Morphology prediction of dihydroxylammonium 5,5'-bistetrazole-1,1'-diolate (TKX-50) crystal in different solvent systems using modified attachment energy model

In order to theoretically study the growth morphology of dihydroxylammonium 5,5’-bistetrazole-1,1’-dio late(TKX-50)crystal in different solvent systems,crystal–solvent models were established,and then molecular dynamics(MD)methods were adopted as a means to simulate particle motion.Modified attachment energy(MAE)model was employed to calculate the growth morphology of TKX-50.The simulation results demonstrate that COMPASS force field and RESP charge are suitable for molecular dynamics simulation of TKX-50.The morphologically dominant growth surfaces of TKX-50 in vacuum are(020),(011),(11–1),(100)and(120),respectively.In water(H_(2)O)and N,N-dimethylformamide(DMF)solvents,the(11–1)face is the largest in the habit face,the growth rate of(020)face becomes faster.With the increase of temperature,the aspect ratios of TKX-50 crystal in DMF solvent increase,and the areas of the(120)faces decrease.In ethylene glycol/H_(2)O mixed solvent system with volume ratio of 1/1,aspect ratio of TKX-50 is relatively small.In formic acid/H_(2)O mixed solvents with different volume ratios(1/4,1/3,1/2,1/1 and 2/1),aspect ratio of TKX-50 is relatively small when volume ratio is 1/2.

Numerical Study on the Pulsation Characteristics of An Attached Air Bubble Under A Nearby Oscillating Bubble

Numerical simulations of the non-spherical evolution of a pulsating bubble interacting with a stationary air bubble attached to a fixed structure were performed using a three-dimensional boundary integral method by implementing the mirror image method to simplify the processing of the numerical model. Code validation was accomplished by comparing the numerical results with the laboratory experimental data obtained in our previous study. Complex phenomena were observed, including three types of bubble jet forms, which depended strongly on the distance parameter with respect to the initial location of the bubble from the plate, the bubble strength parameter and the initial air bubble radius parameters. The results of the simulations provide detail insight into interesting bubble jetting phenomena,such as bubble splitting, jets moving away from the plate, and bubble shedding. The dimensionless distance parameter and the initial air bubble radius parameter play a major role in determining the shapes of two bubbles and the jetting direction. The air bubble strength parameter did not change the bubble jet direction but influenced the bubble shape.The detachment of the attached air bubble under oscillating bubble suction was easily observed for a small initial air bubble. These results showed that bubble jetting toward the plate was manipulated through the effect of attached air bubble, and that cavitation-based applications and underwater explosion bubble may benefit from this erosion mitigation approach.

Cytokine changes and embryo attachment in mouse endometrial cells following treated with peripheral blood mononuclear cells(PBMCs)expressing ectopic hCG,and hCG-activated PBMCs

Objective:To compare the effect of human chorionic gonadotropin(hCG)-producing peripheral blood mononuclear cells(PBMCs)and PBMCs activated by hCG in vitro and expressions of related immune genes in mouse implantation.Methods:hCG-producing PBMCs(transfected PBMC)and PBMCs activated by hCG in vitro were introduced into isolated mouse endometrial cells,while cell cultures were divided into four groups:the control,PBMC,transfected,and activated PBMC groups.The expression of studied genes(IL-1β,IL-6,Lif,and Vegf)was evaluated and blastocyst attachment on the cocultured cells(isolated endometrial cells and PBMC cells)was monitored in all four groups.Results:Data showed that expression decreased in the PBMC group compared to the treated PBMC(transfected and activated PBMCs)and increased in transfected PBMC compared to the activated PBMC.Attachment and migration of blastocysts were dramatically enhanced in the transfected PBMC group compared to the activated PBMC group(P<0.05).Conclusions:Use of hCG-producing PBMCs(transfected PBMC)has more influence on endometrial receptivity.

