With the introduction of new drugs, the treatment of acne vulgaris has improved dramatically;however, there remains a considerable gap between treatment outcomes and patients’ treatment goals. This study aimed to det...With the introduction of new drugs, the treatment of acne vulgaris has improved dramatically;however, there remains a considerable gap between treatment outcomes and patients’ treatment goals. This study aimed to determine whether dermatologists’ guidance on appropriate skincare for skin symptoms such as post-inflammatory erythema and post-inflammatory hyperpigmentation (PIH), which are not covered by acne treatment, leads to an improvement in patients’ skin condition and patient satisfaction. Japanese women who had completed standard treatment for acne vulgaris and those with mild symptoms not requiring treatment were included in the study. The participants received instructions about skin care at the beginning of the study, which they continued to apply for 6 weeks. At the start and end of the study, participants were examined by a dermatologist;afterward, skin measurements, including skin color, skin surface lipid content, and image analysis by VISIA<sup>®</sup> Evolution, analysis of stratum corneum obtained from the skin surface, and Skindex-16 questionnaire for assessing quality of life (QOL), were performed. The following showed significant improvements: PIH score, number of inflammatory acne lesions, and number of non-inflammatory acne lesions observed via skin examination;skin surface lipid content and values of L* and a* obtained via instrumental measurement;n number of pore, texture, red spot, and pigmented spot obtained via by image analysis;and degree of multilayer exfoliation and interleukin-1α determined by analysis of epidermal stratum corneum. QOL measurement using Skindex-16 also improved significantly. Appropriate skin care guidance following standard acne vulgaris treatment is helpful in achieving patients’ treatment goals. .展开更多
Background: Acne vulgaris is a widely prevalent distressing problem among young adults and adolescents. Almost one-third of young people consider acne to be a major problem/burden. Less than half of acne diagnoses are...Background: Acne vulgaris is a widely prevalent distressing problem among young adults and adolescents. Almost one-third of young people consider acne to be a major problem/burden. Less than half of acne diagnoses are made by a physician, and acne is often self-managed. Objective: We aim to find the prevalence of acne among different age groups, treatment seeking behaviors and sources of knowledge about acne treatment. We also aim to determine impact of acne vulgaris on quality of life and psychology of patients. Design: A cross-sectional study. Setting: Jordan university hospital, Amman, Jordan. Subjects: Patients aged 15 - 35 years old who attended the family medicine clinic in Jordan University Hospital. Intervention: A self-administered questionnaire, consisted of three major parts, distributed during the period between August 2019 and October 2019. Results: Upon analyzing the data, 153 out of the 300 participants were found to have suffered or were still suffering from acne with a prevalence of 45%. The mean age at which the acne started was 16.20. There was a significant correlation between severity of acne and impact on life. More than half of the affected participants sought doctor help to treat their acne;patients depended on many sources of information to manage their acne. The majority of them reported the dermatologist as their source of information. Patients tended to use different methods of treatment to manage their acne. The cleanser was the most commonly used methods of treatment. Conclusion: Our article demonstrates that acne is a prevalent distressing problem among adolescents;it affects patients’ quality of life. Different modalities of treatment and sources of information were sought by patients. As family doctors, we emphasize the need for accessible, accurate, community-based education on the modalities of treatment of acne, and the importance of prompt medical attention toward its effect on quality of life.展开更多
