An Analysis of Health Factors Affecting Employees’ Absenteeism: Influences of HDL Cholesterol and Blood Sugar Levels

Background: Workers’ health condition is an important issue. It affects not only the well-being of workers but also the firms and society as a whole through medical costs and productivity losses due to absenteeism and presenteeism. Data and Methods: Data were obtained from 1136 employees at an operational site of a large corporation. The dataset contained both medical checkups and working record information. Health factors affecting long-term absence (over three days in three months) were analyzed. Logistic regression models and the procedure for selecting proper covariates based on likelihood test statistics and the Akaike information criterion were used. Results: Among health factors, high-density lipoprotein cholesterol (HDL-C) and blood sugar levels were important in the selected model. For HDL-C, the odds ratio (OR) based on one standard deviation difference was 0.75 with a 95% confidence interval (CI) of 0.59 - 0.95. For blood sugar, the OR was 1.20 with a 95% CI of 1.01 - 1.42. Improving HDL-C and blood sugar levels would reduce long-term absence by 25% and 20%, respectively. Conclusion: Controlling HDL-C and blood sugar levels is important to reduce long-term absenteeism. These factors can be improved by modifying eating habits. Since the operational site has its own company cafeterias, which most employees use, nutritional intervention is relatively easy with little or no cost. It may be worthwhile to implement nutritional intervention, especially for patients with low HDL-C or high blood sugar levels. Limitations: The results of this study were based on one operational site of a corporation. The employees were mainly operators working inside the building. The results may be different from other types of jobs and working conditions, such as fieldwork. Analyses of different types of jobs and working conditions are necessary.

Factors associated with patient absenteeism for scheduled endoscopy

AIM: To identify risk factors to help predict which patients are likely to fail to appear for an endoscopic procedure. METHODS: This was a retrospective, chart review, cohort study in a Canadian, tertiary care, academic, hospital-based endoscopy clinic. Patients included were: those undergoing esophagogastroduodenoscopy, colonoscopy or flexible sigmoidoscopy and patients who failed to appear were compared to a control group. The main outcome measure was a multivariate analysis of factors associated with truancy from scheduled endoscopic procedures. Factors analyzed included gender, age, waiting time, type of procedure, referring physician, distance to hospital, first or subsequent endoscopic procedure or encounter with gastroenterologist, and urgency of the procedure. RESULTS: Two hundred and thirty-four patients did not show up for their scheduled appointment. Compared to a control group, factors statistically significantly associated with truancy in the multivariate analysis were: non-urgent vs urgent procedure (OR 1.62, 95% CI 1.06, 2.450), referred by a specialist vs a family doctor (OR 2.76, 95% CI 1.31, 5.52) and office-based consult prior to endoscopy vs consult and endoscopic procedure during the same appointment (OR 2.24, 95% CI 1.33, 3.78). CONCLUSION: Identifying patients who are not scheduled for same-day consult and endoscopy, those referred by a specialist, and those with non-urgent referrals may help reduce patient truancy.

Performance analysis of surface plasmon resonance sensor with high-order absentee layer

A surface plasmon resonance （SPR） sensor with a high-order absentee layer on the top of metallic film is proposed. The performance of the SPR sensor with NaCl, MgO, TiO2 or AlAs high-order absentee layer is analyzed theoretically. The results indicate that the sensitivity and the full width at half maximum of those SPR sensors decrease with the increasing of the order of absentee layer, but the variation of the figure of merit （FOM） depends on the refractive index of absentee layer. By improving the order of absentee layer with high-refractive-index, the FOM of the SPR sensor can be enhanced. The maximum value of FOM for the SPR sensor with high-order TiO2 （or AlAs） absentee layer is 1.059% （or 2.587%） higher than the one with one-order absentee layer. It is believed the proposed SPR sensor with high-order absentee layer will be helpful for developing the high-performance SPR sensors.