Relationship between Parent-Child Attachment and Problem Behaviors among Chinese Firstborn Children in Family Transitions: A Meta-Analysis

The implementation of China’s three-child fertility policy has led to a notable increase in multiple-child families.Notably,firstborn children experience a significant transition from being an only child to a non-only child.This transition is associated with problematic behaviors,affecting their social adjustment,sibling relationships,and family harmony.Although several studies have examined the relationship between parent-child attachment and problem behaviors exhibited byfirstborn children during family transitions,thefindings have been inconsistent.Hence,a meta-analytic study was undertaken to elucidate the inconsistencies in this relationship and explore the moderating factors that may contribute to these discrepancies.Using a systematic literature retrieval and screening method,12 effect sizes were derived from the 10 eligible articles,encompassing a sample size of 5319.The meta-analysis demonstrated a low negative association between parent-child secure attachment and problem behaviors exhibited byfirstborn children during family transitions.Furthermore,the present study investigates potential moderator factors,such as children’s age and geographic region,to gain a more nuanced understanding of the relationship.Consequently,the establishment of parent-child attachment relationships has the potential to mitigate problem behaviors observed infirst-born children during family transitions.The implications of thesefindings indicate that parents can nurture secure attachment bonds with their children by demonstrating sensitive responsiveness,employing positive parenting practices,and fostering emotional availability.These efforts contribute to the cultivation of secure internal working models and positive behavioral manifestations withinfirst-born children,which in turn affect their relationships with siblings.

Landscape Upgrading and Transformation of Old Urban Parks from the Perspective of Place Attachment:A Case Study of Nanchang Bayi Park

On the basis of combing the relevant theories of place attachment, the planning framework of upgrading and reconstruction of old parks based on place attachment was put forward. Taking Nanchang Bayi Park as an example, the methods and key points of landscape improvement and transformation of old urban parks based on place attachment were explained to provide new ways and references for the renewal of old urban parks.

The Evolving Bipartite Network and Semi-Bipartite Network Models with Adjustable Scale and Hybrid Attachment Mechanisms

The bipartite graph structure exists in the connections of many objects in the real world, and the evolving modeling is a good method to describe and understand the generation and evolution within various real complex networks. Previous bipartite models were proposed to mostly explain the principle of attachments, and ignored the diverse growth speed of nodes of sets in different bipartite networks. In this paper, we propose an evolving bipartite network model with adjustable node scale and hybrid attachment mechanisms, which uses different probability parameters to control the scale of two disjoint sets of nodes and the preference strength of hybrid attachment respectively. The results show that the degree distribution of single set in the proposed model follows a shifted power-law distribution when parameter r and s are not equal to 0, or exponential distribution when r or s is equal to 0. Furthermore, we extend the previous model to a semi-bipartite network model, which embeds more user association information into the internal network, so that the model is capable of carrying and revealing more deep information of each user in the network. The simulation results of two models are in good agreement with the empirical data, which verifies that the models have a good performance on real networks from the perspective of degree distribution. We believe these two models are valuable for an explanation of the origin and growth of bipartite systems that truly exist.

Anchor Attachment蛋白在结直肠癌中表达增强

目的探讨Anchor Attachment蛋白(AAP)的表达与结直肠癌浸润、转移的关系及临床意义。方法免疫组织化学法检测AAP的表达,分析AAP表达水平与肿瘤临床病理特征之间的关系;并用酶联免疫吸附(ELISA)法检测血清中AAP表达水平。结果结直肠正常肠黏膜、癌原发灶、淋巴结和肝转移灶中AAP的表达阳性率分别为20.5%、53.0%、69.8%和80.0%;癌原发灶、转移淋巴结和肝转移灶中AAP表达阳性率均显著高于正常肠黏膜组织(P<0.01),转移淋巴结和肝转移灶中AAP阳性率高于癌原发灶(P<0.05);淋巴结转移患者和肝转移患者的原发灶AAP阳性率显著高于无转移者(P<0.01);Dukes分期A、B、C、D期患者AAP阳性率逐渐增高,各分期之间差异显著(P<0.01)。83例结直肠癌患者血清AAP水平为(6.3±2.8)μg/L,显著高于30例健康志愿者的(2.2±0.9)μg/L,(t=6.976,P<0.01);Dukes分期A、B期患者血清AAP水平为(5.2±2.6)μg/L,显著低于C、D期患者的(7.1±2.9)μg/L(P<0.05)。结论检测外周静脉血AAP水平对预测和判断结直肠癌病情和肝转移有重要意义。

