Massive computational complexity and memory requirement of artificial intelligence models impede their deploy-ability on edge computing devices of the Internet of Things(IoT).While Power-of-Two(PoT)quantization is pro...Massive computational complexity and memory requirement of artificial intelligence models impede their deploy-ability on edge computing devices of the Internet of Things(IoT).While Power-of-Two(PoT)quantization is pro-posed to improve the efficiency for edge inference of Deep Neural Networks(DNNs),existing PoT schemes require a huge amount of bit-wise manipulation and have large memory overhead,and their efficiency is bounded by the bottleneck of computation latency and memory footprint.To tackle this challenge,we present an efficient inference approach on the basis of PoT quantization and model compression.An integer-only scalar PoT quantization(IOS-PoT)is designed jointly with a distribution loss regularizer,wherein the regularizer minimizes quantization errors and training disturbances.Additionally,two-stage model compression is developed to effectively reduce memory requirement,and alleviate bandwidth usage in communications of networked heterogenous learning systems.The product look-up table(P-LUT)inference scheme is leveraged to replace bit-shifting with only indexing and addition operations for achieving low-latency computation and implementing efficient edge accelerators.Finally,comprehensive experiments on Residual Networks(ResNets)and efficient architectures with Canadian Institute for Advanced Research(CIFAR),ImageNet,and Real-world Affective Faces Database(RAF-DB)datasets,indicate that our approach achieves 2×∼10×improvement in the reduction of both weight size and computation cost in comparison to state-of-the-art methods.A P-LUT accelerator prototype is implemented on the Xilinx KV260 Field Programmable Gate Array(FPGA)platform for accelerating convolution operations,with performance results showing that P-LUT reduces memory footprint by 1.45×,achieves more than 3×power efficiency and 2×resource efficiency,compared to the conventional bit-shifting scheme.展开更多
Storm surge is often the marine disaster that poses the greatest threat to life and property in coastal areas.Accurate and timely issuance of storm surge warnings to take appropriate countermeasures is an important me...Storm surge is often the marine disaster that poses the greatest threat to life and property in coastal areas.Accurate and timely issuance of storm surge warnings to take appropriate countermeasures is an important means to reduce storm surge-related losses.Storm surge numerical models are important for storm surge forecasting.To further improve the performance of the storm surge forecast models,we developed a numerical storm surge forecast model based on an unstructured spherical centroidal Voronoi tessellation(SCVT)grid.The model is based on shallow water equations in vector-invariant form,and is discretized by Arakawa C grid.The SCVT grid can not only better describe the coastline information but also avoid rigid transitions,and it has a better global consistency by generating high-resolution grids in the key areas through transition refinement.In addition,the simulation speed of the model is accelerated by using the openACC-based GPU acceleration technology to meet the timeliness requirements of operational ensemble forecast.It only takes 37 s to simulate a day in the coastal waters of China.The newly developed storm surge model was applied to simulate typhoon-induced storm surges in the coastal waters of China.The hindcast experiments on the selected representative typhoon-induced storm surge processes indicate that the model can reasonably simulate the distribution characteristics of storm surges.The simulated maximum storm surges and their occurrence times are consistent with the observed data at the representative tide gauge stations,and the mean absolute errors are 3.5 cm and 0.6 h respectively,showing high accuracy and application prospects.展开更多
Dependent competing risks model is a practical model in the analysis of lifetime and failure modes.The dependence can be captured using a statistical tool to explore the re-lationship among failure causes.In this pape...Dependent competing risks model is a practical model in the analysis of lifetime and failure modes.The dependence can be captured using a statistical tool to explore the re-lationship among failure causes.In this paper,an Archimedean copula is chosen to describe the dependence in a constant-stress accelerated life test.We study the Archimedean copula based dependent competing risks model using parametric and nonparametric methods.The parametric likelihood inference is presented by deriving the general expression of likelihood function based on assumed survival Archimedean copula associated with the model parameter estimation.Combining the nonparametric estimation with progressive censoring and the non-parametric copula estimation,we introduce a nonparametric reliability estimation method given competing risks data.A simulation study and a real data analysis are conducted to show the performance of the estimation methods.展开更多
The China Fusion Engineering Test Reactor plans to build a 200 k V/25 A acceleration grid power supply(AGPS)for the negative-ion-based neutral beam injector prototype system.The AGPS uses a rectifier-inverter-isolated...The China Fusion Engineering Test Reactor plans to build a 200 k V/25 A acceleration grid power supply(AGPS)for the negative-ion-based neutral beam injector prototype system.The AGPS uses a rectifier-inverter-isolated step-up structure.There is a DC bus between the rectifier and the inverter.In order to limit DC bus voltage ripple and transient fluctuations,a large number of capacitors are used,which degrades the reliability of the power supply and occupies a large amount of space.This work finds that due to the difference in the turn-off time of the rectifier and the inverter,the capacitance mainly depends on the rectifier current when the inverter is turned off.On this basis,an active power filter(APF)scheme is proposed to absorb the current.To enhance the dynamic response ability of the APF,model predictive control is adopted.In this paper,the circuit structure of the APF is introduced,the prediction model is deduced,the corresponding control strategy and signal detection method are proposed,and the simulation and experimental results show that APF can track the transient current of the DC bus and reduce the voltage fluctuation significantly.展开更多
The optimum design of equivalent accelerated life testing plan based on proportional hazards-proportional odds model using D-optimality is presented. The defined equivalent test plan is the test plan that has the same...The optimum design of equivalent accelerated life testing plan based on proportional hazards-proportional odds model using D-optimality is presented. The defined equivalent test plan is the test plan that has the same value of the determinant of Fisher information matrix. The equivalent test plan of step stress accelerated life testing (SSALT) to a baseline optimum constant stress accelerated life testing (CSALT) plan is obtained by adjusting the censoring time of SSALT and solving the optimization problem for each case to achieve the same value of the determinant of Fisher information matrix as in the baseline optimum CSALT plan. Numer- ical examples are given finally which demonstrate the equivalent SSALT plan to the baseline optimum CSALT plan reduces almost half of the test time while achieving approximately the same estimation errors of model parameters.展开更多
