts dominated by normal fault,consist mainly of atoll reefs,patch reefs,fore-reef slope deposits,and lagoons.On the basis of the interpreted sequence stratigraphic framework and the identification of fore-reef slope deposits,we suggested only the atoll system A continued to grow until Quaternary,and both of atoll system B and C had been drowned in Pliocene.In late Miocene,the atoll systems in the study area were most developed,either in magnitude or in maturity,which indicated late Miocene was the most flourishing period of reef builders,and this was in accordance with the drilling result of ODP Leg 184 in the South China Sea.Pliocene was an important reef drowning period in the study area,and both atoll systems B and C were drowned and hemipelagic deposits prevailed gradually.Quaternary was another reef drowning period in the study area,two large atoll reefs grown on the atoll system A were finally drowned,and hemipelagic deposits begun to drape and fill the palaeo-atoll systems.The growth and drowning of atolls are controlled mainly by tectonic subsidence in long term,but global eustatic can impact it in short term also. 展开更多
关键词 offshore Xisha Islands atoll system DROWNING EVOLUTION
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Atoll(珊瑚礁)IN80放大器和CD80 CD机
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《高保真音响》 2004年第6期6-6,共1页
关键词 atoll公司 IN80 放大器 CD80 CD机
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Optimization of Mobile Network Radio Coverage by Automating Radio Parameter Updates Using Parsing
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作者 Patrick Dany Bavoua Kenfack Alphonse Binele Abana +2 位作者 Emmanuel Tonye Nadège Laure Bemehemie William Tchofo Tchouleko 《Journal of Computer and Communications》 2023年第4期79-102,共24页
The present work aims is to propose a solution for automating updates (MAJ) of the radio parameters of the ATOLL database from the OSS NetAct using Parsing. Indeed, this solution will be operated by the RAN (Radio Acc... The present work aims is to propose a solution for automating updates (MAJ) of the radio parameters of the ATOLL database from the OSS NetAct using Parsing. Indeed, this solution will be operated by the RAN (Radio Access Network) service of mobile operators, which ensures the planning and optimization of network coverage. The overall objective of this study is to make synchronous physical data of the sites deployed in the field with the ATOLL database which contains all the data of the coverage of the mobile networks of the operators. We have made an application that automates, updates with the following functionalities: import of radio parameters with the parsing method we have defined, visualization of data and its export to the Template of the ATOLL database. The results of the tests and validations of our application developed for a 4G network have made it possible to have a solution that performs updates with a constraint on the size of data to be imported. Our solution is a reliable resource for updating the databases containing the radio parameters of the network at all mobile operators, subject to a limitation in terms of the volume of data to be imported. 展开更多