Impact of Metabolic-Syndrome Risk Factors on the Absenteeism of Health Workers from a Brazilian University Hospital

Objective: Analyzing the association between Metabolic Syndrome (MS) risk factors and work absenteeism due to illnesses among University Hospital employees in Salvador City, Bahia, Brazil. Methods: Cross-sectional study comprised 1173 Bahia Federal University Hospital employees: 57.3% of them were federal employees (statutory officers) and 42.7% were civil servants (CLT employees). Participants were in the age group 41.5 years: 69.4% were female and 30.6% were male. Results: MS prevalence in employees reached 6.6%;women accounted for 69.7% of the total. The percentage increases with age and has similar proportion among directcare providers and ancillary supports personnel, 40.8% and 39.5%, respectively. The risk factor analysis showed 25% hypertension, 54.6% weight excess (18.4% obese and 36.2% overweight patients), 20% hypercholesterolemia, 9.9% hypertriglyceridemia and 6.5% diabetes mellitus prevalence. Absenteeism longer than one day within the studied population reached 40.1%. Osteoarticular diseases were the most common reason for absenteeism, accounting for 50.7% of it: 62.6% of whom were either overweight or obese. The mean cost with absenteeism per employee was R$5492.87 ($2347.00 US Dollars), and it corresponds to annual cost of R 2,587,139.53 ($1,105,610.00 US Dollars). The highest cost with absenteeism caused by illnesses was recorded for female workers;for federal employees who were patient caregivers, who worked in the Pediatric Centre and who worked at night shifts. Conclusion: The high Metabolic Syndrome risk factors and overweight incidence are responsible for the increased costs faced by hospitals due to high absenteeism rates.

Descriptive Epidemiology for <i>Mycoplasma pneumoniae</i>Infection Using (Nursery) School Absenteeism Surveillance System, and Proposal for Countermeasures

Objective: We present descriptive epidemiology of Mycoplasma infection using the (Nursery) School Absenteeism Surveillance System ((N)SASSy) in addition to national official sentinel surveillance for infectious diseases (NOSSID). It is expected to be helpful for early detection and response to outbreak of Mycoplasma infection and also to be useful for antimicrobial resistance measures. Method: The study period was 2010-2014 seasons. The study area was the whole of Ibaraki prefecture, Japan. NOSSID reports the number of patients with Mycoplasma pneumonia from 13 sentinel hospitals. We compare the number of patients and the incidence rate of NOSSID with the same information in (N)SASSy. Result: In NOSSID, the largest number of patients by age was 27 patients of one year old in 2012. (N)SASSy showed that the incidence rate in the elementary schools is high in 2011 and 2012. Especially, the second grade students were the highest. Discussion: Even though Mycoplasma infection is well known as a pediatric disease, we showed that second grade was the highest in incidence at first. Because (N)SASSy is timely and real-time information collection, evaluation and sharing countermeasures with (nursery) schools, public health centers, and physicians are useful for students and nursery school children, and communities. Conclusion: Because mycoplasma infection is common pediatric infectious diseases and because some patients rarely develop severe infections, we must prevent larger outbreaks. (N)SASSy can provide timely intervention at the initial phase of outbreak by monitoring situations in (nursery) schools and comparing data to baseline information.

Extensive Medical Absenteeism among Secondary School Students: An Observational Study on Their Health Condition from a Biopsychosocial Perspective

An adequate approach to reducing school absenteeism should focus on medical absenteeism as this is the most prevalent form of school absenteeism. The objective of this study is to explore the health condition of pre-vocational secondary students with extensive medical absenteeism from a biopsychosocial perspective. Data were obtained from medical assessments and Strengths and Difficulties Questionnaires (SDQs) of students with medical absence above threshold criteria (i.e. reported sick four times in 12 school weeks or more than six consecutive school days) who were referred to a youth health care physician. The results showed that the students had a mean absence rate of 14% in 12 school weeks. Of all students, 43.5% had a diagnosed disease and 81.5% had problems such as physical complaints not yet diagnosed, psychosocial problems, lifestyle problems and sleeping difficulties. Four groups could be distinguished: 13.4% with a diagnosed disease and no problem, 30.1% with a diagnosed disease and a problem, 51.5% with a problem and no diagnosed disease and 5.1% without a diagnosed disease or problem. Significantly higher scores of the Total difficulties-scale on the SDQ were found (mean 10.5;SD 5.8) in the study group, compared to a reference group (mean 9.1;SD 4.9). In conclusion, this study shows that when using the aforementioned criteria for extensive medical absenteeism to intervene with the absence, students with a mean absence rate of 14% in 12 school weeks are identified. If there was a diagnosed disease, it was accompanied by problems about twice as often. More than half of the students’ absence was caused by problems rather than a disease. The great diversity of these problems calls for a personalized approach. A broad perspective, including medical expertise, is needed to distinguish between emerging mental and physical diseases, psychosocial and lifestyle problems.