In this paper, the generalized Oldroyd-B with fractional calculus approach is used. An exact solution in terms of Fox-H function for flow past an accelerated horizontal plate in a rotating fluid is obtained by using d...In this paper, the generalized Oldroyd-B with fractional calculus approach is used. An exact solution in terms of Fox-H function for flow past an accelerated horizontal plate in a rotating fluid is obtained by using discrete Laplace transform method. A comparison among the influence of various parameters in the Oldroyd-B model and the angular velocity of the fluid on the velocity profiles is made through numerical method in graphic form.展开更多
Microarc oxidation(MAO) has become a promising technique for the surface modification of implants. Therefore, the aims of this study were to further quantitatively and qualitatively evaluate the osteointegration abi...Microarc oxidation(MAO) has become a promising technique for the surface modification of implants. Therefore, the aims of this study were to further quantitatively and qualitatively evaluate the osteointegration abilities of MAO-treated and smooth surface(SF) implants in vivo and to investigate the areas in which the superiority of MAO-treated implants are displayed. In a rabbit model,a comprehensive histomorphological, osteogenic, mineralizational, and integrative assessment was performed using light microscopy, fluorescence microscopy, confocal laser scanning microscopy, and radiographic analyses. Compared with the SF groups, the MAO-treated groups exhibited more active contact osteogenesis, as well as distant osteogenesis, under fluorescence examination, the mineral apposition rate was found to be greater for all of the MAO-treated implants, and the osteointegration index(OI) value was greater in the MAO-treated groups at different times. In conclusion, the calcium-rich amorphous layer created by MAO provided a better environment for osteointegration, with more active contact osteogenesis, a more rapid mineral apposition rate and greater OI values.展开更多
Objective:To compare the prognostic factors of mortality among melioidosis patients between lognormal accelerated failure time(AFT),Cox proportional hazards(PH),and Cox PH with time-varying coefficient(TVC)models.Meth...Objective:To compare the prognostic factors of mortality among melioidosis patients between lognormal accelerated failure time(AFT),Cox proportional hazards(PH),and Cox PH with time-varying coefficient(TVC)models.Methods:A retrospective study was conducted from 2014 to 2019 among 453 patients who were admitted to Hospital Sultanah Bahiyah,Kedah and Hospital Tuanku Fauziah,Perlis in Northern Malaysia due to confirmed-cultured melioidosis.The prognostic factors of mortality from melioidosis were obtained from AFT survival analysis,and Cox’s models and the findings were compared by using the goodness of fit methods.The analyses were done by using Stata SE version 14.0.Results:A total of 242 patients(53.4%)survived.In this study,the median survival time of melioidosis patients was 30.0 days(95%CI 0.0-60.9).Six significant prognostic factors were identified in the Cox PH model and Cox PH-TVC model.In AFT survival analysis,a total of seven significant prognostic factors were identified.The results were found to be only a slight difference between the identified prognostic factors among the models.AFT survival showed better results compared to Cox's models,with the lowest Akaike information criteria and best fitted Cox-snell residuals.Conclusions:AFT survival analysis provides more reliable results and can be used as an alternative statistical analysis for determining the prognostic factors of mortality in melioidosis patients in certain situations.展开更多
We report the results of protein folding (219M, C34, N36, 2KES, 2KHK) by the method of accelerated molecular dynamics (aMD) at room temperature with the implicit solvent model. Starting from the linear structures,...We report the results of protein folding (219M, C34, N36, 2KES, 2KHK) by the method of accelerated molecular dynamics (aMD) at room temperature with the implicit solvent model. Starting from the linear structures, these proteins successfully fold to the native structure in a lO0-ns aMD simulation. In contrast, they are failed under the traditional MD simulation in the same simulation time. Then we find that the lowest root mean square deviations of helix structures from the native structures are 0.36 A, 0.63 A, 0.52 A, 1.1 A and 0.78 A. What is more, native contacts, cluster and free energy analyses show that the results of the aMD method are in accordance with the experiment very well. All analyses show that the aMD can accelerate the simulation process, thus we may apply it to the field of computer aided drug designs.展开更多
Survival of HIV/AIDS patients is crucially dependent on comprehensive and targeted medical interventions such as supply of antiretroviral therapy and monitoring disease progression with CD4 T-cell counts. Statistical ...Survival of HIV/AIDS patients is crucially dependent on comprehensive and targeted medical interventions such as supply of antiretroviral therapy and monitoring disease progression with CD4 T-cell counts. Statistical modelling approaches are helpful towards this goal. This study aims at developing Bayesian joint models with assumed generalized error distribution (GED) for the longitudinal CD4 data and two accelerated failure time distributions, Lognormal and loglogistic, for the survival time of HIV/AIDS patients. Data are obtained from patients under antiretroviral therapy follow-up at Shashemene referral hospital during January 2006-January 2012 and at Bale Robe general hospital during January 2008-March 2015. The Bayesian joint models are defined through latent variables and association parameters and with specified non-informative prior distributions for the model parameters. Simulations are conducted using Gibbs sampler algorithm implemented in the WinBUGS software. The results of the analyses of the two different data sets show that distributions of measurement errors of the longitudinal CD4 variable follow the generalized error distribution with fatter tails than the normal distribution. The Bayesian joint GED loglogistic models fit better to the data sets compared to the lognormal cases. Findings reveal that patients’ health can be improved over time. Compared to the males, female patients gain more CD4 counts. Survival time of a patient is negatively affected by TB infection. Moreover, increase in number of opportunistic infection implies decline of CD4 counts. Patients’ age negatively affects the disease marker with no effects on survival time. Improving weight may improve survival time of patients. Bayesian joint models with GED and AFT distributions are found to be useful in modelling the longitudinal and survival processes. Thus we recommend the generalized error distributions for measurement errors of the longitudinal data under the Bayesian joint modelling. Further studies may investigate the models with various types of shared random effects and more covariates with predictions.展开更多
