Background: Although a number of studies have reported that the hot and humid compress from traditional Chinese medicine (TCM) is effective in treating lumbar disc herniation (LDH) with qi stagnation and blood stasis,...Background: Although a number of studies have reported that the hot and humid compress from traditional Chinese medicine (TCM) is effective in treating lumbar disc herniation (LDH) with qi stagnation and blood stasis, clinical evidence is limited. Objective: The purpose of this study is to provide high-quality evidence to support the effectiveness of the traditional Chinese hot and humid compress in the treatment of LDH with qi stagnation and blood stasis. Methods: From October 2021 to November 2023, 86 patients with LDH of qi stagnation and blood stasis type were recruited in our hospital and divided into a control (n = 43) and an observation group (n = 43) according to the random number table method. The control group was given routine clinical treatment, and the observation group was treated with the hot and humid compress therapy for two weeks. The visual analogue scale (VAS) score, Japanese Orthopaedic Association (JOA) score, TCM syndrome score, serum interleukin-6 (IL-6), serum interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were observed and compared between the two groups before and after treatment, and the clinical efficacy of the two groups was evaluated. Results: After treatment, the VAS score, TCM symptom score, and serum IL-6, IL-1β, and TNF-α levels decreased in both groups (P P P P P Conclusions: The hot and humid compress of traditional Chinese medicine can effectively relieve pain, restore lumbar function, improve TCM syndromes, reduce the level of inflammatory factors, and have a curative effect in treating LDH.展开更多
目的:探讨谷红注射液联合中药热敷治疗卒中后认知障碍的临床效果。方法:前瞻性选取2020年8月—2022年8月无锡市康复医院收治的88例卒中后认知障碍患者。根据抽签法将其分为研究组和对照组,各44例。两组均给予常规治疗,对照组给予谷红注...目的:探讨谷红注射液联合中药热敷治疗卒中后认知障碍的临床效果。方法:前瞻性选取2020年8月—2022年8月无锡市康复医院收治的88例卒中后认知障碍患者。根据抽签法将其分为研究组和对照组,各44例。两组均给予常规治疗,对照组给予谷红注射液,研究组在对照组基础上给予中药热敷。比较两组治疗后临床效果、治疗前后神经功能、认知功能、血清学指标、脑血流动力学。结果:研究组总有效率为95.45%,显著高于对照组的79.55%,差异有统计学意义(P<0.05)。治疗后,研究组蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、简易智能精神状态检查量表(mini-mental state examination,MMSE)评分均高于对照组,美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分明显低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组S-100钙结合蛋白β(S-100 calcium binding protein β,S-100β)、视锥蛋白样蛋白-l(visinin like protein 1,VILIP-1)水平均低于对照组,胰岛素样生长因子1(insulin-like growth factor 1,IGF-1)水平高于对照组,差异有统计学意义(P<0.05)。治疗后,研究组收缩期峰值流速(peak flow velocity of systole,Vp)、平均血流速度(mean velocity,Vm)均高于对照组,搏动指数(pulse index,PI)低于对照组,差异有统计学意义(P<0.05)。结论:谷红注射液联合中药热敷治疗卒中后认知障碍患者能促进神经功能恢复,改善认知功能,改善脑血流动力学,提高治疗效果。展开更多
文摘Background: Although a number of studies have reported that the hot and humid compress from traditional Chinese medicine (TCM) is effective in treating lumbar disc herniation (LDH) with qi stagnation and blood stasis, clinical evidence is limited. Objective: The purpose of this study is to provide high-quality evidence to support the effectiveness of the traditional Chinese hot and humid compress in the treatment of LDH with qi stagnation and blood stasis. Methods: From October 2021 to November 2023, 86 patients with LDH of qi stagnation and blood stasis type were recruited in our hospital and divided into a control (n = 43) and an observation group (n = 43) according to the random number table method. The control group was given routine clinical treatment, and the observation group was treated with the hot and humid compress therapy for two weeks. The visual analogue scale (VAS) score, Japanese Orthopaedic Association (JOA) score, TCM syndrome score, serum interleukin-6 (IL-6), serum interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were observed and compared between the two groups before and after treatment, and the clinical efficacy of the two groups was evaluated. Results: After treatment, the VAS score, TCM symptom score, and serum IL-6, IL-1β, and TNF-α levels decreased in both groups (P P P P P Conclusions: The hot and humid compress of traditional Chinese medicine can effectively relieve pain, restore lumbar function, improve TCM syndromes, reduce the level of inflammatory factors, and have a curative effect in treating LDH.
文摘目的:探讨谷红注射液联合中药热敷治疗卒中后认知障碍的临床效果。方法:前瞻性选取2020年8月—2022年8月无锡市康复医院收治的88例卒中后认知障碍患者。根据抽签法将其分为研究组和对照组,各44例。两组均给予常规治疗,对照组给予谷红注射液,研究组在对照组基础上给予中药热敷。比较两组治疗后临床效果、治疗前后神经功能、认知功能、血清学指标、脑血流动力学。结果:研究组总有效率为95.45%,显著高于对照组的79.55%,差异有统计学意义(P<0.05)。治疗后,研究组蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)、简易智能精神状态检查量表(mini-mental state examination,MMSE)评分均高于对照组,美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分明显低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组S-100钙结合蛋白β(S-100 calcium binding protein β,S-100β)、视锥蛋白样蛋白-l(visinin like protein 1,VILIP-1)水平均低于对照组,胰岛素样生长因子1(insulin-like growth factor 1,IGF-1)水平高于对照组,差异有统计学意义(P<0.05)。治疗后,研究组收缩期峰值流速(peak flow velocity of systole,Vp)、平均血流速度(mean velocity,Vm)均高于对照组,搏动指数(pulse index,PI)低于对照组,差异有统计学意义(P<0.05)。结论:谷红注射液联合中药热敷治疗卒中后认知障碍患者能促进神经功能恢复,改善认知功能,改善脑血流动力学,提高治疗效果。
