Dear Editor, RND (resistance nodulation-cell division) exporters are widely expressed across the lineage of Gram-negative bacteria (Fig. S1 ). Their functional role is to utilize the protonmotive force of the cell...Dear Editor, RND (resistance nodulation-cell division) exporters are widely expressed across the lineage of Gram-negative bacteria (Fig. S1 ). Their functional role is to utilize the protonmotive force of the cell to drive the expulsion of cytotoxic substances from the outer leaflet of the inner membrane as well as the periplasm to extracellular space (Yamaguchi et al., 2015).展开更多
基金The authors thank Dr. Yong Tao of the Institute of Microbiology, CAS, for providing the ΔacrB cell strain. We thank Dr. Torsten Juelich for linguistic assistance during the preparation of this manuscript. This work was supported by the National Basic Research Program (973 Program) (No. 2015CB910104 to XCZ) and National Natural Science Foundation of China (Grant No. 31470745 to XCZ).
文摘Dear Editor, RND (resistance nodulation-cell division) exporters are widely expressed across the lineage of Gram-negative bacteria (Fig. S1 ). Their functional role is to utilize the protonmotive force of the cell to drive the expulsion of cytotoxic substances from the outer leaflet of the inner membrane as well as the periplasm to extracellular space (Yamaguchi et al., 2015).