High-speed railway bridges are subjected to normative limitations concerning maximum permissible deck accelerations.For the design of these structures,the European norm EN 1991-2 introduces the high-speed load model(H...High-speed railway bridges are subjected to normative limitations concerning maximum permissible deck accelerations.For the design of these structures,the European norm EN 1991-2 introduces the high-speed load model(HSLM)—a set of point loads intended to include the effects of existing high-speed trains.Yet,the evolution of current trains and the recent development of new load models motivate a discussion regarding the limits of validity of the HSLM.For this study,a large number of randomly generated load models of articulated,conventional,and regular trains are tested and compared with the envelope of HSLM effects.For each type of train,two sets of 100,000 load models are considered:one abiding by the limits of the EN 1991-2 and another considering wider limits.This comparison is achieved using both a bridge-independent metric(train signatures)and dynamic analyses on a case study bridge(the Canelas bridge of the Portuguese Railway Network).For the latter,a methodology to decrease the computational cost of moving loads analysis is introduced.Results show that some theoretical load models constructed within the stipulated limits of the norm can lead to effects not covered by the HSLM.This is especially noted in conventional trains,where there is a relation with larger distances between centres of adjacent vehicle bogies.展开更多
Very high-energy electrons(VHEEs)are potential candidates for FLASH radiotherapy for deep-seated tumors.We proposed a compact VHEE facility based on an X-band high-gradient high-power technique.In this study,we invest...Very high-energy electrons(VHEEs)are potential candidates for FLASH radiotherapy for deep-seated tumors.We proposed a compact VHEE facility based on an X-band high-gradient high-power technique.In this study,we investigated and realized the first X-band backward traveling-wave(BTW)accelerating structure as the buncher for a VHEE facility.A method for calculating the parameters of single cell from the field distribution was introduced to simplify the design of the BTW structure.Time-domain circuit equations were applied to calculate the transient beam parameters of the buncher in the unsteady state.A prototype of the BTW structure with a thermionic cathode-diode electron gun was designed,fabricated,and tested at high power at the Tsinghua X-band high-power test stand.The structure successfully operated with 5-MW microwave pulses from the pulse compressor and outputted electron bunches with an energy of 8 MeV and a pulsed current of 108 mA.展开更多
The main objective of accelerated life tests in this setting is the recovery of the distribution of the random variable representing lifetime which is difficult to observe at a certain level of a given stress factor. ...The main objective of accelerated life tests in this setting is the recovery of the distribution of the random variable representing lifetime which is difficult to observe at a certain level of a given stress factor. A general model for accelerated life test is proposed that utilizes the inverse problem approach, that is, the variable is observe at different level/s and the transfer function is used to recover the elusive random variable (life time). The problem then is reduced to finding the transfer function. We derive some properties of the proposed general model. The Lognormal distribution and the Arrhenius model for lifetime are used as examples. Its relationship with the Cox proportional hazards model is also discussed.展开更多
In order to study the cross-linking density and aging constitutive relationship of HTPB coating during storage,the thermal accelerated aging tests at 0%,3%,6%and 9%prestrains were carried out.The crosslinking density ...In order to study the cross-linking density and aging constitutive relationship of HTPB coating during storage,the thermal accelerated aging tests at 0%,3%,6%and 9%prestrains were carried out.The crosslinking density of HTPB coating at different aging stages were tested using low-field^1 H NMR and the variation of cross-linking density was analyzed.The aging model of cross-linking density considering the chemical aging and the physical stretching factors was established.The uniaxial tensile tests were carried out on HTPB coating at different aging stages and the cross-linking density was introduced into Ogden hyperelastic constitutive model as a characterization parameter of correction coefficient.Combined with uniaxial tensile test results,a prestrain aging constitutive model of HTPB coating was established.The results show that the cross-linking density of HTPB coating increases rapidly at first and then slowly with the increase of thermal accelerated aging time without prestrain.Under prestrain conditions,the crosslinking density of HTPB coating decreases at the early stage,and increases rapidly at first and then slowly at the middle and late stages of thermal accelerated aging.The correlation coefficients of aging model of cross-linking density and aging constitutive model with test results are R>0.9500 and R>0.9900 respectively,which can be used to accurately describe the cross-linking density and aging constitutive relationship of HTPB coating under prestrain accelerated thermal aging conditions.展开更多
In this paper, we have studied the nonparameter accelerated failure time (AFT) additive regression model, whose covariates have a nonparametric effect on high-dimensional censored data. We give the asymptotic property...In this paper, we have studied the nonparameter accelerated failure time (AFT) additive regression model, whose covariates have a nonparametric effect on high-dimensional censored data. We give the asymptotic property of the penalty estimator based on GMCP in the nonparameter AFT model.展开更多
Aim Using animals as object of experiment to acquire various patterns of low cerebral blood pressure and reduced blood capacity in cerebral tissues of astronauts due to the load of acceleration. Methods The isotope ...Aim Using animals as object of experiment to acquire various patterns of low cerebral blood pressure and reduced blood capacity in cerebral tissues of astronauts due to the load of acceleration. Methods The isotope tracking technique was applied to mark the blood and record the dynamic curves of cerebral blood flow changes under various accelerations, and the relevant mathematical model was set up using the method of system recognition. Also the method of factor analyzing was used to select two out of the data collected by eight sensors as two factors. Results One of the two factors reflects the various patterns in the astronaut's upper body, the other for the lower body. Parameters of rise time, delay time and steady value reflect the results under different acceleration. Conclusion Whether for the upper body or the lower body, blood flow changes can be considered as a second order system model. This method provides a new technique and method of doing research on astronaut's endurance of acceleration and selecting astronauts.展开更多