广义逆多项式模的Attached素理想

设R是有单位元1的结合环,(S,≤)是严格全序Artin幺半群,M_R是右R-模,Att(M_R)与Att([M^(S,≤)]_([[R^(S,≤)]]))分别表示模M_R与广义逆多项式模[M^(S,≤)]_([[R^(S,≤)]])的所有Attached素理想组成的集合.该文主要讨论了广义幂级数环[[R^(S;≤)]]广义逆多项式模[[R^(S;≤)]]的Attached素理想的相关性质,证明了在一定条件下,有Att([M^(S,≤)]_([[R^(S,≤)]])={[[PR^(S;≤)]]P∈Att(M_R)}.这一结论表明广义逆多项式模([M^(S,≤)]_([[R^(S,≤)]])的Attached素理想在一定条件下可以用模M_R的Attached素理想来刻画,推广了Annin S在文献[1]中关于斜多项式环上逆多项式模的Attached素理想的相关结论.

Genetics of adult attachment and the endogenous opioid system

Since the pioneering work by Panksepp et al,the neurobiological bases of attachment behavior have been closely linked with opioid neurotransmission.Candidate gene studies of adult individuals have shown that variation in the muopioid receptor gene(OPRM1)influences attachment behavior.Early maternal care and the A/A genotype of the A118G polymorphism interact in modulating levels of fearful attachment.Compared to their counterparts carrying the A/A genotype,individuals expressing the minor 118G allele show lower levels of avoidant attachment and experience more pleasure in social situations.Brain imaging research has strengthened the biological plausibility of candidate gene studies.The avoidance dimension of attachment correlates negatively with muopioid receptor availability in the thalamus and anterior cingulate cortex,as well as the frontal cortex,amygdala,and insula.Overall,findings from human studies combined with those from animal models suggest that research on the genetic bases of attachment should include the endogenous opioid system among the investigated variables.

场所依赖(place attachment):一种游憩行为现象的研究框架

“场所依赖”理论是解释“某些地方与人之间似乎存在着一种特殊的依赖关系”这个客观现象的有效理论工具,并已成为西方休闲和游憩研究的一个热点,而在我国仍然处于空白状态。本文讨论了场所和场所依赖的概念及其发展,介绍了西方场所依赖研究的最新进展。文章的主要贡献包括:(1)首次将以游憩为角度开展研究的场所依赖理论引进我国;(2)用数学方法示意理解场所依赖的结构;(3)构建了场所依赖理论的CDEEM研究框架。文章还探讨了场所依赖理论的应用前景。

Improving bubble-particle attachment during the flotation of low rank coal by surface modification

Based on the problems caused by many oxygen-containing functional groups and poor floatability on the surface of low rank coal,the characteristics of low rank coal were analyzed systematically by means of scanning electron microscopy(SEM),X-ray diffraction(XRD)and X-Ray photoelectron spectroscopy(XPS)techniques.The bubble-particle induction time was used to determine the characterization of the bubble-particle attachment,and the bubble-particle attachment of low rank coal modified by soaking the coal samples in an acid or alkaline solution was analyzed.The floatability of the modified coal surface was verified by flotation tests.The results show that the particle size of 0.125–0.074 mm of the coal sample exhibited better bubble-particle attachment characteristics.The small bubble,the larger approach velocity of bubble and the larger bubble deformation were more helpful to enhance the bubbleparticle attachment.For an acid solution,the smaller the p H was and the longer the soaking time was,the better the floatability of the coal sample and the higher the combustible material recovery were.The combustible material recovery of low rank coal was increased to 78.79%by soaking the sample in an acid solution of pH=0 for 180 min.On the contrary there was a best concentration for the alkaline solution.