The Risk and Protective Factors of School Absenteeism

Absenteeism from school in children and adolescents is a problem that impacts the social, emotional and educational development of the children (Haarman, 2011). While absenteeism can be seen as a short-term condition, prolonged absenteeism during childhood may be a predictor of lasting issues that may persist into adulthood (King, Ollendick and Tonge, 1995), such as “school dropout, delinquency and occupational and relationship problems” (Kearney and Bensaheb,?2006), and economic deprivation and social, marital, occupational and psychiatric problems (Kearney and Graczyk, 2014). Early absenteeism has been associated with school dropout, further?disconnecting the children from school based health programs and leading the children into economic deprivation, and marital, social and psychiatric problems in adulthood (Kogan, Luo, Murry and Brody, 2005). Furthermore, absenteeism may be an indication of “suicide attempt, perilous sexual behaviour, teenage pregnancy, violence, unintentional injury, driving under the influence of alcohol, and alcohol, marijuana, tobacco, and other substance abuse” (Kearney, 2008). The purpose of this article is to provide a review of the literature on protective and risk factors for school absenteeism in youths aged 5 to 18 years old, with focus on articles published after 2004. First, the definition of absenteeism will be discussed, followed by the prevalence and demographic of this phenomenon, the protective and risk factors of school absenteeism, and a review of intervention strategies.

Staff Absenteeism in Public Health Facilities of Uganda: A Study in Bushenyi District on Contributing Factors

Background: Staff absenteeism is a global challenge in health care service delivery that has not spared any country. Aim: This was to assess the factors contributing to staff absenteeism in public health facilities in Bushenyi District of Uganda. Method: This was a cross sectional study conducted for a period of 3 months in which data were collected using a questionnaire and interviews. Results: Majority of participants were females (66.4%) which 50% in the age of 31 - 45 years. The study showed that residing outside the health facility (42.1%) i.e. walking distances over 10 km to get to work was a challenge. Family conflicts, overstay in one workstation without rotations to other major health facilities and drug abuse as well as inadequate supervision were major contributing factors to absenteeism (P Conclusion: Staff absenteeism in rural communities is a major challenge that needs a multi-sectorial approach for its effective management, thus showing a need to revise policy in the health sector.

Prevalence of Menstrual Pain among Saudi Nursing Students and Its Effect on Sickness Absenteeism

Background: Primary menstrual pain is a well-known gynecological disorder among adult females including nursing undergraduate students. Nursing students tend not to seek medical treatment. As a result, this affects their quality of academic life and also absenteeism rate is increased. Objectives: To evaluate the prevalence of menstrual pain and its effect on sickness absenteeism on nursing student. Methods: This is a descriptive survey research design study by means of using a validated and modified questionnaire. Questionnaire information regarding menstrual pain severity, history and absenteeism were included. The research took place in the collage of nursing at the largest University in the world, Princess Nourah Bint Abdelrahman University, Riyadh, Saudi Arabia. A total of 100 single, female, unmarried undergraduate nursing students (Year 1, 2, 3, 4) were recruited by personal invitation during lectures. Result: The prevalence of menstrual pain was 92%. Most of the nursing students 27% had menstrual pain of moderate grade 5 - 6 and 38% of nursing students did not take pain medication for it. Lecture and collage absenteeism due to menstrual pain was present in 9% and 30% respectively. Finally, there was no significant correlation between menstrual pain and age of menarche, age and height. Conclusion: Menstrual pain is widely common prevalent among nursing undergraduates. As a result, it affects the quality of students’ day-to-day life routine. The majority of nursing students’ rarely seeks medical treatment. Providing health and patient education to improve awareness on managing menstrual period might help in avoiding students’ absence from classes.

Analysis of Measured Employees’ Absenteeism in the Forensic Science Laboratory

A detailed analysis of the measured absenteeism data for employees in a forensic science laboratory (FSL) is presented. About 134 employees out of 172 were used as a sample. The factors assumed to affect absenteeism included differences in gender, departments/units, period of the year, skill-levels and professions. The data were collected throughout a calendar year, using a biometric system infrastructure incorporating fingerprint capturing device, IP camera, database server and software (Bio Star Version 1.62). The calendar was used to establish the total working days and hours while employee absenteeism data in percentage were established by computation of days and hours absent for a given period, based on days or hours attended. Equations were derived to determine the absenteeism ratios expressed in percentage (Abd and Abh). The absenteeism ratio, Abh, was observed to be the most appropriate parameter. The business development department (BDD) shows the lowest Abh compared to other departments. Female employees show higher Abh and lower Abd than male employees, while accountants show lowest absenteeism compared to Employees in professional level who had highest absence rate compared to skilled, semi-skilled and unskilled employees. Most hours were lost during September-December compared to the rest of the year. The results reveal higher employee absenteeism in the FSL affecting its performance.