To satisfy the need of high speed NC (numerical control) machining, an acceleration and deceleration (acc/dec) control model is proposed, and the speed curve is also constructed by the cubic polynomial. The proposed c...To satisfy the need of high speed NC (numerical control) machining, an acceleration and deceleration (acc/dec) control model is proposed, and the speed curve is also constructed by the cubic polynomial. The proposed control model provides continuity of acceleration, which avoids the intense vibration in high speed NC machining. Based on the discrete characteristic of the data sampling interpolation, the acc/dec control discrete mathematical model is also set up and the discrete expression of the theoretical deceleration length is obtained furthermore. Aiming at the question of hardly predetermining the deceleration point in acc/dec control before interpolation, the adaptive acc/dec control algorithm is deduced from the expressions of the theoretical deceleration length. The experimental result proves that the acc/dec control model has the characteristic of easy implementation, stable movement and low impact. The model has been applied in multi-axes high speed micro fabrication machining successfully.展开更多
With the theory of subcritical crack growth, we can deduce the fundamental equation of regional seismicity acceleration model. Applying this model to intraplate earthquake regions, we select three earthquake subplates...With the theory of subcritical crack growth, we can deduce the fundamental equation of regional seismicity acceleration model. Applying this model to intraplate earthquake regions, we select three earthquake subplates: North China Subplate, Chuan Dian Block and Xinjiang Subplate, and divide the three subplates into seven researched regions by the difference of seismicity and tectonic conditions. With the modified equation given by Sornette and Sammis (1995), we analysis the seismicity of each region. To those strong earthquakes already occurred in these region, the model can give close fitting of magnitude and occurrence time, and the result in this article indicates that the seismicity acceleration model can also be used for describing the seismicity of intraplate. In the article, we give the magnitude and occurrence time of possible strong earthquakes in Shanxi, Ordos, Bole Tuokexun, Ayinke Wuqia earthquake regions. In the same subplate or block, the earthquake periods for each earthquake region are similar in time interval. The constant α in model can be used to describe the intensity of regional seismicity, and for the Chinese Mainland, α is 0.4 generally. To the seismicity in Taiwan and other regions with complex tectonic conditions, the model does not fit well at present.展开更多
The correlation between outdoor exposure and indoor accelerated corrosion test for high polymer materials was investigated according to the variation of the functional group of exposure models aged. Environment aging ...The correlation between outdoor exposure and indoor accelerated corrosion test for high polymer materials was investigated according to the variation of the functional group of exposure models aged. Environment aging intensities at different zones ( Wuhan and Lasa with the same latitude ) and the influences of indoor accelerating factors including water and ultraviolet on weathering performant.e of high polymer materials were also studied by comparing different indoor accelerated corrosion testing results. The experimental results show that : by testing variations of carbonyl exponent of polythene ( which represented the degradation behavior of high polymer materials due to ultraviolet oxidation of douIole bond) and ultraviolet absorbance of polycarbonate (which represented the degradation behavior of high polymer materials due to abevacuation of branched chain ), the degradation behavior of high polymer materials could be studied. Carbonyl exponent of polythene exposed in Wuhan and Lasa for 1 year was equal to that exposed in indoor cycle ultraviolet for 128 h anti 170 It, respectively, the ultraviolet absorbance of polycarbonate exposed in Wuhan for 1 year was equal to that exposed in indoor cycle ultraviolet for 240 h. The ratio of environment aging intensity of Lasa to Wuhan was around 1.2. With the prolongation of cycle accelerated ultraviolet exposure time, the variations of carbonyl exponent of polythene and the ultraviolet absorbance of polycarbonate were in the same shape of first order exponential decay curiae. Accompanied with ultraviolet, the effect of water condensated on the sample on weathering performance of polythene was more .significant than that of polycarbonate.展开更多
An accelerated decay test and a natural decay test were conducted synchronically to explore the strength degradation of decaying wood members under long-term exposure to natural environment.A natural decay test was ca...An accelerated decay test and a natural decay test were conducted synchronically to explore the strength degradation of decaying wood members under long-term exposure to natural environment.A natural decay test was carried out to measure the bending strength,compressive strength parallel to grain and modulus of elasticity of the wood members,with 6 groups of specimens decayed in natural environment for 3 to 18 months respectively.To compare with corresponding decay test,in which 6 other groups of specimens were measured under accelerated conditions.The experimental data collected were evaluated by Pearson productmoment for the correlation.The results indicate that the mechanical properties of the accelerated decay were highly correlated with those in natural environment,both of which decreased in the same trend.Under the given test conditions,the mean value of the accelerated decay test data were curve-fitted to achieve the time-dependent degradation model of the bending strength,the compressive strength parallel to grain,as well as the modulus of elasticity.Due to the high correlation,the acceleration shift factors(ASF)of the two tests were derived,where the bending strength of 2.934,the compressive strength parallel to grain of 2.519 and the elastic modulus of 2.346 were employed to formulate the strength degradation models in the long-term natural environment.The results verify that the exponential functionσ=σ0e^(-βt)enables to exactly capture the degradation of the mechanical properties of wood members decayed in natural environment.展开更多
基金This work was supported by Open Fund Project of State Key Laboratory of Intelligent Vehicle Safety Technology by Grant with No.IVSTSKL-202311Key Projects of Science and Technology Research Programme of Chongqing Municipal Education Commission by Grant with No.KJZD-K202301505+1 种基金Cooperation Project between Chongqing Municipal Undergraduate Universities and Institutes Affiliated to the Chinese Academy of Sciences in 2021 by Grant with No.HZ2021015Chongqing Graduate Student Research Innovation Program by Grant with No.CYS240801.