Community structure and controlled factor of attached green algae on the Porphyra yezoensis aquaculture rafts in the Subei Shoal, China

This study analyzes the community structure, the quantity changes of the algae and the effect of important environmental factors and estimates the total biomass of the attached green algae in the survey areas. The study uses data from surveys of the attached green algae on the Porphyra yezoensis aquaculture rafts and data regarding the environmental factors from October 2010 to April 2011 in the Subei Shoal. The attached green algae on the rafts included Ulva prolifera, Capsosiphon groenlandicus, U. linza, U. intestinalis, U. clathrata, and U. cornpressa. The biomass changes of the attached green algae exhibited an inverted parabola： the biomass was the highest （14 898 t） in April, and was the second highest （2 034 t） in November; it was lowest in February （only 729 t） and increased sharply from March to April. The species diversity differed significantly among the seasons. In September and October, when the P. yezoensis aquaculture rafts were initially set up, the attached green algae had a high biodiversity, while from December to the next February, a variety of green algae species coexisted on the rafts, although the biomass was low, and from March to April, as the biomass increased sharply, the species diversity dropped to the minimum. During this time, C. groenlandicus was apparently dominant with the maximum biomass proportion up to 80%, while the U. prolifera proportion increased exponentially to 20% to 40%. The water temperature had a direct regulating effect on the biomass and the species succession of the attached green algae. The estimation of the community dynamics and the biomass of the green algae provided the evidence needed to track the origin of the large-scale green tide in the southern Yellow Sea.

Particle size distribution and property of bacteria attached to carbon fines in drinking water treatment

The quantitative change and size distribution of particles in the effluents from a sand filter and a granular activated carbon （GAC） filter in a drinking water treatment plant were investigated. The average total concentration of particles in the sand filter effluent during a filter cycle was 148 particles/mL, 27 of which were larger than 2 μm in size. The concentration in the GAC effluent （561 particles/mL） was significantly greater than that in the sand filter effluent. The concentration of particles larger than 2 μm in the GAC filter effluent reached 201 particles/mL, with the amount of particles with sizes between 2 μm and 15 μm increasing. The most probable number （MPN） of carbon fines reached 43 unit/L after six hours and fines between 0.45 μm and 8.0 μm accounted for more than 50%. The total concentration of outflowing bacteria in the GAC filter effluent, 350 CFU （colony-forming units） /mL, was greater than that in the sand filter effluent, 210 CFU/mL. The desorbed bacteria concentration reached an average of 310 CFU/mg fines. The disinfection efficiency of desorbed bacteria was lower than 40% with 1.5 mg/L of chlorine. The disinfection effect showed that the inactivation rate with 2.0 mg/L of chloramine （90%） was higher than that with chlorine （70%）. Experimental results indicated that the high particle concentration in raw water and sedimentation effluent led to high levels of outflowing particles in the sand filter effluent. The activated carbon fines in the effluent accounted for a small proportion of the total particle amount, but the existing bacteria attached to carbon fines may influence the drinking water safety. The disinfection efficiency of desorbed bacteria was lower than that of free bacteria with chlorine, and the disinfection effect on bacteria attached to carbon fines with chloramine was better than that with only chlorine.