Effect of hand hygiene intervention on the absenteeism of pre-school children in Klang Valley,Malaysia:a quasi-experimental study

Background Absenteeism amongst pre-school children is often due to illnesses such as hand,foot,and mouth disease,acute gastroenteritis,cold and flu,which are easily spread amongst them.This is because of weak immunity and lack of knowledge on proper hand hygiene.This quasi-experimental study assessed the efficacy of an intervention consisting of a hand hygiene education programme,along with digital tools in bringing about a change in behaviour and health conditions amongst pre-school children in Klang Valley,Malaysia.Methods A total of 377 school children,male and female,aged 5–6 years old,participated and were assigned to either the intervention or a control group.During the 2 months intervention period,children in the test group were trained on proper hand hygiene practices and techniques with the aid of the interactive android-based tablets.The numbers of absent days of all the children were recorded for 2 months before the intervention and during the intervention.Results In the test group,there was a 25%increase in the total number of absent days from the pre-intervention period to the intervention period,a much lesser increment observed as compared to that of control group in which the increase was much higher at 89%.Results showed a significant difference(P<0·05)between the absenteeism rates for the test and control group during the intervention period.Conclusion These results suggest that proper education and intervention increase hand hygiene compliance,which may help decrease school absenteeism due to illness;however,a longer study duration may be necessary to evaluate the benefit further.

Enhanced Public Health Surveillance for the Sixth Worldwide Uchinanchu Festival Conducted by the Okinawa Prefectural Government, Japan

Objective: The Okinawa prefectural government conducted enhanced surveillance for the Sixth Worldwide Uchinanchu Festival, with participation of more than 5300 visitors from abroad, many of whom were Okinawan or of Okinawan descent, for early detection of Zika virus disease and other potential public health threat outbreaks. Method: Enhanced surveillance conducted from 12 October through 13 November involved four surveillance systems, (Nursery) School Absenteeism Surveillance system ((N)SASSy), Prescription Surveillance (PS), and Official Syndromic Surveillance (OSS), each of them operates routinely, in addition to case-based and sentinel surveillance under the Infectious Diseases Control Law as Official National Surveillance of Infectious Diseases (ONSID). This enhanced surveillance was conducted for analysis and evaluation, with intensive information sharing among concerned parties. Result: We performed the enhanced surveillance for 33 days from 12 October through 13 November. Information from enhanced surveillance was analyzed and evaluated, and eventually summarized as a daily report. There has been one rubella case at an elementary school in Okinawa City on 20 October and a measles case at an elementary school in Uruma City on 2 November. Those two cases were registered into (N)SASSy on a timely basis. The public health center investigated them quickly, and the measles case was denied later because symptoms did not satisfy with case definition. Discussion: We regard enhanced surveillance as useful to confirm events that might demand a public health response. Moreover, the related including public health centers or medical institutions confirmed the situation as valuable for the administrative structure. However, because almost all (nursery) schools or pharmacies are closed during successive holidays, outbreaks that occur on such days cannot be recognized on a timely basis. More sensitive surveillance for such days, with better preparations for ambulance transfer and at emergency departments in hospitals remains as a challenge for future work.

Effects of AIDS-related disability on workforce participation and earned income in Botswana: A quasi-experimental evaluation

Background: Botswana is regarded as a leader of progressive HIV/AIDS policy, as the first country in sub-Saharan Africa to establish a free, national antiretroviral therapy program. In light of such programmatic successes, it is important to evaluate the potentially changing relationship of HIV/AIDS to the wellbeing of individuals, households, and institutions in the country. Methods: We evaluate the effects of HIV-related illness on absenteeism and earnings several years after the start of the national treatment program among a random sample of adults in Botswana using survey data from 3999 individuals aged 15 to 49, using quasi-experimental methods. We compare absenteeism between individuals with and without HIV-related illness, using a propensity score matching approach. We then estimate the effect of HIV-related illness on earnings using a Heckman selection model to account for selection into the workforce. We stratify our analyses by sex. Results: Men and women with HIV-related illness were absent by about 5.2 and 3.3 additional days, respectively, in the month prior to the survey compared to matched controls, and earned approximately 38% and 43% less, respectively, in the month prior to the survey compared to those without HIV-related illness. Conclusions: HIV-related illness appears to increase absenteeism in this sample and dramatically reduce earnings. The findings suggest a need for policies that confer greater financial security to individuals with HIV/AIDS in Botswana.