文摘Massive computational complexity and memory requirement of artificial intelligence models impede their deploy-ability on edge computing devices of the Internet of Things(IoT).While Power-of-Two(PoT)quantization is pro-posed to improve the efficiency for edge inference of Deep Neural Networks(DNNs),existing PoT schemes require a huge amount of bit-wise manipulation and have large memory overhead,and their efficiency is bounded by the bottleneck of computation latency and memory footprint.To tackle this challenge,we present an efficient inference approach on the basis of PoT quantization and model compression.An integer-only scalar PoT quantization(IOS-PoT)is designed jointly with a distribution loss regularizer,wherein the regularizer minimizes quantization errors and training disturbances.Additionally,two-stage model compression is developed to effectively reduce memory requirement,and alleviate bandwidth usage in communications of networked heterogenous learning systems.The product look-up table(P-LUT)inference scheme is leveraged to replace bit-shifting with only indexing and addition operations for achieving low-latency computation and implementing efficient edge accelerators.Finally,comprehensive experiments on Residual Networks(ResNets)and efficient architectures with Canadian Institute for Advanced Research(CIFAR),ImageNet,and Real-world Affective Faces Database(RAF-DB)datasets,indicate that our approach achieves 2×∼10×improvement in the reduction of both weight size and computation cost in comparison to state-of-the-art methods.A P-LUT accelerator prototype is implemented on the Xilinx KV260 Field Programmable Gate Array(FPGA)platform for accelerating convolution operations,with performance results showing that P-LUT reduces memory footprint by 1.45×,achieves more than 3×power efficiency and 2×resource efficiency,compared to the conventional bit-shifting scheme.
基金The National Natural Science Foundation of China under contract No.42076214.
文摘Storm surge is often the marine disaster that poses the greatest threat to life and property in coastal areas.Accurate and timely issuance of storm surge warnings to take appropriate countermeasures is an important means to reduce storm surge-related losses.Storm surge numerical models are important for storm surge forecasting.To further improve the performance of the storm surge forecast models,we developed a numerical storm surge forecast model based on an unstructured spherical centroidal Voronoi tessellation(SCVT)grid.The model is based on shallow water equations in vector-invariant form,and is discretized by Arakawa C grid.The SCVT grid can not only better describe the coastline information but also avoid rigid transitions,and it has a better global consistency by generating high-resolution grids in the key areas through transition refinement.In addition,the simulation speed of the model is accelerated by using the openACC-based GPU acceleration technology to meet the timeliness requirements of operational ensemble forecast.It only takes 37 s to simulate a day in the coastal waters of China.The newly developed storm surge model was applied to simulate typhoon-induced storm surges in the coastal waters of China.The hindcast experiments on the selected representative typhoon-induced storm surge processes indicate that the model can reasonably simulate the distribution characteristics of storm surges.The simulated maximum storm surges and their occurrence times are consistent with the observed data at the representative tide gauge stations,and the mean absolute errors are 3.5 cm and 0.6 h respectively,showing high accuracy and application prospects.
基金Supported by the National Natural Science Foundation of China(12101476,12061091,11901134)the Fundamental Research Funds for the Central Universities(ZYTS23054,QTZX22054)+1 种基金the Yunnan Funda-mental Research Projects(202101AT070103)the Natural Science Basic Research Program of Shaanxi Province(2020JQ-285).
文摘Dependent competing risks model is a practical model in the analysis of lifetime and failure modes.The dependence can be captured using a statistical tool to explore the re-lationship among failure causes.In this paper,an Archimedean copula is chosen to describe the dependence in a constant-stress accelerated life test.We study the Archimedean copula based dependent competing risks model using parametric and nonparametric methods.The parametric likelihood inference is presented by deriving the general expression of likelihood function based on assumed survival Archimedean copula associated with the model parameter estimation.Combining the nonparametric estimation with progressive censoring and the non-parametric copula estimation,we introduce a nonparametric reliability estimation method given competing risks data.A simulation study and a real data analysis are conducted to show the performance of the estimation methods.