OBJECTIVE: To culturally translate the cardiff acne disability index(CADI) into Korean, and to examine its relationship with clinical acne severity,pathological patterns, and general quality of life(Qo L).METHODS: The...OBJECTIVE: To culturally translate the cardiff acne disability index(CADI) into Korean, and to examine its relationship with clinical acne severity,pathological patterns, and general quality of life(Qo L).METHODS: The CADI was culturally and lin-guistically translated into Korean via translation,back-translation, and face validity test process. Two hundred and fifty-four Korean adolescents were asked to complete the Korean version of the CADI(K-CADI), the Phlegm Pattern, the Cold-Heat Pattern, and the Korean version of the General Health Questionnaires. A clinician estimated acne severity for the adolescents, using the Korean Acne Grading System. Finally, reliability and validity of the K-CADI was examined, and the relationships between acne severity, Phlegm, Cold, and Heat patterns, and Qo L level were examined via pathway analysis.RESULTS: The K-CADI had satisfactory internal consistency(α = 0.827). The examination of construct validity indicated that the K-CADI had one factor(explaining 59.6% of the total variance). Pathway analysis showed satisfactory model fit(normal fit index = 0.960 and comparative fit index = 0.983),and acne-related Qo L was determinant to Phlegm,Heat, and Cold patterns(0.13-0.27 of β), and Phlegm and Heat patterns lowered one's Qo L level(0.17-0.34 of β).CONCLUSION: The K-CADI is a valid and reliable instrument. Phlegm and Heat patterns should be managed when treating acne since they have a moderating effect on general Qo L aggravation.展开更多
目的观察温针灸联合放血疗法对痤疮患者皮损程度、皮肤病生活质量指数(dermatology life quality index,DLQI)评分及复发率的影响。方法 120例湿热型痤疮患者随机分为观察组和对照组,每组60例。对照组采用放血疗法,观察组在对照组基础...目的观察温针灸联合放血疗法对痤疮患者皮损程度、皮肤病生活质量指数(dermatology life quality index,DLQI)评分及复发率的影响。方法 120例湿热型痤疮患者随机分为观察组和对照组,每组60例。对照组采用放血疗法,观察组在对照组基础上联合温针灸治疗。观察两组患者治疗前后皮损程度、DLQI评分、中医症候评分变化,比较两组的临床疗效、不良反应发生率及复发率。结果观察组总有效率显著高于对照组(P<0.05)。两组治疗后皮损个数显著减少(P<0.05),且观察组皮损个数少于对照组(P<0.05),皮损减少率大于对照组(P<0.05)。治疗后两组DLQI评分、中医症候评分均显著降低(P<0.05),且观察组低于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。治疗组复发率显著低于对照组(P<0.05)。结论温针灸联合放血疗法治疗湿热型痤疮疗效佳,不良反应率低,复发率低,疗效稳定。展开更多
目的:探讨清热除湿汤加减联合强脉冲光(Intense pulsed light,IPL)治疗轻中度脾胃湿热型玫瑰痤疮的疗效。方法:选取2018年2月-2021年2月在笔者医院确诊的100例轻中度脾胃湿热型玫瑰痤疮患者,采用简单随机分组将患者分为观察组和对照组,...目的:探讨清热除湿汤加减联合强脉冲光(Intense pulsed light,IPL)治疗轻中度脾胃湿热型玫瑰痤疮的疗效。方法:选取2018年2月-2021年2月在笔者医院确诊的100例轻中度脾胃湿热型玫瑰痤疮患者,采用简单随机分组将患者分为观察组和对照组,每组50例。对照组采用IPL治疗,观察组采用清热除湿汤加减联合IPL治疗,均持续治疗4个月。评价患者疗效和治疗前后中医证候积分。分别于治疗前后采用玫瑰痤疮医师全球评分(Physician’s global assessment,PGA)对患者玫瑰痤疮情况进行评分;分别于治疗前、治疗后2个月和治疗后4个月,使用皮肤病生活质量指数量表(Dermatology life quality index,DLQI)评估患者生活质量。记录两组治疗期间的不良反应发生情况。结果:观察组治疗有效率为92.00%,明显高于对照组的76.00%,差异有统计学意义(P<0.05);治疗后,观察组中医证候积分明显低于对照组,观察组患者玫瑰痤疮改善程度明显优于对照组,生活质量明显高于对照组,差异均有统计学意义(P<0.05)。观察组患者治疗期间的不良反应发生率为10.00%,与对照组(14.00%)比较差异无统计学意义(P>0.05)。结论:清热除湿汤加减联合IPL治疗轻中度脾胃湿热型玫瑰痤疮可明显提高临床疗效,改善患者生活质量。展开更多
文摘With the introduction of new drugs, the treatment of acne vulgaris has improved dramatically;however, there remains a considerable gap between treatment outcomes and patients’ treatment goals. This study aimed to determine whether dermatologists’ guidance on appropriate skincare for skin symptoms such as post-inflammatory erythema and post-inflammatory hyperpigmentation (PIH), which are not covered by acne treatment, leads to an improvement in patients’ skin condition and patient satisfaction. Japanese women who had completed standard treatment for acne vulgaris and those with mild symptoms not requiring treatment were included in the study. The participants received instructions about skin care at the beginning of the study, which they continued to apply for 6 weeks. At the start and end of the study, participants were examined by a dermatologist;afterward, skin measurements, including skin color, skin surface lipid content, and image analysis by VISIA<sup>®</sup> Evolution, analysis of stratum corneum obtained from the skin surface, and Skindex-16 questionnaire for assessing quality of life (QOL), were performed. The following showed significant improvements: PIH score, number of inflammatory acne lesions, and number of non-inflammatory acne lesions observed via skin examination;skin surface lipid content and values of L* and a* obtained via instrumental measurement;n number of pore, texture, red spot, and pigmented spot obtained via by image analysis;and degree of multilayer exfoliation and interleukin-1α determined by analysis of epidermal stratum corneum. QOL measurement using Skindex-16 also improved significantly. Appropriate skin care guidance following standard acne vulgaris treatment is helpful in achieving patients’ treatment goals. .