Investigation of Prefrontal Cortex Activity in University Students with Presenteeism: A Near-Infrared Spectroscopy (NIRS) Study

Presenteeism refers to impaired performance attributed to attending work with health problems. There has been no study examining the state of presenteeism with objective measures. We compared cerebral hemodynamic changes, measured by near-infrared spectroscopy (NIRS), during neuropsychological tests conducted by university students with presenteeism and healthy controls. Twenty-two university students participated in the study;11 of them with impaired performance caused by mental health problem were allocated to the presenteeism group and 11 without health problems to the control group. Presenteeism was assessed by the Presenteeism Scale for Students. To evoke hemodynamics changes, the participants completed a Word Fluency Test (WFT) and a Trail Making Test (TMT). The NIRS probes were located over the bilateral prefrontal area. Students with presenteeism had significantly higher incidences of depression than controls. However, there was no significant difference in behavioral performance examinations between the two groups. With regard to hemodynamics changes, the repeated measures analysis of covariance of the NIRS signals revealed significant interactions between group and task activation. Although we observed a significant increase in oxygenated hemoglobin concentration during the WFT among controls (simple main effect;left channel, F(1, 19) = 27.34, P F(1, 19) = 22.05, P < 0.001), no changes were found in students with presenteeism during either the WFT (simple main effect;left channel, F(1, 19) = 0.12, P F(1, 19) = 0.08, P t = ﹣0.94, P with Bonferroni correction = 0.745;right channel, t = ﹣2.19, P with Bonferroni correction < 0.113). This is the first study to reveal differences in activity in the cerebral cortex associated with presenteeism. The fact that students with presenteeism have prefrontal dysfunction might reinforce the concept of presenteeism.

Outbreak of Human Metapneumovirus in Ibaraki, Japan and Its Descriptive Epidemiology

Introduction: The Infection Control Law in Japan does not cover monitoring of human metapneumovirus (HMPV). Therefore, its epidemiology is not well known. However, rapid diagnostic testing for this virus has been reimbursed by public health insurance in Japan since 2014. One case of acute encephalitis caused by HMPV was reported in April 2017 in Ibaraki. All schools in Ibaraki prefecture started to participate in the (Nursery) School Absenteeism Surveillance System ((N)SASSy) in 2009. All nursery schools started to use it in 2012. Methods: We specifically examine its seasonality and incidence by age. The study period extends from October 1, 2014 through May 31, 2017. Results: In total, (N)SASSy received 187 cases during the period. Spring and early summer were apparently the high season. The highest incidence was 36 cases in April 2015. The incidence among zero and one year olds was higher in 2017 than in the same season among 2014-2016. The necessary effort to download data from (N)SASSy, show these figures, and confirm the situation and background was a few minutes. Discussion: Rapid diagnostic testing for HMPV elucidated its epidemiology for the first time. Moreover, timely information sharing through (N)SASSy led the Ibaraki prefectural office to publish a reminder in July 2017 about the HMPV outbreak situation and to encourage precautions against it by nursery schools.

Outbreak Information Delivery to Families with (Pre)School Children and Its Contribution

Background: Infection transmission among them occurs easily and sometimes causes outbreaks at facilities where children live in groups. Early response is necessary for infection control measures to avoid larger clusters. In Japan, (Nursery) School Absenteeism Surveillance System ((N)SASSy), which is a kind of school absenteeism surveillance, has activated since 2007 and covers about 60% of all schools and 40% of all nursery schools in 2017. Objective: The objective of the present paper is investigation and demonstration of how caregivers receive information related to infectious diseases in Japan and how (N)SASSy contributes health of children. Method: We randomly selected subjects with children by pre-fecture in October, 2017. The survey questionnaire asked background information and information about infectious diseases to maintain health in children. We regressed health concern variables on background information and information provision situation about community outbreaks using weighted logistic regression. Results: We received responses from 1172 people. Estimation results showed higher concern about a facility providing information about community outbreak. Caregivers whose children attend facilities provided about community outbreak or covered (N)SASSy significantly higher opportunity to arrange a schedule when a child has a high fever. Discussion: The obtained results demonstrated that activation in (N)SASSy affects the possibility of arranging a schedule when a child has a high fever. This capability might improve community health.