基金supported in part by the National Key Research and Development Program of China(No.2017YFE0300104)in part by National Natural Science Foundation of China(No.51821005)。
文摘The China Fusion Engineering Test Reactor plans to build a 200 k V/25 A acceleration grid power supply(AGPS)for the negative-ion-based neutral beam injector prototype system.The AGPS uses a rectifier-inverter-isolated step-up structure.There is a DC bus between the rectifier and the inverter.In order to limit DC bus voltage ripple and transient fluctuations,a large number of capacitors are used,which degrades the reliability of the power supply and occupies a large amount of space.This work finds that due to the difference in the turn-off time of the rectifier and the inverter,the capacitance mainly depends on the rectifier current when the inverter is turned off.On this basis,an active power filter(APF)scheme is proposed to absorb the current.To enhance the dynamic response ability of the APF,model predictive control is adopted.In this paper,the circuit structure of the APF is introduced,the prediction model is deduced,the corresponding control strategy and signal detection method are proposed,and the simulation and experimental results show that APF can track the transient current of the DC bus and reduce the voltage fluctuation significantly.
文摘The optimum design of equivalent accelerated life testing plan based on proportional hazards-proportional odds model using D-optimality is presented. The defined equivalent test plan is the test plan that has the same value of the determinant of Fisher information matrix. The equivalent test plan of step stress accelerated life testing (SSALT) to a baseline optimum constant stress accelerated life testing (CSALT) plan is obtained by adjusting the censoring time of SSALT and solving the optimization problem for each case to achieve the same value of the determinant of Fisher information matrix as in the baseline optimum CSALT plan. Numer- ical examples are given finally which demonstrate the equivalent SSALT plan to the baseline optimum CSALT plan reduces almost half of the test time while achieving approximately the same estimation errors of model parameters.
基金supported by The project supported by the Natural Science Foundation of Shandong Province of China (Y2007A06)
文摘In this paper, the generalized Oldroyd-B with fractional calculus approach is used. An exact solution in terms of Fox-H function for flow past an accelerated horizontal plate in a rotating fluid is obtained by using discrete Laplace transform method. A comparison among the influence of various parameters in the Oldroyd-B model and the angular velocity of the fluid on the velocity profiles is made through numerical method in graphic form.
文摘Microarc oxidation(MAO) has become a promising technique for the surface modification of implants. Therefore, the aims of this study were to further quantitatively and qualitatively evaluate the osteointegration abilities of MAO-treated and smooth surface(SF) implants in vivo and to investigate the areas in which the superiority of MAO-treated implants are displayed. In a rabbit model,a comprehensive histomorphological, osteogenic, mineralizational, and integrative assessment was performed using light microscopy, fluorescence microscopy, confocal laser scanning microscopy, and radiographic analyses. Compared with the SF groups, the MAO-treated groups exhibited more active contact osteogenesis, as well as distant osteogenesis, under fluorescence examination, the mineral apposition rate was found to be greater for all of the MAO-treated implants, and the osteointegration index(OI) value was greater in the MAO-treated groups at different times. In conclusion, the calcium-rich amorphous layer created by MAO provided a better environment for osteointegration, with more active contact osteogenesis, a more rapid mineral apposition rate and greater OI values.
文摘Objective:To compare the prognostic factors of mortality among melioidosis patients between lognormal accelerated failure time(AFT),Cox proportional hazards(PH),and Cox PH with time-varying coefficient(TVC)models.Methods:A retrospective study was conducted from 2014 to 2019 among 453 patients who were admitted to Hospital Sultanah Bahiyah,Kedah and Hospital Tuanku Fauziah,Perlis in Northern Malaysia due to confirmed-cultured melioidosis.The prognostic factors of mortality from melioidosis were obtained from AFT survival analysis,and Cox’s models and the findings were compared by using the goodness of fit methods.The analyses were done by using Stata SE version 14.0.Results:A total of 242 patients(53.4%)survived.In this study,the median survival time of melioidosis patients was 30.0 days(95%CI 0.0-60.9).Six significant prognostic factors were identified in the Cox PH model and Cox PH-TVC model.In AFT survival analysis,a total of seven significant prognostic factors were identified.The results were found to be only a slight difference between the identified prognostic factors among the models.AFT survival showed better results compared to Cox's models,with the lowest Akaike information criteria and best fitted Cox-snell residuals.Conclusions:AFT survival analysis provides more reliable results and can be used as an alternative statistical analysis for determining the prognostic factors of mortality in melioidosis patients in certain situations.
基金Supported by the National Natural Science Foundation of China under Grant Nos 31200545,11274206 and 11574184
文摘We report the results of protein folding (219M, C34, N36, 2KES, 2KHK) by the method of accelerated molecular dynamics (aMD) at room temperature with the implicit solvent model. Starting from the linear structures, these proteins successfully fold to the native structure in a lO0-ns aMD simulation. In contrast, they are failed under the traditional MD simulation in the same simulation time. Then we find that the lowest root mean square deviations of helix structures from the native structures are 0.36 A, 0.63 A, 0.52 A, 1.1 A and 0.78 A. What is more, native contacts, cluster and free energy analyses show that the results of the aMD method are in accordance with the experiment very well. All analyses show that the aMD can accelerate the simulation process, thus we may apply it to the field of computer aided drug designs.
文摘Survival of HIV/AIDS patients is crucially dependent on comprehensive and targeted medical interventions such as supply of antiretroviral therapy and monitoring disease progression with CD4 T-cell counts. Statistical modelling approaches are helpful towards this goal. This study aims at developing Bayesian joint models with assumed generalized error distribution (GED) for the longitudinal CD4 data and two accelerated failure time distributions, Lognormal and loglogistic, for the survival time of HIV/AIDS patients. Data are obtained from patients under antiretroviral therapy follow-up at Shashemene referral hospital during January 2006-January 2012 and at Bale Robe general hospital during January 2008-March 2015. The Bayesian joint models are defined through latent variables and association parameters and with specified non-informative prior distributions for the model parameters. Simulations are conducted using Gibbs sampler algorithm implemented in the WinBUGS software. The results of the analyses of the two different data sets show that distributions of measurement errors of the longitudinal CD4 variable follow the generalized error distribution with fatter tails than the normal distribution. The Bayesian joint GED loglogistic models fit better to the data sets compared to the lognormal cases. Findings reveal that patients’ health can be improved over time. Compared to the males, female patients gain more CD4 counts. Survival time of a patient is negatively affected by TB infection. Moreover, increase in number of opportunistic infection implies decline of CD4 counts. Patients’ age negatively affects the disease marker with no effects on survival time. Improving weight may improve survival time of patients. Bayesian joint models with GED and AFT distributions are found to be useful in modelling the longitudinal and survival processes. Thus we recommend the generalized error distributions for measurement errors of the longitudinal data under the Bayesian joint modelling. Further studies may investigate the models with various types of shared random effects and more covariates with predictions.