关键词 Radio Parameters PARSING atoll Database OSS NetAct ETL
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地质记录中的海水白云岩化作用 被引量:19
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作者 朱同兴 黄志英 《沉积与特提斯地质》 CAS CSCD 1993年第5期16-26,共11页
地质记录中的海水白云岩化作用是广泛存在的。它不仅发育于时代较新的始新世地层内(如太平洋中的 Enewetak 珊瑚岛地区),而且也发育于时代较老的震旦纪灯影期地层内(如云南东北部地区)。在以前的白云岩成因研究过程中,海水白云岩化作用... 地质记录中的海水白云岩化作用是广泛存在的。它不仅发育于时代较新的始新世地层内(如太平洋中的 Enewetak 珊瑚岛地区),而且也发育于时代较老的震旦纪灯影期地层内(如云南东北部地区)。在以前的白云岩成因研究过程中,海水白云岩化作用的普遍性和重要性被大大地低估了。自从 Saller(1984)首次报道了正常海水白云岩化的实例以来,海水白云岩化作用的研究已取得了长足的进展,如 Kasner(1984);Land(1985);Smart(1988);Tucker(1990);朱同兴、罗安屏(1993)等。近年来,作者通过对云南东北部地区震旦系灯影组潮缘沉积物的岩石学、沉积相、古地理格局和沉积地球化学标志等综合研究,认为该套巨厚的白云岩层(400—1000m)的成因不是原生的,而是成岩交代形成的,其主要的形成机制之一就是成岩早期的海水白云岩化作用。海水白云岩化作用的发育主要受海平面变化、沉积作用类型以及古气候等条件的限制。造成滇东北地区灯影期海水白云岩化作用的主要机制可能是位于其西北部的青藏大洋内的冷洋流向东部沉积物内泵吸,和位于其东南缘的扬子边缘海的海水向西部沉积物内循环对流(柯特对流)。上述的泵吸作用与对流作用的相互叠加可使巨大体积的海水通过扬子海域,尤其是扬子台地西南边缘(滇东北地区)沉积物,从而使其发生巨大规模的海水白云岩化作用。由海水白云岩化作用形成的白云岩的结构有序度中等,I=0.68—0.82,其碳、氧同位素组成均显示海水碳酸盐来源,δ^(13)=+1.8—+2.6‰(PDB),δ^(18)O=+2.1—+2.7‰(PDB)(冷洋流来源,Enewetak Atoll,始新统)或-5.1—-6.5‰(受地热和大气淡水双重影响而偏负值,滇东北地区;灯影组)。灯影期海水白云岩化作用模式合理地解释了区域巨厚沉积物的块状白云岩化成因、充足的镁离子来源以及多余的钙离子的搬运等白云岩成因研究过程中的关键性问题。 展开更多
关键词 白云岩化作用模式 海水白云岩化作用 Enewetak atoll 始新统 云南东北部 灯影组
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无线仿真在基站搬迁评估中的应用
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作者 刘学武 《江苏通信》 2021年第1期49-53,共5页
将无线仿真工具应用于移动通信基站搬迁影响的评估,利用仿真基础覆盖预测功能,快速仿真基站拆除前后面覆盖率等状况对比,并通过仿真软件的自动布站和站址优化功能,为下一步该处区域补站规划、参数优化提供了科学依据和方向。
关键词 无线仿真 基站 搬迁 评估 atoll
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密集市区LTE无线网络规划及仿真研究 被引量:5
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作者 吴彦 胡双红 罗宏 《湖南邮电职业技术学院学报》 2014年第3期13-17,共5页
LTE作为准4G技术,为用户带来移动互联网业务的全新体验。该论文首先根据建设要求和系统特征,对数据流量较高的某密集市区进行LTE无线网络的初步规划,然后利用Atoll软件运行仿真,由信号覆盖强度预测图,信干噪比值覆盖分布图和下行吞吐量... LTE作为准4G技术,为用户带来移动互联网业务的全新体验。该论文首先根据建设要求和系统特征,对数据流量较高的某密集市区进行LTE无线网络的初步规划,然后利用Atoll软件运行仿真,由信号覆盖强度预测图,信干噪比值覆盖分布图和下行吞吐量覆盖分布图可知,该规划方案可以达到无线网络规划目标。 展开更多
关键词 LTE 无线网络规划 atoll仿真
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Aml1基因异常与儿童急性白血病相关研究进展 被引量:2
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作者 王晓东 陈静 《中国实验血液学杂志》 CAS CSCD 2009年第4期1078-1082,共5页
诸多研究发现细胞遗传学改变在急性白血病发生中起重要作用。其中以涉及aml1基因的改变最为常见。aml1基因为正常造血必需基因之一,在儿童急性白血病中约1/3以上的患儿可以检测到aml1基因的异常,其中t(12;21)和t(4;21)主要见于儿童急性... 诸多研究发现细胞遗传学改变在急性白血病发生中起重要作用。其中以涉及aml1基因的改变最为常见。aml1基因为正常造血必需基因之一,在儿童急性白血病中约1/3以上的患儿可以检测到aml1基因的异常,其中t(12;21)和t(4;21)主要见于儿童急性淋巴细胞白血病。期望通过对儿童急性白血病中aml1基因易位的研究,能够揭示儿童急性白血病发生的机制,为儿童急性白血病的临床诊断治疗提供新的靶点。本文就aml1基因的结构与功能,儿童急性淋巴细胞白血病中aml1基因异常和儿童急性髓系白血病中aml1基因异常等问题的研究进展作一综述。 展开更多
关键词 儿童急性白血病 atoll tel—aml1 aml1—eto
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