Enhanced Surveillance for National (Handicapped) Sports Games in Wakayama, Japan 2015

Introduction: We undertook enhanced surveillance of the 2015 Kinokuni Wakayama National Sports Games (70th National Sports Games) and the Kinokuni Wakayama Handicapped Sports Games (15th National Handicapped Sports Games) held in Wakayama prefecture in 2015, for which this paper presented operational details and an evaluation. Methods: Enhanced surveillance conducted involved (Nursery) School Absenteeism Surveillance system ((N)SASSy), Prescription Surveillance, and Ambulance Transfer Surveillance from 30 August through 9 November. We evaluated those surveillances on all days including weekends, integrated the results as a daily report, and published it on the web. Results: We found no cluster or cases requiring more tracing and investigation except for suspected cases of rubella in (N)SASSy. Moreover, no moderate aberration was found for two consecutive days for the same area and symptom. Conclusion: Our experience with this enhanced surveillance presents important lessons for countermeasures by local governments for mass gatherings or politically important events.

Work Productivity and Activity Impairment in Colorectal Cancer Patients Treated with Capecitabine

Background: The employment status of workers with cancer has important implications for impairment of intimate and family relationships and for economic, social and psychological health. The aim of the present study was to evaluate the effect of chemotherapy with capecitabine in patients with colorectal cancer on work productivity and daily activity. Methods: 30 patients with primary diagnosis of stage III colorectal cancer were enrolled for our study. All patients received capecitabine twice daily at a cumulative dose of 2500 mg/m2 on days 1 -14 and repeated on day 22. Work productivity was determined using the WPAI questionnaire. Results: We observed a significant increase in absenteeism after 1 cycle, after 6 cycles of therapy and at follow-up (p 0.001). On the other hand, presenteeism, work productivity loss and daily activity impairment, increased after 1 cycle and 6 cycles of therapy, but we could not find statistically different significances. Conclusions: Colorectal cancer diagnosis and treatment are associated with frailty and vulnerability. Chemotherapy with capecitabine may result in negative consequences for job performance.

The Role of Work in Breast Cancer Patients

Background: Since the survival rates of cancer have increased considerably, the long-term side effects of cancer and cancer-related treatments may impact survivors’ capability to regain normal lives. The aim of this study was to evaluate the effects of the breast cancer on the job satisfaction and the quality of life. Methods: We enrolled 130 women divided into four groups: 1) 40 breast cancer survivors (aged 39 - 50);2) 44 women diagnosed with breast cancer (aged 35 - 49);3) 46 women in good health status (aged 37 - 48). Job satisfaction was measured with the Warr-Cook-Wall (WCW) Job satisfaction scale that measures overall job satisfaction and satisfaction with nine aspects of work. Results: Compared to healthy subjects, breast cancer survivors reported a poorer number of hours of work (p < 0.05) and a significant amount of variety in job (p < 0.01), opportunity to use abilities (p < 0.001), income (p < 0.01). Compared to patients with breast cancer at diagnosis, breast cancer survivors reported a significant amount of variety in job (p < 0.05), opportunity to use abilities (p < 0.05), amount of responsibility (p < 0.05), income (p < 0.05). In our study, the comparison between breast cancer survivors, breast cancer at diagnosis, and healthy subjects does not differ significantly in overall job satisfaction. Conclusions: Understanding the job problems associated with cancer can provide relevant information regarding potential treatment and psychological support in breast cancer survivors.

Work Productivity and Activity Impairment in Breast Cancer Patients Treated with Capecitabine

Background: Although the majority of breast cancer patients are able to work, lower work ability and reduced job retention have been reported. The aim of the present study was to evaluate the effect of chemotherapy with capecitabine in patients with breast cancer on work productivity and daily activity. Methods: 34 patients with metastatic breast cancer were enrolled for our study. Capecitabine was given twice daily at a cumulative dose of 2500 mg/m2 on days 1 - 14 and repeated on day 22. Work productivity was determined using the WPAI questionnaire. Results: We observed an increase in absenteeism, presenteeism, work productivity loss and daily activity impairment after 1 cycle and 6 cycles of therapy, but we could not find statistically different significances. Conclusions: This study provides some data indicating an association between problems in breast cancer and work. Our results confirm that capecitabine may improve quality of life of patients with metastatic breast cancer.