基金This work was financially supported by the Portuguese Foundation for Science and Technology(FCT)through the PhD scholarship PD/BD/143007/2018The authors would like also to acknowledge the financial support of the projects IN2TRACK2-Research into enhanced track and switch and crossing system 2 and IN2TRACK3-Research into optimised and future railway infrastructure funded by European funds through the H2020(SHIFT2RAIL Innovation Programme)and of the Base Funding-UIDB/04708/2020 of the CONSTRUCT-Instituto de I&D em Estruturas e Construções-funded by national funds through the FCT/MCTES(PIDDAC).
文摘High-speed railway bridges are subjected to normative limitations concerning maximum permissible deck accelerations.For the design of these structures,the European norm EN 1991-2 introduces the high-speed load model(HSLM)—a set of point loads intended to include the effects of existing high-speed trains.Yet,the evolution of current trains and the recent development of new load models motivate a discussion regarding the limits of validity of the HSLM.For this study,a large number of randomly generated load models of articulated,conventional,and regular trains are tested and compared with the envelope of HSLM effects.For each type of train,two sets of 100,000 load models are considered:one abiding by the limits of the EN 1991-2 and another considering wider limits.This comparison is achieved using both a bridge-independent metric(train signatures)and dynamic analyses on a case study bridge(the Canelas bridge of the Portuguese Railway Network).For the latter,a methodology to decrease the computational cost of moving loads analysis is introduced.Results show that some theoretical load models constructed within the stipulated limits of the norm can lead to effects not covered by the HSLM.This is especially noted in conventional trains,where there is a relation with larger distances between centres of adjacent vehicle bogies.
基金supported by the National Natural Science Foundation of China(No.11922504).
文摘Very high-energy electrons(VHEEs)are potential candidates for FLASH radiotherapy for deep-seated tumors.We proposed a compact VHEE facility based on an X-band high-gradient high-power technique.In this study,we investigated and realized the first X-band backward traveling-wave(BTW)accelerating structure as the buncher for a VHEE facility.A method for calculating the parameters of single cell from the field distribution was introduced to simplify the design of the BTW structure.Time-domain circuit equations were applied to calculate the transient beam parameters of the buncher in the unsteady state.A prototype of the BTW structure with a thermionic cathode-diode electron gun was designed,fabricated,and tested at high power at the Tsinghua X-band high-power test stand.The structure successfully operated with 5-MW microwave pulses from the pulse compressor and outputted electron bunches with an energy of 8 MeV and a pulsed current of 108 mA.
文摘The main objective of accelerated life tests in this setting is the recovery of the distribution of the random variable representing lifetime which is difficult to observe at a certain level of a given stress factor. A general model for accelerated life test is proposed that utilizes the inverse problem approach, that is, the variable is observe at different level/s and the transfer function is used to recover the elusive random variable (life time). The problem then is reduced to finding the transfer function. We derive some properties of the proposed general model. The Lognormal distribution and the Arrhenius model for lifetime are used as examples. Its relationship with the Cox proportional hazards model is also discussed.
基金supported by the National Defense Pre-Research Foundation of China[grant number ZS2015070132A12002]。
文摘In order to study the cross-linking density and aging constitutive relationship of HTPB coating during storage,the thermal accelerated aging tests at 0%,3%,6%and 9%prestrains were carried out.The crosslinking density of HTPB coating at different aging stages were tested using low-field^1 H NMR and the variation of cross-linking density was analyzed.The aging model of cross-linking density considering the chemical aging and the physical stretching factors was established.The uniaxial tensile tests were carried out on HTPB coating at different aging stages and the cross-linking density was introduced into Ogden hyperelastic constitutive model as a characterization parameter of correction coefficient.Combined with uniaxial tensile test results,a prestrain aging constitutive model of HTPB coating was established.The results show that the cross-linking density of HTPB coating increases rapidly at first and then slowly with the increase of thermal accelerated aging time without prestrain.Under prestrain conditions,the crosslinking density of HTPB coating decreases at the early stage,and increases rapidly at first and then slowly at the middle and late stages of thermal accelerated aging.The correlation coefficients of aging model of cross-linking density and aging constitutive model with test results are R>0.9500 and R>0.9900 respectively,which can be used to accurately describe the cross-linking density and aging constitutive relationship of HTPB coating under prestrain accelerated thermal aging conditions.
文摘In this paper, we have studied the nonparameter accelerated failure time (AFT) additive regression model, whose covariates have a nonparametric effect on high-dimensional censored data. We give the asymptotic property of the penalty estimator based on GMCP in the nonparameter AFT model.