Attachment Styles are Related to ERPs Elicited to Angry Faces in an Oddball Paradigm

Attachment theory suggests that anxious attachment is associated with hypervigilance to threatening social stimuli, and avoidant attachment with avoidance or suppression of processing such stimuli. Twenty-five students viewed angry, fearful and neutral female faces in four visual oddball tasks, and completed the Attachment Style Questionnaire, the Autonomy-Connectedness Scale, and Anxiety and Depression subscales of the Symptom Checklist-90. When the oddballs were angry faces in a background of neutral frequents, we found higher levels of autonomy and secure attachment to be related to larger N100 and smaller P300 amplitudes;higher levels of anxious attachment were, on the contrary, associated with smaller N100 and larger P300 amplitudes. Variation in attachment is related to approaching, or withdrawing from threatening stimuli, and ERP-techniques add to our understanding of how the attachment system actually works.

The contribution of attached Ulva prolifera on Pyropia aquaculture rafts to green tides in the Yellow Sea

Green tides caused by the unusual accumulation of high floating Ulva prolifera have occurred regularly in the Yellow Sea since 2007.The primary source of the Yellow Sea green tides is the attached algae on the Pyropia aquaculture rafts in the Subei Shoal.Ulva prolifera and Blidingia(Italic)sp.are the main species observed on Pyropia aquaculture rafts in the Subei Shoal.We found that U.prolifera has strong buoyancy and a rapid growth rate,which may explain why it is the dominant species of green tides that occur in the China's sea area of the Yellow Sea.The growth rate of floating U.prolifera was about 20%–31%d–1,which was much higher than Blidingia(Italic)sp.There were about 1.7×104 t of attached algae on the Pyropia aquaculture rafts in May 2012.We found that 39%of attached algae could float when the tide rose in the Subei Shoal,and U.prolifera accounted for 63%of the floating algae.Our analysis estimated that about 4000 t of attached U.prolifera floated into the surrounding waters of the Subei Shoal during the recycling period of aquaculture rafts.These results suggest that the initial floating biomass of large-scale green tides in the Yellow Sea is determined by the U.prolifera biomass attached to Pyropia aquaculture rafts,further impacting the scale of the green tide。

Effects of forced aeration on community dynamics of free and attached bacteria in copper sulphide ore bioleaching

Bacterial community dynamics and copper leaching with applied forced aeration were investigated during low-grade copper sulphide bioleaching to obtain better bioleaching efficiency.Results illustrated that appropriate aeration improved bacterial concentrations and leaching efficiencies.The highest bacterial concentration and Cu^(2+)concentration after 14-d leaching were 7.61×10^(7) cells·mL^(−1) and 704.9 mg·L^(−1),respectively,at aeration duration of 4 h·d^(−1).The attached bacteria played a significant role during bioleaching from 1 to 7 d.However,free bacteria dominated the bioleaching processes from 8 to 14 d.This phenomenon was mainly caused by the formation of passivation layer through Fe3+hydrolysis along with bioleaching,which inhibited the contact between the attached bacteria and ore.Meanwhile,16S rDNA analysis verified the effect of Acidithiobacillus ferrooxidans and Acidithiobacillus thiooxidans on the bioleaching process.The results demonstrate the importance of free and attached bacteria in bioleaching.

Studies on the Attached Cultivation of Filamentous Oleaginous Microalga Tribonema minus

Attached cultivation is a promising method for microalgal biomass production. Filamentous oleaginous microalga Tribonema minus(hereafter T. minus) has shown a remarkable potential for biofuel production in terms of its high lipid content. However, the strain has only been cultivated in suspended cultivation systems including open pond and closed photobioreactors. Here, we attempted to study the attached cultivation of T. minus, which might be helpful for its scale-up cultivation and industrial applications. As the results, the optimal conditions for T. minus growth in the attached biofilm are 200 μmol photons m^-2 s^-1 of light intensity and 5% of CO2, and the maximum biomass density of 223 g m^-2 has been achieved under the light intensity. The non-woven fabric as substratum was found as the best substratum in thin layer attached bioreactor, on which the average biomass productivity of T. minus is about(9.73 ± 2.19) g m^-2)d^-1. Furthermore, two attached bioreactor systems, rotary drum and rotation disc, were designed following the light dilution strategy and introduced into T. minus cultivation. The highest footprint areal biomass productivity of these two systems is 33 and 47.1 g m^-2 d^-1, respectively, much higher than that in suspended cultivation system. The results shows that T. minus can be cultured with attached cultivation method to improve its biomass productivity.