文摘Background: Acne vulgaris is a widely prevalent distressing problem among young adults and adolescents. Almost one-third of young people consider acne to be a major problem/burden. Less than half of acne diagnoses are made by a physician, and acne is often self-managed. Objective: We aim to find the prevalence of acne among different age groups, treatment seeking behaviors and sources of knowledge about acne treatment. We also aim to determine impact of acne vulgaris on quality of life and psychology of patients. Design: A cross-sectional study. Setting: Jordan university hospital, Amman, Jordan. Subjects: Patients aged 15 - 35 years old who attended the family medicine clinic in Jordan University Hospital. Intervention: A self-administered questionnaire, consisted of three major parts, distributed during the period between August 2019 and October 2019. Results: Upon analyzing the data, 153 out of the 300 participants were found to have suffered or were still suffering from acne with a prevalence of 45%. The mean age at which the acne started was 16.20. There was a significant correlation between severity of acne and impact on life. More than half of the affected participants sought doctor help to treat their acne;patients depended on many sources of information to manage their acne. The majority of them reported the dermatologist as their source of information. Patients tended to use different methods of treatment to manage their acne. The cleanser was the most commonly used methods of treatment. Conclusion: Our article demonstrates that acne is a prevalent distressing problem among adolescents;it affects patients’ quality of life. Different modalities of treatment and sources of information were sought by patients. As family doctors, we emphasize the need for accessible, accurate, community-based education on the modalities of treatment of acne, and the importance of prompt medical attention toward its effect on quality of life.
文摘OBJECTIVE: To culturally translate the cardiff acne disability index(CADI) into Korean, and to examine its relationship with clinical acne severity,pathological patterns, and general quality of life(Qo L).METHODS: The CADI was culturally and lin-guistically translated into Korean via translation,back-translation, and face validity test process. Two hundred and fifty-four Korean adolescents were asked to complete the Korean version of the CADI(K-CADI), the Phlegm Pattern, the Cold-Heat Pattern, and the Korean version of the General Health Questionnaires. A clinician estimated acne severity for the adolescents, using the Korean Acne Grading System. Finally, reliability and validity of the K-CADI was examined, and the relationships between acne severity, Phlegm, Cold, and Heat patterns, and Qo L level were examined via pathway analysis.RESULTS: The K-CADI had satisfactory internal consistency(α = 0.827). The examination of construct validity indicated that the K-CADI had one factor(explaining 59.6% of the total variance). Pathway analysis showed satisfactory model fit(normal fit index = 0.960 and comparative fit index = 0.983),and acne-related Qo L was determinant to Phlegm,Heat, and Cold patterns(0.13-0.27 of β), and Phlegm and Heat patterns lowered one's Qo L level(0.17-0.34 of β).CONCLUSION: The K-CADI is a valid and reliable instrument. Phlegm and Heat patterns should be managed when treating acne since they have a moderating effect on general Qo L aggravation.
文摘目的观察温针灸联合放血疗法对痤疮患者皮损程度、皮肤病生活质量指数(dermatology life quality index,DLQI)评分及复发率的影响。方法 120例湿热型痤疮患者随机分为观察组和对照组,每组60例。对照组采用放血疗法,观察组在对照组基础上联合温针灸治疗。观察两组患者治疗前后皮损程度、DLQI评分、中医症候评分变化,比较两组的临床疗效、不良反应发生率及复发率。结果观察组总有效率显著高于对照组(P<0.05)。两组治疗后皮损个数显著减少(P<0.05),且观察组皮损个数少于对照组(P<0.05),皮损减少率大于对照组(P<0.05)。治疗后两组DLQI评分、中医症候评分均显著降低(P<0.05),且观察组低于对照组(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。治疗组复发率显著低于对照组(P<0.05)。结论温针灸联合放血疗法治疗湿热型痤疮疗效佳,不良反应率低,复发率低,疗效稳定。
文摘目的:探讨清热除湿汤加减联合强脉冲光(Intense pulsed light,IPL)治疗轻中度脾胃湿热型玫瑰痤疮的疗效。方法:选取2018年2月-2021年2月在笔者医院确诊的100例轻中度脾胃湿热型玫瑰痤疮患者,采用简单随机分组将患者分为观察组和对照组,每组50例。对照组采用IPL治疗,观察组采用清热除湿汤加减联合IPL治疗,均持续治疗4个月。评价患者疗效和治疗前后中医证候积分。分别于治疗前后采用玫瑰痤疮医师全球评分(Physician’s global assessment,PGA)对患者玫瑰痤疮情况进行评分;分别于治疗前、治疗后2个月和治疗后4个月,使用皮肤病生活质量指数量表(Dermatology life quality index,DLQI)评估患者生活质量。记录两组治疗期间的不良反应发生情况。结果:观察组治疗有效率为92.00%,明显高于对照组的76.00%,差异有统计学意义(P<0.05);治疗后,观察组中医证候积分明显低于对照组,观察组患者玫瑰痤疮改善程度明显优于对照组,生活质量明显高于对照组,差异均有统计学意义(P<0.05)。观察组患者治疗期间的不良反应发生率为10.00%,与对照组(14.00%)比较差异无统计学意义(P>0.05)。结论:清热除湿汤加减联合IPL治疗轻中度脾胃湿热型玫瑰痤疮可明显提高临床疗效,改善患者生活质量。