文摘Aim Using animals as object of experiment to acquire various patterns of low cerebral blood pressure and reduced blood capacity in cerebral tissues of astronauts due to the load of acceleration. Methods The isotope tracking technique was applied to mark the blood and record the dynamic curves of cerebral blood flow changes under various accelerations, and the relevant mathematical model was set up using the method of system recognition. Also the method of factor analyzing was used to select two out of the data collected by eight sensors as two factors. Results One of the two factors reflects the various patterns in the astronaut's upper body, the other for the lower body. Parameters of rise time, delay time and steady value reflect the results under different acceleration. Conclusion Whether for the upper body or the lower body, blood flow changes can be considered as a second order system model. This method provides a new technique and method of doing research on astronaut's endurance of acceleration and selecting astronauts.
基金the Hi-Tech Research and Development Pro-gram (863) of China (No. 2006AA04Z233)the National NaturalScience Foundation of China (No. 50575205)the Natural ScienceFoundation of Zhejiang Province (Nos. Y104243 and Y105686),China
文摘To satisfy the need of high speed NC (numerical control) machining, an acceleration and deceleration (acc/dec) control model is proposed, and the speed curve is also constructed by the cubic polynomial. The proposed control model provides continuity of acceleration, which avoids the intense vibration in high speed NC machining. Based on the discrete characteristic of the data sampling interpolation, the acc/dec control discrete mathematical model is also set up and the discrete expression of the theoretical deceleration length is obtained furthermore. Aiming at the question of hardly predetermining the deceleration point in acc/dec control before interpolation, the adaptive acc/dec control algorithm is deduced from the expressions of the theoretical deceleration length. The experimental result proves that the acc/dec control model has the characteristic of easy implementation, stable movement and low impact. The model has been applied in multi-axes high speed micro fabrication machining successfully.
文摘With the theory of subcritical crack growth, we can deduce the fundamental equation of regional seismicity acceleration model. Applying this model to intraplate earthquake regions, we select three earthquake subplates: North China Subplate, Chuan Dian Block and Xinjiang Subplate, and divide the three subplates into seven researched regions by the difference of seismicity and tectonic conditions. With the modified equation given by Sornette and Sammis (1995), we analysis the seismicity of each region. To those strong earthquakes already occurred in these region, the model can give close fitting of magnitude and occurrence time, and the result in this article indicates that the seismicity acceleration model can also be used for describing the seismicity of intraplate. In the article, we give the magnitude and occurrence time of possible strong earthquakes in Shanxi, Ordos, Bole Tuokexun, Ayinke Wuqia earthquake regions. In the same subplate or block, the earthquake periods for each earthquake region are similar in time interval. The constant α in model can be used to describe the intensity of regional seismicity, and for the Chinese Mainland, α is 0.4 generally. To the seismicity in Taiwan and other regions with complex tectonic conditions, the model does not fit well at present.
基金Funded by Ministry of Science and Technology of China (No.50499331)
文摘The correlation between outdoor exposure and indoor accelerated corrosion test for high polymer materials was investigated according to the variation of the functional group of exposure models aged. Environment aging intensities at different zones ( Wuhan and Lasa with the same latitude ) and the influences of indoor accelerating factors including water and ultraviolet on weathering performant.e of high polymer materials were also studied by comparing different indoor accelerated corrosion testing results. The experimental results show that : by testing variations of carbonyl exponent of polythene ( which represented the degradation behavior of high polymer materials due to ultraviolet oxidation of douIole bond) and ultraviolet absorbance of polycarbonate (which represented the degradation behavior of high polymer materials due to abevacuation of branched chain ), the degradation behavior of high polymer materials could be studied. Carbonyl exponent of polythene exposed in Wuhan and Lasa for 1 year was equal to that exposed in indoor cycle ultraviolet for 128 h anti 170 It, respectively, the ultraviolet absorbance of polycarbonate exposed in Wuhan for 1 year was equal to that exposed in indoor cycle ultraviolet for 240 h. The ratio of environment aging intensity of Lasa to Wuhan was around 1.2. With the prolongation of cycle accelerated ultraviolet exposure time, the variations of carbonyl exponent of polythene and the ultraviolet absorbance of polycarbonate were in the same shape of first order exponential decay curiae. Accompanied with ultraviolet, the effect of water condensated on the sample on weathering performance of polythene was more .significant than that of polycarbonate.
基金supported by a grant from the National Natural Science Foundation of China(No.51208399)Natural Science Foundation of Hubei province of China(No.2018CFB645)Hubei Key Laboratory of Roadway Bridge and Structure Engineering(Wuhan University of Technology)(No.DQJJ201706).
文摘An accelerated decay test and a natural decay test were conducted synchronically to explore the strength degradation of decaying wood members under long-term exposure to natural environment.A natural decay test was carried out to measure the bending strength,compressive strength parallel to grain and modulus of elasticity of the wood members,with 6 groups of specimens decayed in natural environment for 3 to 18 months respectively.To compare with corresponding decay test,in which 6 other groups of specimens were measured under accelerated conditions.The experimental data collected were evaluated by Pearson productmoment for the correlation.The results indicate that the mechanical properties of the accelerated decay were highly correlated with those in natural environment,both of which decreased in the same trend.Under the given test conditions,the mean value of the accelerated decay test data were curve-fitted to achieve the time-dependent degradation model of the bending strength,the compressive strength parallel to grain,as well as the modulus of elasticity.Due to the high correlation,the acceleration shift factors(ASF)of the two tests were derived,where the bending strength of 2.934,the compressive strength parallel to grain of 2.519 and the elastic modulus of 2.346 were employed to formulate the strength degradation models in the long-term natural environment.The results verify that the exponential functionσ=σ0e^(-βt)enables to exactly capture the degradation of the mechanical properties of wood members decayed in natural environment.