Acne is a disease of the pilosebaceous unit affecting both teenagers and adults. The treatment of acne is sometimes frustrating due to the emergence of antibiotic resistance, skin irritation and lack of novel therapy....Acne is a disease of the pilosebaceous unit affecting both teenagers and adults. The treatment of acne is sometimes frustrating due to the emergence of antibiotic resistance, skin irritation and lack of novel therapy. Light and vacuum devices, also known as photopneumatic therapy, have been shown promising as a generally well-tolerated adjunctive treatment of acne vulgaris. We conducted a clinical study using such device to assess the efficacy and safety as an adjunctive treatment of acne in Taiwan Residents patients. Twenty patients received six sequential treatments every one to two weeks in the facial region. A 4 × 4 cm2 area on cheek was chosen as a control area and was not treated with photopneumatic device. Safety parameters and adverse events were recorded. VISIA Complexion Analysis System was used for image analysis on the improvement of four parameters, namely, pigmentation, pore reduction, redness and porphyrin levels. There was an overall improvement in pigmentation, pore size, redness and porphyrin levels on treatment areas. The treatment areas showed statistically significant improvement (p < 0.05) in pigmentation and pore sizes compared with the control areas using paired samples T-test. Mild and self-limiting localized adverse events, mostly focal petechiae or mild irritation, were reported. Our study has demonstrated that photopneumatic therapy is an effective, safe and relatively well-tolerated procedure in Taiwan Residents acne patients.展开更多
Acne is an inflammatory disease often affecting the boys and girls at the pubescent age, with a tendency of affecting the females aged 30-45 years. We have treated 56 cases of acne by auricular needle-embedding wi... Acne is an inflammatory disease often affecting the boys and girls at the pubescent age, with a tendency of affecting the females aged 30-45 years. We have treated 56 cases of acne by auricular needle-embedding with satisfactory therapeutic results as reported in the following.……展开更多
Aminolevulinic acid-based photodynamic therapy(ALA-PDT)is a safe and effective physical therapy for acne vulgaris that is widely used in clinical practice.To further standardize the clinical application of ALA-PDT in ...Aminolevulinic acid-based photodynamic therapy(ALA-PDT)is a safe and effective physical therapy for acne vulgaris that is widely used in clinical practice.To further standardize the clinical application of ALA-PDT in the treatment of acne,we created this updated consensus based on the 2011 version of the consensus on ALA-PDT for the treatment of acne vulgaris.In this document,we summarize the mechanisms of action of ALA-PDT and provide practical standards for patient selection,treatment parameters,administration procedures,and management of adverse reactions.Our aim was to provide guidance and treatment regimens for using ALA-PDT for acne vulgaris in clinical practice.展开更多
Acne scars are caused by inflammatory reactions,infections,and improper handling of acne lesions.Such scars have a high incidence and are difficult to treat.There are many methods currently used to treat acne scars,in...Acne scars are caused by inflammatory reactions,infections,and improper handling of acne lesions.Such scars have a high incidence and are difficult to treat.There are many methods currently used to treat acne scars,including medications,photoelectric technology,surgery,filling,chemical peeling,traditional Chinese medicine,biotherapy,and microneedle therapy,and many new methods are constantly emerging.However,there are still many issues,such as the lack of high-quality clinical studies,non-uniform treatment methods,and unsatisfactory therapeutic effects.The selection of appropriate methods for the comprehensive treatment of different types of acne scars at different stages in clinical practice remains challenging and is a research topic of great interest.From the perspective of evidence-based medicine,this consensus aims to provide a reference for the treatment of acne scars in clinical practice.展开更多