HUSTserver:Implementation for Reliable and High-Performance Network Attached Storage System

Network attached storage (NAS) with the properties of improved scalability, simplified management, low cost and balanced price performance, is desirable for high performance storage systems applied to extensive areas. Unfortunately, it also has some disadvantages such as increased network workload, and inconvenience in disaster recovery. To overcome these disadvantages, we propose a channel bonding technique and provide hot backup functions in the designed NAS system, named HUSTserver. Channel bonding means merging multiple Ethernet channels into integrated one, and that the data packets can be transferred through any available network channels in a parallel mode. The hot backup function provides automatic data mirroring among servers. In this paper, we first describe the whole system prototype from a software and hardware architecture view. Then, multiple Ethernet and hot backup technologies that distinguish HUSTserver from others are discussed in detail. The findings presented demonstrate that network bandwidth can be scaled by the use of multiple commodity networks. Dual parallel channels of commodity 100 Mbps Ethernet are both necessary and sufficient to support the data rates of multiple concurrent file transfers. And the hot backup function introduced in our system provides high data accessibility.

Preliminary Validation of Tumor Cell Attachment Inhibition Assay for Developmental Toxicants With Mouse S180 Cells

This study was designed to explore the possibility of using ascitic mouse sarcoma cell line (S180) to validate the mouse tumor cell attachment assay for developmental toxicants, and to test the inhibitory effects of various developmental toxicants. The results showed that 2 of 3 developmental toxicants under consideration, sodium pentobarbital and ethanol, significantly inhibited S180cells attachment to Concanavalin A-coaed surfaces. Inhibition was dependent on concentration, and the IC50 (the concentration tha reduced attachment by 50% ), of these 2 chemicals was 1.2×10-3mol/L and 1 .0 mol/L, respectively. Anoher developmental toxiant, hydmiortisone, did not show inhibitory activity. Two non-developmental toxicants, sodium chloride and glycine were also tested and these did not decrease attachment rates. The main results reported here were generally sindlar to those obtained with ascitic mouse ovdrian tumor cells as a model. Therefore, this study added further evidence to the conclusion that cell specificity does not lindt attachment inhibition to Con A-coated surfaces, so S180 cell may serve as an altemative cell model, especially when other cell lines are unavailable. Furthermore, after optimal validation, it can be suggested that an S180 cell attachment assay may be a candidate for a series of assays to detect developmental toxicants.

Adaptive Wall-Based Attachment Ventilation:A Comparative Study on Its Effectiveness in Airborne Infection Isolation Rooms with Negative Pressure

The transmission of coronavirus disease 2019(COVID-19)has presented challenges for the control of the indoor environment of isolation wards.Scientific air distribution design and operation management are crucial to ensure the environmental safety of medical staff.This paper proposes the application of adaptive wall-based attachment ventilation and evaluates this air supply mode based on contaminants dispersion,removal efficiency,thermal comfort,and operating expense.Adaptive wall-based attachment ventilation provides a direct supply of fresh air to the occupied zone.In comparison with a ceiling air supply or upper sidewall air supply,adaptive wall-based attachment ventilation results in a 15%–47%lower average concentration of contaminants,for a continual release of contaminants at the same air changes per hour(ACH;10 h^(-1)).The contaminant removal efficiency of complete mixing ventilation cannot exceed 1.For adaptive wall-based attachment ventilation,the contaminant removal efficiency is an exponential function of the ACH.Compared with the ceiling air supply mode or upper sidewall air supply mode,adaptive wall-based attachment ventilation achieves a similar thermal comfort level(predicted mean vote(PMV)of0.1–0.4;draught rate of 2.5%–6.7%)and a similar performance in removing contaminants,but has a lower ACH and uses less energy.