目的:研究滋阴清肝消痤汤治疗寻常痤疮的临床疗效及作用机理。方法:采用随机对照法对80例寻常痤疮进行临床疗效观察,治疗前后分别测定治疗组(滋阴清肝消痤汤组)和对照组(四环素组)患者血清睾酮、雌二醇水平,并进行体外抗菌试验。结果:...目的:研究滋阴清肝消痤汤治疗寻常痤疮的临床疗效及作用机理。方法:采用随机对照法对80例寻常痤疮进行临床疗效观察,治疗前后分别测定治疗组(滋阴清肝消痤汤组)和对照组(四环素组)患者血清睾酮、雌二醇水平,并进行体外抗菌试验。结果:治疗组48例,总有效率85.42%,对照组32例,总有效率84.38%,两组疗效差异无显著性(P>0.05)。滋阴清肝消痤汤对痤疮丙酸杆菌的最小抑菌浓度(MIC)是0.0125g/ml,对金黄色葡萄球菌的 MIC 是0.025g/ml。结论:该方具有明显的抗雄激素活性及温和的雌激素活性,有调节内分泌及杀菌抗炎的作用。展开更多
文摘Acne is a disease of the pilosebaceous unit affecting both teenagers and adults. The treatment of acne is sometimes frustrating due to the emergence of antibiotic resistance, skin irritation and lack of novel therapy. Light and vacuum devices, also known as photopneumatic therapy, have been shown promising as a generally well-tolerated adjunctive treatment of acne vulgaris. We conducted a clinical study using such device to assess the efficacy and safety as an adjunctive treatment of acne in Taiwan Residents patients. Twenty patients received six sequential treatments every one to two weeks in the facial region. A 4 × 4 cm2 area on cheek was chosen as a control area and was not treated with photopneumatic device. Safety parameters and adverse events were recorded. VISIA Complexion Analysis System was used for image analysis on the improvement of four parameters, namely, pigmentation, pore reduction, redness and porphyrin levels. There was an overall improvement in pigmentation, pore size, redness and porphyrin levels on treatment areas. The treatment areas showed statistically significant improvement (p < 0.05) in pigmentation and pore sizes compared with the control areas using paired samples T-test. Mild and self-limiting localized adverse events, mostly focal petechiae or mild irritation, were reported. Our study has demonstrated that photopneumatic therapy is an effective, safe and relatively well-tolerated procedure in Taiwan Residents acne patients.
文摘 Acne is an inflammatory disease often affecting the boys and girls at the pubescent age, with a tendency of affecting the females aged 30-45 years. We have treated 56 cases of acne by auricular needle-embedding with satisfactory therapeutic results as reported in the following.……
文摘Aminolevulinic acid-based photodynamic therapy(ALA-PDT)is a safe and effective physical therapy for acne vulgaris that is widely used in clinical practice.To further standardize the clinical application of ALA-PDT in the treatment of acne,we created this updated consensus based on the 2011 version of the consensus on ALA-PDT for the treatment of acne vulgaris.In this document,we summarize the mechanisms of action of ALA-PDT and provide practical standards for patient selection,treatment parameters,administration procedures,and management of adverse reactions.Our aim was to provide guidance and treatment regimens for using ALA-PDT for acne vulgaris in clinical practice.
文摘Acne scars are caused by inflammatory reactions,infections,and improper handling of acne lesions.Such scars have a high incidence and are difficult to treat.There are many methods currently used to treat acne scars,including medications,photoelectric technology,surgery,filling,chemical peeling,traditional Chinese medicine,biotherapy,and microneedle therapy,and many new methods are constantly emerging.However,there are still many issues,such as the lack of high-quality clinical studies,non-uniform treatment methods,and unsatisfactory therapeutic effects.The selection of appropriate methods for the comprehensive treatment of different types of acne scars at different stages in clinical practice remains challenging and is a research topic of great interest.From the perspective of evidence-based medicine,this consensus aims to provide a reference for the treatment of acne scars in clinical practice.
文摘目的:研究滋阴清肝消痤汤治疗寻常痤疮的临床疗效及作用机理。方法:采用随机对照法对80例寻常痤疮进行临床疗效观察,治疗前后分别测定治疗组(滋阴清肝消痤汤组)和对照组(四环素组)患者血清睾酮、雌二醇水平,并进行体外抗菌试验。结果:治疗组48例,总有效率85.42%,对照组32例,总有效率84.38%,两组疗效差异无显著性(P>0.05)。滋阴清肝消痤汤对痤疮丙酸杆菌的最小抑菌浓度(MIC)是0.0125g/ml,对金黄色葡萄球菌的 MIC 是0.025g/ml。结论:该方具有明显的抗雄激素活性及温和的雌激素活性,有调节内分泌及杀菌抗炎的作用。
